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PDB: 414 件

8D84
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E. faecium MurAA in complex with UDP-N-acetylmuramic acid (UNAM) and a covalent adduct of PEP with Cys119
分子名称: (2R)-2-{[(2R,3R,4R,5S,6R)-3-(acetylamino)-2-{[(S)-{[(R)-{[(2R,3S,4R,5R)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-3,4-dihydroxytetrahydrofuran-2-yl]methoxy}(hydroxy)phosphoryl]oxy}(hydroxy)phosphoryl]oxy}-5-hydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-4-yl]oxy}propanoic acid, UDP-N-acetylglucosamine 1-carboxyvinyltransferase
著者Zhou, Y, Shamoo, Y.
登録日2022-06-07
公開日2023-07-05
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.65 Å)
主引用文献E. faecium MurAA in complex with fosfomycin and UNAG
To Be Published
7M42
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Complex of SARS-CoV-2 receptor binding domain with the Fab fragments of neutralizing antibodies REGN10985 and REGN10989
分子名称: REGN10985 antibody Fab fragment heavy chain, REGN10985 antibody Fab fragment light chain, REGN10989 antibody Fab fragment heavy chain, ...
著者Zhou, Y, Romero Hernandez, A, Saotome, K, Franklin, M.C.
登録日2021-03-19
公開日2021-07-28
最終更新日2021-08-25
実験手法ELECTRON MICROSCOPY (3.3 Å)
主引用文献The monoclonal antibody combination REGEN-COV protects against SARS-CoV-2 mutational escape in preclinical and human studies.
Cell, 184, 2021
5I85
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aSMase with zinc and phosphocholine
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, PHOSPHOCHOLINE, ...
著者Zhou, Y.F, Wei, R.R.
登録日2016-02-18
公開日2016-09-07
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Human acid sphingomyelinase structures provide insight to molecular basis of Niemann-Pick disease.
Nat Commun, 7, 2016
5I81
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aSMase with zinc
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, SULFATE ION, ...
著者Zhou, Y.F, Wei, R.R.
登録日2016-02-18
公開日2016-09-07
最終更新日2021-03-24
実験手法X-RAY DIFFRACTION (2.25 Å)
主引用文献Human acid sphingomyelinase structures provide insight to molecular basis of Niemann-Pick disease.
Nat Commun, 7, 2016
8GUL
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BU of 8gul by Molmil
Chitin-active AA10 LPMO (GbpA) complexed with Cu(II) from Vibrio campbellii
分子名称: COPPER (II) ION, GlcNAc-binding protein A, SULFATE ION
著者Zhou, Y, Robinson, R.C, Suginta, W.
登録日2022-09-12
公開日2023-06-21
実験手法X-RAY DIFFRACTION (2.44 Å)
主引用文献Structural and binding studies of a new chitin-active AA10 lytic polysaccharide monooxygenase from the marine bacterium Vibrio campbellii.
Acta Crystallogr D Struct Biol, 79, 2023
8GUM
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BU of 8gum by Molmil
Chitin-active AA10 LPMO (GbpA) from Vibrio campbellii
分子名称: GlcNAc-binding protein A
著者Zhou, Y, Robinson, R.C, Suginta, W.
登録日2022-09-12
公開日2023-06-21
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.35 Å)
主引用文献Structural and binding studies of a new chitin-active AA10 lytic polysaccharide monooxygenase from the marine bacterium Vibrio campbellii.
Acta Crystallogr D Struct Biol, 79, 2023
8CYR
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BU of 8cyr by Molmil
Alpha-synuclein fibril from spontaneous control
分子名称: Alpha-synuclein
著者Zhou, Y, Sokratian, A, Xu, E, Viverette, E, Dillard, L, Yuan, Y, Li, J.Y, Matarangas, A, Bouvette, J, Borgnia, M, Bartesaghi, A, West, A.
登録日2022-05-24
公開日2023-05-31
最終更新日2024-06-12
実験手法ELECTRON MICROSCOPY (4.2 Å)
主引用文献Distinct cryo-EM structures and functions of alpha-synuclein fibrils amplified from cerebrospinal fluid
To Be Published
5I8R
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BU of 5i8r by Molmil
aSMase with zinc
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Sphingomyelin phosphodiesterase, ...
著者Zhou, Y.F, Wei, R.R.
登録日2016-02-19
公開日2016-09-07
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (3.646 Å)
主引用文献Human acid sphingomyelinase structures provide insight to molecular basis of Niemann-Pick disease.
Nat Commun, 7, 2016
8D82
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BU of 8d82 by Molmil
Cryo-EM structure of human IL-6 signaling complex in detergent: model containing full extracellular domains
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Interleukin-6, ...
著者Zhou, Y, Franklin, M.C.
登録日2022-06-07
公開日2023-03-29
実験手法ELECTRON MICROSCOPY (3.22 Å)
主引用文献Structural insights into the assembly of gp130 family cytokine signaling complexes.
Sci Adv, 9, 2023
8D74
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BU of 8d74 by Molmil
Cryo-EM structure of human CNTF signaling complex: model containing the interaction core region
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Ciliary neurotrophic factor, ...
著者Zhou, Y, Franklin, M.C.
登録日2022-06-07
公開日2023-03-29
実験手法ELECTRON MICROSCOPY (3.03 Å)
主引用文献Structural insights into the assembly of gp130 family cytokine signaling complexes.
Sci Adv, 9, 2023
8D7R
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BU of 8d7r by Molmil
Cryo-EM structure of human CLCF1 signaling complex: model containing the interaction core region
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Cardiotrophin-like cytokine factor 1, ...
著者Zhou, Y, Franklin, M.C.
登録日2022-06-07
公開日2023-03-29
実験手法ELECTRON MICROSCOPY (3.9 Å)
主引用文献Structural insights into the assembly of gp130 family cytokine signaling complexes.
Sci Adv, 9, 2023
8D7E
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BU of 8d7e by Molmil
Cryo-EM structure of human CNTFR alpha in complex with the Fab fragments of two antibodies
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Ciliary neurotrophic factor receptor subunit alpha, H4H25311P2 antibody Fab fragment heavy chain, ...
著者Zhou, Y, Franklin, M.C.
登録日2022-06-07
公開日2023-03-29
実験手法ELECTRON MICROSCOPY (2.93 Å)
主引用文献Structural insights into the assembly of gp130 family cytokine signaling complexes.
Sci Adv, 9, 2023
8D6A
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BU of 8d6a by Molmil
Cryo-EM structure of human LIF signaling complex: model containing the interaction core region
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Interleukin-6 receptor subunit beta, ...
著者Zhou, Y, Franklin, M.C.
登録日2022-06-06
公開日2023-03-29
実験手法ELECTRON MICROSCOPY (3.54 Å)
主引用文献Structural insights into the assembly of gp130 family cytokine signaling complexes.
Sci Adv, 9, 2023
8D7H
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BU of 8d7h by Molmil
Cryo-EM structure of human CLCF1 in complex with CRLF1 and CNTFR alpha
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Cardiotrophin-like cytokine factor 1, ...
著者Zhou, Y, Franklin, M.C.
登録日2022-06-07
公開日2023-03-29
実験手法ELECTRON MICROSCOPY (3.4 Å)
主引用文献Structural insights into the assembly of gp130 family cytokine signaling complexes.
Sci Adv, 9, 2023
8D85
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BU of 8d85 by Molmil
Cryo-EM structure of human IL-27 signaling complex: model containing the interaction core region
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Interleukin-27 receptor subunit alpha, ...
著者Zhou, Y, Franklin, M.C.
登録日2022-06-07
公開日2023-03-29
実験手法ELECTRON MICROSCOPY (3.81 Å)
主引用文献Structural insights into the assembly of gp130 family cytokine signaling complexes.
Sci Adv, 9, 2023
5GUJ
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BU of 5guj by Molmil
Crystal structure of the Bacillus subtilis DnaG RNA Polymerase Domain, natural degradation of full length DnaG
分子名称: DNA primase
著者Zhou, Y, Liu, Z, Wang, G.
登録日2016-08-29
公開日2017-04-19
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Structural Insight into the Specific DNA Template Binding to DnaG primase in Bacteria
Sci Rep, 7, 2017
3E4O
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BU of 3e4o by Molmil
Crystal structure of succinate bound state DctB
分子名称: C4-dicarboxylate transport sensor protein dctB, MAGNESIUM ION, SUCCINIC ACID
著者Zhou, Y.F, Nan, J, Nan, B.Y, Liang, Y.H, Panjikar, S, Su, X.D.
登録日2008-08-12
公開日2008-10-21
最終更新日2017-10-25
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献C4-dicarboxylates sensing mechanism revealed by the crystal structures of DctB sensor domain.
J.Mol.Biol., 383, 2008
3E4Q
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BU of 3e4q by Molmil
Crystal structure of apo DctB
分子名称: C4-dicarboxylate transport sensor protein dctB, CALCIUM ION
著者Zhou, Y.F, Nan, J, Nan, B.Y, Liang, Y.H, Panjikar, S, Su, X.D.
登録日2008-08-12
公開日2008-10-21
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.75 Å)
主引用文献C4-dicarboxylates sensing mechanism revealed by the crystal structures of DctB sensor domain.
J.Mol.Biol., 383, 2008
3E4P
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BU of 3e4p by Molmil
Crystal structure of malonate occupied DctB
分子名称: C4-dicarboxylate transport sensor protein dctB, MALONIC ACID, STRONTIUM ION
著者Zhou, Y.F, Nan, J, Nan, B.Y, Liang, Y.H, Panjikar, S, Su, X.D.
登録日2008-08-12
公開日2008-10-21
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献C4-dicarboxylates sensing mechanism revealed by the crystal structures of DctB sensor domain.
J.Mol.Biol., 383, 2008
2ZBB
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BU of 2zbb by Molmil
P43 crystal of DctBp
分子名称: C4-dicarboxylate transport sensor protein dctB, MALONIC ACID
著者Zhou, Y.F, Nan, B.Y, Liu, X, Nan, J, Liang, Y.H, Panjikar, S, Ma, Q.J, Wang, Y.P, Su, X.-D.
登録日2007-10-18
公開日2008-11-18
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献crystal structures of sensory histidine kinase DctBp
to be published
5XOH
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BU of 5xoh by Molmil
Crystal structure of bergaptol o-methyltransferase complex
分子名称: 4-oxidanylfuro[3,2-g]chromen-7-one, Bergaptol O-methyltransferase, S-ADENOSYL-L-HOMOCYSTEINE
著者Zhou, Y, Zeng, Z.
登録日2017-05-28
公開日2018-05-23
最終更新日2024-03-27
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Crystal structure of bergaptol o-methyltransferase complex
To Be Published
3O19
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BU of 3o19 by Molmil
Structure-function analysis of human L-Prostaglandin D Synthase bound with fatty acid
分子名称: OLEIC ACID, PALMITIC ACID, Prostaglandin-H2 D-isomerase
著者Zhou, Y, Shaw, N, Li, Y, Zhao, Y, Zhang, R, Liu, Z.-J.
登録日2010-07-21
公開日2010-09-22
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (1.66 Å)
主引用文献Structure-function analysis of human L-Prostaglandin D Synthase bound with fatty acid
To be Published
3O2Y
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BU of 3o2y by Molmil
Structure-function analysis of human L-Prostaglandin D Synthase bound with fatty acid
分子名称: GLYCEROL, OLEIC ACID, PALMITIC ACID, ...
著者Zhou, Y, Shaw, N, Li, Y, Zhao, Y, Zhang, R, Liu, Z.-J.
登録日2010-07-23
公開日2010-09-22
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Structure-function analysis of human L-Prostaglandin D Synthase bound with fatty acid
To be Published
6K5M
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BU of 6k5m by Molmil
The crystal structure of a serotonin N-acetyltransferase from Oryza Sativa (Rice)
分子名称: Serotonin N-acetyltransferase 1, chloroplastic
著者Zhou, Y.Z, Liao, L.J, Liu, X.K, Guo, Y, Zhao, Y.C, Zeng, Z.X.
登録日2019-05-29
公開日2020-06-03
最終更新日2021-09-22
実験手法X-RAY DIFFRACTION (1.793 Å)
主引用文献Structural and Molecular Dynamics Analysis of Plant Serotonin N-Acetyltransferase Reveal an Acid/Base-Assisted Catalysis in Melatonin Biosynthesis.
Angew.Chem.Int.Ed.Engl., 60, 2021
6KHP
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BU of 6khp by Molmil
Crystal structure of Oryza sativa TDC with PLP and tryptamine
分子名称: 2-(1H-INDOL-3-YL)ETHANAMINE, ACETATE ION, CALCIUM ION, ...
著者Zhou, Y.Z, Liao, L.J, Liu, X.K, Guo, Y, Zhao, Y.C, Zeng, Z.X.
登録日2019-07-16
公開日2020-07-15
実験手法X-RAY DIFFRACTION (2.299 Å)
主引用文献Crystal structure ofOryza sativaTDC reveals the substrate specificity for TDC-mediated melatonin biosynthesis.
J Adv Res, 24, 2020

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件を2024-07-17に公開中

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