4TTC
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4ttc by Molmil](/molmil-images/mine/4ttc) | |
1VSQ
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1vsq by Molmil](/molmil-images/mine/1vsq) | |
8ZMN
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8zmn by Molmil](/molmil-images/mine/8zmn) | Crystal structure of ANTXR1 | Descriptor: | Anthrax toxin receptor 1, SODIUM ION | Authors: | Zheng, H, Hu, J, Fu, L, Chen, R. | Deposit date: | 2024-05-23 | Release date: | 2024-06-26 | Method: | X-RAY DIFFRACTION (2.14 Å) | Cite: | X-ray structure of Anthrax toxin receptor 1 APO from Rattus norvegicus To Be Published
|
|
7CTF
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7ctf by Molmil](/molmil-images/mine/7ctf) | Human origin recognition complex 1-5 State II | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, Origin recognition complex subunit 1, Origin recognition complex subunit 2, ... | Authors: | Cheng, J, Li, N, Wang, X, Hu, J, Zhai, Y, Gao, N. | Deposit date: | 2020-08-18 | Release date: | 2021-01-06 | Last modified: | 2024-03-27 | Method: | ELECTRON MICROSCOPY (4.8 Å) | Cite: | Structural insight into the assembly and conformational activation of human origin recognition complex. Cell Discov, 6, 2020
|
|
7CTE
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7cte by Molmil](/molmil-images/mine/7cte) | Human Origin Recognition Complex, ORC2-5 | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, Origin recognition complex subunit 2, Origin recognition complex subunit 3, ... | Authors: | Cheng, J, Li, N, Wang, X, Hu, J, Zhai, Y, Gao, N. | Deposit date: | 2020-08-18 | Release date: | 2021-01-06 | Last modified: | 2024-03-27 | Method: | ELECTRON MICROSCOPY (3.8 Å) | Cite: | Structural insight into the assembly and conformational activation of human origin recognition complex. Cell Discov, 6, 2020
|
|
7CTG
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7ctg by Molmil](/molmil-images/mine/7ctg) | Human Origin Recognition Complex, ORC1-5 State I | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, Origin recognition complex subunit 1, Origin recognition complex subunit 2, ... | Authors: | Cheng, J, Li, N, Wang, X, Hu, J, Zhai, Y, Gao, N. | Deposit date: | 2020-08-18 | Release date: | 2021-01-06 | Last modified: | 2024-03-27 | Method: | ELECTRON MICROSCOPY (5 Å) | Cite: | Structural insight into the assembly and conformational activation of human origin recognition complex. Cell Discov, 6, 2020
|
|
5CB2
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5cb2 by Molmil](/molmil-images/mine/5cb2) | the structure of candida albicans Sey1p in complex with GMPPNP | Descriptor: | MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, Protein SEY1 | Authors: | Yan, L, Sun, S, Wang, W, Shi, J, Hu, X, Wang, S, Rao, Z, Hu, J, Lou, Z. | Deposit date: | 2015-06-30 | Release date: | 2015-09-23 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | Structures of the yeast dynamin-like GTPase Sey1p provide insight into homotypic ER fusion J.Cell Biol., 210, 2015
|
|
8UC2
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8uc2 by Molmil](/molmil-images/mine/8uc2) | Ethylene forming enzyme (EFE) R171A variant in complex with nickel and Benzoic acid | Descriptor: | 1,2-ETHANEDIOL, 2-oxoglutarate-dependent ethylene/succinate-forming enzyme, BENZOIC ACID, ... | Authors: | Chatterjee, S, Rankin, J.A, Hu, J, Hausinger, R. | Deposit date: | 2023-09-25 | Release date: | 2023-10-04 | Last modified: | 2024-05-01 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Structural, Spectroscopic, and Computational Insights from Canavanine-Bound and Two Catalytically Compromised Variants of the Ethylene-Forming Enzyme. Biochemistry, 63, 2024
|
|
7E2R
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7e2r by Molmil](/molmil-images/mine/7e2r) | The ligand-free structure of Arabidopsis thaliana GUN4 | Descriptor: | Tetrapyrrole-binding protein, chloroplastic | Authors: | Liu, L, Hu, J. | Deposit date: | 2021-02-07 | Release date: | 2021-08-25 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Structural basis of bilin binding by the chlorophyll biosynthesis regulator GUN4. Protein Sci., 30, 2021
|
|
6PGI
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6pgi by Molmil](/molmil-images/mine/6pgi) | Asymmetric functions of a binuclear metal cluster within the transport pathway of the ZIP transition metal transporters | Descriptor: | BbZIP, CADMIUM ION | Authors: | Zhang, T, Sui, D, Zhang, C, Logan, T, Hu, J. | Deposit date: | 2019-06-24 | Release date: | 2019-12-11 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (3.5 Å) | Cite: | Asymmetric functions of a binuclear metal center within the transport pathway of a human zinc transporter ZIP4. Faseb J., 34, 2020
|
|
7XNE
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7xne by Molmil](/molmil-images/mine/7xne) | Crystal structure of CBP bromodomain liganded with Y08284 | Descriptor: | CREB-binding protein, GLYCEROL, N-[3-(1-cyclopropylpyrazol-4-yl)-2-fluoranyl-5-[(1S)-1-oxidanylethyl]phenyl]-3-ethanoyl-7-methoxy-indolizine-1-carboxamide | Authors: | Xiang, Q, Wang, C, Wu, T, Zhang, C, Hu, Q, Luo, G, Hu, J, Zhuang, X, Zou, L, Shen, H, Wu, X, Zhang, Y, Kong, X, Xu, Y. | Deposit date: | 2022-04-28 | Release date: | 2022-07-06 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.17 Å) | Cite: | Design, Synthesis, and Biological Evaluation of 1-(Indolizin-3-yl)ethan-1-ones as CBP Bromodomain Inhibitors for the Treatment of Prostate Cancer. J.Med.Chem., 65, 2022
|
|
7E2U
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7e2u by Molmil](/molmil-images/mine/7e2u) | Synechocystis GUN4 in complex with phytochrome | Descriptor: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 3-[5-[(~{Z})-(4-ethenyl-3-methyl-5-oxidanylidene-pyrrol-2-ylidene)methyl]-2-[(~{Z})-[5-[(~{Z})-[(4~{R})-3-ethyl-4-methyl-5-oxidanylidene-pyrrolidin-2-ylidene]methyl]-3-(3-hydroxy-3-oxopropyl)-4-methyl-pyrrol-2-ylidene]methyl]-4-methyl-1~{H}-pyrrol-3-yl]propanoic acid, CHLORIDE ION, ... | Authors: | Liu, L, Hu, J. | Deposit date: | 2021-02-07 | Release date: | 2021-08-25 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Structural basis of bilin binding by the chlorophyll biosynthesis regulator GUN4. Protein Sci., 30, 2021
|
|
7E2T
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7e2t by Molmil](/molmil-images/mine/7e2t) | Synechocystis GUN4 in complex with phycocyanobilin | Descriptor: | 3-[2-[(~{Z})-[5-[(~{Z})-[(4~{R})-3-ethylidene-4-methyl-5-oxidanylidene-pyrrolidin-2-ylidene]methyl]-3-(3-hydroxy-3-oxopropyl)-4-methyl-pyrrol-2-ylidene]methyl]-5-[(~{Z})-(4-ethyl-3-methyl-5-oxidanylidene-pyrrol-2-ylidene)methyl]-4-methyl-1~{H}-pyrrol-3-yl]propanoic acid, CHLORIDE ION, Ycf53-like protein | Authors: | Liu, L, Hu, J. | Deposit date: | 2021-02-07 | Release date: | 2021-08-25 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.1 Å) | Cite: | Structural basis of bilin binding by the chlorophyll biosynthesis regulator GUN4. Protein Sci., 30, 2021
|
|
7E2S
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7e2s by Molmil](/molmil-images/mine/7e2s) | Synechocystis GUN4 in complex with biliverdin IXa | Descriptor: | BILIVERDINE IX ALPHA, GLYCEROL, Ycf53-like protein | Authors: | Liu, L, Hu, J. | Deposit date: | 2021-02-07 | Release date: | 2021-08-25 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.05 Å) | Cite: | Structural basis of bilin binding by the chlorophyll biosynthesis regulator GUN4. Protein Sci., 30, 2021
|
|
5YOV
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5yov by Molmil](/molmil-images/mine/5yov) | Crystal structure of BRD4-BD1 bound with hjp126 | Descriptor: | (3~{R})-4-cyclopentyl-~{N}-(2,4-dimethylphenyl)-1,3-dimethyl-2-oxidanylidene-3~{H}-quinoxaline-6-carboxamide, Bromodomain-containing protein 4 | Authors: | Xiong, B, Hu, J, Li, Y, Cao, D. | Deposit date: | 2017-10-31 | Release date: | 2018-11-07 | Last modified: | 2024-03-27 | Method: | X-RAY DIFFRACTION (1.451 Å) | Cite: | Structure-based optimization of a series of selective BET inhibitors containing aniline or indoline groups. Eur.J.Med.Chem., 150, 2018
|
|
5ZJL
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5zjl by Molmil](/molmil-images/mine/5zjl) | |
6OC6
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6oc6 by Molmil](/molmil-images/mine/6oc6) | Lanthanide-dependent methanol dehydrogenase XoxF from Methylobacterium extorquens, in complex with Lanthanum and Pyrroloquinoline quinone | Descriptor: | LANTHANUM (III) ION, Lanthanide-dependent methanol dehydrogenase XoxF, PYRROLOQUINOLINE QUINONE | Authors: | Fellner, M, Good, N.M, Martinez-Gomez, N.C, Hausinger, R.P, Hu, J. | Deposit date: | 2019-03-21 | Release date: | 2020-05-13 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (2.89 Å) | Cite: | Lanthanide-dependent alcohol dehydrogenases require an essential aspartate residue for metal coordination and enzymatic function. J.Biol.Chem., 295, 2020
|
|
6JTG
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6jtg by Molmil](/molmil-images/mine/6jtg) | |
6LKA
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6lka by Molmil](/molmil-images/mine/6lka) | Crystal Structure of EV71-3C protease with a Novel Macrocyclic Compounds | Descriptor: | 3C proteinase, ~{N}-[(2~{S})-1-[[(2~{S},3~{S},6~{S},7~{Z},12~{E})-4,9-bis(oxidanylidene)-6-[[(3~{S})-2-oxidanylidenepyrrolidin-3-yl]methyl]-2-phenyl-1,10-dioxa-5-azacyclopentadeca-7,12-dien-3-yl]amino]-3-methyl-1-oxidanylidene-butan-2-yl]-5-methyl-1,2-oxazole-3-carboxamide | Authors: | Li, P, Wu, S.Q, Xiao, T.Y.C, Li, Y.L, Su, Z.M, Hao, F, Hu, G.P, Hu, J, Lin, F.S, Chen, X.S, Gu, Z.X, He, H.Y, Li, J, Chen, S.H. | Deposit date: | 2019-12-18 | Release date: | 2020-06-17 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.033 Å) | Cite: | Design, synthesis, and evaluation of a novel macrocyclic anti-EV71 agent. Bioorg.Med.Chem., 28, 2020
|
|
1XZ0
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1xz0 by Molmil](/molmil-images/mine/1xz0) | Crystal structure of CD1a in complex with a synthetic mycobactin lipopeptide | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, 6-(HYDROXY-HEXADECANOYL-AMINO)-2-{[(4S)-2-(2-HYDROXY-PHENYL)-4,5-DIHYDRO-OXAZOLE-4-CARBONYL]-AMINO}-HEXANOIC ACID 2-[(3S)-1-(TERT-BUTYL-DIPHENYL-SILANYLOXY)-2-OXO-AZEPAN-3-YLCARBAMOYL]-(1S)-1-METHYL-ETHYL ESTER, Beta-2-microglobulin, ... | Authors: | Zajonc, D.M, Crispin, M.D, Bowden, T.A, Young, D.C, Cheng, T.Y, Hu, J, Costello, C.E, Miller, M.J, Moody, D.B, Wilson, I.A. | Deposit date: | 2004-11-11 | Release date: | 2005-03-01 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Molecular Mechanism of Lipopeptide Presentation by CD1a. Immunity, 22, 2005
|
|
5YDT
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5ydt by Molmil](/molmil-images/mine/5ydt) | Remodeled Utp30 in 90S pre-ribosome (Mtr4-depleted, Enp1-TAP) | Descriptor: | 5' ETS RNA, Ribosome biogenesis protein UTP30, Saccharomyces cerevisiae strain ALI 308 18S ribosomal RNA gene, ... | Authors: | Ye, K, Zhu, X, Hu, J. | Deposit date: | 2017-09-14 | Release date: | 2017-11-01 | Last modified: | 2024-03-27 | Method: | ELECTRON MICROSCOPY (4.5 Å) | Cite: | Structure and RNA recognition of ribosome assembly factor Utp30. RNA, 23, 2017
|
|
7WNT
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7wnt by Molmil](/molmil-images/mine/7wnt) | RNase J from Mycobacterium tuberculosis | Descriptor: | Ribonuclease J, ZINC ION | Authors: | Li, J, Bao, L, Hu, J, Zhan, B, Li, Z. | Deposit date: | 2022-01-19 | Release date: | 2023-01-25 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.44 Å) | Cite: | Structural ans functional study of RNase J from Mycobacterium tuberculosis To Be Published
|
|
7WNU
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7wnu by Molmil](/molmil-images/mine/7wnu) | Mycobacterium tuberculosis Rnase J complex with 7nt RNA | Descriptor: | RNA (5'-R(P*AP*AP*AP*AP*AP*AP*A)-3'), Ribonuclease J, ZINC ION | Authors: | Li, J, Hu, J, Bao, L, Zhan, B, Li, Z. | Deposit date: | 2022-01-19 | Release date: | 2023-01-25 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (3.2 Å) | Cite: | Structural ans functional study of RNase J from Mycobacterium tuberculosis To Be Published
|
|
5GNS
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5gns by Molmil](/molmil-images/mine/5gns) | Structures of human Mitofusin 1 provide insight into mitochondrial tethering | Descriptor: | GUANOSINE-5'-TRIPHOSPHATE, Mitofusin-1 | Authors: | Qi, Y, Yan, L, Yu, C, Guo, X, Zhou, X, Hu, X, Huang, X, Rao, Z, Lou, Z, Hu, J. | Deposit date: | 2016-07-24 | Release date: | 2016-12-07 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (2.702 Å) | Cite: | Structures of human Mitofusin 1 provide insight into mitochondrial tethering To Be Published
|
|
2AUG
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2aug by Molmil](/molmil-images/mine/2aug) | Crystal structure of the Grb14 SH2 domain | Descriptor: | Growth factor receptor-bound protein 14 | Authors: | Depetris, R.S, Hu, J, Gimpelevich, I, Holt, L.J, Daly, R.J, Hubbard, S.R. | Deposit date: | 2005-08-27 | Release date: | 2005-11-01 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Structural basis for inhibition of the insulin receptor by the adaptor protein grb14. Mol.Cell, 20, 2005
|
|