4E3C
X-ray crystal structure of human IKK2 in an active conformation
Summary for 4E3C
Entry DOI | 10.2210/pdb4e3c/pdb |
Descriptor | Inhibitor of nuclear factor kappa-B kinase subunit beta (1 entity in total) |
Functional Keywords | kanase, auto-phosphorylation, nemo binding, transferase |
Biological source | Homo sapiens (human) |
Cellular location | Cytoplasm: O14920 |
Total number of polymer chains | 6 |
Total formula weight | 462981.14 |
Authors | Polley, S.,Huang, D.B.,Hauenstein, A.V.,Ghosh, G.,Huxford, T. (deposition date: 2012-03-09, release date: 2013-06-19, Last modification date: 2023-09-13) |
Primary citation | Polley, S.,Huang, D.B.,Hauenstein, A.V.,Fusco, A.J.,Zhong, X.,Vu, D.,Hoffmann, A.,Verma, I.V.,Ghosh, G.,Huaford, T. X-ray crystal structure of human IKK2 in an active conformation Plos.Biol., 2013 |
Experimental method | X-RAY DIFFRACTION (3.98 Å) |
Structure validation
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