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7UI0

Post-fusion ectodomain of HSV-1 gB in complex with HSV010-13 Fab

This is a non-PDB format compatible entry.
Summary for 7UI0
Entry DOI10.2210/pdb7ui0/pdb
EMDB information26521
DescriptorEnvelope glycoprotein B, HSV10-13 Fab Heavy chain, HSV10-13 Light chain (3 entities in total)
Functional Keywordsglycoprotein, fusogen, antibody, adcc, viral protein, viral protein-immune system complex, viral protein/immune system
Biological sourceHuman alphaherpesvirus 1 strain KOS
More
Total number of polymer chains9
Total formula weight289793.96
Authors
Windsor, I.W.,Kong, S.L.,Garforth, S.J.,Almo, S.C.,Harrison, S.C. (deposition date: 2022-03-28, release date: 2023-02-08, Last modification date: 2023-02-15)
Primary citationKuraoka, M.,Aschner, C.B.,Windsor, I.W.,Mahant, A.M.,Garforth, S.J.,Kong, S.L.,Achkar, J.M.,Almo, S.C.,Kelsoe, G.,Herold, B.C.
A non-neutralizing glycoprotein B monoclonal antibody protects against herpes simplex virus disease in mice.
J.Clin.Invest., 133:-, 2023
Cited by
PubMed: 36454639
DOI: 10.1172/JCI161968
PDB entries with the same primary citation
Experimental method
ELECTRON MICROSCOPY (3.4 Å)
Structure validation

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