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PDB: 18 件
2IQD
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Crystal Structure of Aldose Reductase complexed with Lipoic Acid
分子名称: Aldose reductase, LIPOIC ACID, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
著者Harrison, D.H.T, Carlson, E, Pape, E, Brownlee, J.M.
登録日2006-10-13
公開日2006-11-28
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structural and thermodynamic studies of simple aldose reductase-inhibitor complexes.
Bioorg.Chem., 34, 2006
2INZ
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Crystal Structure of Aldose Reductase complexed with 2-Hydroxyphenylacetic Acid
分子名称: (2-HYDROXYPHENYL)ACETIC ACID, Aldose reductase, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
著者Harrison, D.H.T, Pape, E, Carlson, E, Brownlee, J.M.
登録日2006-10-09
公開日2006-11-21
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Structural and thermodynamic studies of simple aldose reductase-inhibitor complexes.
Bioorg.Chem., 34, 2006
2IS7
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Crystal Structure of Aldose Reductase complexed with Dichlorophenylacetic acid
分子名称: (2,6-DICHLOROPHENYL)ACETIC ACID, Aldose reductase, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
著者Harrison, D.H.T, Milne, A, Brownlee, J.M.
登録日2006-10-16
公開日2006-11-21
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Structural and thermodynamic studies of simple aldose reductase-inhibitor complexes.
Bioorg.Chem., 34, 2006
2INE
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Crystal Structure of Aldose Reductase complexed with Phenylacetic Acid
分子名称: 2-PHENYLACETIC ACID, Aldose reductase, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
著者Harrison, D.H.T, Milne, A, Brownlee, J.M.
登録日2006-10-06
公開日2006-11-21
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structural and thermodynamic studies of simple aldose reductase-inhibitor complexes.
Bioorg.Chem., 34, 2006
2IQ0
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Crystal Structure of Aldose Reductase complexed with Hexanoic Acid
分子名称: Aldose reductase, HEXANOIC ACID, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
著者Harrison, D.H.T, Brownlee, J.M.
登録日2006-10-12
公開日2006-11-28
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Structural and thermodynamic studies of simple aldose reductase-inhibitor complexes.
Bioorg.Chem., 34, 2006
2IPW
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Crystal Structure of C298A W219Y Aldose Reductase complexed with Dichlorophenylacetic acid
分子名称: (2,6-DICHLOROPHENYL)ACETIC ACID, Aldose reductase, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
著者Harrison, D.H.T, Pape, E, Brownlee, J.M.
登録日2006-10-12
公開日2006-11-28
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structural and thermodynamic studies of simple aldose reductase-inhibitor complexes.
Bioorg.Chem., 34, 2006
2ISF
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Crystal Structure of C298A W219Y Aldose Reductase complexed with Phenylacetic Acid
分子名称: 2-PHENYLACETIC ACID, Aldose reductase, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
著者Harrison, D.H.T, Pape, E, Brownlee, J.M.
登録日2006-10-17
公開日2006-11-28
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structural and thermodynamic studies of simple aldose reductase-inhibitor complexes.
Bioorg.Chem., 34, 2006
1A7J
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PHOSPHORIBULOKINASE FROM RHODOBACTER SPHEROIDES
分子名称: PHOSPHORIBULOKINASE, SULFATE ION
著者Harrison, D.H.T, Runquist, J, Holub, A, Miziorko, H.
登録日1998-03-16
公開日1998-06-17
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献The crystal structure of phosphoribulokinase from Rhodobacter sphaeroides reveals a fold similar to that of adenylate kinase.
Biochemistry, 37, 1998
1AZ1
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ALRESTATIN BOUND TO C298A/W219Y MUTANT HUMAN ALDOSE REDUCTASE
分子名称: ALDOSE REDUCTASE, ALRESTATIN, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
著者Harrison, D.H.T, Bohren, K.M, Petsko, G.A, Ringe, D, Gabbay, K.H.
登録日1997-11-24
公開日1998-03-18
最終更新日2024-05-22
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献The alrestatin double-decker: binding of two inhibitor molecules to human aldose reductase reveals a new specificity determinant.
Biochemistry, 36, 1997
1T47
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Structure of fe2-HPPD bound to NTBC
分子名称: 2-{HYDROXY[2-NITRO-4-(TRIFLUOROMETHYL)PHENYL]METHYLENE}CYCLOHEXANE-1,3-DIONE, 4-hydroxyphenylpyruvate dioxygenase, FE (II) ION
著者Brownlee, J, Johnson-Winters, K, Harrison, D.H.T, Moran, G.R.
登録日2004-04-28
公開日2004-06-15
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Structure of the Ferrous Form of (4-Hydroxyphenyl)pyruvate Dioxygenase from Streptomyces avermitilis in Complex with the Therapeutic Herbicide, NTBC
Biochemistry, 43, 2004
1XPL
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Crystal Structure of Staphylococcus aureus HMG-COA Synthase with Acetoacetyl-COA and Acetylated Cysteine
分子名称: 3-hydroxy-3-methylglutaryl CoA synthase, ACETOACETYL-COENZYME A, SULFATE ION
著者Theisen, M.J, Misra, I, Saadat, D, Campobasso, N, Miziorko, H.M, Harrison, D.H.T.
登録日2004-10-08
公開日2004-11-02
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献3-hydroxy-3-methylglutaryl-CoA synthase intermediate complex observed in "real-time"
Proc.Natl.Acad.Sci.USA, 47, 2004
1XGD
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Apo R268A human aldose reductase
分子名称: Aldose reductase
著者Brownlee, J.M, Bohren, K.M, Milne, A.C, Gabbay, K.H, Harrison, D.H.T.
登録日2004-09-16
公開日2005-03-29
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献The structure of Apo R268A human aldose reductase: Hinges and latches that control the kinetic mechanism
Biochim.Biophys.Acta, 1748, 2005
1XPM
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Crystal Structure of Staphylococcus aureus HMG-COA Synthase with HMG-CoA and Acetoacetyl-COA and Acetylated Cysteine
分子名称: 3-HYDROXY-3-METHYLGLUTARYL-COENZYME A, 3-hydroxy-3-methylglutaryl CoA synthase, ACETOACETYL-COENZYME A, ...
著者Theisen, M.J, Misra, I, Saadat, D, Campobasso, N, Miziorko, H.M, Harrison, D.H.T.
登録日2004-10-08
公開日2004-11-02
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献3-hydroxy-3-methylglutaryl-CoA synthase intermediate complex observed in "real-time"
Proc.Natl.Acad.Sci.USA, 47, 2004
1XPK
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CRYSTAL STRUCTURE OF STAPHYLOCOCCUS AUREUS HMG-COA SYNTHASE WITH HMG-CoA AND WITH ACETOACETYL-COA AND ACETYLATED CYSTEINE
分子名称: 3-HYDROXY-3-METHYLGLUTARYL-COENZYME A, 3-hydroxy-3-methylglutaryl CoA synthase, ACETOACETYL-COENZYME A, ...
著者Theisen, M.J, Misra, I, Saadat, D, Campobasso, N, Miziorko, H.M, Harrison, D.H.T.
登録日2004-10-08
公開日2004-11-02
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献3-hydroxy-3-methylglutaryl-CoA synthase intermediate complex observed in "real-time"
Proc.Natl.Acad.Sci.USA, 47, 2004
2R5V
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Hydroxymandelate Synthase Crystal Structure
分子名称: (2S)-hydroxy(4-hydroxyphenyl)ethanoic acid, COBALT (II) ION, PCZA361.1, ...
著者Brownlee, J.M, He, P, Moran, G.R, Harrison, D.H.T.
登録日2007-09-04
公開日2008-03-18
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Two roads diverged: the structure of hydroxymandelate synthase from Amycolatopsis orientalis in complex with 4-hydroxymandelate.
Biochemistry, 47, 2008
1IK4
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X-ray Structure of Methylglyoxal Synthase from E. coli Complexed with Phosphoglycolohydroxamic Acid
分子名称: METHYLGLYOXAL SYNTHASE, PHOSPHOGLYCOLOHYDROXAMIC ACID
著者Marks, G.T, Harris, T.K, Massiah, M.A, Mildvan, A.S, Harrison, D.H.T.
登録日2001-05-02
公開日2001-09-26
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Mechanistic implications of methylglyoxal synthase complexed with phosphoglycolohydroxamic acid as observed by X-ray crystallography and NMR spectroscopy.
Biochemistry, 40, 2001
1B93
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METHYLGLYOXAL SYNTHASE FROM ESCHERICHIA COLI
分子名称: FORMIC ACID, PHOSPHATE ION, PROTEIN (METHYLGLYOXAL SYNTHASE)
著者Saadat, D, Harrison, D.H.T.
登録日1999-02-23
公開日1999-03-16
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献The crystal structure of methylglyoxal synthase from Escherichia coli.
Structure Fold.Des., 7, 1999
1EGH
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STRUCTURE OF METHYLGLYOXAL SYNTHASE COMPLEXED WITH THE COMPETITIVE INHIBITOR 2-PHOSPHOGLYCOLATE
分子名称: 2-PHOSPHOGLYCOLIC ACID, METHYLGLYOXAL SYNTHASE
著者Saadat, D, Harrison, D.H.T.
登録日2000-02-15
公開日2000-03-01
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Mirroring perfection: the structure of methylglyoxal synthase complexed with the competitive inhibitor 2-phosphoglycolate.
Biochemistry, 39, 2000

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