6HZ0
 
 | | THE GLIC PENTAMERIC LIGAND-GATED ION CHANNEL MUTANT K248A | | Descriptor: | ACETATE ION, CHLORIDE ION, DIUNDECYL PHOSPHATIDYL CHOLINE, ... | | Authors: | Hu, H.D, Delarue, M. | | Deposit date: | 2018-10-22 | | Release date: | 2018-12-19 | | Last modified: | 2024-05-15 | | Method: | X-RAY DIFFRACTION (2.75 Å) | | Cite: | Electrostatics, proton sensor, and networks governing the gating transition in GLIC, a proton-gated pentameric ion channel.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
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6HZW
 | | THE GLIC PENTAMERIC LIGAND-GATED ION CHANNEL 2.22 resolution | | Descriptor: | ACETATE ION, CHLORIDE ION, DIUNDECYL PHOSPHATIDYL CHOLINE, ... | | Authors: | Hu, H.D, Delarue, M. | | Deposit date: | 2018-10-24 | | Release date: | 2018-12-19 | | Last modified: | 2024-05-15 | | Method: | X-RAY DIFFRACTION (2.22 Å) | | Cite: | Electrostatics, proton sensor, and networks governing the gating transition in GLIC, a proton-gated pentameric ion channel.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
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6HYR
 | | THE GLIC PENTAMERIC LIGAND-GATED ION CHANNEL MUTANT Q193C+MMTS | | Descriptor: | DODECYL-BETA-D-MALTOSIDE, Proton-gated ion channel | | Authors: | Hu, H.D, Delarue, M. | | Deposit date: | 2018-10-22 | | Release date: | 2018-12-19 | | Last modified: | 2019-01-23 | | Method: | X-RAY DIFFRACTION (3.5 Å) | | Cite: | Electrostatics, proton sensor, and networks governing the gating transition in GLIC, a proton-gated pentameric ion channel.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
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6IP4
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8HIM
 | | A cryo-EM structure of B. oleracea RNA polymerase V elongation complex at 2.73 Angstrom | | Descriptor: | DNA (34-MER), DNA-directed RNA polymerase IV and V subunit 2, DNA-directed RNA polymerase V largest subunit, ... | | Authors: | Hu, H, Xie, G, Du, X, Du, J. | | Deposit date: | 2022-11-21 | | Release date: | 2023-03-22 | | Last modified: | 2024-07-03 | | Method: | ELECTRON MICROSCOPY (2.8 Å) | | Cite: | Structure and mechanism of the plant RNA polymerase V.
Science, 379, 2023
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7ET4
 | | Crystal structure of Arabidopsis TEM1 AP2 domain | | Descriptor: | AP2/ERF and B3 domain-containing transcription repressor TEM1, DNA (12-mer) | | Authors: | Hu, H, Du, J. | | Deposit date: | 2021-05-12 | | Release date: | 2021-09-15 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (2.7 Å) | | Cite: | TEM1 combinatorially binds to FLOWERING LOCUS T and recruits a Polycomb factor to repress the floral transition in Arabidopsis.
Proc.Natl.Acad.Sci.USA, 118, 2021
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6IP0
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7XMV
 | | E.coli phosphoribosylpyrophosphate (PRPP) synthetase type A(AMP/ADP) filament bound with ADP, AMP and R5P | | Descriptor: | 5-O-phosphono-alpha-D-ribofuranose, ADENOSINE MONOPHOSPHATE, ADENOSINE-5'-DIPHOSPHATE, ... | | Authors: | Hu, H.H, Lu, G.M, Chang, C.C, Liu, J.L. | | Deposit date: | 2022-04-27 | | Release date: | 2022-06-29 | | Last modified: | 2024-07-03 | | Method: | ELECTRON MICROSCOPY (2.6 Å) | | Cite: | Filamentation modulates allosteric regulation of PRPS.
Elife, 11, 2022
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7XN3
 | | E.coli phosphoribosylpyrophosphate (PRPP) synthetase type B filament bound with Pi | | Descriptor: | PHOSPHATE ION, Ribose-phosphate pyrophosphokinase | | Authors: | Hu, H.H, Lu, G.M, Chang, C.C, Liu, J.L. | | Deposit date: | 2022-04-27 | | Release date: | 2022-06-29 | | Last modified: | 2024-07-03 | | Method: | ELECTRON MICROSCOPY (2.9 Å) | | Cite: | Filamentation modulates allosteric regulation of PRPS.
Elife, 11, 2022
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7XMU
 | | E.coli phosphoribosylpyrophosphate (PRPP) synthetase type A filament bound with ADP, Pi and R5P | | Descriptor: | 5-O-phosphono-alpha-D-ribofuranose, ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ... | | Authors: | Hu, H.H, Lu, G.M, Chang, C.C, Liu, J.L. | | Deposit date: | 2022-04-26 | | Release date: | 2022-06-29 | | Last modified: | 2024-07-03 | | Method: | ELECTRON MICROSCOPY (2.3 Å) | | Cite: | Filamentation modulates allosteric regulation of PRPS.
Elife, 11, 2022
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6J9B
 | | Arabidopsis FUS3-DNA complex | | Descriptor: | B3 domain-containing transcription factor FUS3, DNA (5'-D(*AP*AP*TP*CP*CP*AP*TP*GP*CP*AP*GP*AP*AP*TP*C)-3'), DNA (5'-D(*AP*TP*TP*CP*TP*GP*CP*AP*TP*GP*GP*AP*TP*TP*G)-3') | | Authors: | Hu, H, Du, J. | | Deposit date: | 2019-01-22 | | Release date: | 2019-05-29 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | Embryonic resetting of the parental vernalized state by two B3 domain transcription factors in Arabidopsis.
Nat.Plants, 5, 2019
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7DME
 | | Solution structure of human Aha1 | | Descriptor: | Activator of 90 kDa heat shock protein ATPase homolog 1 | | Authors: | Hu, H, Zhou, C, Zhang, N. | | Deposit date: | 2020-12-03 | | Release date: | 2021-04-21 | | Last modified: | 2024-05-15 | | Method: | SOLUTION NMR | | Cite: | Aha1 Exhibits Distinctive Dynamics Behavior and Chaperone-Like Activity.
Molecules, 26, 2021
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7DMD
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7CFD
 | | Drosophila melanogaster Krimper eTud2-AubR15me2 complex | | Descriptor: | FI20010p1, Protein aubergine | | Authors: | Hu, H, Li, S. | | Deposit date: | 2020-06-25 | | Release date: | 2021-06-02 | | Last modified: | 2021-09-15 | | Method: | X-RAY DIFFRACTION (2.704 Å) | | Cite: | Binding of guide piRNA triggers methylation of the unstructured N-terminal region of Aub leading to assembly of the piRNA amplification complex.
Nat Commun, 12, 2021
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7CFC
 | | Drosophila melanogaster Krimper eTud1-Ago3 complex | | Descriptor: | FI20010p1, Protein argonaute-3 | | Authors: | Hu, H, Li, S. | | Deposit date: | 2020-06-25 | | Release date: | 2021-06-02 | | Last modified: | 2024-05-29 | | Method: | X-RAY DIFFRACTION (2.4 Å) | | Cite: | Binding of guide piRNA triggers methylation of the unstructured N-terminal region of Aub leading to assembly of the piRNA amplification complex.
Nat Commun, 12, 2021
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6J9A
 | | Crystal structure of Arabidopsis thaliana VAL1 in complex with FLC DNA fragment | | Descriptor: | B3 domain-containing transcription repressor VAL1, DNA (5'-D(*AP*AP*TP*CP*CP*AP*TP*GP*CP*AP*GP*AP*AP*TP*C)-3'), DNA (5'-D(*AP*TP*TP*CP*TP*GP*CP*AP*TP*GP*GP*AP*TP*TP*G)-3') | | Authors: | Hu, H, Du, J. | | Deposit date: | 2019-01-22 | | Release date: | 2019-05-29 | | Method: | X-RAY DIFFRACTION (2.915 Å) | | Cite: | Embryonic resetting of the parental vernalized state by two B3 domain transcription factors in Arabidopsis.
Nat.Plants, 5, 2019
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6J9C
 | | Crystal structure of Arabidopsis thaliana transcription factor LEC2-DNA complex | | Descriptor: | B3 domain-containing transcription factor LEC2, DNA (5'-D(*CP*AP*AP*TP*CP*CP*AP*TP*GP*CP*AP*GP*AP*AP*T)-3'), DNA (5'-D(*GP*AP*TP*TP*CP*TP*GP*CP*AP*TP*GP*GP*AP*TP*T)-3') | | Authors: | Hu, H, Du, J. | | Deposit date: | 2019-01-22 | | Release date: | 2019-05-29 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (3.102 Å) | | Cite: | Embryonic resetting of the parental vernalized state by two B3 domain transcription factors in Arabidopsis.
Nat.Plants, 5, 2019
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7ET6
 | | Crystal structure of Arabidopsis TEM1 B3-DNA complex | | Descriptor: | AP2/ERF and B3 domain-containing transcription repressor TEM1, FT-RY14-F, FT-RY14-R | | Authors: | Hu, H, Du, J. | | Deposit date: | 2021-05-12 | | Release date: | 2021-09-15 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (2.7 Å) | | Cite: | TEM1 combinatorially binds to FLOWERING LOCUS T and recruits a Polycomb factor to repress the floral transition in Arabidopsis.
Proc.Natl.Acad.Sci.USA, 118, 2021
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5NJY
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7CFB
 | | Drosophila melanogaster Krimper eTud1 apo structure | | Descriptor: | FI20010p1, SULFATE ION | | Authors: | Hu, H, Li, S. | | Deposit date: | 2020-06-25 | | Release date: | 2021-06-02 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | Binding of guide piRNA triggers methylation of the unstructured N-terminal region of Aub leading to assembly of the piRNA amplification complex.
Nat Commun, 12, 2021
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7ET5
 | | Crystal structure of Arabidopsis TEM1 AP2 domain | | Descriptor: | AP2/ERF and B3 domain-containing transcription repressor TEM1, SULFATE ION | | Authors: | Hu, H, Du, J. | | Deposit date: | 2021-05-12 | | Release date: | 2021-09-15 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (1.052 Å) | | Cite: | TEM1 combinatorially binds to FLOWERING LOCUS T and recruits a Polycomb factor to repress the floral transition in Arabidopsis.
Proc.Natl.Acad.Sci.USA, 118, 2021
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5X4F
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6OYA
 | | Structure of the Rhodopsin-Transducin-Nanobody Complex | | Descriptor: | Camelid antibody VHH fragment, Gt-alpha/Gi1-alpha chimera, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... | | Authors: | Gao, Y, Hu, H, Ramachandran, S, Erickson, J.W, Cerione, R.A, Skiniotis, G. | | Deposit date: | 2019-05-14 | | Release date: | 2019-07-24 | | Last modified: | 2019-12-04 | | Method: | ELECTRON MICROSCOPY (3.3 Å) | | Cite: | Structures of the Rhodopsin-Transducin Complex: Insights into G-Protein Activation.
Mol.Cell, 75, 2019
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6U1N
 | | GPCR-Beta arrestin structure in lipid bilayer | | Descriptor: | 3-amino-5-chloro-N-cyclopropyl-4-methyl-6-[2-(4-methylpiperazin-1-yl)-2-oxoethoxy]thieno[2,3-b]pyridine-2-carboxamide, Beta-arrestin-1, Fab30 heavy chain, ... | | Authors: | Staus, D.P, Hu, H, Robertson, M.J, Kleinhenz, A.L.W, Wingler, L.M, Capel, W.D, Latorraca, N.R, Lefkowitz, R.J, Skiniotis, G. | | Deposit date: | 2019-08-16 | | Release date: | 2020-02-26 | | Last modified: | 2020-03-25 | | Method: | ELECTRON MICROSCOPY (4 Å) | | Cite: | Structure of the M2 muscarinic receptor-beta-arrestin complex in a lipid nanodisc.
Nature, 579, 2020
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8XI3
 | | Structure of mouse SCMC-14-3-3gama complex | | Descriptor: | 14-3-3 protein gamma, NACHT, LRR and PYD domains-containing protein 5, ... | | Authors: | Chi, P, Han, Z, Jiao, H, Li, J, Wang, X, Hu, H, Deng, D. | | Deposit date: | 2023-12-19 | | Release date: | 2024-10-02 | | Method: | ELECTRON MICROSCOPY (3 Å) | | Cite: | Structure of mouse SCMC-14-3-3gama complex
To Be Published
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