8IMM
 
 | | Rs2'I-Rs2'II, Rs1'I-Rs1'II, Rb'I-Rb'II cylinder in cyanobacterial phycobilisome from Anthocerotibacter panamensis (Cluster E) | | Descriptor: | CpcA, CpcB, CpcD, ... | | Authors: | Wang, C.H, Yang, C.H, Wu, H.Y, Jiang, H.W, Ho, M.C, Ho, M.Y. | | Deposit date: | 2023-03-07 | | Release date: | 2023-10-25 | | Last modified: | 2024-05-08 | | Method: | ELECTRON MICROSCOPY (2.76 Å) | | Cite: | A structure of the relict phycobilisome from a thylakoid-free cyanobacterium.
Nat Commun, 14, 2023
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8IMO
 | | Rt1'I-Rt1'II, Rt2I-Rt2II, Rt3'I-Rt3'II cylinder in cyanobacterial phycobilisome from Anthocerotibacter panamensis (Cluster G) | | Descriptor: | CpcA, CpcB, CpcD, ... | | Authors: | Wang, C.H, Yang, C.H, Wu, H.Y, Jiang, H.W, Ho, M.C, Ho, M.Y. | | Deposit date: | 2023-03-07 | | Release date: | 2023-10-25 | | Last modified: | 2024-05-08 | | Method: | ELECTRON MICROSCOPY (3.08 Å) | | Cite: | A structure of the relict phycobilisome from a thylakoid-free cyanobacterium.
Nat Commun, 14, 2023
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6PNJ
 | | Structure of Photosystem I Acclimated to Far-red Light | | Descriptor: | 1,2-DIPALMITOYL-PHOSPHATIDYL-GLYCEROLE, 1,2-DISTEAROYL-MONOGALACTOSYL-DIGLYCERIDE, BETA-CAROTENE, ... | | Authors: | Gisriel, C.J, Shen, G, Kurashov, V, Ho, M, Zhang, S, Williams, D, Golbeck, J.H, Fromme, P, Bryant, D.A. | | Deposit date: | 2019-07-02 | | Release date: | 2020-02-12 | | Last modified: | 2020-02-26 | | Method: | ELECTRON MICROSCOPY (3.2 Å) | | Cite: | The structure of Photosystem I acclimated to far-red light illuminates an ecologically important acclimation process in photosynthesis
Sci Adv, 6, 2020
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7T62
 | | GPC2 HEP CT3 complex | | Descriptor: | CT3, Glypican-2 | | Authors: | Zhu, J, Cachau, R, De Val Alda, N, Li, N, Ho, M. | | Deposit date: | 2021-12-13 | | Release date: | 2021-12-22 | | Method: | ELECTRON MICROSCOPY (21 Å) | | Cite: | CAR T cells targeting tumor-associated exons of glypican 2 regress neuroblastoma in mice.
Cell Rep Med, 2, 2021
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3WRF
 | | The crystal structure of native HypBA1 from Bifidobacterium longum JCM 1217 | | Descriptor: | Non-reducing end beta-L-arabinofuranosidase | | Authors: | Huang, C.H, Zhu, Z, Cheng, Y.S, Chan, H.C, Ko, T.P, Chen, C.C, Wang, I, Ho, M.R, Hsu, S.T, Zeng, Y.F, Huang, Y.N, Liu, J.R, Guo, R.T. | | Deposit date: | 2014-02-25 | | Release date: | 2014-09-03 | | Method: | X-RAY DIFFRACTION (2.25 Å) | | Cite: | Structure and Catalytic Mechanism of a Glycoside Hydrolase Family-127 beta-L-Arabinofuranosidase (HypBA1)
J BIOPROCESS BIOTECH, 4, 2014
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3EWC
 | | Crystal Structure of adenosine deaminase from Plasmodial vivax in complex with MT-coformycin | | Descriptor: | (8R)-3-(5-S-methyl-5-thio-beta-D-ribofuranosyl)-3,6,7,8-tetrahydroimidazo[4,5-d][1,3]diazepin-8-ol, Adenosine deaminase, ZINC ION | | Authors: | Schramm, V.L, Almo, S.C, Cassera, M.B, Ho, M.C. | | Deposit date: | 2008-10-14 | | Release date: | 2009-09-22 | | Last modified: | 2023-12-27 | | Method: | X-RAY DIFFRACTION (2.11 Å) | | Cite: | Structural and metabolic specificity of methylthiocoformycin for malarial adenosine deaminases.
Biochemistry, 48, 2009
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7S3D
 | | Structure of photosystem I with bound ferredoxin from Synechococcus sp. PCC 7335 acclimated to far-red light | | Descriptor: | 1,2-DIPALMITOYL-PHOSPHATIDYL-GLYCEROLE, 1,2-DISTEAROYL-MONOGALACTOSYL-DIGLYCERIDE, 2Fe-2S ferredoxin-type domain-containing protein, ... | | Authors: | Gisriel, C.J, Flesher, D.A, Shen, G, Wang, J, Ho, M, Brudvig, G.W, Bryant, D.A. | | Deposit date: | 2021-09-05 | | Release date: | 2021-11-24 | | Last modified: | 2024-06-05 | | Method: | ELECTRON MICROSCOPY (2.91 Å) | | Cite: | Structure of a photosystem I-ferredoxin complex from a marine cyanobacterium provides insights into far-red light photoacclimation.
J.Biol.Chem., 298, 2021
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8JC7
 | | Cryo-EM structure of Vibrio campbellii alpha-hemolysin | | Descriptor: | CALCIUM ION, Hemolysin, POTASSIUM ION | | Authors: | Wang, C.H, Yeh, M.K, Ho, M.C, Lin, S.M. | | Deposit date: | 2023-05-10 | | Release date: | 2023-09-27 | | Last modified: | 2023-10-04 | | Method: | ELECTRON MICROSCOPY (2.06 Å) | | Cite: | Structural basis for calcium-stimulating pore formation of Vibrio alpha-hemolysin.
Nat Commun, 14, 2023
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7TPR
 | | Camel nanobodies 7A3 and 8A2 broadly neutralize SARS-CoV-2 variants | | Descriptor: | Nanobody 7A3, Nanobody 8A2, Spike glycoprotein | | Authors: | Butay, K.J, Zhu, J, Dandey, V.P, Hong, J, Kwon, H.J, Chen, C.Z, Duan, Z, Li, D, Ren, H, Liang, T, Martin, N, Esposito, D, Ortega-Rodriguez, U, Xu, M, Xie, H, Ho, M, Cachau, R, Borgnia, M.J. | | Deposit date: | 2022-01-25 | | Release date: | 2022-04-20 | | Method: | ELECTRON MICROSCOPY (2.39 Å) | | Cite: | Camel nanobodies broadly neutralize SARS-CoV-2 variants
bioRxiv, 2021
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3LMD
 | | Crystal structure of geranylgeranyl pyrophosphate synthase from corynebacterium glutamicum atcc 13032 | | Descriptor: | Geranylgeranyl pyrophosphate synthase | | Authors: | Patskovsky, Y, Ho, M, Toro, R, Rutter, M, Sauder, J.M, Burley, S.K, Almo, S.C, New York SGX Research Center for Structural Genomics (NYSGXRC) | | Deposit date: | 2010-01-29 | | Release date: | 2010-02-16 | | Last modified: | 2024-02-21 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | Crystal Structure of Geranylgeranyl Pyrophosphate Synthase from Corynebacterium Glutamicum
To be Published
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5VOE
 | | DesGla-XaS195A Bound to Aptamer 11F7t | | Descriptor: | Aptamer 11F7t (36-MER), CALCIUM ION, Coagulation factor X, ... | | Authors: | Gunaratne, R, Kumar, S, Frederiksen, J.W, Stayrook, S, Lohrmann, J.L, Perry, K, Chabata, C.V, Thalji, N.K, Ho, M.D, Arepally, G, Camire, R.M, Krishnaswamy, S.K, Sullenger, B.A. | | Deposit date: | 2017-05-02 | | Release date: | 2018-06-20 | | Last modified: | 2023-10-04 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Combination of aptamer and drug for reversible anticoagulation in cardiopulmonary bypass.
Nat. Biotechnol., 36, 2018
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8GYK
 | | CryoEM structure of the RAD51_ADP filament | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, DNA repair protein RAD51 homolog 1, MAGNESIUM ION | | Authors: | Miki, Y, Luo, S.C, Ho, M.C. | | Deposit date: | 2022-09-22 | | Release date: | 2023-08-30 | | Method: | ELECTRON MICROSCOPY (3.14 Å) | | Cite: | A RAD51-ADP double filament structure unveils the mechanism of filament dynamics in homologous recombination.
Nat Commun, 14, 2023
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4U3A
 | | Crystal structure of CtCel5E | | Descriptor: | Endoglucanase H | | Authors: | Yuan, S.F, Liang, P.H, Ho, M.C. | | Deposit date: | 2014-07-19 | | Release date: | 2015-01-14 | | Last modified: | 2024-03-20 | | Method: | X-RAY DIFFRACTION (2.42 Å) | | Cite: | Biochemical Characterization and Structural Analysis of a Bifunctional Cellulase/Xylanase from Clostridium thermocellum
J.Biol.Chem., 290, 2015
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7CGY
 | | Human DMC1 Q244M mutant of the post-synaptic complexes | | Descriptor: | CALCIUM ION, Meiotic recombination protein DMC1/LIM15 homolog, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER | | Authors: | Chi, H.Y, Ho, M.C, Tsai, M.D, Luo, S.C, Yeh, H.Y. | | Deposit date: | 2020-07-03 | | Release date: | 2020-11-18 | | Last modified: | 2024-03-27 | | Method: | ELECTRON MICROSCOPY (3.2 Å) | | Cite: | Identification of fidelity-governing factors in human recombinases DMC1 and RAD51 from cryo-EM structures.
Nat Commun, 12, 2021
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7C9C
 | | Human DMC1 pre-synaptic complexes | | Descriptor: | CALCIUM ION, DNA (5'-D(P*TP*TP*TP*TP*TP*TP*TP*TP*T)-3'), Meiotic recombination protein DMC1/LIM15 homolog, ... | | Authors: | Luo, S.C, Yeh, H.Y, Chi, P, Ho, M.C, Tsai, M.D. | | Deposit date: | 2020-06-05 | | Release date: | 2020-11-25 | | Last modified: | 2021-01-27 | | Method: | ELECTRON MICROSCOPY (3.33 Å) | | Cite: | Identification of fidelity-governing factors in human recombinases DMC1 and RAD51 from cryo-EM structures.
Nat Commun, 12, 2021
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7C99
 | | Human DMC1 post-synaptic complexes with mismatched dsDNA | | Descriptor: | CALCIUM ION, DNA (5'-D(P*AP*AP*AP*AP*AP*AP*AP*AP*A)-3'), DNA (5'-D(P*TP*TP*TP*TP*TP*TP*TP*TP*T)-3'), ... | | Authors: | Luo, S.C, Yeh, H.Y, Chi, P, Ho, M.C, Tsai, M.D. | | Deposit date: | 2020-06-05 | | Release date: | 2020-11-18 | | Last modified: | 2024-03-27 | | Method: | ELECTRON MICROSCOPY (3.36 Å) | | Cite: | Identification of fidelity-governing factors in human recombinases DMC1 and RAD51 from cryo-EM structures.
Nat Commun, 12, 2021
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7C9A
 | | Human RAD51 post-synaptic complexes mutant (V273P, D274G) | | Descriptor: | CALCIUM ION, DNA (5'-D(P*AP*AP*AP*AP*AP*AP*AP*AP*A)-3'), DNA (5'-D(P*TP*TP*TP*TP*TP*TP*TP*TP*T)-3'), ... | | Authors: | Chi, H.Y, Ho, M.C, Tsai, M.D, Luo, S.C, Yeh, H.Y. | | Deposit date: | 2020-06-05 | | Release date: | 2020-11-18 | | Last modified: | 2024-03-27 | | Method: | ELECTRON MICROSCOPY (3.43 Å) | | Cite: | Identification of fidelity-governing factors in human recombinases DMC1 and RAD51 from cryo-EM structures.
Nat Commun, 12, 2021
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7C98
 | | Human DMC1 post-synaptic complexes | | Descriptor: | CALCIUM ION, DNA (5'-D(P*AP*AP*AP*AP*AP*AP*AP*AP*A)-3'), DNA (5'-D(P*TP*TP*TP*TP*TP*TP*TP*TP*T)-3'), ... | | Authors: | Luo, S.C, Yeh, H.Y, Chi, P, Ho, M.C, Tsai, M.D. | | Deposit date: | 2020-06-05 | | Release date: | 2020-11-18 | | Last modified: | 2024-03-27 | | Method: | ELECTRON MICROSCOPY (3.47 Å) | | Cite: | Identification of fidelity-governing factors in human recombinases DMC1 and RAD51 from cryo-EM structures.
Nat Commun, 12, 2021
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5YQ4
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2N9W
 | | Solution NMR Structure of the membrane localization domain from the Ras/Rap1-specific endopeptidase (RRSP) of the Vibrio vulnificus multifunctional autoprocessing repeats-in-toxins (MARTX) toxin | | Descriptor: | RTX toxin | | Authors: | Hisao, G.S, Brothers, M.C, Ho, M, Wilson, B.A, Rienstra, C.M. | | Deposit date: | 2015-12-12 | | Release date: | 2016-12-07 | | Last modified: | 2024-05-15 | | Method: | SOLUTION NMR | | Cite: | The membrane localization domains of two distinct bacterial toxins form a 4-helix-bundle in solution.
Protein Sci., 26, 2017
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2N9V
 | | Solution NMR Structure of the membrane localization domain from Pasteurella multocida toxin | | Descriptor: | Dermonecrotic toxin | | Authors: | Hisao, G.S, Brothers, M.C, Ho, M, Wilson, B.A, Rienstra, C.M. | | Deposit date: | 2015-12-12 | | Release date: | 2016-12-07 | | Last modified: | 2024-05-15 | | Method: | SOLUTION NMR | | Cite: | The membrane localization domains of two distinct bacterial toxins form a 4-helix-bundle in solution.
Protein Sci., 26, 2017
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4X41
 | | Crystal Structure of Protein Arginine Methyltransferase PRMT8 | | Descriptor: | Protein arginine N-methyltransferase 8, S-ADENOSYL-L-HOMOCYSTEINE | | Authors: | Lee, W.C, Ho, M.C. | | Deposit date: | 2014-12-02 | | Release date: | 2015-11-18 | | Last modified: | 2024-03-20 | | Method: | X-RAY DIFFRACTION (3.5 Å) | | Cite: | Protein Arginine Methyltransferase 8: Tetrameric Structure and Protein Substrate Specificity
Biochemistry, 54, 2015
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3EWD
 | | Crystal structure of adenosine deaminase mutant (delta Asp172) from Plasmodium vivax in complex with MT-coformycin | | Descriptor: | (8R)-3-(5-S-methyl-5-thio-beta-D-ribofuranosyl)-3,6,7,8-tetrahydroimidazo[4,5-d][1,3]diazepin-8-ol, Adenosine deaminase, ZINC ION | | Authors: | Schramm, V.L, Almo, S.C, Cassera, M.B, Ho, M.C. | | Deposit date: | 2008-10-14 | | Release date: | 2009-09-22 | | Last modified: | 2023-12-27 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | Structural and metabolic specificity of methylthiocoformycin for malarial adenosine deaminases.
Biochemistry, 48, 2009
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7XDG
 | | Cryo-EM structures of human mitochondrial NAD(P)+-dependent malic enzyme in a ternary complex with NAD+ and allosteric inhibitor MDSA | | Descriptor: | 5-[(3-carboxy-4-oxidanyl-phenyl)methyl]-2-oxidanyl-benzoic acid, NAD-dependent malic enzyme, mitochondrial, ... | | Authors: | Wang, C.H, Hsieh, J.T, Ho, M.C, Hung, H.C. | | Deposit date: | 2022-03-27 | | Release date: | 2023-03-29 | | Last modified: | 2024-06-26 | | Method: | ELECTRON MICROSCOPY (2.84 Å) | | Cite: | Suppression of the human malic enzyme 2 modifies energy metabolism and inhibits cellular respiration
Commun Biol, 6, 2023
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7XDF
 | | Cryo-EM structures of human mitochondrial NAD(P)+-dependent malic enzyme in a ternary complex with NAD+ and allosteric inhibitor EA | | Descriptor: | 4-[(3-carboxy-2-oxidanyl-naphthalen-1-yl)methyl]-3-oxidanyl-naphthalene-2-carboxylic acid, NAD-dependent malic enzyme, mitochondrial, ... | | Authors: | Wang, C.H, Hsieh, J.T, Ho, M.C, Hung, H.C. | | Deposit date: | 2022-03-27 | | Release date: | 2023-03-29 | | Last modified: | 2023-05-31 | | Method: | ELECTRON MICROSCOPY (2.72 Å) | | Cite: | Suppression of the human malic enzyme 2 modifies energy metabolism and inhibits cellular respiration
Commun Biol, 6, 2023
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