2WZ5

L38V SOD1 mutant complexed with L-methionine.

Summary for 2WZ5

Entry DOI	10.2210/pdb2wz5/pdb
Related	1AZV 1BA9 1DSW 1FUN 1HL4 1HL5 1KMG 1L3N 1MFM 1N18 1N19 1OEZ 1OZT 1OZU 1P1V 1PTZ 1PU0 1RK7 1SOS 1SPD 1UXL 1UXM 2AF2 2C9S 2C9U 2C9V 2V0A 2VR6 2VR7 2VR8 2WKO 2WYT 2WYZ 2WZ0 2WZ6 4SOD
Descriptor	SUPEROXIDE DISMUTASE [CU-ZN], ZINC ION, COPPER (II) ION, ... (6 entities in total)
Functional Keywords	oxidoreductase, disease mutation, neurodegeneration, amyotrophic lateral sclerosis, metal-binding, antioxidant
Biological source	HOMO SAPIENS (HUMAN)
Cellular location	Cytoplasm : P00441
Total number of polymer chains	2
Total formula weight	32537.00
Authors	Antonyuk, S.V.,Strange, R.W.,Hasnain, S.S. (deposition date: 2009-11-23, release date: 2010-12-08, Last modification date: 2023-12-20)
Primary citation	Antonyuk, S.,Strange, R.W.,Hasnain, S.S. Structural Discovery of Small Molecule Binding Sites in Cu-Zn Human Superoxide Dismutase Familial Amyotrophic Lateral Sclerosis Mutants Provides Insights for Lead Optimization. J.Med.Chem., 53:1402-, 2010 Cited by PubMed: 20067275 DOI: 10.1021/JM9017948 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.5 Å)

Structure validation