4CBY
 
 | | Design, synthesis, and biological evaluation of potent and selective Class IIa HDAC inhibitors as a potential therapy for Huntington's disease | | 分子名称: | (1R,2R,3R)-2-[4-(1,3-oxazol-5-yl)phenyl]-N-oxidanyl-3-phenyl-cyclopropane-1-carboxamide, HISTONE DEACETYLASE 4, SODIUM ION, ... | | 著者 | Burli, R.W, Luckhurst, C.A, Aziz, O, Matthews, K.L, Yates, D, Lyons, K.A, Beconi, M, McAllister, G, Breccia, P, Stott, A.J, Penrose, S.D, Wall, M, Lamers, M, Leonard, P, Mueller, I, Richardson, C.M, Jarvis, R, Stones, L, Hughes, S, Wishart, G, Haughan, A.F, O'Connell, C, Mead, T, McNeil, H, Vann, J, Mangette, J, Maillard, M, Beaumont, V, Munoz-Sanjuan, I, Dominguez, C. | | 登録日 | 2013-10-17 | | 公開日 | 2013-12-11 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (2.72 Å) | | 主引用文献 | Design, synthesis, and biological evaluation of potent and selective class IIa histone deacetylase (HDAC) inhibitors as a potential therapy for Huntington's disease.
J. Med. Chem., 56, 2013
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4E3C
 | | X-ray crystal structure of human IKK2 in an active conformation | | 分子名称: | Inhibitor of nuclear factor kappa-B kinase subunit beta | | 著者 | Polley, S, Huang, D.B, Hauenstein, A.V, Ghosh, G, Huxford, T. | | 登録日 | 2012-03-09 | | 公開日 | 2013-06-19 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (3.98 Å) | | 主引用文献 | X-ray crystal structure of human IKK2 in an active conformation
Plos.Biol., 2013
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5WUY
 | | Crystal structure of chorismate synthase from Acinetobacter baumannii at 2.50A resolution | | 分子名称: | Chorismate synthase | | 著者 | Iqbal, N, Chaudhary, A, Shukla, K.P, Kaur, P, Sharma, S, Singh, T.P. | | 登録日 | 2016-12-21 | | 公開日 | 2017-01-18 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Crystal structure of chorismate synthase from Acinetobacter baumannii at 2.50A resolution
To Be Published
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4NSB
 | | Crystal structure of the complex of signaling glycoprotein, SPB-40 and N-acetyl salicylic acid at 3.05 A resolution | | 分子名称: | 2-(ACETYLOXY)BENZOIC ACID, 2-acetamido-2-deoxy-beta-D-glucopyranose, Chitinase-3-like protein 1 | | 著者 | Yamini, S, Chaudhary, A, Sinha, M, Kaur, P, Sharma, S, Singh, T.P. | | 登録日 | 2013-11-28 | | 公開日 | 2013-12-11 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (3.05 Å) | | 主引用文献 | Crystal structure of the complex of signaling glycoprotein, SPB-40 and N-acetyl salicylic acid at 3.05 A resolution
To be Published
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4AN7
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4BK4
 | | crystal structure of the human EphA4 ectodomain | | 分子名称: | EPHRIN TYPE-A RECEPTOR 4 | | 著者 | Seiradake, E, Schaupp, A, del Toro Ruiz, D, Kaufmann, R, Mitakidis, N, Harlos, K, Aricescu, A.R, Klein, R, Jones, E.Y. | | 登録日 | 2013-04-22 | | 公開日 | 2013-07-03 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (3.65 Å) | | 主引用文献 | Structurally Encoded Intraclass Differences in Epha Clusters Drive Distinct Cell Responses
Nat.Struct.Mol.Biol., 20, 2013
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3GE8
 | | Toluene 4-monooxygenase HD T201A diferric, resting state complex | | 分子名称: | ACETATE ION, FE (III) ION, Toluene-4-monooxygenase system protein A, ... | | 著者 | Elsen, N.L, Bailey, L.J, Hauser, A.D, Fox, B.G. | | 登録日 | 2009-02-25 | | 公開日 | 2009-07-28 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (2.19 Å) | | 主引用文献 | Role for threonine 201 in the catalytic cycle of the soluble diiron hydroxylase toluene 4-monooxygenase.
Biochemistry, 48, 2009
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5Z9A
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3IPS
 | | X-ray structure of benzisoxazole synthetic agonist bound to the LXR-alpha | | 分子名称: | Nuclear receptor coactivator 1, Oxysterols receptor LXR-alpha, SULFATE ION, ... | | 著者 | Fradera, X, Vu, D, Nimz, O, Skene, R, Hosfield, D, Wijnands, R, Cooke, A.J, Haunso, A, King, A, Bennet, D.J, McGuire, R, Uitdehaag, J.C.M. | | 登録日 | 2009-08-18 | | 公開日 | 2010-06-02 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (2.26 Å) | | 主引用文献 | X-ray structures of the LXRalpha LBD in its homodimeric form and implications for heterodimer signaling.
J.Mol.Biol., 399, 2010
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4MTV
 | | Crystal structure of the complex of Buffalo Signalling Glycoprotein with pentasaccharide at 2.8A resolution | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Chitinase-3-like protein 1 | | 著者 | Shukla, P.K, Chaudhary, A, Singh, A.K, Sinha, M, Kaur, P, Sharma, S, Singh, T.P. | | 登録日 | 2013-09-20 | | 公開日 | 2013-10-16 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Crystal structure of the complex of Buffalo Signalling Glycoprotein with pentasaccharide at 2.8A resolution
To be Published
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1TBX
 | | Crystal structure of SSV1 F-93 | | 分子名称: | Hypothetical 11.0 kDa protein | | 著者 | Kraft, P, Oeckinghaus, A, Kummel, D, Gauss, G.H, Wiedenheft, B, Young, M, Lawrence, C.M. | | 登録日 | 2004-05-20 | | 公開日 | 2004-07-13 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | Crystal structure of F-93 from Sulfolobus spindle-shaped virus 1, a winged-helix DNA binding protein.
J.Virol., 78, 2004
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4OB9
 | | Crystal structure of chorismate synthase from Acinetobacter baumannii at 2.50A resolution | | 分子名称: | Chorismate synthase | | 著者 | Shukla, P.K, Chaudhary, A, Singh, N, Sinha, M, Bhushan, A, Kaur, P, Sharma, S, Singh, T.P. | | 登録日 | 2014-01-07 | | 公開日 | 2014-01-22 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Crystal structure of chorismate synthase from Acinetobacter baumannii at 2.50A resolution
To be Published
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3IPU
 | | X-ray structure of benzisoxazole urea synthetic agonist bound to the LXR-alpha | | 分子名称: | 4-{[methyl(3-{[7-propyl-3-(trifluoromethyl)-1,2-benzisoxazol-6-yl]oxy}propyl)carbamoyl]amino}benzoic acid, Nuclear receptor coactivator 1, Oxysterols receptor LXR-alpha, ... | | 著者 | Fradera, X, Vu, D, Nimz, O, Skene, R, Hosfield, D, Wijnands, R, Cooke, A.J, Haunso, A, King, A, Bennet, D.J, McGuire, R, Uitdehaag, J.C.M. | | 登録日 | 2009-08-18 | | 公開日 | 2010-06-02 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | X-ray structures of the LXRalpha LBD in its homodimeric form and implications for heterodimer signaling.
J.Mol.Biol., 399, 2010
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4CDN
 | | Crystal structure of M. mazei photolyase with its in vivo reconstituted 8-HDF antenna chromophore | | 分子名称: | 1-deoxy-1-(8-hydroxy-2,4-dioxo-3,4-dihydropyrimido[4,5-b]quinolin-10(2H)-yl)-D-ribitol, DEOXYRIBODIPYRIMIDINE PHOTOLYASE, DI(HYDROXYETHYL)ETHER, ... | | 著者 | Kiontke, S, Batschauer, A, Essen, L.-O. | | 登録日 | 2013-11-01 | | 公開日 | 2014-05-21 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Structural and Evolutionary Aspects of Antenna Chromophore Usage by Class II Photolyases.
J.Biol.Chem., 289, 2014
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4ML4
 | | Crystal structure of the complex of signaling glycoprotein from buffalo (SPB-40) with tetrahydropyran at 2.5 A resolution | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Chitinase-3-like protein 1, TETRAHYDROPYRAN | | 著者 | Yamini, S, Chaudhary, A, Sinha, M, Kaur, P, Sharma, S, Singh, T.P. | | 登録日 | 2013-09-06 | | 公開日 | 2013-09-25 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Crystal structure of the complex of signaling glycoprotein from buffalo (SPB-40) with tetrahydropyran at 2.5 A resolution
To be Published
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4BK5
 | | crystal structure of the human EphA4 ectodomain in complex with human ephrin A5 (amine-methylated sample) | | 分子名称: | EPHRIN TYPE-A RECEPTOR 4, EPHRIN-A5 | | 著者 | Seiradake, E, Schaupp, A, del Toro Ruiz, D, Kaufmann, R, Mitakidis, N, Harlos, K, Aricescu, A.R, Klein, R, Jones, E.Y. | | 登録日 | 2013-04-22 | | 公開日 | 2013-07-03 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (4 Å) | | 主引用文献 | Structurally Encoded Intraclass Differences in Epha Clusters Drive Distinct Cell Responses
Nat.Struct.Mol.Biol., 20, 2013
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4BKF
 | | crystal structure of the human EphA4 ectodomain in complex with human ephrinB3 | | 分子名称: | EPHRIN TYPE-A RECEPTOR 4, EPHRIN-B3 | | 著者 | Seiradake, E, Schaupp, A, del Toro Ruiz, D, Kaufmann, R, Mitakidis, N, Harlos, K, Aricescu, A.R, Klein, R, Jones, E.Y. | | 登録日 | 2013-04-24 | | 公開日 | 2013-07-03 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (4.65 Å) | | 主引用文献 | Structurally Encoded Intraclass Differences in Epha Clusters Drive Distinct Cell Responses
Nat.Struct.Mol.Biol., 20, 2013
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4MPK
 | | Crystal structure of the complex of buffalo signaling protein SPB-40 with N-acetylglucosamine at 2.65 A resolution | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Chitinase-3-like protein 1, GLYCEROL | | 著者 | Yamini, S, Chaudhary, A, Sinha, M, Kaur, P, Sharma, S, Singh, T.P. | | 登録日 | 2013-09-13 | | 公開日 | 2013-11-06 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (2.65 Å) | | 主引用文献 | Crystal structure of the complex of buffalo signaling protein SPB-40 with N-acetylglucosamine at 2.65 A resolution
To be Published
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3IPQ
 | | X-ray structure of GW3965 synthetic agonist bound to the LXR-alpha | | 分子名称: | Nuclear receptor coactivator 1, Oxysterols receptor LXR-alpha, SULFATE ION, ... | | 著者 | Fradera, X, Vu, D, Nimz, O, Skene, R, Hosfield, D, Wijnands, R, Cooke, A.J, Haunso, A, King, A, Bennet, D.J, McGuire, R, Uitdehaag, J.C.M. | | 登録日 | 2009-08-18 | | 公開日 | 2010-06-02 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | X-ray structures of the LXRalpha LBD in its homodimeric form and implications for heterodimer signaling.
J.Mol.Biol., 399, 2010
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2W84
 | | Structure of Pex14 in complex with Pex5 | | 分子名称: | PEROXISOMAL MEMBRANE PROTEIN PEX14, PEROXISOMAL TARGETING SIGNAL 1 RECEPTOR | | 著者 | Neufeld, C, Filipp, F.V, Simon, B, Neuhaus, A, Schueller, N, David, C, Kooshapur, H, Madl, T, Erdmann, R, Schliebs, W, Wilmanns, M, Sattler, M. | | 登録日 | 2009-01-09 | | 公開日 | 2009-02-17 | | 最終更新日 | 2024-05-15 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Structural basis for competitive interactions of Pex14 with the import receptors Pex5 and Pex19.
EMBO J., 28, 2009
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2WL7
 | | Crystal structure of the PSD93 PDZ1 domain | | 分子名称: | CHLORIDE ION, DISKS LARGE HOMOLOG 2, SULFATE ION | | 著者 | Fiorentini, M, Kallehauge, A, Kristensen, O, Kastrup, J.S, Gajhede, M. | | 登録日 | 2009-06-22 | | 公開日 | 2010-01-19 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (2.028 Å) | | 主引用文献 | Structure of the First Pdz Domain of Human Psd-93.
Acta Crystallogr.,Sect.F, 65, 2009
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8A5R
 | | Crystal structure of light-activated DNA-binding protein EL222 from Erythrobacter litoralis crystallized and measured in dark. | | 分子名称: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CHLORIDE ION, FLAVIN MONONUCLEOTIDE, ... | | 著者 | Koval, T, Chaudhari, A, Fuertes, G, Andersson, I, Dohnalek, J. | | 登録日 | 2022-06-15 | | 公開日 | 2023-07-05 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | | 主引用文献 | EL222 from Erythrobacter litoralis.
To Be Published
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8A5S
 | | Crystal structure of light-activated DNA-binding protein EL222 from Erythrobacter litoralis crystallized in dark, measured illuminated. | | 分子名称: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CHLORIDE ION, FLAVIN MONONUCLEOTIDE, ... | | 著者 | Koval, T, Chaudhari, A, Fuertes, G, Andersson, I, Dohnalek, J. | | 登録日 | 2022-06-15 | | 公開日 | 2023-07-05 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | | 主引用文献 | EL222 from Erythrobacter litoralis.
To Be Published
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4BKA
 | | crystal structure of the human EphA4 ectodomain in complex with human ephrin A5 | | 分子名称: | EPHRIN TYPE-A RECEPTOR 4, EPHRIN-A5 | | 著者 | Seiradake, E, Schaupp, A, del Toro Ruiz, D, Kaufmann, R, Mitakidis, N, Harlos, K, Aricescu, A.R, Klein, R, Jones, E.Y. | | 登録日 | 2013-04-23 | | 公開日 | 2013-07-03 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (5.3 Å) | | 主引用文献 | Structurally Encoded Intraclass Differences in Epha Clusters Drive Distinct Cell Responses
Nat.Struct.Mol.Biol., 20, 2013
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4CDM
 | | Crystal structure of M. mazei photolyase soaked with synthetic 8-HDF | | 分子名称: | 1-deoxy-1-(8-hydroxy-2,4-dioxo-3,4-dihydropyrimido[4,5-b]quinolin-10(2H)-yl)-D-ribitol, DEOXYRIBODIPYRIMIDINE PHOTOLYASE, FLAVIN-ADENINE DINUCLEOTIDE, ... | | 著者 | Kiontke, S, Batschauer, A, Essen, L.-O. | | 登録日 | 2013-11-01 | | 公開日 | 2014-05-21 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | Structural and Evolutionary Aspects of Antenna Chromophore Usage by Class II Photolyases.
J.Biol.Chem., 289, 2014
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