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PDB: 50 件

3DKL
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Crystal structure of phosphorylated mimic form of human NAMPT complexed with benzamide and phosphoribosyl pyrophosphate
分子名称: 1-O-pyrophosphono-5-O-phosphono-alpha-D-ribofuranose, BENZAMIDE, BERYLLIUM TRIFLUORIDE ION, ...
著者Ho, M, Burgos, E.S, Almo, S.C, Schramm, V.L.
登録日2008-06-25
公開日2009-08-18
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.89 Å)
主引用文献A phosphoenzyme mimic, overlapping catalytic sites and reaction coordinate motion for human NAMPT.
Proc.Natl.Acad.Sci.USA, 106, 2009
3DHD
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Crystal structure of human NAMPT complexed with nicotinamide mononucleotide and pyrophosphate
分子名称: BETA-NICOTINAMIDE RIBOSE MONOPHOSPHATE, MAGNESIUM ION, Nicotinamide phosphoribosyltransferase, ...
著者Ho, M, Burgos, E.S, Almo, S.C, Schramm, V.L.
登録日2008-06-17
公開日2009-08-18
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献A phosphoenzyme mimic, overlapping catalytic sites and reaction coordinate motion for human NAMPT.
Proc.Natl.Acad.Sci.USA, 106, 2009
3DKJ
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BU of 3dkj by Molmil
Crystal structure of human NAMPT complexed with benzamide and phosphoribosyl pyrophosphate
分子名称: 1-O-pyrophosphono-5-O-phosphono-alpha-D-ribofuranose, BENZAMIDE, Nicotinamide phosphoribosyltransferase
著者Ho, M, Burgos, E.S, Almo, S.C, Schramm, V.L.
登録日2008-06-25
公開日2009-08-18
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献A phosphoenzyme mimic, overlapping catalytic sites and reaction coordinate motion for human NAMPT.
Proc.Natl.Acad.Sci.USA, 106, 2009
3DGR
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Crystal structure of human NAMPT complexed with ADP analogue
分子名称: Nicotinamide phosphoribosyltransferase, PHOSPHOMETHYLPHOSPHONIC ACID ADENOSYL ESTER
著者Ho, M, Burgos, E.S, Almo, S.C, Schramm, V.L.
登録日2008-06-15
公開日2009-08-18
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献A phosphoenzyme mimic, overlapping catalytic sites and reaction coordinate motion for human NAMPT.
Proc.Natl.Acad.Sci.USA, 106, 2009
3DHF
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BU of 3dhf by Molmil
Crystal structure of phosphorylated mimic form of human NAMPT complexed with nicotinamide mononucleotide and pyrophosphate
分子名称: BERYLLIUM TRIFLUORIDE ION, BETA-NICOTINAMIDE RIBOSE MONOPHOSPHATE, MAGNESIUM ION, ...
著者Ho, M, Burgos, E.S, Almo, S.C, Schramm, V.L.
登録日2008-06-17
公開日2009-08-18
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献A phosphoenzyme mimic, overlapping catalytic sites and reaction coordinate motion for human NAMPT.
Proc.Natl.Acad.Sci.USA, 106, 2009
3HIO
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BU of 3hio by Molmil
Crystal structure of Ricin A-chain in complex with the cyclic tetranucleotide inhibitor, a transition state analogue
分子名称: 9,9'-{(2R,3R,3aR,5S,7aR,9R,10R,10aR,12S,23R,25aR,27R,28R,28aR,30S,32aR,35aR,37S,39aR)-9-(6-amino-9H-purin-9-yl)-34-[(4-amino-5H-pyrrolo[3,2-d]pyrimidin-7-yl)methyl]-5,12,23,30,37-pentahydroxy-3,10,28-trimethoxy-5,12,23,30,37-pentaoxidotetracosahydro-2H,7H,25H-trifuro[3,2-f:3',2'-l:3'',2''-x]pyrrolo[3,4-r][1,3,5,9,11,15,17,21,23,27,29,2,4,10,16,22,28]undecaoxazapentaphosphacyclopentatriacontine-2,27-diyl}bis(2-amino-3,9-dihydro-6H-purin-6-one), Ricin, SULFATE ION
著者Ho, M, Sturm, M.B, Goldman, J.D, Almo, S.C, Schramm, V.L.
登録日2009-05-20
公開日2009-12-08
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Transition state analogues in structures of ricin and saporin ribosome-inactivating proteins.
Proc.Natl.Acad.Sci.USA, 106, 2009
3HIW
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Crystal structure of Saporin-L1 in complex with the cyclic tetranucleotide inhibitor, a transition state analogue
分子名称: 9,9'-{(2R,3R,3aR,5S,7aR,9R,10R,10aR,12S,23R,25aR,27R,28R,28aR,30S,32aR,35aR,37S,39aR)-9-(6-amino-9H-purin-9-yl)-34-[(4-amino-5H-pyrrolo[3,2-d]pyrimidin-7-yl)methyl]-5,12,23,30,37-pentahydroxy-3,10,28-trimethoxy-5,12,23,30,37-pentaoxidotetracosahydro-2H,7H,25H-trifuro[3,2-f:3',2'-l:3'',2''-x]pyrrolo[3,4-r][1,3,5,9,11,15,17,21,23,27,29,2,4,10,16,22,28]undecaoxazapentaphosphacyclopentatriacontine-2,27-diyl}bis(2-amino-3,9-dihydro-6H-purin-6-one), Vacuolar saporin
著者Ho, M, Sturm, M.B, Almo, S.C, Schramm, V.L.
登録日2009-05-20
公開日2009-12-08
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Transition state analogues in structures of ricin and saporin ribosome-inactivating proteins.
Proc.Natl.Acad.Sci.USA, 106, 2009
3DP9
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BU of 3dp9 by Molmil
Crystal structure of Vibrio cholerae 5'-methylthioadenosine/S-adenosyl homocysteine nucleosidase (MTAN) complexed with butylthio-DADMe-Immucillin A
分子名称: (3R,4S)-1-[(4-amino-5H-pyrrolo[3,2-d]pyrimidin-7-yl)methyl]-4-[(butylsulfanyl)methyl]pyrrolidin-3-ol, IODIDE ION, MTA/SAH nucleosidase
著者Ho, M, Gutierrez, J.A, Crowder, T, Rinaldo-Matthis, A, Almo, S.C, Schramm, V.L.
登録日2008-07-07
公開日2009-03-10
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Transition state analogs of 5'-methylthioadenosine nucleosidase disrupt quorum sensing.
Nat.Chem.Biol., 5, 2009
7T62
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BU of 7t62 by Molmil
GPC2 HEP CT3 complex
分子名称: CT3, Glypican-2
著者Zhu, J, Cachau, R, De Val Alda, N, Li, N, Ho, M.
登録日2021-12-13
公開日2021-12-22
実験手法ELECTRON MICROSCOPY (21 Å)
主引用文献CAR T cells targeting tumor-associated exons of glypican 2 regress neuroblastoma in mice.
Cell Rep Med, 2, 2021
6PNJ
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BU of 6pnj by Molmil
Structure of Photosystem I Acclimated to Far-red Light
分子名称: 1,2-DIPALMITOYL-PHOSPHATIDYL-GLYCEROLE, 1,2-DISTEAROYL-MONOGALACTOSYL-DIGLYCERIDE, BETA-CAROTENE, ...
著者Gisriel, C.J, Shen, G, Kurashov, V, Ho, M, Zhang, S, Williams, D, Golbeck, J.H, Fromme, P, Bryant, D.A.
登録日2019-07-02
公開日2020-02-12
最終更新日2020-02-26
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献The structure of Photosystem I acclimated to far-red light illuminates an ecologically important acclimation process in photosynthesis
Sci Adv, 6, 2020
3LMD
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BU of 3lmd by Molmil
Crystal structure of geranylgeranyl pyrophosphate synthase from corynebacterium glutamicum atcc 13032
分子名称: Geranylgeranyl pyrophosphate synthase
著者Patskovsky, Y, Ho, M, Toro, R, Rutter, M, Sauder, J.M, Burley, S.K, Almo, S.C, New York SGX Research Center for Structural Genomics (NYSGXRC)
登録日2010-01-29
公開日2010-02-16
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Crystal Structure of Geranylgeranyl Pyrophosphate Synthase from Corynebacterium Glutamicum
To be Published
7TPR
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BU of 7tpr by Molmil
Camel nanobodies 7A3 and 8A2 broadly neutralize SARS-CoV-2 variants
分子名称: Nanobody 7A3, Nanobody 8A2, Spike glycoprotein
著者Butay, K.J, Zhu, J, Dandey, V.P, Hong, J, Kwon, H.J, Chen, C.Z, Duan, Z, Li, D, Ren, H, Liang, T, Martin, N, Esposito, D, Ortega-Rodriguez, U, Xu, M, Xie, H, Ho, M, Cachau, R, Borgnia, M.J.
登録日2022-01-25
公開日2022-04-20
実験手法ELECTRON MICROSCOPY (2.39 Å)
主引用文献Camel nanobodies broadly neutralize SARS-CoV-2 variants
bioRxiv, 2021
7S3D
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BU of 7s3d by Molmil
Structure of photosystem I with bound ferredoxin from Synechococcus sp. PCC 7335 acclimated to far-red light
分子名称: 1,2-DIPALMITOYL-PHOSPHATIDYL-GLYCEROLE, 1,2-DISTEAROYL-MONOGALACTOSYL-DIGLYCERIDE, 2Fe-2S ferredoxin-type domain-containing protein, ...
著者Gisriel, C.J, Flesher, D.A, Shen, G, Wang, J, Ho, M, Brudvig, G.W, Bryant, D.A.
登録日2021-09-05
公開日2021-11-24
最終更新日2024-06-05
実験手法ELECTRON MICROSCOPY (2.91 Å)
主引用文献Structure of a photosystem I-ferredoxin complex from a marine cyanobacterium provides insights into far-red light photoacclimation.
J.Biol.Chem., 298, 2021
2N9W
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BU of 2n9w by Molmil
Solution NMR Structure of the membrane localization domain from the Ras/Rap1-specific endopeptidase (RRSP) of the Vibrio vulnificus multifunctional autoprocessing repeats-in-toxins (MARTX) toxin
分子名称: RTX toxin
著者Hisao, G.S, Brothers, M.C, Ho, M, Wilson, B.A, Rienstra, C.M.
登録日2015-12-12
公開日2016-12-07
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献The membrane localization domains of two distinct bacterial toxins form a 4-helix-bundle in solution.
Protein Sci., 26, 2017
2N9V
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BU of 2n9v by Molmil
Solution NMR Structure of the membrane localization domain from Pasteurella multocida toxin
分子名称: Dermonecrotic toxin
著者Hisao, G.S, Brothers, M.C, Ho, M, Wilson, B.A, Rienstra, C.M.
登録日2015-12-12
公開日2016-12-07
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献The membrane localization domains of two distinct bacterial toxins form a 4-helix-bundle in solution.
Protein Sci., 26, 2017
3D4P
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BU of 3d4p by Molmil
Crystal structure of Lactate Dehydrogenase from Staphylococcus Aureus complexed with NAD and pyruvate
分子名称: L-lactate dehydrogenase 1, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, PYRUVIC ACID
著者Schramm, V.L, Almo, S.C, Gutierrez, J.A, Ho, M.
登録日2008-05-14
公開日2009-06-02
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Crystal structure of Lactate Dehydrogenase from Staphylococcus Aureus complexed with NAD and pyruvate
To be Published
7YUU
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MtaLon-ADP for the spiral oligomers of trimer
分子名称: Lon protease
著者Li, S, Hsieh, K, Kuo, C, Lee, S, Ho, M, Wang, C, Zhang, K, Chang, C.I.
登録日2022-08-17
公開日2023-10-25
最終更新日2024-04-03
実験手法ELECTRON MICROSCOPY (5.8 Å)
主引用文献A 5+1 assemble-to-activate mechanism of the Lon proteolytic machine.
Nat Commun, 14, 2023
7YUV
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BU of 7yuv by Molmil
MtaLon-ADP for the spiral oligomers of tetramer
分子名称: ADENOSINE-5'-DIPHOSPHATE, Lon protease
著者Li, S, Hsieh, K, Kuo, C, Lee, S, Ho, M, Wang, C, Zhang, K, Chang, C.I.
登録日2022-08-17
公開日2023-10-25
最終更新日2024-04-03
実験手法ELECTRON MICROSCOPY (3.8 Å)
主引用文献A 5+1 assemble-to-activate mechanism of the Lon proteolytic machine.
Nat Commun, 14, 2023
7YUW
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BU of 7yuw by Molmil
MtaLon-ADP for the spiral oligomers of pentamer
分子名称: ADENOSINE-5'-DIPHOSPHATE, Lon protease
著者Li, S, Hsieh, K, Kuo, C, Lee, S, Ho, M, Wang, C, Zhang, K, Chang, C.I.
登録日2022-08-18
公開日2023-10-25
最終更新日2024-04-03
実験手法ELECTRON MICROSCOPY (3.6 Å)
主引用文献A 5+1 assemble-to-activate mechanism of the Lon proteolytic machine.
Nat Commun, 14, 2023
7YUM
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BU of 7yum by Molmil
MtaLon-Apo for the spiral oligomers of tetramer
分子名称: Lon protease
著者Li, S, Hsieh, K, Kuo, C, Lee, S, Ho, M, Wang, C, Zhang, K, Chang, C.I.
登録日2022-08-17
公開日2023-10-25
最終更新日2024-04-03
実験手法ELECTRON MICROSCOPY (3.8 Å)
主引用文献A 5+1 assemble-to-activate mechanism of the Lon proteolytic machine.
Nat Commun, 14, 2023
7YUH
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BU of 7yuh by Molmil
MtaLon-Apo for the spiral oligomers of trimer
分子名称: Lon protease
著者Li, S, Hsieh, K, Kuo, C, Lee, S, Ho, M, Wang, C, Zhang, K, Chang, C.I.
登録日2022-08-17
公開日2023-10-25
最終更新日2024-04-03
実験手法ELECTRON MICROSCOPY (3.7 Å)
主引用文献A 5+1 assemble-to-activate mechanism of the Lon proteolytic machine.
Nat Commun, 14, 2023
7YUP
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BU of 7yup by Molmil
MtaLon-Apo for the spiral oligomers of pentamer
分子名称: Lon protease
著者Li, S, Hsieh, K, Kuo, C, Lee, S, Ho, M, Wang, C, Zhang, K, Chang, C.I.
登録日2022-08-17
公開日2023-10-25
最終更新日2024-04-03
実験手法ELECTRON MICROSCOPY (3.7 Å)
主引用文献A 5+1 assemble-to-activate mechanism of the Lon proteolytic machine.
Nat Commun, 14, 2023
7YUT
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BU of 7yut by Molmil
MtaLon-Apo for the spiral oligomers of hexamer
分子名称: Lon protease
著者Li, S, Hsieh, K, Kuo, C, Lee, S, Ho, M, Wang, C, Zhang, K, Chang, C.I.
登録日2022-08-17
公開日2023-10-25
最終更新日2024-04-03
実験手法ELECTRON MICROSCOPY (4.1 Å)
主引用文献A 5+1 assemble-to-activate mechanism of the Lon proteolytic machine.
Nat Commun, 14, 2023
7YUX
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BU of 7yux by Molmil
MtaLon-ADP for the spiral oligomers of hexamer
分子名称: ADENOSINE-5'-DIPHOSPHATE, Lon protease
著者Li, S, Hsieh, K, Kuo, C, Lee, S, Ho, M, Wang, C, Zhang, K, Chang, C.I.
登録日2022-08-18
公開日2023-10-25
最終更新日2024-04-03
実験手法ELECTRON MICROSCOPY (3.8 Å)
主引用文献A 5+1 assemble-to-activate mechanism of the Lon proteolytic machine.
Nat Commun, 14, 2023
3CHG
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BU of 3chg by Molmil
The compatible solute-binding protein OpuAC from Bacillus subtilis in complex with DMSA
分子名称: (dimethyl-lambda~4~-sulfanyl)acetic acid, Glycine betaine-binding protein
著者Smits, S.H.J, Hoing, M, Lecher, J, Jebbar, M, Schmitt, L, Bremer, E.
登録日2008-03-09
公開日2008-08-12
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献The Compatible-Solute-Binding Protein OpuAC from Bacillus subtilis: Ligand Binding, Site-Directed Mutagenesis, and Crystallographic Studies
J.Bacteriol., 190, 2008
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