4BK4
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![BU of 4bk4 by Molmil](/molmil-images/mine/4bk4) | crystal structure of the human EphA4 ectodomain | Descriptor: | EPHRIN TYPE-A RECEPTOR 4 | Authors: | Seiradake, E, Schaupp, A, del Toro Ruiz, D, Kaufmann, R, Mitakidis, N, Harlos, K, Aricescu, A.R, Klein, R, Jones, E.Y. | Deposit date: | 2013-04-22 | Release date: | 2013-07-03 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (3.65 Å) | Cite: | Structurally Encoded Intraclass Differences in Epha Clusters Drive Distinct Cell Responses Nat.Struct.Mol.Biol., 20, 2013
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3ZMO
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![BU of 3zmo by Molmil](/molmil-images/mine/3zmo) | VP16, a capsid protein of bacteriophage P23-77 (VP16-type-1) | Descriptor: | CHLORIDE ION, DI(HYDROXYETHYL)ETHER, SODIUM ION, ... | Authors: | Rissanen, I, Grimes, J.M, Pawlowski, A, Mantynen, S, Harlos, K, Bamford, J.K.H, Stuart, D.I. | Deposit date: | 2013-02-11 | Release date: | 2013-05-15 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Bacteriophage P23-77 Capsid Protein Structures Reveal the Archetype of an Ancient Branch from a Major Virus Lineage. Structure, 21, 2013
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2X11
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![BU of 2x11 by Molmil](/molmil-images/mine/2x11) | Crystal structure of the complete EphA2 ectodomain in complex with ephrin A5 receptor binding domain | Descriptor: | EPHRIN TYPE-A RECEPTOR 2, EPHRIN-A5 | Authors: | Seiradake, E, Harlos, K, Sutton, G, Aricescu, A.R, Jones, E.Y. | Deposit date: | 2009-12-21 | Release date: | 2010-03-16 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (4.83 Å) | Cite: | An Extracellular Steric Seeding Mechanism for Eph-Ephrin Signalling Platform Assembly Nat.Struct.Mol.Biol., 17, 2010
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2XBO
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![BU of 2xbo by Molmil](/molmil-images/mine/2xbo) | Equine Rhinitis A Virus in Complex with its Sialic Acid Receptor | Descriptor: | N-acetyl-alpha-neuraminic acid-(2-3)-beta-D-galactopyranose-(1-4)-alpha-D-glucopyranose, P1 | Authors: | Fry, E.E, Tuthill, T.J, Harlos, K, Walter, T.S, Rowlands, D.J, Stuart, D.I. | Deposit date: | 2010-04-14 | Release date: | 2010-09-22 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (4 Å) | Cite: | The Crystal Structure of Equine Rhinitis a Virus in Complex with its Sialic Acid Receptor. J.Gen.Virol., 91, 2010
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4CS8
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![BU of 4cs8 by Molmil](/molmil-images/mine/4cs8) | Crystal structure of the asymmetric human metapneumovirus M2-1 tetramer, form 2 | Descriptor: | M2-1, ZINC ION | Authors: | Leyrat, C, Renner, M, Harlos, K, Grimes, J.M. | Deposit date: | 2014-03-05 | Release date: | 2014-05-28 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Drastic Changes in Conformational Dynamics of the Antiterminator M2-1 Regulate Transcription Efficiency in Pneumovirinae. Elife, 3, 2014
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2WJX
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![BU of 2wjx by Molmil](/molmil-images/mine/2wjx) | Crystal structure of the human ionotropic glutamate receptor GluR2 ATD region at 4.1 A resolution | Descriptor: | GLUTAMATE RECEPTOR 2 | Authors: | Clayton, A, Siebold, C, Gilbert, R.J.C, Sutton, G.C, Harlos, K, McIlhinney, R.A.J, Jones, E.Y, Aricescu, A.R. | Deposit date: | 2009-06-01 | Release date: | 2009-08-18 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (4.1 Å) | Cite: | Crystal Structure of the Glur2 Amino-Terminal Domain Provides Insights Into the Architecture and Assembly of Ionotropic Glutamate Receptors. J.Mol.Biol., 392, 2009
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4CS7
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![BU of 4cs7 by Molmil](/molmil-images/mine/4cs7) | Crystal structure of the asymmetric human metapneumovirus M2-1 tetramer, form 1 | Descriptor: | M2-1, ZINC ION | Authors: | Leyrat, C, Renner, M, Harlos, K, Grimes, J.M. | Deposit date: | 2014-03-05 | Release date: | 2014-05-28 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (2.47 Å) | Cite: | Drastic Changes in Conformational Dynamics of the Antiterminator M2-1 Regulate Transcription Efficiency in Pneumovirinae. Elife, 3, 2014
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4CS9
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![BU of 4cs9 by Molmil](/molmil-images/mine/4cs9) | Crystal structure of the asymmetric human metapneumovirus M2-1 tetramer bound to adenosine monophosphate | Descriptor: | ADENOSINE MONOPHOSPHATE, M2-1, ZINC ION | Authors: | Leyrat, C, Renner, M, Harlos, K, Grimes, J.M. | Deposit date: | 2014-03-05 | Release date: | 2014-05-28 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.01 Å) | Cite: | Drastic Changes in Conformational Dynamics of the Antiterminator M2-1 Regulate Transcription Efficiency in Pneumovirinae. Elife, 3, 2014
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4CSA
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![BU of 4csa by Molmil](/molmil-images/mine/4csa) | Crystal structure of the asymmetric human metapneumovirus M2-1 tetramer bound to a DNA 4-mer | Descriptor: | 5'-D(*AP*GP*TP*TP*AP)-3', GLYCEROL, M2-1, ... | Authors: | Leyrat, C, Renner, M, Harlos, K, Grimes, J.M. | Deposit date: | 2014-03-05 | Release date: | 2014-05-28 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.28 Å) | Cite: | Drastic Changes in Conformational Dynamics of the Antiterminator M2-1 Regulate Transcription Efficiency in Pneumovirinae. Elife, 3, 2014
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4C53
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![BU of 4c53 by Molmil](/molmil-images/mine/4c53) | Crystal Structure of Guanarito virus GP2 in the post-fusion conformation | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, PRE-GLYCOPROTEIN POLYPROTEIN GP COMPLEX, ... | Authors: | Parsy, M, Huiskonen, J.T, Harlos, K, Bowden, T.A. | Deposit date: | 2013-09-10 | Release date: | 2013-10-02 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (4.14 Å) | Cite: | Crystal Structure of Venezuelan Hemorrhagic Fever Virus Fusion Glycoprotein Reveals a Class 1 Post-Fusion Architecture with Extensive Glycosylation. J.Virol., 87, 2013
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1GP3
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![BU of 1gp3 by Molmil](/molmil-images/mine/1gp3) | Human IGF2R domain 11 | Descriptor: | CATION-INDEPENDENT MANNOSE-6-PHOSPHATE RECEPTOR | Authors: | Brown, J, Esnouf, R.M, Jones, M.A, Linnell, J, Harlos, K, Hassan, A.B, Jones, E.Y. | Deposit date: | 2001-10-29 | Release date: | 2002-02-28 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | Structure of a Functional Igf2R Fragment Determined from the Anomalous Scattering of Sulfur Embo J., 21, 2002
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1GZP
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![BU of 1gzp by Molmil](/molmil-images/mine/1gzp) | CD1b in complex with GM2 ganglioside | Descriptor: | B2-MICROGLOBULIN, DOCOSANE, DODECANE, ... | Authors: | Gadola, S.D, Zaccai, N.R, Harlos, K, Shepherd, D, Ritter, G, Schmidt, R.R, Jones, E.Y, Cerundolo, V. | Deposit date: | 2002-05-24 | Release date: | 2002-07-31 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Structure of human CD1b with bound ligands at 2.3 A, a maze for alkyl chains. Nat. Immunol., 3, 2002
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1GZQ
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![BU of 1gzq by Molmil](/molmil-images/mine/1gzq) | CD1b in complex with Phophatidylinositol | Descriptor: | 2-[(HYDROXY{[(2R,3R,5S,6R)-2,3,4,5,6-PENTAHYDROXYCYCLOHEXYL]OXY}PHOSPHORYL)OXY]-1-[(PALMITOYLOXY)METHYL]ETHYL HEPTADECANOATE, B2-MICROGLOBULIN, DOCOSANE, ... | Authors: | Gadola, S.D, Zaccai, N.R, Harlos, K, Shepherd, D, Ritter, G, Schmidt, R.R, Jones, E.Y, Cerundolo, V. | Deposit date: | 2002-05-24 | Release date: | 2002-07-31 | Last modified: | 2024-05-01 | Method: | X-RAY DIFFRACTION (2.26 Å) | Cite: | Structure of Human Cd1B with Bound Ligands at 2.3 A, a Maze for Alkyl Chains Nat.Immunol., 3, 2002
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1H4I
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![BU of 1h4i by Molmil](/molmil-images/mine/1h4i) | Methylobacterium extorquens methanol dehydrogenase | Descriptor: | CALCIUM ION, METHANOL DEHYDROGENASE SUBUNIT 1, METHANOL DEHYDROGENASE SUBUNIT 2, ... | Authors: | Ghosh, M, Anthony, C, Harlos, K, Goodwin, M.G, Blake, C. | Deposit date: | 2001-05-11 | Release date: | 2001-06-14 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (1.94 Å) | Cite: | The Refined Structure of the Quinoprotein Methanol Dehydrogenase from Methylobacterium Extorquens at 1.94 A. Structure, 3, 1995
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1GP0
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![BU of 1gp0 by Molmil](/molmil-images/mine/1gp0) | Human IGF2R domain 11 | Descriptor: | CATION-INDEPENDENT MANNOSE-6-PHOSPHATE RECEPTOR, SULFATE ION | Authors: | Brown, J, Esnouf, R.M, Jones, M.A, Linnell, J, Harlos, K, Hassan, A.B, Jones, E.Y. | Deposit date: | 2001-10-29 | Release date: | 2002-02-28 | Last modified: | 2019-04-10 | Method: | X-RAY DIFFRACTION (1.4 Å) | Cite: | Structure of a Functional Igf2R Fragment Determined from the Anomalous Scattering of Sulfur Embo J., 21, 2002
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1IPS
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![BU of 1ips by Molmil](/molmil-images/mine/1ips) | ISOPENICILLIN N SYNTHASE FROM ASPERGILLUS NIDULANS (MANGANESE COMPLEX) | Descriptor: | ISOPENICILLIN N SYNTHASE, MANGANESE (II) ION | Authors: | Roach, P.L, Clifton, I.J, Fulop, V, Harlos, K, Barton, G.J, Hajdu, J, Andersson, I, Schofield, C.J, Baldwin, J.E. | Deposit date: | 1997-03-21 | Release date: | 1998-03-25 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Crystal structure of isopenicillin N synthase is the first from a new structural family of enzymes. Nature, 375, 1995
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7BY6
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![BU of 7by6 by Molmil](/molmil-images/mine/7by6) | Plasmodium vivax cytoplasmic Phenylalanyl-tRNA synthetase in complex with BRD1389 | Descriptor: | (3S,4R,8R,9R,10S)-N-(4-cyclopropyloxyphenyl)-10-(methoxymethyl)-3,4-bis(oxidanyl)-9-[4-(2-phenylethynyl)phenyl]-1,6-diazabicyclo[6.2.0]decane-6-carboxamide, MAGNESIUM ION, Phenylalanyl-tRNA synthetase beta chain, ... | Authors: | Malhotra, N, Manmohan, S, Harlos, K, Melillo, B, Schreiber, S.L, Manickam, Y, Sharma, S. | Deposit date: | 2020-04-21 | Release date: | 2020-11-04 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.997 Å) | Cite: | Structural basis of malaria parasite phenylalanine tRNA-synthetase inhibition by bicyclic azetidines. Nat Commun, 12, 2021
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7DPI
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![BU of 7dpi by Molmil](/molmil-images/mine/7dpi) | Plasmodium falciparum cytoplasmic Phenylalanyl-tRNA synthetase in complex with BRD7929 | Descriptor: | (8R,9S,10S)-10-[(dimethylamino)methyl]-N-(4-methoxyphenyl)-9-[4-(2-phenylethynyl)phenyl]-1,6-diazabicyclo[6.2.0]decane-6-carboxamide, MAGNESIUM ION, Phenylalanine--tRNA ligase, ... | Authors: | Manmohan, S, Malhotra, N, Harlos, K, Manickam, Y, Sharma, A. | Deposit date: | 2020-12-19 | Release date: | 2022-03-23 | Last modified: | 2024-05-29 | Method: | X-RAY DIFFRACTION (3.597 Å) | Cite: | Inhibition of Plasmodium falciparum phenylalanine tRNA synthetase provides opportunity for antimalarial drug development. Structure, 30, 2022
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7EL5
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![BU of 7el5 by Molmil](/molmil-images/mine/7el5) | |
5L81
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![BU of 5l81 by Molmil](/molmil-images/mine/5l81) | |