4XTR
 
 | | Structure of Get3 bound to the transmembrane domain of Pep12 | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ATPase GET3, ... | | Authors: | Mateja, A, Paduch, M, Chang, H.-Y, Szydlowska, A, Kossiakoff, A.A, Hegde, R.S, Keenan, R.J. | | Deposit date: | 2015-01-23 | | Release date: | 2015-03-18 | | Last modified: | 2023-09-27 | | Method: | X-RAY DIFFRACTION (2.05 Å) | | Cite: | Protein targeting. Structure of the Get3 targeting factor in complex with its membrane protein cargo.
Science, 347, 2015
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8RJC
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8RJD
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8RJB
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7TM3
 | | Structure of the rabbit 80S ribosome stalled on a 2-TMD Rhodopsin intermediate in complex with the multipass translocon | | Descriptor: | 28S ribosomal RNA, 5.8S ribosomal RNA, 5S ribosomal RNA, ... | | Authors: | Kim, M.K, Lewis, A.J.O, Keenan, R.J, Hegde, R.S. | | Deposit date: | 2022-01-19 | | Release date: | 2022-10-19 | | Last modified: | 2024-06-05 | | Method: | ELECTRON MICROSCOPY (3.25 Å) | | Cite: | Mechanism of an intramembrane chaperone for multipass membrane proteins.
Nature, 611, 2022
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7TUT
 | | Structure of the rabbit 80S ribosome stalled on a 4-TMD Rhodopsin intermediate in complex with the multipass translocon | | Descriptor: | 28S ribosomal RNA, 5.8S ribosomal RNA, 5S ribosomal RNA, ... | | Authors: | Kim, M.K, Lewis, A.J.O, Keenan, R.J, Hegde, R.S. | | Deposit date: | 2022-02-03 | | Release date: | 2022-10-19 | | Last modified: | 2024-06-12 | | Method: | ELECTRON MICROSCOPY (3.88 Å) | | Cite: | Mechanism of an intramembrane chaperone for multipass membrane proteins.
Nature, 611, 2022
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1L8R
 | | Structure of the Retinal Determination Protein Dachshund Reveals a DNA-Binding Motif | | Descriptor: | Dachshund | | Authors: | Kim, S.S, Zhang, R, Braunstein, S.E, Joachimiak, A, Cvekl, A, Hegde, R.S. | | Deposit date: | 2002-03-21 | | Release date: | 2002-06-26 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (1.65 Å) | | Cite: | Structure of the retinal determination protein Dachshund reveals a DNA binding motif.
Structure, 10, 2002
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6HCQ
 | | Structure of the rabbit collided di-ribosome (collided monosome) | | Descriptor: | 18S ribosomal RNA, 28S ribosomal RNA, 40S ribosomal protein S12, ... | | Authors: | Juszkiewicz, S, Chandrasekaran, V, Lin, Z, Kraatz, S, Ramakrishnan, V, Hegde, R.S. | | Deposit date: | 2018-08-16 | | Release date: | 2018-10-17 | | Last modified: | 2018-11-14 | | Method: | ELECTRON MICROSCOPY (6.5 Å) | | Cite: | ZNF598 Is a Quality Control Sensor of Collided Ribosomes.
Mol. Cell, 72, 2018
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6HCM
 | | Structure of the rabbit collided di-ribosome (stalled monosome) | | Descriptor: | 18S ribosomal RNA, 28S ribosomal RNA, 40S ribosomal protein S12, ... | | Authors: | Juszkiewicz, S, Chandrasekaran, V, Lin, Z, Kraatz, S, Ramakrishnan, V, Hegde, R.S. | | Deposit date: | 2018-08-15 | | Release date: | 2018-10-17 | | Last modified: | 2024-05-15 | | Method: | ELECTRON MICROSCOPY (6.8 Å) | | Cite: | ZNF598 Is a Quality Control Sensor of Collided Ribosomes.
Mol. Cell, 72, 2018
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6HCJ
 | | Structure of the rabbit 80S ribosome on globin mRNA in the rotated state with A/P and P/E tRNAs | | Descriptor: | 18S ribosomal RNA, 28S ribosomal RNA, 40S ribosomal protein S12, ... | | Authors: | Juszkiewicz, S, Chandrasekaran, V, Lin, Z, Kraatz, S, Ramakrishnan, V, Hegde, R.S. | | Deposit date: | 2018-08-15 | | Release date: | 2018-10-17 | | Last modified: | 2018-11-14 | | Method: | ELECTRON MICROSCOPY (3.8 Å) | | Cite: | ZNF598 Is a Quality Control Sensor of Collided Ribosomes.
Mol. Cell, 72, 2018
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6HCF
 | | Structure of the rabbit 80S ribosome stalled on globin mRNA at the stop codon | | Descriptor: | 18S ribosomal RNA, 28S ribosomal RNA, 40S ribosomal protein S12, ... | | Authors: | Juszkiewicz, S, Chandrasekaran, V, Lin, Z, Kraatz, S, Ramakrishnan, V, Hegde, R.S. | | Deposit date: | 2018-08-14 | | Release date: | 2018-10-17 | | Last modified: | 2024-05-15 | | Method: | ELECTRON MICROSCOPY (3.9 Å) | | Cite: | ZNF598 Is a Quality Control Sensor of Collided Ribosomes.
Mol. Cell, 72, 2018
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5LZU
 | | Structure of the mammalian ribosomal termination complex with accommodated eRF1 | | Descriptor: | 18S ribosomal RNA, 28S ribosomal RNA, 40S ribosomal protein S12, ... | | Authors: | Shao, S, Murray, J, Brown, A, Taunton, J, Ramakrishnan, V, Hegde, R.S. | | Deposit date: | 2016-10-02 | | Release date: | 2016-11-30 | | Last modified: | 2024-05-15 | | Method: | ELECTRON MICROSCOPY (3.75 Å) | | Cite: | Decoding Mammalian Ribosome-mRNA States by Translational GTPase Complexes.
Cell, 167, 2016
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5LZS
 | | Structure of the mammalian ribosomal elongation complex with aminoacyl-tRNA, eEF1A, and didemnin B | | Descriptor: | (2~{S})-~{N}-[(2~{R})-1-[[(3~{S},6~{S},8~{S},12~{S},13~{R},16~{S},17~{R},20~{S},23~{S})-13-[(2~{S})-butan-2-yl]-20-[(4-methoxyphenyl)methyl]-6,17,21-trimethyl-3-(2-methylpropyl)-12-oxidanyl-2,5,7,10,15,19,22-heptakis(oxidanylidene)-8-propan-2-yl-9,18-dioxa-1,4,14,21-tetrazabicyclo[21.3.0]hexacosan-16-yl]amino]-4-methyl-1-oxidanylidene-pentan-2-yl]-~{N}-methyl-1-[(2~{S})-2-oxidanylpropanoyl]pyrrolidine-2-carboxamide, 18S ribosomal RNA, 28S ribosomal RNA, ... | | Authors: | Shao, S, Murray, J, Brown, A, Taunton, J, Ramakrishnan, V, Hegde, R.S. | | Deposit date: | 2016-10-02 | | Release date: | 2016-11-30 | | Last modified: | 2019-12-11 | | Method: | ELECTRON MICROSCOPY (3.31 Å) | | Cite: | Decoding Mammalian Ribosome-mRNA States by Translational GTPase Complexes.
Cell, 167, 2016
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5LZT
 | | Structure of the mammalian ribosomal termination complex with eRF1 and eRF3. | | Descriptor: | 18S ribosomal RNA, 28S ribosomal RNA, 5.8S ribosomal RNA, ... | | Authors: | Shao, S, Murray, J, Brown, A, Taunton, J, Ramakrishnan, V, Hegde, R.S. | | Deposit date: | 2016-10-02 | | Release date: | 2016-11-30 | | Last modified: | 2019-12-11 | | Method: | ELECTRON MICROSCOPY (3.65 Å) | | Cite: | Decoding Mammalian Ribosome-mRNA States by Translational GTPase Complexes.
Cell, 167, 2016
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5YTI
 | | Crystal structure of flagellar hook associated protein-3 (HAP-3: Q5ZW61_LEGPH) from Legionella pneumophila | | Descriptor: | CADMIUM ION, Flagellar hook associated protein type 3 FlgL | | Authors: | Lankipalli, S, Hegde, R.P, Dey, D, Almo, S.C, Ramagopal, U.A. | | Deposit date: | 2017-11-18 | | Release date: | 2018-01-17 | | Method: | X-RAY DIFFRACTION (2.75 Å) | | Cite: | Crystal structure of hook associated protein-3 (HAP-3: Q5ZW61_LEGPH) from Legionella pneumophila
To be published
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1JJ4
 | | Human papillomavirus type 18 E2 DNA-binding domain bound to its DNA target | | Descriptor: | E2 binding site DNA, Regulatory protein E2 | | Authors: | Kim, S.-S, Tam, J.K, Wang, A.F, Hegde, R.S. | | Deposit date: | 2001-07-03 | | Release date: | 2001-07-13 | | Last modified: | 2024-02-07 | | Method: | X-RAY DIFFRACTION (2.4 Å) | | Cite: | The structural basis of DNA target discrimination by papillomavirus E2 proteins.
J.Biol.Chem., 275, 2000
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3ZQ6
 | | ADP-ALF4 COMPLEX OF M. THERM. TRC40 | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, POTASSIUM ION, ... | | Authors: | Sherrill, J, Mariappan, M, Dominik, P, Hegde, R.S, Keenan, R.J. | | Deposit date: | 2011-06-08 | | Release date: | 2011-06-22 | | Last modified: | 2023-12-20 | | Method: | X-RAY DIFFRACTION (2.107 Å) | | Cite: | A Conserved Archaeal Pathway for Tail-Anchored Membrane Protein Insertion.
Traffic, 12, 2011
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2WOJ
 | | ADP-AlF4 complex of S. cerevisiae GET3 | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, ATPASE GET3, MAGNESIUM ION, ... | | Authors: | Mateja, A, Szlachcic, A, Downing, M.E, Dobosz, M, Mariappan, M, Hegde, R.S, Keenan, R.J. | | Deposit date: | 2009-07-26 | | Release date: | 2009-08-11 | | Last modified: | 2024-05-01 | | Method: | X-RAY DIFFRACTION (1.994 Å) | | Cite: | The Structural Basis of Tail-Anchored Membrane Protein Recognition by Get3.
Nature, 461, 2009
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1GRL
 | | THE CRYSTAL STRUCTURE OF THE BACTERIAL CHAPERONIN GROEL AT 2.8 ANGSTROMS | | Descriptor: | GROEL (HSP60 CLASS) | | Authors: | Braig, K, Otwinowski, Z, Hegde, R, Boisvert, D.C, Joachimiak, A, Horwich, A.L, Sigler, P.B. | | Deposit date: | 1995-03-07 | | Release date: | 1995-10-15 | | Last modified: | 2024-02-07 | | Method: | X-RAY DIFFRACTION (2.8 Å) | | Cite: | The crystal structure of the bacterial chaperonin GroEL at 2.8 A.
Nature, 371, 1994
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3ZS9
 | | S. cerevisiae Get3-ADP-AlF4- complex with a cytosolic Get2 fragment | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, ATPASE GET3, GOLGI TO ER TRAFFIC PROTEIN 2, ... | | Authors: | Mariappan, M, Mateja, A, Dobosz, M, Bove, E, Hegde, R.S, Keenan, R.J. | | Deposit date: | 2011-06-24 | | Release date: | 2011-09-07 | | Last modified: | 2023-12-20 | | Method: | X-RAY DIFFRACTION (2.095 Å) | | Cite: | The Mechanism of Membrane-Associated Steps in Tail-Anchored Protein Insertion.
Nature, 477, 2011
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3ZS8
 | | S. cerevisiae Get3 complexed with a cytosolic Get1 fragment | | Descriptor: | ATPASE GET3, GOLGI TO ER TRAFFIC PROTEIN 1, ZINC ION | | Authors: | Mariappan, M, Mateja, A, Dobosz, M, Bove, E, Hegde, R.S, Keenan, R.J. | | Deposit date: | 2011-06-24 | | Release date: | 2011-09-07 | | Last modified: | 2023-12-20 | | Method: | X-RAY DIFFRACTION (3 Å) | | Cite: | The Mechanism of Membrane-Associated Steps in Tail-Anchored Protein Insertion.
Nature, 477, 2011
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2WOO
 | | Nucleotide-free form of S. pombe Get3 | | Descriptor: | ATPASE GET3, ZINC ION | | Authors: | Mateja, A, Szlachcic, A, Downing, M.E, Dobosz, M, Mariappan, M, Hegde, R.S, Keenan, R.J. | | Deposit date: | 2009-07-27 | | Release date: | 2009-08-11 | | Last modified: | 2023-12-20 | | Method: | X-RAY DIFFRACTION (3.006 Å) | | Cite: | The Structural Basis of Tail-Anchored Membrane Protein Recognition by Get3.
Nature, 461, 2009
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5KZK
 | | Crystal Structure of rRNA methyltransferase from Sinorhizobium meliloti | | Descriptor: | COBALT (II) ION, Probable RNA methyltransferase, TrmH family, ... | | Authors: | Dey, D, Hegde, R.P, Almo, S.C, Ramakumar, S, Ramagopal, U.A, New York Structural Genomics Research Consortium (NYSGRC) | | Deposit date: | 2016-07-25 | | Release date: | 2017-08-02 | | Last modified: | 2019-11-20 | | Method: | X-RAY DIFFRACTION (2.28 Å) | | Cite: | Crystal Structure of rRNA methyltransferase from Sinorhizobium meliloti
To Be Published
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5L0Z
 | | Crystal Structure of AdoMet bound rRNA methyltransferase from Sinorhizobium meliloti | | Descriptor: | COBALT (II) ION, Probable RNA methyltransferase, TrmH family, ... | | Authors: | Dey, D, Hegde, R.P, Almo, S.C, Ramakumar, S, Ramagopal, U.A. | | Deposit date: | 2016-07-28 | | Release date: | 2017-08-02 | | Last modified: | 2019-11-20 | | Method: | X-RAY DIFFRACTION (2.9 Å) | | Cite: | Crystal Structure of AdoMet bound rRNA methyltransferase from Sinorhizobium meliloti
To Be Published
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5LZV
 | | Structure of the mammalian ribosomal termination complex with accommodated eRF1(AAQ) and ABCE1. | | Descriptor: | 18S ribosomal RNA, 28S ribosomal RNA, 5.8S ribosomal RNA, ... | | Authors: | Shao, S, Murray, J, Brown, A, Taunton, J, Ramakrishnan, V, Hegde, R.S. | | Deposit date: | 2016-10-02 | | Release date: | 2016-11-30 | | Last modified: | 2024-05-15 | | Method: | ELECTRON MICROSCOPY (3.35 Å) | | Cite: | Decoding Mammalian Ribosome-mRNA States by Translational GTPase Complexes.
Cell, 167, 2016
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