7C99

Human DMC1 post-synaptic complexes with mismatched dsDNA

Summary for 7C99

• Entry DOI: 10.2210/pdb7c99/pdb
• EMDB information: 30309
• Descriptor: Meiotic recombination protein DMC1/LIM15 homolog, DNA (5'-D(P*TP*TP*TP*TP*TP*TP*TP*TP*T)-3'), DNA (5'-D(P*AP*AP*AP*AP*AP*AP*AP*AP*A)-3'), ... (5 entities in total)
• Functional Keywords: meiotic homologous recombination, dna repair, atpase, recombination, recombination-dna complex, recombination/dna
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 5
• Total formula weight: 120298.60

Authors

Luo, S.C.,Yeh, H.Y.,Chi, P.,Ho, M.C.,Tsai, M.D. (deposition date: 2020-06-05, release date: 2020-11-18, Last modification date: 2024-03-27)

• Primary citation: Luo, S.C.,Yeh, H.Y.,Lan, W.H.,Wu, Y.M.,Yang, C.H.,Chang, H.Y.,Su, G.C.,Lee, C.Y.,Wu, W.J.,Li, H.W.,Ho, M.C.,Chi, P.,Tsai, M.D.; Identification of fidelity-governing factors in human recombinases DMC1 and RAD51 from cryo-EM structures.; Nat Commun, 12:115-115, 2021; PubMed: 33446654; DOI: 10.1038/s41467-020-20258-1

Experimental method

ELECTRON MICROSCOPY (3.36 Å)