4CSA

Crystal structure of the asymmetric human metapneumovirus M2-1 tetramer bound to a DNA 4-mer

Summary for 4CSA

• Entry DOI: 10.2210/pdb4csa/pdb
• Related: 4CS7 4CS8 4CS9
• Descriptor: M2-1, 5'-D(*AP*GP*TP*TP*AP)-3', ZINC ION, ... (6 entities in total)
• Functional Keywords: viral protein-dna complex, antiterminator, transcription elongation, rna-binding, modular protein, asymmetric tetramer, viral protein/dna
• Biological source: HUMAN METAPNEUMOVIRUS; More
• Total number of polymer chains: 5
• Total formula weight: 87610.83

Authors

Leyrat, C.,Renner, M.,Harlos, K.,Grimes, J.M. (deposition date: 2014-03-05, release date: 2014-05-28, Last modification date: 2023-12-20)

• Primary citation: Leyrat, C.,Renner, M.,Harlos, K.,Huiskonen, J.T.,Grimes, J.M.; Drastic Changes in Conformational Dynamics of the Antiterminator M2-1 Regulate Transcription Efficiency in Pneumovirinae.; Elife, 3:02674-, 2014; PubMed: 24842877; DOI: 10.7554/ELIFE.02674

Experimental method

X-RAY DIFFRACTION (2.28 Å)