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PDB: 264 件

7T8E
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G93A mutant of human SOD1 in P21 space group
分子名称: ACETATE ION, SULFATE ION, Superoxide dismutase [Cu-Zn], ...
著者Amporndanai, K, Hasnain, S.S.
登録日2021-12-16
公開日2023-01-25
最終更新日2024-10-09
実験手法X-RAY DIFFRACTION (1.4 Å)
主引用文献Ebselen analogues delay disease onset and its course in fALS by on-target SOD-1 engagement.
Sci Rep, 14, 2024
7T8H
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G93A mutant of human SOD1 bound with MR6-26-2 in P21 space group
分子名称: ACETATE ION, SULFATE ION, Superoxide dismutase [Cu-Zn], ...
著者Amporndanai, K, Hasnain, S.S.
登録日2021-12-16
公開日2023-01-25
最終更新日2024-06-05
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Ebselen analogues delay disease onset and its course in fALS by on-target SOD-1 engagement.
Sci Rep, 14, 2024
2IWF
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Resting form of pink nitrous oxide reductase from Achromobacter Cycloclastes
分子名称: (MU-4-SULFIDO)-TETRA-NUCLEAR COPPER ION, CALCIUM ION, CHLORIDE ION, ...
著者Paraskevopoulos, K, Antonyuk, S.V, Sawers, R.G, Eady, R.R, Hasnain, S.S.
登録日2006-06-29
公開日2006-08-16
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (1.86 Å)
主引用文献Insight Into Catalysis of Nitrous Oxide Reductase from High-Resolution Structures of Resting and Inhibitor-Bound Enzyme from Achromobacter Cycloclastes.
J.Mol.Biol., 362, 2006
2IWK
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Inhibitor-bound form of nitrous oxide reductase from Achromobacter Cycloclastes at 1.7 Angstrom resolution
分子名称: (MU-4-SULFIDO)-TETRA-NUCLEAR COPPER ION, CALCIUM ION, CHLORIDE ION, ...
著者Paraskevopoulos, K, Antonyuk, S.V, Sawers, R.G, Eady, R.R, Hasnain, S.S.
登録日2006-06-30
公開日2006-08-16
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Insight Into Catalysis of Nitrous Oxide Reductase from High-Resolution Structures of Resting and Inhibitor-Bound Enzyme from Achromobacter Cycloclastes.
J.Mol.Biol., 362, 2006
2JLP
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Crystal structure of human extracellular copper-zinc superoxide dismutase.
分子名称: COPPER (II) ION, EXTRACELLULAR SUPEROXIDE DISMUTASE (CU-ZN), THIOCYANATE ION, ...
著者Antonyuk, S.V, Strange, R.W, Marklund, S.L, Hasnain, S.S.
登録日2008-09-14
公開日2009-03-17
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献The Structure of Human Extracellular Copper-Zinc Superoxide Dismutase at 1.7 A Resolution: Insights Into Heparin and Collagen Binding.
J.Mol.Biol., 388, 2009
2JFC
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M144L mutant of Nitrite Reductase from Alcaligenes xylosoxidans in space group P212121
分子名称: CHLORIDE ION, COPPER (II) ION, DISSIMILATORY COPPER-CONTAINING NITRITE REDUCTASE
著者Paraskevopoulos, K, Hough, M.A, Sawers, R.G, Eady, R.R, Hasnain, S.S.
登録日2007-01-31
公開日2007-05-29
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献The Structure of the met144Leu Mutant of Copper Nitrite Reductase from Alcaligenes Xylosoxidans Provides the First Glimpse of a Protein-Protein Complex with Azurin II.
J.Biol.Inorg.Chem., 12, 2007
2JHO
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Cyanomet Sperm Whale Myoglobin at 1.4A resolution
分子名称: CYANIDE ION, Myoglobin, PROTOPORPHYRIN IX CONTAINING FE, ...
著者Arcovito, A, Benfatto, M, Cianci, M, Hasnain, S.S, Nienhaus, K, Nienhaus, G.U, Savino, C, Strange, R.W, Vallone, B, Della Longa, S.
登録日2007-02-23
公開日2007-04-03
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (1.4 Å)
主引用文献X-ray structure analysis of a metalloprotein with enhanced active-site resolution using in situ x-ray absorption near edge structure spectroscopy.
Proc. Natl. Acad. Sci. U.S.A., 104, 2007
7R3V
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Crystal structure of bovine Cytochrome bc1 in complex with inhibitor CK-2-67.
分子名称: 1,2-DIHEXANOYL-SN-GLYCERO-3-PHOSPHOETHANOLAMINE, 1,2-DIMYRISTOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine, ...
著者Pinthong, N, Amporndanai, K, O'Neill, P.M, Hasnain, S.S, Antonyuk, S.
登録日2022-02-07
公開日2022-08-10
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献Targeting the Ubiquinol-Reduction (Q i ) Site of the Mitochondrial Cytochrome bc 1 Complex for the Development of Next Generation Quinolone Antimalarials.
Biology (Basel), 11, 2022
2XXG
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STRUCTURE OF THE N90S MUTANT OF NITRITE REDUCTASE FROM ALCALIGENES XYLOSOXIDANS
分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, COPPER (II) ION, DI(HYDROXYETHYL)ETHER, ...
著者Hough, M.A, Eady, R.R, Hasnain, S.S.
登録日2010-11-10
公開日2011-05-18
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Identification of the Proton Channel to the Active Site Type 2 Cu Centre of Nitrite Reductase: Structural and Enzymatic Properties of the His254Phe and Asn90Ser Mutants
Biochemistry, 47, 2008
2XXF
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Cu metallated H254F mutant of nitrite reductase
分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, COPPER (II) ION, DI(HYDROXYETHYL)ETHER, ...
著者Hough, M.A, Eady, R.R, Hasnain, S.S.
登録日2010-11-10
公開日2011-05-18
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Proton-Coupled Electron Transfer in the Catalytic Cycle of Alcaligenes Xylosoxidans Copper-Dependent Nitrite Reductase.
Biochemistry, 50, 2011
2YLI
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RECOMBINANT NATIVE CYTOCHROME C PRIME FROM ALCALIGENES XYLOSOXIDANS IN ITS FERROUS FORM AT 1.45 A
分子名称: CYTOCHROME C', HEME C
著者Antonyuk, S.V, Eady, R.R, Hasnain, S.S.
登録日2011-06-02
公開日2012-04-18
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (1.45 Å)
主引用文献Carbon Monoxide Poisoning is Prevented by the Energy Costs of Conformational Changes in Gas- Binding Haemproteins.
Proc.Natl.Acad.Sci.USA, 108, 2011
2YL1
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CYTOCHROME C PRIME FROM ALCALIGENES XYLOSOXIDANS: CARBON MONOOXIDE BOUND L16A VARIANT AT 1.03 A RESOLUTION - Restraint refinement
分子名称: CARBON MONOXIDE, CYTOCHROME C', HEME C
著者Antonyuk, S.V, Eady, R.R, Hasnain, S.S.
登録日2011-05-30
公開日2011-10-05
最終更新日2024-10-09
実験手法X-RAY DIFFRACTION (1.03 Å)
主引用文献Carbon Monoxide Poisoning is Prevented by the Energy Costs of Conformational Changes in Gas- Binding Haemproteins.
Proc.Natl.Acad.Sci.USA, 108, 2011
2YV3
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Crystal Structure of Aspartate Semialdehyde Dehydrogenase from Thermus thermophilus HB8
分子名称: Aspartate-semialdehyde dehydrogenase
著者Kagawa, W, Fujikawa, N, Kurumizaka, H, Bessho, Y, Ellis, M.J, Antonyuk, S.V, Strange, R.W, Hasnain, S.S, Kuramitsu, S, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
登録日2007-04-07
公開日2007-10-09
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Crystal Structure of Aspartate Semialdehyde Dehydrogenase from Thermus thermophilus HB8
To be Published
2XWZ
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STRUCTURE OF THE RECOMBINANT NATIVE NITRITE REDUCTASE FROM ALCALIGENES XYLOSOXIDANS complexed with nitrite
分子名称: ACETATE ION, COPPER (II) ION, DISSIMILATORY COPPER-CONTAINING NITRITE REDUCTASE, ...
著者Antonyuk, S.V, Leferink, N.G.H, Han, C, Heyes, D.J, Rigby, S.E.J, Hough, M.A, Eady, R.R, Scrutton, N.S, Hasnain, S.S.
登録日2010-11-06
公開日2011-05-18
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.34 Å)
主引用文献Proton-Coupled Electron Transfer in the Catalytic Cycle of Alcaligenes Xylosoxidans Copper-Dependent Nitrite Reductase.
Biochemistry, 50, 2011
2WZ5
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L38V SOD1 mutant complexed with L-methionine.
分子名称: COPPER (II) ION, METHIONINE, SULFATE ION, ...
著者Antonyuk, S.V, Strange, R.W, Hasnain, S.S.
登録日2009-11-23
公開日2010-12-08
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Structural Discovery of Small Molecule Binding Sites in Cu-Zn Human Superoxide Dismutase Familial Amyotrophic Lateral Sclerosis Mutants Provides Insights for Lead Optimization.
J.Med.Chem., 53, 2010
2WYZ
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L38V SOD1 mutant complexed with UMP
分子名称: COPPER (II) ION, SULFATE ION, SUPEROXIDE DISMUTASE [CU-ZN], ...
著者Antonyuk, S.V, Strange, R.W, Hasnain, S.S.
登録日2009-11-20
公開日2010-10-27
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Structural Discovery of Small Molecule Binding Sites in Cu-Zn Human Superoxide Dismutase Familial Amyotrophic Lateral Sclerosis Mutants Provides Insights for Lead Optimization.
J.Med.Chem., 53, 2010
2XLV
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BU of 2xlv by Molmil
Cytochrome c prime from Alcaligenes xylosoxidans: Ferrous R124F variant with bound NO
分子名称: CYTOCHROME C', HEME C, NITRIC OXIDE
著者Hough, M.A, Antonyuk, S.V, Strange, R, Hasnain, S.S.
登録日2010-07-22
公開日2010-11-10
最終更新日2024-10-09
実験手法X-RAY DIFFRACTION (1.24 Å)
主引用文献Distal-to-Proximal No Conversion in Hemoproteins: The Role of the Proximal Pocket.
J.Mol.Biol., 405, 2011
2XLE
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BU of 2xle by Molmil
Cytochrome c prime from Alcaligenes xylosoxidans: Ferrous R124K variant with bound NO
分子名称: CYTOCHROME C', HEME C, NITRIC OXIDE, ...
著者Hough, M.A, Antonyuk, S.V, Hasnain, S.S.
登録日2010-07-20
公開日2010-11-10
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (1.12 Å)
主引用文献Distal-to-Proximal No Conversion in Hemoproteins: The Role of the Proximal Pocket.
J.Mol.Biol., 405, 2011
2XL6
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Cytochrome c prime from Alcaligenes xylosoxidans: Ferrous R124A variant with bound NO
分子名称: CYTOCHROME C', HEME C, NITRATE ION, ...
著者Hough, M.A, Antonyuk, S.V, Hasnain, S.S.
登録日2010-07-19
公開日2010-11-10
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (1.07 Å)
主引用文献Distal-to-Proximal No Conversion in Hemoproteins: The Role of the Proximal Pocket.
J.Mol.Biol., 405, 2011
2XLD
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Cytochrome c prime from Alcaligenes xylosoxidans: Ferrous R124Q variant
分子名称: CYTOCHROME C', HEME C, SULFATE ION
著者Hough, M.A, Antonyuk, S.V, Hasnain, S.S.
登録日2010-07-20
公開日2010-11-10
最終更新日2024-10-09
実験手法X-RAY DIFFRACTION (1.4 Å)
主引用文献Distal-to-Proximal No Conversion in Hemoproteins: The Role of the Proximal Pocket.
J.Mol.Biol., 405, 2011
2XX1
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STRUCTURE OF THE N90S MUTANT OF NITRITE REDUCTASE FROM ALCALIGENES XYLOSOXIDANS complexed with nitrite
分子名称: COPPER (II) ION, DISSIMILATORY COPPER-CONTAINING NITRITE REDUCTASE, NITRITE ION, ...
著者Antonyuk, S.V, Leferink, N.G.H, Han, C, Heyes, D.J, Rigby, S.E.J, Hough, M.A, Eady, R.R, Scrutton, N.S, Hasnain, S.S.
登録日2010-11-07
公開日2011-05-18
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Proton-Coupled Electron Transfer in the Catalytic Cycle of Alcaligenes Xylosoxidans Copper-Dependent Nitrite Reductase.
Biochemistry, 50, 2011
2XL8
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REDUCED STRUCTURE OF R124F MUTANT OF CYTOCHROME C' FROM ALCALIGENES XYLOSOXIDANS
分子名称: CYTOCHROME C', HEME C, SULFATE ION
著者Hough, M.A, Antonyuk, S.V, Barbieri, S, Rustage, N, McKay, A.L, Servid, A.E, Eady, R.R, Andrew, C.R, Hasnain, S.S.
登録日2010-07-20
公開日2010-09-29
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (1.14 Å)
主引用文献Distal-to-Proximal No Conversion in Hemoproteins: The Role of the Proximal Pocket.
J.Mol.Biol., 405, 2011
2XM0
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Cytochrome c prime from Alcaligenes xylosoxidans: Ferrous R124K variant
分子名称: CYTOCHROME C', HEME C
著者Hough, M.A, Antonyuk, S.V, Hasnain, S.S.
登録日2010-07-22
公開日2010-11-10
最終更新日2020-03-11
実験手法X-RAY DIFFRACTION (1.25 Å)
主引用文献Distal-to-Proximal No Conversion in Hemoproteins: The Role of the Proximal Pocket.
J.Mol.Biol., 405, 2011
2WZ6
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G93A SOD1 mutant complexed with Quinazoline.
分子名称: 4-(4-METHYL-1,4-DIAZEPAN-1-YL)-2-(TRIFLUOROMETHYL)QUINAZOLINE, COPPER (II) ION, SULFATE ION, ...
著者Antonyuk, S.V, Strange, R.W, Hasnain, S.S.
登録日2009-11-23
公開日2010-12-08
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (1.55 Å)
主引用文献Structural Discovery of Small Molecule Binding Sites in Cu-Zn Human Superoxide Dismutase Familial Amyotrophic Lateral Sclerosis Mutants Provides Insights for Lead Optimization.
J.Med.Chem., 53, 2010
2WZ0
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L38V SOD1 mutant complexed with aniline.
分子名称: 2-METHOXY-5-METHYLANILINE, COPPER (II) ION, D-SERINE, ...
著者Antonyuk, S, Strange, R.W, Hasnain, S.S.
登録日2009-11-20
公開日2010-12-08
最終更新日2024-10-09
実験手法X-RAY DIFFRACTION (1.72 Å)
主引用文献Structural Discovery of Small Molecule Binding Sites in Cu-Zn Human Superoxide Dismutase Familial Amyotrophic Lateral Sclerosis Mutants Provides Insights for Lead Optimization.
J.Med.Chem., 53, 2010

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