1IEF
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![BU of 1ief by Molmil](/molmil-images/mine/1ief) | CRYSTAL STRUCTURE OF THE CATALYTIC SITE MUTANT S134A OF THE HUMAN CYTOMEGALOVIRUS PROTEASE | Descriptor: | CAPSID PROTEIN P40: ASSEMBLIN PROTEASE | Authors: | Khayat, R, Batra, R, Massariol, M.J, Lagace, L, Tong, L. | Deposit date: | 2001-04-09 | Release date: | 2001-06-06 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Investigating the role of histidine 157 in the catalytic activity of human cytomegalovirus protease. Biochemistry, 40, 2001
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1NJT
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![BU of 1njt by Molmil](/molmil-images/mine/1njt) | COMPLEX STRUCTURE OF HCMV PROTEASE AND A PEPTIDOMIMETIC INHIBITOR | Descriptor: | CHLORIDE ION, Capsid protein P40, Peptidomimetic Inhibitor | Authors: | Khayat, R, Batra, R, Qian, C, Halmos, T, Bailey, M, Tong, L. | Deposit date: | 2003-01-02 | Release date: | 2003-02-11 | Last modified: | 2021-10-27 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Structural and Biochemical Studies of Inhibitor Binding to Human Cytomegalovirus Protease Biochemistry, 42, 2003
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1IED
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![BU of 1ied by Molmil](/molmil-images/mine/1ied) | CRYSTAL STRUCTURE OF THE CATALYTIC SITE MUTANT (H157E) OF THE HUMAN CYTOMEGALOVIRUS PROTEASE | Descriptor: | CAPSID PROTEIN P40: ASSEMBLIN PROTEASE | Authors: | Khayat, R, Batra, R, Massariol, M.J, Lagace, L, Tong, L. | Deposit date: | 2001-04-09 | Release date: | 2001-06-06 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Investigating the role of histidine 157 in the catalytic activity of human cytomegalovirus protease. Biochemistry, 40, 2001
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6E2R
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![BU of 6e2r by Molmil](/molmil-images/mine/6e2r) | Mechanism of cellular recognition by PCV2 | Descriptor: | Capsid protein of PCV2 | Authors: | Khayat, R, Dhindwal, S. | Deposit date: | 2018-07-12 | Release date: | 2018-12-26 | Last modified: | 2024-03-20 | Method: | ELECTRON MICROSCOPY (2.8 Å) | Cite: | Porcine Circovirus 2 Uses a Multitude of Weak Binding Sites To Interact with Heparan Sulfate, and the Interactions Do Not Follow the Symmetry of the Capsid. J.Virol., 93, 2019
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6E32
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![BU of 6e32 by Molmil](/molmil-images/mine/6e32) | Capsid protein of PCV2 with N,O6-DISULFO-GLUCOSAMINE | Descriptor: | 2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-2-O-sulfo-alpha-L-idopyranuronic acid-(1-4)-2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-2-O-sulfo-alpha-L-idopyranuronic acid-(1-4)-2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose, Capsid protein of PCV2 | Authors: | Khayat, R, Dhindwal, S. | Deposit date: | 2018-07-13 | Release date: | 2018-12-26 | Last modified: | 2024-03-13 | Method: | ELECTRON MICROSCOPY (3.4 Å) | Cite: | Porcine Circovirus 2 Uses a Multitude of Weak Binding Sites To Interact with Heparan Sulfate, and the Interactions Do Not Follow the Symmetry of the Capsid. J.Virol., 93, 2019
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6E34
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![BU of 6e34 by Molmil](/molmil-images/mine/6e34) | Capsid protein of PCV2 with N,O6-DISULFO-GLUCOSAMINE and 2-O-sulfo-alpha-L-idopyranuronic acid | Descriptor: | 2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-2-O-sulfo-alpha-L-idopyranuronic acid-(1-4)-2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose, Capsid protein of PCV2 | Authors: | Khayat, R, Dhindwal, S. | Deposit date: | 2018-07-13 | Release date: | 2018-12-26 | Last modified: | 2024-03-13 | Method: | ELECTRON MICROSCOPY (3.6 Å) | Cite: | Porcine Circovirus 2 Uses a Multitude of Weak Binding Sites To Interact with Heparan Sulfate, and the Interactions Do Not Follow the Symmetry of the Capsid. J.Virol., 93, 2019
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6E39
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![BU of 6e39 by Molmil](/molmil-images/mine/6e39) | |
6E30
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![BU of 6e30 by Molmil](/molmil-images/mine/6e30) | Mechanism of cellular recognition by PCV2 | Descriptor: | 2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-2-O-sulfo-alpha-L-idopyranuronic acid-(1-4)-2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-2-O-sulfo-alpha-L-idopyranuronic acid-(1-4)-2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose, Capsid protein of PCV2 | Authors: | Khayat, R, Dhindwal, S. | Deposit date: | 2018-07-12 | Release date: | 2018-12-26 | Last modified: | 2024-03-13 | Method: | ELECTRON MICROSCOPY (3.5 Å) | Cite: | Porcine Circovirus 2 Uses a Multitude of Weak Binding Sites To Interact with Heparan Sulfate, and the Interactions Do Not Follow the Symmetry of the Capsid. J.Virol., 93, 2019
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1NKM
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![BU of 1nkm by Molmil](/molmil-images/mine/1nkm) | Complex structure of HCMV Protease and a peptidomimetic inhibitor | Descriptor: | Assemblin, N-(6-aminohexanoyl)-3-methyl-L-valyl-3-methyl-L-valyl-N~1~-[(2S,3S)-3-hydroxy-4-oxo-4-{[(1R)-1-phenylpropyl]amino}butan-2-yl]-N~4~,N~4~-dimethyl-L-aspartamide | Authors: | Khayat, R, Batra, R, Qian, C, Halmos, T, Bailey, M, Tong, L. | Deposit date: | 2003-01-03 | Release date: | 2003-02-11 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Structural and Biochemical Studies of Inhibitor Binding to Human Cytomegalovirus Protease Biochemistry, 42, 2003
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1NKK
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![BU of 1nkk by Molmil](/molmil-images/mine/1nkk) | COMPLEX STRUCTURE OF HCMV PROTEASE AND A PEPTIDOMIMETIC INHIBITOR | Descriptor: | Capsid protein P40, Peptidomimetic inhibitor | Authors: | Khayat, R, Batra, R, Qian, C, Halmos, T, Bailey, M, Tong, L. | Deposit date: | 2003-01-03 | Release date: | 2003-02-11 | Last modified: | 2021-10-27 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Structural and Biochemical Studies of Inhibitor Binding to Human Cytomegalovirus Protease Biochemistry, 42, 2003
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1NJU
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![BU of 1nju by Molmil](/molmil-images/mine/1nju) | Complex structure of HCMV Protease and a peptidomimetic inhibitor | Descriptor: | Assemblin, N-(6-aminohexanoyl)-3-methyl-L-valyl-3-methyl-L-valyl-N~1~-[(2S,3S)-3-hydroxy-4-oxo-4-{[(1R)-1-phenylpropyl]amino}butan-2-yl]-N~4~,N~4~-dimethyl-L-aspartamide | Authors: | Khayat, R, Batra, R, Qian, C, Halmos, T, Bailey, M, Tong, L. | Deposit date: | 2003-01-02 | Release date: | 2003-02-11 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Structural and Biochemical Studies of Inhibitor Binding to Human Cytomegalovirus Protease Biochemistry, 42, 2003
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6DZU
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![BU of 6dzu by Molmil](/molmil-images/mine/6dzu) | |
6E2X
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![BU of 6e2x by Molmil](/molmil-images/mine/6e2x) | Mechanism of cellular recognition by PCV2 | Descriptor: | 2-O-sulfo-alpha-L-idopyranuronic acid-(1-4)-2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-2-O-sulfo-alpha-L-idopyranuronic acid-(1-4)-2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose, Capsid protein of PCV2 | Authors: | Khayat, R, Dhindwal, S. | Deposit date: | 2018-07-12 | Release date: | 2018-12-26 | Last modified: | 2024-03-13 | Method: | ELECTRON MICROSCOPY (3.5 Å) | Cite: | Porcine Circovirus 2 Uses a Multitude of Weak Binding Sites To Interact with Heparan Sulfate, and the Interactions Do Not Follow the Symmetry of the Capsid. J.Virol., 93, 2019
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6E2Z
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![BU of 6e2z by Molmil](/molmil-images/mine/6e2z) | Mechanism of cellular recognition by PCV2 | Descriptor: | 2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-2-O-sulfo-alpha-L-idopyranuronic acid-(1-4)-2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose, Capsid protein of PCV2 | Authors: | Khayat, R, Dhindwal, S. | Deposit date: | 2018-07-12 | Release date: | 2018-12-26 | Last modified: | 2024-03-13 | Method: | ELECTRON MICROSCOPY (3.4 Å) | Cite: | Porcine Circovirus 2 Uses a Multitude of Weak Binding Sites To Interact with Heparan Sulfate, and the Interactions Do Not Follow the Symmetry of the Capsid. J.Virol., 93, 2019
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3R0R
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![BU of 3r0r by Molmil](/molmil-images/mine/3r0r) | |
7LAS
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![BU of 7las by Molmil](/molmil-images/mine/7las) | Cryo-EM structure of PCV2 Replicase bound to ssDNA | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, ATP-dependent helicase Rep, DNA (5'-D(P*GP*AP*TP*CP*GP*AP*TP*CP*GP*A)-3'), ... | Authors: | Khayat, R. | Deposit date: | 2021-01-06 | Release date: | 2021-08-25 | Last modified: | 2024-05-29 | Method: | ELECTRON MICROSCOPY (4.4 Å) | Cite: | Mechanism of DNA Interaction and Translocation by the Replicase of a Circular Rep-Encoding Single-Stranded DNA Virus. Mbio, 12, 2021
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7LAR
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![BU of 7lar by Molmil](/molmil-images/mine/7lar) | Cryo-EM structure of PCV2 Replicase bound to ssDNA | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, ATP-dependent helicase Rep, DNA (5'-D(P*TP*TP*TP*TP*TP*T)-3'), ... | Authors: | Khayat, R. | Deposit date: | 2021-01-06 | Release date: | 2021-08-25 | Last modified: | 2024-05-29 | Method: | ELECTRON MICROSCOPY (3.8 Å) | Cite: | Mechanism of DNA Interaction and Translocation by the Replicase of a Circular Rep-Encoding Single-Stranded DNA Virus. Mbio, 12, 2021
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1NXH
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![BU of 1nxh by Molmil](/molmil-images/mine/1nxh) | X-RAY STRUCTURE: NORTHEAST STRUCTURAL GENOMICS CONSORTIUM TARGET TT87 | Descriptor: | MTH396 protein | Authors: | Khayat, R, Savchenko, A, Edwards, A, Arowsmith, C, Tong, L, Northeast Structural Genomics Consortium (NESG) | Deposit date: | 2003-02-10 | Release date: | 2004-02-24 | Last modified: | 2017-10-11 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | X-RAY STRUCTURE OF MTH396 To be Published
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2BBD
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![BU of 2bbd by Molmil](/molmil-images/mine/2bbd) | Crystal Structure of the STIV MCP | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, coat protein | Authors: | Khayat, R. | Deposit date: | 2005-10-17 | Release date: | 2005-12-06 | Last modified: | 2017-10-18 | Method: | X-RAY DIFFRACTION (2.04 Å) | Cite: | Structure of an archaeal virus capsid protein reveals a common ancestry to eukaryotic and bacterial viruses. Proc.Natl.Acad.Sci.Usa, 102, 2005
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2XPH
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![BU of 2xph by Molmil](/molmil-images/mine/2xph) | Crystal structure of human SENP1 with the bound cobalt | Descriptor: | COBALT (II) ION, GLYCEROL, SENTRIN-SPECIFIC PROTEASE 1 | Authors: | Rimsa, V, Eadsforth, T, Hay, R.T, Hunter, W.N. | Deposit date: | 2010-08-26 | Release date: | 2010-09-08 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | The Role of Co2+ in the Crystallization of Human Senp1 and Comments on the Limitations of Automated Refinement Protocols Acta Crystallogr.,Sect.F, 67, 2011
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1A45
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![BU of 1a45 by Molmil](/molmil-images/mine/1a45) | GAMMAF CRYSTALLIN FROM BOVINE LENS | Descriptor: | GAMMAF CRYSTALLIN | Authors: | Norledge, B.V, Hay, R, Bateman, O.A, Slingsby, C, White, H.E, Moss, D.S, Lindley, P.F, Driessen, H.P.C. | Deposit date: | 1998-02-10 | Release date: | 1998-06-17 | Last modified: | 2024-05-22 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Towards a molecular understanding of phase separation in the lens: a comparison of the X-ray structures of two high Tc gamma-crystallins, gammaE and gammaF, with two low Tc gamma-crystallins, gammaB and gammaD. Exp.Eye Res., 65, 1997
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1A5D
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![BU of 1a5d by Molmil](/molmil-images/mine/1a5d) | GAMMAE CRYSTALLIN FROM RAT LENS | Descriptor: | GAMMAE CRYSTALLIN | Authors: | Norledge, B.V, Hay, R, Bateman, O.A, Slingsby, C, Driessen, H.P.C. | Deposit date: | 1998-02-12 | Release date: | 1998-05-27 | Last modified: | 2024-05-22 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Towards a molecular understanding of phase separation in the lens: a comparison of the X-ray structures of two high Tc gamma-crystallins, gammaE and gammaF, with two low Tc gamma-crystallins, gammaB and gammaD. Exp.Eye Res., 65, 1997
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1ELP
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![BU of 1elp by Molmil](/molmil-images/mine/1elp) | GAMMA-D CRYSTALLIN STRUCTURE AT 1.95 A RESOLUTION | Descriptor: | GAMMA-D CRYSTALLIN | Authors: | Chirgadze, Yu.N, Driessen, H.P.C, Wright, G, Slingsby, C, Hay, R.E, Lindley, P.F. | Deposit date: | 1995-12-20 | Release date: | 1996-06-10 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | Structure of bovine eye lens gammaD (gammaIIIb)-crystallin at 1.95 A. Acta Crystallogr.,Sect.D, 52, 1996
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2XEU
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![BU of 2xeu by Molmil](/molmil-images/mine/2xeu) | Ring domain | Descriptor: | RING FINGER PROTEIN 4, SULFATE ION, ZINC ION, ... | Authors: | Plechanovova, A, McMahon, S.A, Johnson, K.A, Navratilova, I, Naismith, J.H, Hay, R.T. | Deposit date: | 2010-05-18 | Release date: | 2010-07-28 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | Mechanism of Ubiquitylation by Dimeric Ring Ligase Rnf4 Nat.Struct.Mol.Biol., 18, 2011
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4AP4
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![BU of 4ap4 by Molmil](/molmil-images/mine/4ap4) | Rnf4 - ubch5a - ubiquitin heterotrimeric complex | Descriptor: | E3 UBIQUITIN LIGASE RNF4, UBIQUITIN C, UBIQUITIN-CONJUGATING ENZYME E2 D1, ... | Authors: | Plechanovova, A, Hay, R.T, Tatham, M.H, Jaffray, E, Naismith, J.H. | Deposit date: | 2012-03-30 | Release date: | 2012-07-25 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.21 Å) | Cite: | Structure of a Ring E3 Ligase and Ubiquitin-Loaded E2 Primed for Catalysis Nature, 489, 2012
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