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PDB: 174 results

6R12
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BU of 6r12 by Molmil
Cereblon isoform 4 from Magnetospirillum gryphiswaldense in complex with compound 7b
Descriptor: CHLORIDE ION, Cereblon isoform 4, PHOSPHATE ION, ...
Authors:Heim, C, Hartmann, M.D.
Deposit date:2019-03-13
Release date:2019-08-07
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.74 Å)
Cite:De-Novo Design of Cereblon (CRBN) Effectors Guided by Natural Hydrolysis Products of Thalidomide Derivatives.
J.Med.Chem., 62, 2019
6R18
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BU of 6r18 by Molmil
Cereblon isoform 4 from Magnetospirillum gryphiswaldense in complex with compound 11a
Descriptor: CHLORIDE ION, Cereblon isoform 4, PHOSPHATE ION, ...
Authors:Heim, C, Hartmann, M.D.
Deposit date:2019-03-14
Release date:2019-08-07
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.35 Å)
Cite:De-Novo Design of Cereblon (CRBN) Effectors Guided by Natural Hydrolysis Products of Thalidomide Derivatives.
J.Med.Chem., 62, 2019
6R19
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BU of 6r19 by Molmil
Cereblon isoform 4 from Magnetospirillum gryphiswaldense in complex with compound 20a
Descriptor: Cereblon isoform 4, PHOSPHATE ION, S-Thalidomide, ...
Authors:Heim, C, Hartmann, M.D.
Deposit date:2019-03-14
Release date:2019-08-07
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.45 Å)
Cite:De-Novo Design of Cereblon (CRBN) Effectors Guided by Natural Hydrolysis Products of Thalidomide Derivatives.
J.Med.Chem., 62, 2019
6R1A
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BU of 6r1a by Molmil
Cereblon isoform 4 from Magnetospirillum gryphiswaldense in complex with compound 20b
Descriptor: Cereblon isoform 4, PHOSPHATE ION, S-Thalidomide, ...
Authors:Heim, C, Hartmann, M.D.
Deposit date:2019-03-14
Release date:2019-08-07
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.54 Å)
Cite:De-Novo Design of Cereblon (CRBN) Effectors Guided by Natural Hydrolysis Products of Thalidomide Derivatives.
J.Med.Chem., 62, 2019
6R1D
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BU of 6r1d by Molmil
Cereblon isoform 4 from Magnetospirillum gryphiswaldense in complex with compound 7d, co-crystallized
Descriptor: (phenylmethyl) ~{N}-[(3~{S})-2,5-bis(oxidanylidene)pyrrolidin-3-yl]carbamate, Cereblon isoform 4, ZINC ION
Authors:Heim, C, Hartmann, M.D.
Deposit date:2019-03-14
Release date:2019-08-07
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.1 Å)
Cite:De-Novo Design of Cereblon (CRBN) Effectors Guided by Natural Hydrolysis Products of Thalidomide Derivatives.
J.Med.Chem., 62, 2019
6R1K
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BU of 6r1k by Molmil
Cereblon isoform 4 from Magnetospirillum gryphiswaldense in complex with compound 7c
Descriptor: Cereblon isoform 4, PHOSPHATE ION, ZINC ION, ...
Authors:Heim, C, Hartmann, M.D.
Deposit date:2019-03-14
Release date:2019-08-07
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.94 Å)
Cite:De-Novo Design of Cereblon (CRBN) Effectors Guided by Natural Hydrolysis Products of Thalidomide Derivatives.
J.Med.Chem., 62, 2019
6R1W
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BU of 6r1w by Molmil
Cereblon isoform 4 from Magnetospirillum gryphiswaldense in complex with compound 16b
Descriptor: (4-azanylcyclohexyl)methyl ~{N}-[(3~{S})-2,6-bis(oxidanylidene)piperidin-3-yl]carbamate, Cereblon isoform 4, PHOSPHATE ION, ...
Authors:Heim, C, Hartmann, M.D.
Deposit date:2019-03-15
Release date:2019-08-07
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.35 Å)
Cite:De-Novo Design of Cereblon (CRBN) Effectors Guided by Natural Hydrolysis Products of Thalidomide Derivatives.
J.Med.Chem., 62, 2019
6R1X
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BU of 6r1x by Molmil
Cereblon isoform 4 from Magnetospirillum gryphiswaldense in complex with compound 7a
Descriptor: Cereblon isoform 4, ZINC ION, ~{N}-[(3~{S})-2,5-bis(oxidanylidene)pyrrolidin-3-yl]-3-methyl-but-2-enamide
Authors:Heim, C, Hartmann, M.D.
Deposit date:2019-03-15
Release date:2019-08-07
Last modified:2024-05-15
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:De-Novo Design of Cereblon (CRBN) Effectors Guided by Natural Hydrolysis Products of Thalidomide Derivatives.
J.Med.Chem., 62, 2019
6R1C
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BU of 6r1c by Molmil
Cereblon isoform 4 from Magnetospirillum gryphiswaldense in complex with compound 12a
Descriptor: 4-[[4-[[(3~{S})-2,5-bis(oxidanylidene)pyrrolidin-3-yl]carbamoyloxymethyl]phenyl]methylamino]-4-oxidanylidene-butanoic acid, ASPARTIC ACID, CHLORIDE ION, ...
Authors:Heim, C, Hartmann, M.D.
Deposit date:2019-03-14
Release date:2019-08-07
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:De-Novo Design of Cereblon (CRBN) Effectors Guided by Natural Hydrolysis Products of Thalidomide Derivatives.
J.Med.Chem., 62, 2019
2WFW
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BU of 2wfw by Molmil
Structure and activity of the N-terminal substrate recognition domains in proteasomal ATPases - The Arc domain structure
Descriptor: ARC
Authors:Djuranovic, S, Hartmann, M.D, Habeck, M, Ursinus, A, Zwickl, P, Martin, J, Lupas, A.N, Zeth, K.
Deposit date:2009-04-15
Release date:2009-05-12
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Structure and Activity of the N-Terminal Substrate Recognition Domains in Proteasomal Atpases.
Mol.Cell, 34, 2009
2VC8
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BU of 2vc8 by Molmil
Crystal structure of the LSm domain of human EDC3 (enhancer of decapping 3)
Descriptor: ENHANCER OF MRNA-DECAPPING PROTEIN 3
Authors:Tritschler, F, Hartmann, M.D, Weichenrieder, O.
Deposit date:2007-09-19
Release date:2007-10-16
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (1.31 Å)
Cite:A Divergent Sm Fold in Edc3 Proteins Mediates Dcp1 Binding and P-Body Targeting.
Mol.Cell.Biol., 27, 2007
5A1Q
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BU of 5a1q by Molmil
Crystal structure of Archaeoglobus fulgidus Af1502
Descriptor: AF1502, SULFATE ION
Authors:Albrecht, R, Lupas, A.N, Hartmann, M.D.
Deposit date:2015-05-04
Release date:2015-10-07
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Stac-A New Domain Associated with Transmembrane Solute Transport and Two-Component Signal Transduction Systems.
J.Mol.Biol., 427, 2015
2XR1
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BU of 2xr1 by Molmil
DIMERIC ARCHAEAL CLEAVAGE AND POLYADENYLATION SPECIFICITY FACTOR WITH N-TERMINAL KH DOMAINS (KH-CPSF) FROM METHANOSARCINA MAZEI
Descriptor: CLEAVAGE AND POLYADENYLATION SPECIFICITY FACTOR 100 KD SUBUNIT, ZINC ION
Authors:Mir-Montazeri, B, Ammelburg, M, Forouzan, D, Lupas, A.N, Hartmann, M.D.
Deposit date:2010-09-08
Release date:2010-10-06
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.59 Å)
Cite:Crystal Structure of a Dimeric Archaeal Cleavage and Polyadenylation Specificity Factor.
J.Struct.Biol., 173, 2011
2WPY
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BU of 2wpy by Molmil
GCN4 leucine zipper mutant with one VxxNxxx motif coordinating chloride
Descriptor: CHLORIDE ION, GENERAL CONTROL PROTEIN GCN4
Authors:Zeth, K, Hartmann, M.D, Albrecht, R, Lupas, A.N, Hernandez Alvarez, B.
Deposit date:2009-08-12
Release date:2009-11-03
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:A Coiled-Coil Motif that Sequesters Ions to the Hydrophobic Core.
Proc.Natl.Acad.Sci.USA, 106, 2009
2WPZ
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BU of 2wpz by Molmil
GCN4 leucine zipper mutant with two VxxNxxx motifs coordinating chloride
Descriptor: CHLORIDE ION, GENERAL CONTROL PROTEIN GCN4
Authors:Zeth, K, Hartmann, M.D, Albrecht, R, Lupas, A.N, Hernandez Alvarez, B.
Deposit date:2009-08-12
Release date:2009-11-03
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (1.25 Å)
Cite:A Coiled-Coil Motif that Sequesters Ions to the Hydrophobic Core.
Proc.Natl.Acad.Sci.USA, 106, 2009
6FYH
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BU of 6fyh by Molmil
Disulfide between ubiquitin G76C and the E3 HECT ligase Huwe1
Descriptor: E3 ubiquitin-protein ligase HUWE1, Polyubiquitin-B, SULFATE ION, ...
Authors:Jaeckl, M, Hartmann, M.D, Wiesner, S.
Deposit date:2018-03-12
Release date:2018-07-11
Last modified:2024-10-16
Method:X-RAY DIFFRACTION (2.906 Å)
Cite:beta-Sheet Augmentation Is a Conserved Mechanism of Priming HECT E3 Ligases for Ubiquitin Ligation.
J. Mol. Biol., 430, 2018
7O92
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BU of 7o92 by Molmil
hypothetical protein UY81_C0065G0003 residues 18-54 from Candidatus Giovannonibacteria bacterium fused to GCN4 adaptors
Descriptor: hypothetical protein UY81_C0065G0003 residues 18-54 from Candidatus Giovannonibacteria bacterium fused to GCN4 adaptors
Authors:Adlakha, J, Albrecht, R, Hartmann, M.D.
Deposit date:2021-04-15
Release date:2022-05-04
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:hypothetical protein UY81_C0065G0003 residues 18-54 from Candidatus Giovannonibacteria bacterium fused to GCN4 adaptors
To Be Published
7OAF
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BU of 7oaf by Molmil
conserved hypothetical protein residues 311-335 from Candidatus Magnetomorum sp. HK-1 fused to GCN4 adaptors, mutant beta1/A, crystal form III
Descriptor: General control transcription factor GCN4,conserved hypothetical protein residues 311-335 from Candidatus Magnetomorum sp. HK-1 fused to GCN4 adaptors, mutant beta1/A,General control transcription factor GCN4, PENTAETHYLENE GLYCOL
Authors:Adlakha, J, Albrecht, R, Hartmann, M.D.
Deposit date:2021-04-19
Release date:2022-05-04
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (1.45 Å)
Cite:conserved hypothetical protein residues 311-335 from Candidatus Magnetomorum sp. HK-1 fused to GCN4 adaptors, mutant beta1/A, crystal form III
To Be Published
7OAC
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BU of 7oac by Molmil
conserved hypothetical protein residues 311-335 from Candidatus Magnetomorum sp. HK-1 fused to GCN4 adaptors, mutant beta1/A, crystal form I
Descriptor: General control transcription factor GCN4,conserved hypothetical protein residues 311-335 from Candidatus Magnetomorum sp. HK-1 fused to GCN4 adaptors, mutant beta1/A,General control transcription factor GCN4
Authors:Adlakha, J, Albrecht, R, Hartmann, M.D.
Deposit date:2021-04-19
Release date:2022-05-04
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:conserved hypothetical protein residues 311-335 from Candidatus Magnetomorum sp. HK-1 fused to GCN4 adaptors, mutant beta1/A, crystal form I
To Be Published
7O9V
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BU of 7o9v by Molmil
hypothetical protein OMM_04225 residues 244-274 from Candidatus Magnetoglobus multicellularis fused to GCN4 adaptors
Descriptor: General control transcription factor GCN4,hypothetical protein OMM_04225 residues 244-274 from Candidatus Magnetoglobus multicellularis fused to GCN4 adaptors,General control transcription factor GCN4
Authors:Adlakha, J, Albrecht, R, Hartmann, M.D.
Deposit date:2021-04-17
Release date:2022-05-04
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (1.99 Å)
Cite:hypothetical protein OMM_04225 residues 244-274 from Candidatus Magnetoglobus multicellularis fused to GCN4 adaptors
To Be Published
7OAH
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BU of 7oah by Molmil
conserved hypothetical protein residues 311-335 from Candidatus Magnetomorum sp. HK-1 fused to GCN4 adaptors, mutant beta2/A
Descriptor: General control transcription factor GCN4,conserved hypothetical protein residues 311-335 from Candidatus Magnetomorum sp. HK-1 fused to GCN4 adaptors, mutant beta2/A,General control transcription factor GCN4, TETRAETHYLENE GLYCOL
Authors:Adlakha, J, Albrecht, R, Hartmann, M.D.
Deposit date:2021-04-19
Release date:2022-05-04
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (1.694 Å)
Cite:conserved hypothetical protein residues 311-335 from Candidatus Magnetomorum sp. HK-1 fused to GCN4 adaptors, mutant beta2/A
To Be Published
7OAA
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BU of 7oaa by Molmil
conserved hypothetical protein residues 311-335 from Candidatus Magnetomorum sp. HK-1 fused to GCN4 adaptors
Descriptor: General control transcription factor GCN4,conserved hypothetical protein residues 311-335 from Candidatus Magnetomorum sp. HK-1 fused to GCN4 adaptors,General control transcription factor GCN4
Authors:Adlakha, J, Albrecht, R, Hartmann, M.D.
Deposit date:2021-04-19
Release date:2022-05-04
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:conserved hypothetical protein residues 311-335 from Candidatus Magnetomorum sp. HK-1 fused to GCN4 adaptors
To Be Published
7O97
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BU of 7o97 by Molmil
hypothetical protein UY81_C0065G0003 from Candidatus Giovannonibacteria bacterium converted into a canonical coiled coil
Descriptor: hypothetical protein UY81_C0065G0003 from Candidatus Giovannonibacteria bacterium converted into a canonical coiled coil
Authors:Adlakha, J, Albrecht, R, Hartmann, M.D.
Deposit date:2021-04-15
Release date:2022-05-04
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (2 Å)
Cite:hypothetical protein UY81_C0065G0003 from Candidatus Giovannonibacteria bacterium converted into a canonical coiled coil
To Be Published
7OAD
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BU of 7oad by Molmil
conserved hypothetical protein residues 311-335 from Candidatus Magnetomorum sp. HK-1 fused to GCN4 adaptors, mutant beta1/A, crystal form II
Descriptor: General control transcription factor GCN4,conserved hypothetical protein residues 311-335 from Candidatus Magnetomorum sp. HK-1 fused to GCN4 adaptors, mutant beta1/A,General control transcription factor GCN4
Authors:Adlakha, J, Albrecht, R, Hartmann, M.D.
Deposit date:2021-04-19
Release date:2022-05-04
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (2 Å)
Cite:conserved hypothetical protein residues 311-335 from Candidatus Magnetomorum sp. HK-1 fused to GCN4 adaptors, mutant beta1/A, crystal form II
To Be Published

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