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7UHZ

Post-fusion ectodomain of HSV-1 gB in complex with BMPC-23 Fab

This is a non-PDB format compatible entry.
Summary for 7UHZ
Entry DOI10.2210/pdb7uhz/pdb
EMDB information26520
DescriptorBMPC-23 Fab Heavy chain, BMPC-23 Fab Light chain, Envelope glycoprotein B (3 entities in total)
Functional Keywordsglycoprotein, fusogen, antibody, adcc, viral protein
Biological sourceMus musculus
More
Total number of polymer chains9
Total formula weight291499.44
Authors
Windsor, I.W.,Kong, S.L.,Garforth, S.J.,Almo, S.C.,Harrison, S.C. (deposition date: 2022-03-28, release date: 2023-02-08, Last modification date: 2023-02-15)
Primary citationKuraoka, M.,Aschner, C.B.,Windsor, I.W.,Mahant, A.M.,Garforth, S.J.,Kong, S.L.,Achkar, J.M.,Almo, S.C.,Kelsoe, G.,Herold, B.C.
A non-neutralizing glycoprotein B monoclonal antibody protects against herpes simplex virus disease in mice.
J.Clin.Invest., 133:-, 2023
Cited by
PubMed: 36454639
DOI: 10.1172/JCI161968
PDB entries with the same primary citation
Experimental method
ELECTRON MICROSCOPY (3.3 Å)
Structure validation

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