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PDB: 27 results

6OSI
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BU of 6osi by Molmil
Unmodified tRNA(Pro) bound to Thermus thermophilus 70S (near cognate)
Descriptor: 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ...
Authors:Hoffer, E.D, Subaramanian, S, Hong, S, Maehigashi, T, Dunham, C.M.
Deposit date:2019-05-01
Release date:2020-10-14
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (4.14 Å)
Cite:Structural insights into mRNA reading frame regulation by tRNA modification and slippery codon-anticodon pairing.
Elife, 9, 2020
5CZP
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BU of 5czp by Molmil
70S termination complex containing E. coli RF2
Descriptor: 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ...
Authors:Hoffer, E.D, Dunham, C.M.
Deposit date:2015-07-31
Release date:2016-10-12
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (3.29995918 Å)
Cite:Uniformity of Peptide Release Is Maintained by Methylation of Release Factors.
Cell Rep, 17, 2016
5DFE
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BU of 5dfe by Molmil
70S termination complex containing E. coli RF2
Descriptor: 16S rRNA, 30S ribosomal protein S10, 30S ribosomal protein S11, ...
Authors:Hoffer, E.D, Dunham, C.M.
Deposit date:2015-08-26
Release date:2016-10-12
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (3.09997559 Å)
Cite:Uniformity of Peptide Release Is Maintained by Methylation of Release Factors.
Cell Rep, 17, 2016
5J30
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BU of 5j30 by Molmil
Thermus thermophilus 70S termination complex containing E. coli RF1
Descriptor: 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ...
Authors:Hoffer, E.D, Dunham, C.M.
Deposit date:2016-03-30
Release date:2016-10-12
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Uniformity of Peptide Release Is Maintained by Methylation of Release Factors.
Cell Rep, 17, 2016
5J3C
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BU of 5j3c by Molmil
Thermus thermophilus 70S termination complex containing E. coli RF1
Descriptor: 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ...
Authors:Hoffer, E.D, Dunham, C.M.
Deposit date:2016-03-30
Release date:2016-10-12
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (3.04 Å)
Cite:Uniformity of Peptide Release Is Maintained by Methylation of Release Factors.
Cell Rep, 17, 2016
6OM6
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BU of 6om6 by Molmil
Structure of trans-translation inhibitor bound to E. coli 70S ribosome with P site tRNA
Descriptor: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ...
Authors:Hoffer, E.D, Mehrani, A, Keiler, K.C, Stagg, S.M, Dunham, C.M.
Deposit date:2019-04-18
Release date:2021-02-10
Last modified:2024-11-06
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:trans-Translation inhibitors bind to a novel site on the ribosome and clear Neisseria gonorrhoeae in vivo.
Nat Commun, 12, 2021
6NWY
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BU of 6nwy by Molmil
Modified tRNA(Pro) bound to Thermus thermophilus 70S (near-cognate)
Descriptor: 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ...
Authors:Hoffer, E.D, Subaramanian, S, Hong, S, Maehigashi, T, Dunham, C.M.
Deposit date:2019-02-07
Release date:2020-10-14
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (3.5 Å)
Cite:Structural insights into mRNA reading frame regulation by tRNA modification and slippery codon-anticodon pairing.
Elife, 9, 2020
6NUO
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BU of 6nuo by Molmil
Modified tRNA(Pro) bound to Thermus thermophilus 70S (cognate)
Descriptor: 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ...
Authors:Hoffer, E.D, Subaramanian, S, Hong, S, Maehigashi, T, Dunham, C.M.
Deposit date:2019-02-01
Release date:2020-10-14
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Structural insights into mRNA reading frame regulation by tRNA modification and slippery codon-anticodon pairing.
Elife, 9, 2020
6NSH
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BU of 6nsh by Molmil
Modified ASL proline bound to Thermus thermophilus 70S (near-cognate)
Descriptor: 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ...
Authors:Hoffer, E.D, Maehigashi, T, Subaramanian, S, Hong, S, Dunham, C.M.
Deposit date:2019-01-24
Release date:2020-10-14
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (3.397 Å)
Cite:Structural insights into mRNA reading frame regulation by tRNA modification and slippery codon-anticodon pairing.
Elife, 9, 2020
6O3M
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BU of 6o3m by Molmil
Unmodified tRNA(Pro) bound to Thermus thermophilus 70S (cognate)
Descriptor: 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ...
Authors:Hoffer, E.D, Subaramanian, S, Hong, S, Maehigashi, T, Dunham, C.M.
Deposit date:2019-02-26
Release date:2020-10-14
Last modified:2024-11-06
Method:X-RAY DIFFRACTION (3.97 Å)
Cite:Structural insights into mRNA reading frame regulation by tRNA modification and slippery codon-anticodon pairing.
Elife, 9, 2020
6NTA
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BU of 6nta by Molmil
Modified ASL proline bound to Thermus thermophilus 70S (cognate)
Descriptor: 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ...
Authors:Hoffer, E.D, Maehigashi, T, Subaramanian, S, Hong, S, Dunham, C.M.
Deposit date:2019-01-28
Release date:2020-10-14
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Structural insights into mRNA reading frame regulation by tRNA modification and slippery codon-anticodon pairing.
Elife, 9, 2020
6BZ8
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BU of 6bz8 by Molmil
Thermus thermophilus 70S containing 16S G347U point mutation and near-cognate ASL Leucine in A site
Descriptor: 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ...
Authors:Hoffer, E.D, Maehigashi, T, Fagan, C.E, Dunham, C.M.
Deposit date:2017-12-22
Release date:2018-11-14
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (3.74 Å)
Cite:Ribosomal ambiguity (ram) mutations promote the open (off) to closed (on) transition and thereby increase miscoding.
Nucleic Acids Res., 47, 2019
6BZ7
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BU of 6bz7 by Molmil
Thermus thermophilus 70S containing 16S G299A point mutation and near-cognate ASL Leucine in A site.
Descriptor: 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ...
Authors:Hoffer, E.D, Maehigashi, T, Fagan, C.E, Dunham, C.M.
Deposit date:2017-12-22
Release date:2018-11-14
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (3.68 Å)
Cite:Ribosomal ambiguity (ram) mutations promote the open (off) to closed (on) transition and thereby increase miscoding.
Nucleic Acids Res., 47, 2019
6BUW
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BU of 6buw by Molmil
Thermus thermophilus 70S complex containing 16S G299A ram mutation and empty A site.
Descriptor: 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ...
Authors:Hoffer, E.D, Maehigashi, T, Fagan, C.E, Dunham, C.M.
Deposit date:2017-12-11
Release date:2018-11-14
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (3.5 Å)
Cite:Ribosomal ambiguity (ram) mutations promote the open (off) to closed (on) transition and thereby increase miscoding.
Nucleic Acids Res., 47, 2019
6BZ6
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BU of 6bz6 by Molmil
Thermus thermophilus 70S complex containing 16S G347U ram mutation and empty A site
Descriptor: 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ...
Authors:Hoffer, E.D, Maehigashi, T, Fagan, C.E, Dunham, C.M.
Deposit date:2017-12-22
Release date:2018-11-14
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (3.18 Å)
Cite:Ribosomal ambiguity (ram) mutations promote the open (off) to closed (on) transition and thereby increase miscoding.
Nucleic Acids Res., 47, 2019
6CEP
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BU of 6cep by Molmil
Sus scrofa heart L-lactate dehydrogenase ternary complex with NADH and oxamate
Descriptor: L-lactate dehydrogenase B chain, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, OXAMIC ACID
Authors:Hoffer, E.D, Andrews, B, Dunham, C.M, Dyer, R.B.
Deposit date:2018-02-12
Release date:2018-06-27
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2 Å)
Cite:Small molecule cores demonstrate non-competitive inhibition of lactate dehydrogenase.
Medchemcomm, 9, 2018
6OTR
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BU of 6otr by Molmil
Dimeric E.coli YoeB bound to Thermus thermophilus 70S post-cleavage (AAU)
Descriptor: 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ...
Authors:Pavelich, I.P, Hoffer, E.D, Maehigashi, T, Dunham, C.M.
Deposit date:2019-05-03
Release date:2019-08-21
Last modified:2024-11-20
Method:X-RAY DIFFRACTION (3.12 Å)
Cite:Monomeric YoeB toxin retains RNase activity but adopts an obligate dimeric form for thermal stability.
Nucleic Acids Res., 47, 2019
8FOM
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BU of 8fom by Molmil
Crystal structure of tRNA^Lys(SUU) bound to UAA codon in the ribosomal P site
Descriptor: 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ...
Authors:Nguyen, H.A, Hoffer, E.D, Maehigashi, T, Fagan, C.E, Dunham, C.M.
Deposit date:2023-01-02
Release date:2023-03-29
Last modified:2024-10-23
Method:X-RAY DIFFRACTION (3.58 Å)
Cite:Structural basis for reduced ribosomal A-site fidelity in response to P-site codon-anticodon mismatches.
J.Biol.Chem., 299, 2023
8FON
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BU of 8fon by Molmil
Crystal structure of tRNA^Lys(SUU) bound to AUA codon in the ribosomal P site
Descriptor: 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ...
Authors:Nguyen, H.A, Hoffer, E.D, Maehigashi, T, Fagan, C.E, Dunham, C.M.
Deposit date:2023-01-02
Release date:2023-03-29
Last modified:2024-05-22
Method:X-RAY DIFFRACTION (3.64 Å)
Cite:Structural basis for reduced ribosomal A-site fidelity in response to P-site codon-anticodon mismatches.
J.Biol.Chem., 299, 2023
6PQB
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BU of 6pqb by Molmil
Crystal structure of aminoglycoside-resistance methyltransferase RmtC bound to S-adenosylhomocysteine (SAH)
Descriptor: 16S rRNA (guanine(1405)-N(7))-methyltransferase, S-ADENOSYL-L-HOMOCYSTEINE
Authors:Nosrati, M, Hoffer, E.D, Conn, G.L.
Deposit date:2019-07-08
Release date:2019-10-16
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (3.14 Å)
Cite:Functionally critical residues in the aminoglycoside resistance-associated methyltransferase RmtC play distinct roles in 30S substrate recognition.
J.Biol.Chem., 294, 2019
6OXI
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BU of 6oxi by Molmil
Dimeric E.coli YoeB bound to Thermus thermophilus 70S post-cleavage (UAA)
Descriptor: 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ...
Authors:Pavelich, I.J, Hoffer, E.D, Maehigashi, T, Dunham, C.M.
Deposit date:2019-05-13
Release date:2019-08-21
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (3.495 Å)
Cite:Monomeric YoeB toxin retains RNase activity but adopts an obligate dimeric form for thermal stability.
Nucleic Acids Res., 47, 2019
6OXA
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BU of 6oxa by Molmil
Dimeric E.coli YoeB bound to Thermus thermophilus 70S pre-cleavage (AAU)
Descriptor: 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ...
Authors:Pavelich, I.J, Hoffer, E.D, Maehigashi, T, Dunham, C.M.
Deposit date:2019-05-13
Release date:2019-08-21
Last modified:2024-10-30
Method:X-RAY DIFFRACTION (3.25 Å)
Cite:Monomeric YoeB toxin retains RNase activity but adopts an obligate dimeric form for thermal stability.
Nucleic Acids Res., 47, 2019
6CF1
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BU of 6cf1 by Molmil
Proteus vulgaris HigA antitoxin structure
Descriptor: Antitoxin HigA, POTASSIUM ION
Authors:Schureck, M.A, Hoffer, E.D, Ei Cho, S, Dunham, C.M.
Deposit date:2018-02-13
Release date:2019-02-27
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structural basis of transcriptional regulation by the HigA antitoxin.
Mol.Microbiol., 111, 2019
6CHV
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BU of 6chv by Molmil
Proteus vulgaris HigA antitoxin bound to DNA
Descriptor: Antitoxin HigA, MAGNESIUM ION, pHigCryst3, ...
Authors:Schureck, M.A, Hoffer, E.D, Onuoha, N, Dunham, C.M.
Deposit date:2018-02-23
Release date:2019-02-27
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Structural basis of transcriptional regulation by the HigA antitoxin.
Mol.Microbiol., 111, 2019
6M9A
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BU of 6m9a by Molmil
Bordetella pertussis globin coupled sensor regulatory domain (BpeGReg)
Descriptor: CALCIUM ION, HYDROGEN PEROXIDE, PROTOPORPHYRIN IX CONTAINING FE, ...
Authors:Rivera, S.R, Hoffer, E.D, Dunham, C.M, Weinert, E.E.
Deposit date:2018-08-23
Release date:2018-11-14
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structural Insights into Oxygen-Dependent Signal Transduction within Globin Coupled Sensors.
Inorg Chem, 57, 2018

 

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