8UK3
 
 | | The rotavirus VP5*/VP8* conformational transition permeabilizes membranes to Ca2+ (class 6 reconstruction) | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, Outer capsid glycoprotein VP7, ... | | Authors: | De Sautu, M, Herrmann, T, Jenni, S, Harrison, S.C. | | Deposit date: | 2023-10-12 | | Release date: | 2024-03-27 | | Last modified: | 2024-04-17 | | Method: | ELECTRON MICROSCOPY (8 Å) | | Cite: | The rotavirus VP5*/VP8* conformational transition permeabilizes membranes to Ca2.
Plos Pathog., 20, 2024
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8UK2
 | | The rotavirus VP5*/VP8* conformational transition permeabilizes membranes to Ca2+ (class 5 reconstruction) | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, Outer capsid glycoprotein VP7, ... | | Authors: | De Sautu, M, Herrmann, T, Jenni, S, Harrison, S.C. | | Deposit date: | 2023-10-12 | | Release date: | 2024-03-27 | | Last modified: | 2024-04-17 | | Method: | ELECTRON MICROSCOPY (8 Å) | | Cite: | The rotavirus VP5*/VP8* conformational transition permeabilizes membranes to Ca2.
Plos Pathog., 20, 2024
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7UI0
 | | Post-fusion ectodomain of HSV-1 gB in complex with HSV010-13 Fab | | Descriptor: | Envelope glycoprotein B, HSV10-13 Fab Heavy chain, HSV10-13 Light chain | | Authors: | Windsor, I.W, Kong, S.L, Garforth, S.J, Almo, S.C, Harrison, S.C. | | Deposit date: | 2022-03-28 | | Release date: | 2023-02-08 | | Last modified: | 2023-02-15 | | Method: | ELECTRON MICROSCOPY (3.4 Å) | | Cite: | A non-neutralizing glycoprotein B monoclonal antibody protects against herpes simplex virus disease in mice.
J.Clin.Invest., 133, 2023
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7UHZ
 | | Post-fusion ectodomain of HSV-1 gB in complex with BMPC-23 Fab | | Descriptor: | BMPC-23 Fab Heavy chain, BMPC-23 Fab Light chain, Envelope glycoprotein B | | Authors: | Windsor, I.W, Kong, S.L, Garforth, S.J, Almo, S.C, Harrison, S.C. | | Deposit date: | 2022-03-28 | | Release date: | 2023-02-08 | | Last modified: | 2023-02-15 | | Method: | ELECTRON MICROSCOPY (3.3 Å) | | Cite: | A non-neutralizing glycoprotein B monoclonal antibody protects against herpes simplex virus disease in mice.
J.Clin.Invest., 133, 2023
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8SMV
 | | GPR161 Gs heterotrimer | | Descriptor: | CHOLESTEROL, G-protein coupled receptor 161, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... | | Authors: | Hoppe, N, Manglik, A, Harrison, S. | | Deposit date: | 2023-04-26 | | Release date: | 2024-02-21 | | Last modified: | 2024-03-20 | | Method: | ELECTRON MICROSCOPY (2.74 Å) | | Cite: | GPR161 structure uncovers the redundant role of sterol-regulated ciliary cAMP signaling in the Hedgehog pathway.
Biorxiv, 2023
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5W6G
 | | Human antibody 6649 in complex with influenza hemagglutinin H1 Solomon Islands | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 6649 antibody heavy chain, ... | | Authors: | Raymond, D.D, Harrison, S.C. | | Deposit date: | 2017-06-16 | | Release date: | 2017-12-20 | | Last modified: | 2023-10-04 | | Method: | X-RAY DIFFRACTION (2.79 Å) | | Cite: | Conserved epitope on influenza-virus hemagglutinin head defined by a vaccine-induced antibody.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
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8V11
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5W94
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5IBU
 | | 6652 Fab (unbound) | | Descriptor: | 6652 Heavy Chain, 6652 Light Chain | | Authors: | Raymond, D.D, Harrison, S.C. | | Deposit date: | 2016-02-22 | | Release date: | 2016-11-09 | | Last modified: | 2023-09-27 | | Method: | X-RAY DIFFRACTION (1.71 Å) | | Cite: | Influenza immunization elicits antibodies specific for an egg-adapted vaccine strain.
Nat. Med., 22, 2016
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5IBL
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4XI2
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4XDN
 | | Crystal structure of Scc4 in complex with Scc2n | | Descriptor: | MAU2 chromatid cohesion factor homolog, SULFATE ION, Sister chromatid cohesion protein 2 | | Authors: | Hinshaw, S.M, Harrison, S.C. | | Deposit date: | 2014-12-19 | | Release date: | 2015-06-17 | | Last modified: | 2024-02-28 | | Method: | X-RAY DIFFRACTION (2.08 Å) | | Cite: | Structural evidence for Scc4-dependent localization of cohesin loading.
Elife, 4, 2015
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5IBT
 | | UCA Fab (unbound) from 6515 Lineage | | Descriptor: | GLYCEROL, UCA Heavy Chain, UCA Light Chain | | Authors: | Raymond, D.D, Harrison, S.C. | | Deposit date: | 2016-02-22 | | Release date: | 2016-11-09 | | Last modified: | 2023-09-27 | | Method: | X-RAY DIFFRACTION (2.4 Å) | | Cite: | Influenza immunization elicits antibodies specific for an egg-adapted vaccine strain.
Nat. Med., 22, 2016
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5W6C
 | | UCA Fab (unbound) from 6649 Lineage | | Descriptor: | UCA Fab heavy chain, UCA Fab light chain | | Authors: | Raymond, D.D, Harrison, S.C. | | Deposit date: | 2017-06-16 | | Release date: | 2017-12-13 | | Last modified: | 2023-10-04 | | Method: | X-RAY DIFFRACTION (1.634 Å) | | Cite: | Conserved epitope on influenza-virus hemagglutinin head defined by a vaccine-induced antibody.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
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3CRO
 | | THE PHAGE 434 CRO/OR1 COMPLEX AT 2.5 ANGSTROMS RESOLUTION | | Descriptor: | DNA (5'-D(*AP*AP*GP*TP*AP*CP*AP*AP*AP*CP*TP*TP*TP*CP*TP*TP*G P*TP*AP*T)-3'), DNA (5'-D(*TP*AP*TP*AP*CP*AP*AP*GP*AP*AP*AP*GP*TP*TP*TP*GP*T P*AP*CP*T)-3'), PROTEIN (434 CRO) | | Authors: | Mondragon, A, Harrison, S.C. | | Deposit date: | 1990-07-06 | | Release date: | 1991-10-15 | | Last modified: | 2024-02-21 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | The phage 434 Cro/OR1 complex at 2.5 A resolution.
J.Mol.Biol., 219, 1991
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8V10
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4YJZ
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5W08
 | | A/Texas/50/2012(H3N2) Influenza hemagglutinin in complex with K03.12 Fab | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, GLYCEROL, ... | | Authors: | McCarthy, K.R, Harrison, S.C. | | Deposit date: | 2017-05-30 | | Release date: | 2018-02-14 | | Last modified: | 2023-10-04 | | Method: | X-RAY DIFFRACTION (2.6 Å) | | Cite: | Memory B Cells that Cross-React with Group 1 and Group 2 Influenza A Viruses Are Abundant in Adult Human Repertoires.
Immunity, 48, 2018
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5W0D
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4QHK
 | | UCA (unbound) from CH103 Lineage | | Descriptor: | UCA heavy chain, UCA light chain | | Authors: | Fera, D, Harrison, S.C. | | Deposit date: | 2014-05-28 | | Release date: | 2014-06-11 | | Last modified: | 2023-09-20 | | Method: | X-RAY DIFFRACTION (3.487 Å) | | Cite: | Affinity maturation in an HIV broadly neutralizing B-cell lineage through reorientation of variable domains.
Proc.Natl.Acad.Sci.USA, 111, 2014
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4QHN
 | | I2 (unbound) from CH103 Lineage | | Descriptor: | I2 heavy chain, I2 light chain | | Authors: | Fera, D, Harrison, S.C. | | Deposit date: | 2014-05-28 | | Release date: | 2014-06-11 | | Last modified: | 2023-09-20 | | Method: | X-RAY DIFFRACTION (3 Å) | | Cite: | Affinity maturation in an HIV broadly neutralizing B-cell lineage through reorientation of variable domains.
Proc.Natl.Acad.Sci.USA, 111, 2014
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4QHM
 | | I3.1 (unbound) from CH103 Lineage | | Descriptor: | I2 light chain, I3 heavy chain | | Authors: | Fera, D, Harrison, S.C. | | Deposit date: | 2014-05-28 | | Release date: | 2014-06-11 | | Last modified: | 2023-09-20 | | Method: | X-RAY DIFFRACTION (3.23 Å) | | Cite: | Affinity maturation in an HIV broadly neutralizing B-cell lineage through reorientation of variable domains.
Proc.Natl.Acad.Sci.USA, 111, 2014
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4QHL
 | | I3.2 (unbound) from CH103 Lineage | | Descriptor: | I3 heavy chain, UCA light chain | | Authors: | Fera, D, Harrison, S.C. | | Deposit date: | 2014-05-28 | | Release date: | 2014-06-11 | | Last modified: | 2023-09-20 | | Method: | X-RAY DIFFRACTION (3.153 Å) | | Cite: | Affinity maturation in an HIV broadly neutralizing B-cell lineage through reorientation of variable domains.
Proc.Natl.Acad.Sci.USA, 111, 2014
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5A22
 | | Structure of the L protein of vesicular stomatitis virus from electron cryomicroscopy | | Descriptor: | VESICULAR STOMATITIS VIRUS L POLYMERASE, ZINC ION | | Authors: | Liang, B, Li, Z, Jenni, S, Rameh, A.A, Morin, B.M, Grant, T, Grigorieff, N, Harrison, S.C, Whelan, S.P.J. | | Deposit date: | 2015-05-06 | | Release date: | 2015-08-19 | | Last modified: | 2019-04-24 | | Method: | ELECTRON MICROSCOPY (3.8 Å) | | Cite: | Structure of the L Protein of Vesicular Stomatitis Virus from Electron Cryomicroscopy.
Cell(Cambridge,Mass.), 162, 2015
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6E8W
 | | MPER-TM Domain of HIV-1 envelope glycoprotein (Env) | | Descriptor: | Envelope glycoprotein gp160 | | Authors: | Fu, Q, Shaik, M.M, Cai, Y, Ghantous, F, Piai, A, Peng, H, Rits-Volloch, S, Liu, Z, Harrison, S.C, Seaman, M.S, Chen, B, Chou, J.J. | | Deposit date: | 2018-07-31 | | Release date: | 2018-09-05 | | Last modified: | 2024-05-15 | | Method: | SOLUTION NMR | | Cite: | Structure of the membrane proximal external region of HIV-1 envelope glycoprotein.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
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