1RFN
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1rfn by Molmil](/molmil-images/mine/1rfn) | HUMAN COAGULATION FACTOR IXA IN COMPLEX WITH P-AMINO BENZAMIDINE | Descriptor: | CALCIUM ION, P-AMINO BENZAMIDINE, PROTEIN (COAGULATION FACTOR IX), ... | Authors: | Hopfner, K.-P, Lang, A, Karcher, A, Sichler, K, Kopetzki, E, Brandstetter, H, Huber, R, Bode, W, Engh, R.A. | Deposit date: | 1999-04-19 | Release date: | 1999-09-01 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Coagulation factor IXa: the relaxed conformation of Tyr99 blocks substrate binding. Structure Fold.Des., 7, 1999
|
|
1TGO
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1tgo by Molmil](/molmil-images/mine/1tgo) | THERMOSTABLE B TYPE DNA POLYMERASE FROM THERMOCOCCUS GORGONARIUS | Descriptor: | PROTEIN (THERMOSTABLE B DNA POLYMERASE) | Authors: | Hopfner, K.-P, Eichinger, A, Engh, R.A, Laue, F, Ankenbauer, W, Huber, R, Angerer, B. | Deposit date: | 1999-02-23 | Release date: | 1999-03-22 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Crystal structure of a thermostable type B DNA polymerase from Thermococcus gorgonarius. Proc.Natl.Acad.Sci.USA, 96, 1999
|
|
1II8
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1ii8 by Molmil](/molmil-images/mine/1ii8) | Crystal structure of the P. furiosus Rad50 ATPase domain | Descriptor: | PHOSPHATE ION, Rad50 ABC-ATPase | Authors: | Hopfner, K.-P, Karcher, A, Craig, L, Woo, T.T, Carney, J.P, Tainer, J.A. | Deposit date: | 2001-04-20 | Release date: | 2001-05-30 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (3.02 Å) | Cite: | Structural biochemistry and interaction architecture of the DNA double-strand break repair Mre11 nuclease and Rad50-ATPase. Cell(Cambridge,Mass.), 105, 2001
|
|
1II7
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1ii7 by Molmil](/molmil-images/mine/1ii7) | Crystal structure of P. furiosus Mre11 with manganese and dAMP | Descriptor: | 2'-DEOXYADENOSINE-5'-MONOPHOSPHATE, MANGANESE (II) ION, Mre11 nuclease, ... | Authors: | Hopfner, K.-P, Karcher, A, Craig, L, Woo, T.T, Carney, J.P, Tainer, J.A. | Deposit date: | 2001-04-20 | Release date: | 2001-05-30 | Last modified: | 2024-05-29 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Structural biochemistry and interaction architecture of the DNA double-strand break repair Mre11 nuclease and Rad50-ATPase. Cell(Cambridge,Mass.), 105, 2001
|
|
3PP3
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3pp3 by Molmil](/molmil-images/mine/3pp3) | |
3PP4
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3pp4 by Molmil](/molmil-images/mine/3pp4) | |
4WVY
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4wvy by Molmil](/molmil-images/mine/4wvy) | |
3M7N
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3m7n by Molmil](/molmil-images/mine/3m7n) | |
5DA9
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5da9 by Molmil](/molmil-images/mine/5da9) | ATP-gamma-S bound Rad50 from Chaetomium thermophilum in complex with the Rad50-binding domain of Mre11 | Descriptor: | MAGNESIUM ION, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER, Putative double-strand break protein, ... | Authors: | Seifert, F.U, Lammens, K, Stoehr, G, Kessler, B, Hopfner, K.-P. | Deposit date: | 2015-08-19 | Release date: | 2016-03-02 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Structural mechanism of ATP-dependent DNA binding and DNA end bridging by eukaryotic Rad50. Embo J., 35, 2016
|
|
5DAC
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5dac by Molmil](/molmil-images/mine/5dac) | ATP-gamma-S bound Rad50 from Chaetomium thermophilum in complex with DNA | Descriptor: | 4-(2-AMINOETHYL)BENZENESULFONYL FLUORIDE, DNA (5'-D(P*CP*CP*CP*CP*CP*CP*CP*CP*CP*CP*CP*CP*CP*CP*C)-3'), DNA (5'-D(P*GP*GP*GP*GP*GP*GP*GP*GP*GP*GP*GP*GP*GP*GP*G)-3'), ... | Authors: | Seifert, F.U, Lammens, K, Stoehr, G, Kessler, B, Hopfner, K.-P. | Deposit date: | 2015-08-19 | Release date: | 2016-03-02 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (2.503 Å) | Cite: | Structural mechanism of ATP-dependent DNA binding and DNA end bridging by eukaryotic Rad50. Embo J., 35, 2016
|
|
5EOM
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5eom by Molmil](/molmil-images/mine/5eom) | Structure of full-length human MAB21L1 with bound CTP | Descriptor: | CITRIC ACID, CYTIDINE-5'-TRIPHOSPHATE, Protein mab-21-like 1, ... | Authors: | de Oliveira Mann, C.C, Witte, G, Hopfner, K.-P. | Deposit date: | 2015-11-10 | Release date: | 2016-06-01 | Last modified: | 2024-05-01 | Method: | X-RAY DIFFRACTION (2.55 Å) | Cite: | Structural and biochemical characterization of the cell fate determining nucleotidyltransferase fold protein MAB21L1. Sci Rep, 6, 2016
|
|
5EOG
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5eog by Molmil](/molmil-images/mine/5eog) | |
3EIK
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3eik by Molmil](/molmil-images/mine/3eik) | |
3G9A
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3g9a by Molmil](/molmil-images/mine/3g9a) | Green fluorescent protein bound to minimizer nanobody | Descriptor: | Green fluorescent protein, Minimizer | Authors: | Kirchhofer, A, Helma, J, Schmidthals, K, Frauer, C, Cui, S, Karcher, A, Pellis, M, Muyldermans, S, Delucci, C.C, Cardoso, M.C, Leonhardt, H, Hopfner, K.-P, Rothbauer, U. | Deposit date: | 2009-02-13 | Release date: | 2009-12-08 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (1.614 Å) | Cite: | Modulation of protein properties in living cells using nanobodies Nat.Struct.Mol.Biol., 17, 2010
|
|
5N6I
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5n6i by Molmil](/molmil-images/mine/5n6i) | Crystal structure of mouse cGAS in complex with 39 bp DNA | Descriptor: | Cyclic GMP-AMP synthase, DNA (36-MER), DNA (37-MER), ... | Authors: | Andreeva, L, Kostrewa, D, Hopfner, K.-P. | Deposit date: | 2017-02-15 | Release date: | 2017-09-13 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (3.6 Å) | Cite: | cGAS senses long and HMGB/TFAM-bound U-turn DNA by forming protein-DNA ladders. Nature, 549, 2017
|
|
4FO0
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4fo0 by Molmil](/molmil-images/mine/4fo0) | Human actin-related protein Arp8 in its ATP-bound state | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, Actin-related protein 8, CHLORIDE ION, ... | Authors: | Gerhold, C.B, Lakomek, K, Seifert, F.U, Hopfner, K.-P. | Deposit date: | 2012-06-20 | Release date: | 2012-09-26 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Structure of Actin-related protein 8 and its contribution to nucleosome binding. Nucleic Acids Res., 40, 2012
|
|
3TBK
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3tbk by Molmil](/molmil-images/mine/3tbk) | Mouse RIG-I ATPase Domain | Descriptor: | 1,2-ETHANEDIOL, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, RIG-I Helicase Domain | Authors: | Civril, F, Bennett, M.D, Hopfner, K.-P. | Deposit date: | 2011-08-07 | Release date: | 2011-10-26 | Last modified: | 2017-11-08 | Method: | X-RAY DIFFRACTION (2.14 Å) | Cite: | The RIG-I ATPase domain structure reveals insights into ATP-dependent antiviral signalling. Embo Rep., 12, 2011
|
|
3TJ1
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3tj1 by Molmil](/molmil-images/mine/3tj1) | Crystal Structure of RNA Polymerase I Transcription Initiation Factor Rrn3 | Descriptor: | RNA polymerase I-specific transcription initiation factor RRN3 | Authors: | Blattner, C, Jennebach, S, Herzog, F, Mayer, A, Cheung, A.C.M, Witte, G, Lorenzen, K, Hopfner, K.-P, Heck, A.J.R, Aebersold, R, Cramer, P. | Deposit date: | 2011-08-23 | Release date: | 2011-09-28 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.85 Å) | Cite: | Molecular basis of Rrn3-regulated RNA polymerase I initiation and cell growth. Genes Dev., 25, 2011
|
|
7Z8S
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7z8s by Molmil](/molmil-images/mine/7z8s) | Mot1:TBP:DNA - post hydrolysis state | Descriptor: | DNA (36-MER), Helicase-like protein, Putative tata-box binding protein | Authors: | Woike, S, Eustermann, S, Jung, J, Wenzl, S.J, Hagemann, G, Bartho, J.D, Lammens, K, Butryn, A, Herzog, F, Hopfner, K.-P. | Deposit date: | 2022-03-18 | Release date: | 2023-03-29 | Last modified: | 2023-05-31 | Method: | ELECTRON MICROSCOPY (3.9 Å) | Cite: | Structural basis for TBP displacement from TATA box DNA by the Swi2/Snf2 ATPase Mot1. Nat.Struct.Mol.Biol., 30, 2023
|
|
7Z7N
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7z7n by Molmil](/molmil-images/mine/7z7n) | Mot1E1434Q:TBP:DNA - substrate recognition state | Descriptor: | DNA (36-MER), Helicase-like protein, Putative tata-box binding protein | Authors: | Woike, S, Eustermann, S, Jung, J, Wenzl, S.J, Hagemann, G, Bartho, J.D, Lammens, K, Butryn, A, Herzog, F, Hopfner, K.-P. | Deposit date: | 2022-03-16 | Release date: | 2023-03-29 | Last modified: | 2024-07-17 | Method: | ELECTRON MICROSCOPY (5.1 Å) | Cite: | Structural basis for TBP displacement from TATA box DNA by the Swi2/Snf2 ATPase Mot1. Nat.Struct.Mol.Biol., 30, 2023
|
|
7ZB5
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7zb5 by Molmil](/molmil-images/mine/7zb5) | Mot1(1-1836):TBP:DNA - post-hydrolysis complex dimer | Descriptor: | DNA (36-MER), Helicase-like protein, Putative tata-box binding protein | Authors: | Woike, S, Eustermann, S, Jung, J, Wenzl, S.J, Hagemann, G, Bartho, J.D, Lammens, K, Butryn, A, Herzog, F, Hopfner, K.-P. | Deposit date: | 2022-03-23 | Release date: | 2023-04-05 | Last modified: | 2023-05-31 | Method: | ELECTRON MICROSCOPY (2.8 Å) | Cite: | Structural basis for TBP displacement from TATA box DNA by the Swi2/Snf2 ATPase Mot1. Nat.Struct.Mol.Biol., 30, 2023
|
|
6GPG
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6gpg by Molmil](/molmil-images/mine/6gpg) | Structure of the RIG-I Singleton-Merten syndrome variant C268F | Descriptor: | MAGNESIUM ION, Probable ATP-dependent RNA helicase DDX58, RNA (5'-R(*CP*GP*AP*CP*GP*CP*UP*AP*GP*CP*GP*UP*CP*G)-3'), ... | Authors: | Laessig, C, Lammens, K, Hopfner, K.-P. | Deposit date: | 2018-06-05 | Release date: | 2018-08-08 | Last modified: | 2024-05-15 | Method: | X-RAY DIFFRACTION (2.894 Å) | Cite: | Unified mechanisms for self-RNA recognition by RIG-I Singleton-Merten syndrome variants. Elife, 7, 2018
|
|
6G7E
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6g7e by Molmil](/molmil-images/mine/6g7e) | |
7ZKE
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7zke by Molmil](/molmil-images/mine/7zke) | Mot1:TBP:DNA - pre-hydrolysis state | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, DNA (36-MER), ... | Authors: | Woike, S, Eustermann, S, Jung, J, Wenzl, S.J, Hagemann, G, Bartho, J.D, Lammens, K, Butryn, A, Herzog, F, Hopfner, K.-P. | Deposit date: | 2022-04-12 | Release date: | 2023-04-26 | Last modified: | 2023-05-31 | Method: | ELECTRON MICROSCOPY (3.6 Å) | Cite: | Structural basis for TBP displacement from TATA box DNA by the Swi2/Snf2 ATPase Mot1. Nat.Struct.Mol.Biol., 30, 2023
|
|
3J16
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3j16 by Molmil](/molmil-images/mine/3j16) | Models of ribosome-bound Dom34p and Rli1p and their ribosomal binding partners | Descriptor: | 18S ribosomal RNA, 28S ribosomal RNA, 40S ribosomal protein S24-A, ... | Authors: | Becker, T, Franckenberg, S, Wickles, S, Shoemaker, C.J, Anger, A.M, Armache, J.-P, Sieber, H, Ungewickell, C, Berninghausen, O, Daberkow, I, Karcher, A, Thomm, M, Hopfner, K.-P, Green, R, Beckmann, R. | Deposit date: | 2011-12-12 | Release date: | 2012-02-22 | Last modified: | 2024-02-21 | Method: | ELECTRON MICROSCOPY (7.2 Å) | Cite: | Structural basis of highly conserved ribosome recycling in eukaryotes and archaea. Nature, 482, 2012
|
|