6DJM
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![BU of 6djm by Molmil](/molmil-images/mine/6djm) | Cryo-EM structure of AMPPNP-actin filaments | Descriptor: | Actin, alpha skeletal muscle, MAGNESIUM ION, ... | Authors: | Chou, S.Z, Pollard, T.D. | Deposit date: | 2018-05-25 | Release date: | 2019-02-27 | Last modified: | 2020-01-08 | Method: | ELECTRON MICROSCOPY (3.1 Å) | Cite: | Mechanism of actin polymerization revealed by cryo-EM structures of actin filaments with three different bound nucleotides. Proc.Natl.Acad.Sci.USA, 116, 2019
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6DJN
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![BU of 6djn by Molmil](/molmil-images/mine/6djn) | Cryo-EM structure of ADP-Pi-actin filaments | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Actin, alpha skeletal muscle, ... | Authors: | Chou, S.Z, Pollard, T.D. | Deposit date: | 2018-05-25 | Release date: | 2019-02-27 | Last modified: | 2020-01-08 | Method: | ELECTRON MICROSCOPY (3.1 Å) | Cite: | Mechanism of actin polymerization revealed by cryo-EM structures of actin filaments with three different bound nucleotides. Proc.Natl.Acad.Sci.USA, 116, 2019
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2WYG
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![BU of 2wyg by Molmil](/molmil-images/mine/2wyg) | Structure and property based design of factor Xa inhibitors: pyrrolidin-2-ones with monoaryl P4 motifs | Descriptor: | (E)-2-(5-CHLOROTHIOPHEN-2-YL)-N-[(3S)-1-{4-[(1R)-1-(DIMETHYLAMINO)ETHYL]-2-FLUOROPHENYL}-2-OXOPYRROLIDIN-3-YL]ETHENESULFONAMIDE, ACTIVATED FACTOR XA HEAVY CHAIN, FACTOR X LIGHT CHAIN | Authors: | Kleanthous, S, Borthwick, A.D, Brown, D, Burns-Kurtis, C.L, Campbell, M, Chaudry, L, Chan, C, Clarte, M, Convery, M.A, Harling, J.D, Hortense, E, Irving, W.R, Irvine, S, Pateman, A.J, Patikis, A, Pinto, I.L, Pollard, D.R, Roethka, T.J, Senger, S, Shah, G.P, Stelman, G.J, Toomey, J.R, Watson, N.S, Whittaker, C, Zhou, P, Young, R.J. | Deposit date: | 2009-11-16 | Release date: | 2010-12-01 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (1.88 Å) | Cite: | Structure and Property Based Design of Factor Xa Inhibitors: Pyrrolidin-2-Ones with Monoaryl P4 Motifs Bioorg.Med.Chem.Lett., 20, 2010
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2WYJ
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![BU of 2wyj by Molmil](/molmil-images/mine/2wyj) | Structure and property based design of factor Xa inhibitors: pyrrolidin-2-ones with monoaryl P4 motifs | Descriptor: | (E)-2-(5-CHLOROTHIOPHEN-2-YL)-N-[(3S)-1-{4-[(1S)-1-(DIMETHYLAMINO)ETHYL]-2-FLUOROPHENYL}-2-OXOPYRROLIDIN-3-YL]ETHENESULFONAMIDE, ACTIVATED FACTOR XA HEAVY CHAIN, FACTOR X LIGHT CHAIN | Authors: | Kleanthous, S, Borthwick, A.D, Brown, D, Burns-Kurtis, C.L, Campbell, M, Chaudry, L, Chan, C, Clarte, M, Convery, M.A, Harling, J.D, Hortense, E, Irving, W.R, Irvine, S, Pateman, A.J, Patikis, A, Pinto, I.L, Pollard, D.R, Roethka, T.J, Senger, S, Shah, G.P, Stelman, G.J, Toomey, J.R, Watson, N.S, Whittaker, C, Zhou, P, Young, R.J. | Deposit date: | 2009-11-16 | Release date: | 2010-12-01 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.38 Å) | Cite: | Structure and Property Based Design of Factor Xa Inhibitors: Pyrrolidin-2-Ones with Monoaryl P4 Motifs Bioorg.Med.Chem.Lett., 20, 2010
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8E9B
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![BU of 8e9b by Molmil](/molmil-images/mine/8e9b) | |
7K21
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![BU of 7k21 by Molmil](/molmil-images/mine/7k21) | |
7K20
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![BU of 7k20 by Molmil](/molmil-images/mine/7k20) | |
8DOA
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![BU of 8doa by Molmil](/molmil-images/mine/8doa) | |
3HYP
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![BU of 3hyp by Molmil](/molmil-images/mine/3hyp) | |
3HXS
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![BU of 3hxs by Molmil](/molmil-images/mine/3hxs) | Crystal Structure of Bacteroides fragilis TrxP | Descriptor: | Thioredoxin, ZINC ION | Authors: | Shouldice, S.R. | Deposit date: | 2009-06-22 | Release date: | 2010-01-12 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (1.996 Å) | Cite: | In vivo oxidative protein folding can be facilitated by oxidation-reduction cycling Mol.Microbiol., 75, 2010
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1Q35
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![BU of 1q35 by Molmil](/molmil-images/mine/1q35) | Crystal Structure of Pasteurella haemolytica Apo Ferric ion-Binding Protein A | Descriptor: | 1,2-ETHANEDIOL, FORMIC ACID, iron binding protein FbpA | Authors: | Shouldice, S.R, Dougan, D.R, Skene, R.J, Snell, G, Scheibe, D, Williams, P.A, Kirby, S, McRee, D.E, Schryvers, A.B, Tari, L.W. | Deposit date: | 2003-07-28 | Release date: | 2003-11-11 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (1.2 Å) | Cite: | Crystal structure of Pasteurella haemolytica ferric ion-binding protein A reveals a novel class of bacterial iron-binding proteins J.Biol.Chem., 278, 2003
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5UP1
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![BU of 5up1 by Molmil](/molmil-images/mine/5up1) | Solution structure of the de novo mini protein EEHEE_rd3_1049 | Descriptor: | EEHEE_rd3_1049 | Authors: | Houliston, S, Rocklin, G.J, Lemak, A, Carter, L, Chidyausiku, T.M, Baker, D, Arrowsmith, C.H. | Deposit date: | 2017-02-01 | Release date: | 2017-07-26 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | Global analysis of protein folding using massively parallel design, synthesis, and testing. Science, 357, 2017
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3KN7
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![BU of 3kn7 by Molmil](/molmil-images/mine/3kn7) | |
4F4M
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![BU of 4f4m by Molmil](/molmil-images/mine/4f4m) | |
4EOB
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![BU of 4eob by Molmil](/molmil-images/mine/4eob) | |
3KN8
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![BU of 3kn8 by Molmil](/molmil-images/mine/3kn8) | |
3M4U
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![BU of 3m4u by Molmil](/molmil-images/mine/3m4u) | |
5UOI
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![BU of 5uoi by Molmil](/molmil-images/mine/5uoi) | Solution structure of the de novo mini protein HHH_rd1_0142 | Descriptor: | HHH_rd1_0142 | Authors: | Houliston, S, Rocklin, G.J, Lemak, A, Carter, L, Chidyausiku, T.M, Baker, D, Arrowsmith, C.H. | Deposit date: | 2017-01-31 | Release date: | 2017-07-26 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | Global analysis of protein folding using massively parallel design, synthesis, and testing. Science, 357, 2017
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1NNF
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![BU of 1nnf by Molmil](/molmil-images/mine/1nnf) | Crystal Structure Analysis of Haemophlius Influenzae Ferric-ion Binding Protein H9Q Mutant Form | Descriptor: | FE (III) ION, Iron-utilization periplasmic protein, {[-(BIS-CARBOXYMETHYL-AMINO)-ETHYL]-CARBOXYMETHYL-AMINO}-ACETIC ACID | Authors: | Shouldice, S.R, Dougan, D.R, Skene, R.J, Tari, L.W, McRee, D.E, Yu, R.-H, Schryvers, A.B. | Deposit date: | 2003-01-13 | Release date: | 2003-04-01 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (1.1 Å) | Cite: | High Resolution Structure of an Alternate Form of the Ferric ion Binding Protein from Haemophilus influenzae J.Biol.Chem., 278, 2003
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5UP5
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![BU of 5up5 by Molmil](/molmil-images/mine/5up5) | Solution structure of the de novo mini protein EHEE_rd1_0284 | Descriptor: | EHEE_rd1_0284 | Authors: | Houliston, S, Rocklin, G.J, Lemak, A, Carter, L, Chidyausiku, T.M, Baker, D, Arrowsmith, C.H. | Deposit date: | 2017-02-01 | Release date: | 2017-07-26 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | Global analysis of protein folding using massively parallel design, synthesis, and testing. Science, 357, 2017
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3H93
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![BU of 3h93 by Molmil](/molmil-images/mine/3h93) | Crystal Structure of Pseudomonas aeruginosa DsbA | Descriptor: | GLYCEROL, Thiol:disulfide interchange protein dsbA | Authors: | Shouldice, S.R. | Deposit date: | 2009-04-29 | Release date: | 2009-12-08 | Last modified: | 2017-11-01 | Method: | X-RAY DIFFRACTION (1.501 Å) | Cite: | Characterization of the DsbA Oxidative Folding Catalyst from Pseudomonas aeruginosa Reveals a Highly Oxidizing Protein that Binds Small Molecules. Antioxid Redox Signal, 12, 2010
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1QVS
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![BU of 1qvs by Molmil](/molmil-images/mine/1qvs) | Crystal Structure of Haemophilus influenzae H9A mutant Holo Ferric ion-Binding Protein A | Descriptor: | FE (III) ION, Iron-utilization periplasmic protein, PHOSPHATE ION | Authors: | Shouldice, S.R, Skene, R.J, Dougan, D.R, McRee, D.E, Tari, L.W, Schryvers, A.B. | Deposit date: | 2003-08-28 | Release date: | 2003-11-04 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Presence of ferric hydroxide clusters in mutants of Haemophilus influenzae ferric ion-binding protein A Biochemistry, 42, 2003
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1QW0
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![BU of 1qw0 by Molmil](/molmil-images/mine/1qw0) | Crystal Structure of Haemophilus influenzae N175L mutant Holo Ferric ion-Binding Protein A | Descriptor: | FE (III) ION, Iron-utilization periplasmic protein, PHOSPHATE ION | Authors: | Shouldice, S.R, Skene, R.J, Dougan, D.R, McRee, D.E, Tari, L.W, Schryvers, A.B. | Deposit date: | 2003-08-29 | Release date: | 2003-11-04 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Presence of ferric hydroxide clusters in mutants of Haemophilus influenzae ferric ion-binding protein A Biochemistry, 42, 2003
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3CS4
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![BU of 3cs4 by Molmil](/molmil-images/mine/3cs4) | Structure-based design of a superagonist ligand for the vitamin D nuclear receptor | Descriptor: | (1S,3R,5Z,7E,14beta,17alpha)-17-[(2S,4S)-4-(2-hydroxy-2-methylpropyl)-2-methyltetrahydrofuran-2-yl]-9,10-secoandrosta-5,7,10-triene-1,3-diol, Vitamin D3 receptor | Authors: | Hourai, S, Rodriguez, L.C, Antony, P, Reina-San-Martin, B, Ciesielski, F, Magnier, B.C, Schoonjans, K, Mourino, A, Rochel, N, Moras, D. | Deposit date: | 2008-04-09 | Release date: | 2008-05-27 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Structure-based design of a superagonist ligand for the vitamin d nuclear receptor. Chem.Biol., 15, 2008
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1L1V
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![BU of 1l1v by Molmil](/molmil-images/mine/1l1v) | UNUSUAL ACTD/DNA_TA COMPLEX STRUCTURE | Descriptor: | 5'-D(*GP*TP*CP*AP*CP*CP*GP*AP*C)-3', ACTINOMYCIN D | Authors: | Chou, S.-H, Chin, K.-H, Chen, F.-M. | Deposit date: | 2002-02-20 | Release date: | 2002-03-06 | Last modified: | 2024-07-10 | Method: | SOLUTION NMR | Cite: | Looped Out and Perpendicular: Deformation of Watson-Crick Base Pair Associated with Actinomycin D Binding. Proc.Natl.Acad.Sci.USA, 99, 2002
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