8JYW
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8JYZ
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![BU of 8jyz by Molmil](/molmil-images/mine/8jyz) | Cryo-EM structure of RCD-1 pore from Neurospora crassa | Descriptor: | Gasdermin-like protein rcd-1-1, Gasdermin-like protein rcd-1-2 | Authors: | Hou, Y.J, Sun, Q, Li, Y, Ding, J. | Deposit date: | 2023-07-04 | Release date: | 2024-05-01 | Last modified: | 2024-05-29 | Method: | ELECTRON MICROSCOPY (3.63 Å) | Cite: | Cleavage-independent activation of ancient eukaryotic gasdermins and structural mechanisms. Science, 384, 2024
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8GTN
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5Y6G
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![BU of 5y6g by Molmil](/molmil-images/mine/5y6g) | PilZ domain with c-di-GMP of YcgR from Escherichia coli | Descriptor: | 9,9'-[(2R,3R,3aS,5S,7aR,9R,10R,10aS,12S,14aR)-3,5,10,12-tetrahydroxy-5,12-dioxidooctahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8]tetraoxadiphosphacyclododecine-2,9-diyl]bis(2-amino-1,9-dihydro-6H-purin-6-one), Flagellar brake protein YcgR, SULFATE ION | Authors: | Hou, Y.J, Wang, D.C, Li, D.F. | Deposit date: | 2017-08-11 | Release date: | 2018-07-18 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Structural insights into the mechanism of c-di-GMP-bound YcgR regulating flagellar motility inEscherichia coli. J.Biol.Chem., 295, 2020
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5Y6H
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5Y6F
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![BU of 5y6f by Molmil](/molmil-images/mine/5y6f) | Crystal structure of YcgR in complex with c-di-GMP from Escherichia coli | Descriptor: | 9,9'-[(2R,3R,3aS,5S,7aR,9R,10R,10aS,12S,14aR)-3,5,10,12-tetrahydroxy-5,12-dioxidooctahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8]tetraoxadiphosphacyclododecine-2,9-diyl]bis(2-amino-1,9-dihydro-6H-purin-6-one), Flagellar brake protein YcgR, SULFATE ION | Authors: | Hou, Y.J, Wang, D.C, Li, D.F. | Deposit date: | 2017-08-11 | Release date: | 2018-07-18 | Last modified: | 2024-03-27 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Structural insights into the mechanism of c-di-GMP-bound YcgR regulating flagellar motility inEscherichia coli. J.Biol.Chem., 295, 2020
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6XIR
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![BU of 6xir by Molmil](/molmil-images/mine/6xir) | Cryo-EM Structure of K63 Ubiquitinated Yeast Translocating Ribosome under Oxidative Stress | Descriptor: | 18S ribosomal RNA, 35S ribosomal RNA, 40S ribosomal protein S0-A, ... | Authors: | Zhou, Y, Bartesaghi, A, Silva, G.M. | Deposit date: | 2020-06-21 | Release date: | 2020-08-26 | Last modified: | 2020-09-23 | Method: | ELECTRON MICROSCOPY (3.2 Å) | Cite: | Structural impact of K63 ubiquitin on yeast translocating ribosomes under oxidative stress. Proc.Natl.Acad.Sci.USA, 117, 2020
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6XIQ
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![BU of 6xiq by Molmil](/molmil-images/mine/6xiq) | Cryo-EM Structure of K63R Ubiquitin Mutant Ribosome under Oxidative Stress | Descriptor: | 18S ribosomal RNA, 35S ribosomal RNA, 40S ribosomal protein S0-A, ... | Authors: | Zhou, Y, Bartesaghi, A, Silva, G.M. | Deposit date: | 2020-06-21 | Release date: | 2020-08-26 | Last modified: | 2020-09-23 | Method: | ELECTRON MICROSCOPY (4.2 Å) | Cite: | Structural impact of K63 ubiquitin on yeast translocating ribosomes under oxidative stress. Proc.Natl.Acad.Sci.USA, 117, 2020
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7WR0
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![BU of 7wr0 by Molmil](/molmil-images/mine/7wr0) | P32 of caspase-4 C258A mutant | Descriptor: | Caspase-4 | Authors: | Hou, Y.J, Zeng, H, Shao, F, Ding, J. | Deposit date: | 2022-01-26 | Release date: | 2023-01-25 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Structural mechanisms of calmodulin activation of Shigella effector OspC3 to ADP-riboxanate caspase-4/11 and block pyroptosis. Nat.Struct.Mol.Biol., 30, 2023
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7WR4
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![BU of 7wr4 by Molmil](/molmil-images/mine/7wr4) | Crystal structure of OspC3-calmodulin-caspase-4 complex | Descriptor: | Calmodulin-1, Caspase-4, OspC3 | Authors: | Hou, Y.J, Zeng, H, Shao, F, Ding, J. | Deposit date: | 2022-01-26 | Release date: | 2023-01-25 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.75 Å) | Cite: | Structural mechanisms of calmodulin activation of Shigella effector OspC3 to ADP-riboxanate caspase-4/11 and block pyroptosis. Nat.Struct.Mol.Biol., 30, 2023
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7WR2
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7WR6
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![BU of 7wr6 by Molmil](/molmil-images/mine/7wr6) | Crystal structure of ADP-riboxanated caspase-4 in complex with Af1521 | Descriptor: | ADP-ribose glycohydrolase AF_1521, Caspase-4, [[(3~{a}~{S},5~{R},6~{R},6~{a}~{R})-2-azanylidene-3-[(4~{R})-4-azanyl-5-oxidanylidene-pentyl]-6-oxidanyl-3~{a},5,6,6~{a}-tetrahydrofuro[2,3-d][1,3]oxazol-5-yl]methoxy-oxidanyl-phosphoryl] [(2~{R},3~{S},4~{R},5~{R})-5-(6-aminopurin-9-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methyl hydrogen phosphate | Authors: | Hou, Y.J, Zeng, H, Shao, F, Ding, J. | Deposit date: | 2022-01-26 | Release date: | 2023-01-25 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.96 Å) | Cite: | Structural mechanisms of calmodulin activation of Shigella effector OspC3 to ADP-riboxanate caspase-4/11 and block pyroptosis. Nat.Struct.Mol.Biol., 30, 2023
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7WR1
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![BU of 7wr1 by Molmil](/molmil-images/mine/7wr1) | P32 of caspase-4 C258A mutant in complex with OspC3 C-terminal ankyrin-repeat domain | Descriptor: | Caspase-4, OspC3 | Authors: | Hou, Y.J, Zeng, H, Shao, F, Ding, J. | Deposit date: | 2022-01-26 | Release date: | 2023-01-25 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.13 Å) | Cite: | Structural mechanisms of calmodulin activation of Shigella effector OspC3 to ADP-riboxanate caspase-4/11 and block pyroptosis. Nat.Struct.Mol.Biol., 30, 2023
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7WR3
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![BU of 7wr3 by Molmil](/molmil-images/mine/7wr3) | Crystal structure of MBP-fused OspC3 in complex with calmodulin | Descriptor: | Calmodulin-1, MBP-fused OspC3, NICOTINAMIDE, ... | Authors: | Hou, Y.J, Zeng, H, Shao, F, Ding, J. | Deposit date: | 2022-01-26 | Release date: | 2023-01-25 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.87 Å) | Cite: | Structural mechanisms of calmodulin activation of Shigella effector OspC3 to ADP-riboxanate caspase-4/11 and block pyroptosis. Nat.Struct.Mol.Biol., 30, 2023
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7WR5
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![BU of 7wr5 by Molmil](/molmil-images/mine/7wr5) | Crystal structure of OspC3-calmodulin-caspase-4 complex binding with 2'-aF-NAD+ | Descriptor: | Calmodulin-1, Caspase-4, OspC3, ... | Authors: | Hou, Y.J, Zeng, H, Shao, F, Ding, J. | Deposit date: | 2022-01-26 | Release date: | 2023-01-25 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (3.1 Å) | Cite: | Structural mechanisms of calmodulin activation of Shigella effector OspC3 to ADP-riboxanate caspase-4/11 and block pyroptosis. Nat.Struct.Mol.Biol., 30, 2023
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3W53
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6HRK
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![BU of 6hrk by Molmil](/molmil-images/mine/6hrk) | Structure of a far-red fluorescent biliprotein derived from a far-red induced allophycocyanin F subunit from a thermophilic cyanobacterium Chroococcidiopsis thermalis | Descriptor: | Allophycocyanin beta-18 subunit apoprotein, BILIVERDINE IX ALPHA | Authors: | Hou, Y.-N, Hoeppner, A, Ding, W.-L, Gaertner, W, Zhao, K.-H. | Deposit date: | 2018-09-27 | Release date: | 2019-10-09 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (2.52 Å) | Cite: | Control of a far-red/near-infrared spectral switch in an artificial fluorescent biliprotein derived from allophycocyanin Protein Sci., Suppl.: Diskette Appendix To V. , No. , [Month], Filename:, 31, 2022
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6J4C
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![BU of 6j4c by Molmil](/molmil-images/mine/6j4c) | Crystal structure of MarH, an epimerase for biosynthesis of Maremycins in Streptomyces, under 10 mM ZnSO4 | Descriptor: | ACETIC ACID, Cupin superfamily protein, GLYCEROL, ... | Authors: | Hou, Y, Liu, B, Hu, K, Zhang, R. | Deposit date: | 2019-01-08 | Release date: | 2020-01-15 | Last modified: | 2024-03-27 | Method: | X-RAY DIFFRACTION (1.58 Å) | Cite: | Structural basis of the mechanism of beta-methyl epimerization by enzyme MarH. Org.Biomol.Chem., 17, 2019
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6J4D
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![BU of 6j4d by Molmil](/molmil-images/mine/6j4d) | Crystal structure of MarH, an epimerase for biosynthesis of Maremycins in Streptomyces, under pH 4.7, without Zn | Descriptor: | CITRATE ANION, Cupin superfamily protein, GLYCEROL | Authors: | Hou, Y, Liu, B, Hu, K, Zhang, R. | Deposit date: | 2019-01-08 | Release date: | 2020-01-15 | Last modified: | 2024-03-27 | Method: | X-RAY DIFFRACTION (1.4 Å) | Cite: | Structural Basis for the Isomerization Mechanism of MarH To Be Published
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6J4B
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![BU of 6j4b by Molmil](/molmil-images/mine/6j4b) | Crystal structure of MarH, an epimerase for biosynthesis of Maremycins in Streptomyces, under 400 mM Zinc acetate | Descriptor: | ACETIC ACID, Cupin superfamily protein, GLYCEROL, ... | Authors: | Hou, Y, Liu, B, Hu, K, Zhang, R. | Deposit date: | 2019-01-08 | Release date: | 2020-01-15 | Last modified: | 2024-03-27 | Method: | X-RAY DIFFRACTION (1.58 Å) | Cite: | Structural basis of the mechanism of beta-methyl epimerization by enzyme MarH. Org.Biomol.Chem., 17, 2019
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7YRZ
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![BU of 7yrz by Molmil](/molmil-images/mine/7yrz) | Crystal structure of HCoV 229E main protease in complex with PF07321332 | Descriptor: | (1R,2S,5S)-N-{(1E,2S)-1-imino-3-[(3S)-2-oxopyrrolidin-3-yl]propan-2-yl}-6,6-dimethyl-3-[3-methyl-N-(trifluoroacetyl)-L-valyl]-3-azabicyclo[3.1.0]hexane-2-carboxamide, 3C-like proteinase | Authors: | Zhou, Y.R, Zeng, P, Zhou, X.L, Lin, C, Zhang, J, Yin, X.S, Li, J. | Deposit date: | 2022-08-11 | Release date: | 2023-08-16 | Last modified: | 2024-03-06 | Method: | X-RAY DIFFRACTION (1.79 Å) | Cite: | Structural basis of main proteases of HCoV-229E bound to inhibitor PF-07304814 and PF-07321332. Biochem.Biophys.Res.Commun., 657, 2023
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7DAI
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![BU of 7dai by Molmil](/molmil-images/mine/7dai) | The crystal structure of a serotonin N-acetyltransferase from Oryza Sativa | Descriptor: | Serotonin N-acetyltransferase 1, chloroplastic | Authors: | Zhou, Y.Z, Liao, L.J, Tang, T, Guo, Y, Liu, X.K, Liu, B, Zhao, Y.C. | Deposit date: | 2020-10-16 | Release date: | 2021-09-22 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Structural and Molecular Dynamics Analysis of Plant Serotonin N-Acetyltransferase Reveal an Acid/Base-Assisted Catalysis in Melatonin Biosynthesis. Angew.Chem.Int.Ed.Engl., 60, 2021
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7DAJ
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![BU of 7daj by Molmil](/molmil-images/mine/7daj) | The crystal structure of serotonin N-acetyltransferase in complex with acetyl-CoA from Oryza Sativa | Descriptor: | ACETYL COENZYME *A, Serotonin N-acetyltransferase 1, chloroplastic | Authors: | Zhou, Y.Z, Liao, L.J, Tang, T, Guo, Y, Liu, X.K, Liu, B, Zhao, Y.C. | Deposit date: | 2020-10-16 | Release date: | 2021-09-22 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Structural and Molecular Dynamics Analysis of Plant Serotonin N-Acetyltransferase Reveal an Acid/Base-Assisted Catalysis in Melatonin Biosynthesis. Angew.Chem.Int.Ed.Engl., 60, 2021
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7DAL
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![BU of 7dal by Molmil](/molmil-images/mine/7dal) | The crystal structure of a serotonin N-acetyltransferase in complex with serotonin and acetyl-CoA from Oryza Sativa | Descriptor: | ACETYL COENZYME *A, SEROTONIN, Serotonin N-acetyltransferase 1, ... | Authors: | Zhou, Y.Z, Liao, L.J, Tang, T, Guo, Y, Liu, X.K, Liu, B, Zhao, Y.C. | Deposit date: | 2020-10-16 | Release date: | 2021-09-22 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Structural and Molecular Dynamics Analysis of Plant Serotonin N-Acetyltransferase Reveal an Acid/Base-Assisted Catalysis in Melatonin Biosynthesis. Angew.Chem.Int.Ed.Engl., 60, 2021
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7DAK
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![BU of 7dak by Molmil](/molmil-images/mine/7dak) | The crystal structure of a serotonin N-acetyltransferase in complex with 5-Methoxytryptamine and acetyl-CoA from Oryza Sativa | Descriptor: | 2-(5-methoxy-1H-indol-3-yl)ethanamine, ACETYL COENZYME *A, Serotonin N-acetyltransferase 1, ... | Authors: | Zhou, Y.Z, Liao, L.J, Tang, T, Guo, Y, Liu, X.K, Liu, B, Zhao, Y.C. | Deposit date: | 2020-10-16 | Release date: | 2021-09-22 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Structural and Molecular Dynamics Analysis of Plant Serotonin N-Acetyltransferase Reveal an Acid/Base-Assisted Catalysis in Melatonin Biosynthesis. Angew.Chem.Int.Ed.Engl., 60, 2021
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