2HJJ
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2hjj by Molmil](/molmil-images/mine/2hjj) | Solution NMR structure of protein ykfF from Escherichia coli. Northeast Structural Genomics target ER397. | Descriptor: | Hypothetical protein ykfF | Authors: | Swapna, G.V.T, Aramini, J.M, Zhao, L, Cunningham, K, Janjua, H, Ma, L.-C, Xiao, R, Baran, M.C, Acton, T.B, Liu, J, Rost, B, Montelione, G.T, Northeast Structural Genomics Consortium (NESG) | Deposit date: | 2006-06-30 | Release date: | 2006-08-29 | Last modified: | 2024-05-01 | Method: | SOLUTION NMR | Cite: | Solution NMR structure of protein ykfF from Escherichia coli. Northeast Structural Genomics target ER397. To be Published
|
|
2K3D
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2k3d by Molmil](/molmil-images/mine/2k3d) | Solution NMR structure of the folded 79 residue fragment of Lin0334 from Listeria innocua. Northeast Structural Genomics Consortium target LkR15 | Descriptor: | Lin0334 protein | Authors: | Ramelot, T.A, Zhao, L, Jiang, M, Foote, E.L, Xiao, R, Liu, J, Baran, M.C, Swapna, G.V.T, Acton, T.B, Rost, B, Montelione, G.T, Kennedy, M.A, Northeast Structural Genomics Consortium (NESG) | Deposit date: | 2008-05-02 | Release date: | 2008-05-13 | Last modified: | 2024-05-29 | Method: | SOLUTION NMR | Cite: | Solution NMR structure of the folded 79 residue fragment of Lin0334 from Listeria innocua. Northeast Structural Genomics Consortium target LkR15. To be Published
|
|
3U3T
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3u3t by Molmil](/molmil-images/mine/3u3t) | The S-SAD phased crystal structure of the ecto-domain of Death Receptor 6 (DR6) | Descriptor: | Tumor necrosis factor receptor superfamily member 21 | Authors: | Ru, H, Zhao, L.X, Ding, W, Jiao, L.Y, Shaw, N, Zhang, L.G, Hung, L.W, Matsugaki, N, Wakatsuki, S, Liu, Z.J. | Deposit date: | 2011-10-06 | Release date: | 2012-05-02 | Last modified: | 2012-07-11 | Method: | X-RAY DIFFRACTION (3.21 Å) | Cite: | S-SAD phasing study of death receptor 6 and its solution conformation revealed by SAXS Acta Crystallogr.,Sect.D, 68, 2012
|
|
9IY2
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 9iy2 by Molmil](/molmil-images/mine/9iy2) | Immune complex of HEV-E2s, nAb 8C11 and nAb 8H3 | Descriptor: | Heavy Chain of mAb 8C11, Heavy Chain of mAb 8H3, Light Chain of mAb 8C11, ... | Authors: | Minghua, Z, Lizhi, Z, Ying, G, Shaowei, L. | Deposit date: | 2024-07-29 | Release date: | 2024-08-28 | Last modified: | 2024-09-04 | Method: | X-RAY DIFFRACTION (3.476 Å) | Cite: | Structural basis for the synergetic neutralization of hepatitis E virus by antibody-antibody interaction To Be Published
|
|
3CPK
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3cpk by Molmil](/molmil-images/mine/3cpk) | Crystal structure of the Q7W7N7_BORPA protein from Bordetella parapertussis. Northeast Structural Genomics Consortium target BeR31 | Descriptor: | Uncharacterized protein Q7W7N7_BORPA | Authors: | Vorobiev, S.M, Abashidze, M, Seetharaman, J, Zhao, L, Janjua, H, Xiao, R, Acton, T.B, Montelione, G.T, Tong, L, Hunt, J.F, Northeast Structural Genomics Consortium (NESG) | Deposit date: | 2008-03-31 | Release date: | 2008-04-15 | Last modified: | 2017-10-25 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Crystal structure of the Q7W7N7_BORPA protein from Bordetella parapertussis. To be Published
|
|
3MGD
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3mgd by Molmil](/molmil-images/mine/3mgd) | Crystal Structure of predicted acetyltransferase with acetyl-CoA from Clostridium acetobutylicum at the resolution 1.9A, Northeast Structural Genomics Consortium Target CaR165 | Descriptor: | ACETYL COENZYME *A, Predicted acetyltransferase | Authors: | Kuzin, A, Chen, Y, Seetharaman, J, Sahdev, S, Xiao, R, Ciccosanti, C, Zhao, L, Everett, J.K, Nair, R, Acton, T.B, Rost, B, Montelione, G.T, Hunt, J.F, Tong, L, Northeast Structural Genomics Consortium (NESG) | Deposit date: | 2010-04-05 | Release date: | 2010-04-28 | Last modified: | 2019-07-17 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Northeast Structural Genomics Consortium Target CaR165 To be published
|
|
4FIB
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4fib by Molmil](/molmil-images/mine/4fib) | Crystal structure of the ydhK protein from Bacillus subtilis. Northeast Structural Genomics Consortium Target SR518A. | Descriptor: | Uncharacterized protein ydhK | Authors: | Vorobiev, S, Abashidze, M, Seetharaman, J, Mao, M, Xiao, R, Maglaqui, M, Owens, L.A, Cunningham, K, Zhao, L, Everett, J.K, Acton, T.B, Montelione, G.T, Tong, L, Hunt, J.F, Northeast Structural Genomics Consortium (NESG) | Deposit date: | 2012-06-08 | Release date: | 2012-06-20 | Method: | X-RAY DIFFRACTION (1.997 Å) | Cite: | Crystal structure of the ydhK protein from Bacillus subtilis. To be Published
|
|
4IHA
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4iha by Molmil](/molmil-images/mine/4iha) | Crystal structure of rice DWARF14 (D14) in complex with a GR24 hydrolysis intermediate | Descriptor: | (2R,3R)-2,4,4-trihydroxy-3-methylbutanal, Dwarf 88 esterase | Authors: | Zhou, X.E, Zhao, L.-H, Wu, Z.-S, Yi, W, Li, S, Li, Y, Xu, Y, Xu, T.-H, Liu, Y, Chen, R.-Z, Kovach, A, Kang, Y, Hou, L, He, Y, Zhang, C, Melcher, K, Xu, H.E. | Deposit date: | 2012-12-18 | Release date: | 2013-01-23 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (1.55 Å) | Cite: | Crystal structures of two phytohormone signal-transducing alpha / beta hydrolases: karrikin-signaling KAI2 and strigolactone-signaling DWARF14. Cell Res., 23, 2013
|
|
4DLH
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4dlh by Molmil](/molmil-images/mine/4dlh) | Crystal Structure of the protein Q9HRE7 from Halobacterium salinarium at the resolution 1.9A, Northeast Structural Genomics Consortium (NESG) Target HsR50 | Descriptor: | uncharacterized protein | Authors: | Kuzin, A, Chen, Y, Seetharaman, J, Mao, M, Xiao, R, Ciccosanti, C, Zhao, L, Everett, J.K, Nair, R, Acton, T.B, Rost, B, Montelione, G.T, Hunt, J.F, Tong, L, Northeast Structural Genomics Consortium (NESG) | Deposit date: | 2012-02-06 | Release date: | 2012-02-15 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Northeast Structural Genomics Consortium Target HsR50 To be Published
|
|
4IH4
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4ih4 by Molmil](/molmil-images/mine/4ih4) | Crystal structure of Arabidopsis DWARF14 orthologue, AtD14 | Descriptor: | AT3g03990/T11I18_10 | Authors: | Zhou, X.E, Zhao, L.-H, Wu, Z.-S, Yi, W, Li, S, Li, Y, Xu, Y, Xu, T.-H, Liu, Y, Chen, R.-Z, Kovach, A, Kang, Y, Hou, L, He, Y, Zhang, C, Melcher, K, Xu, H.E. | Deposit date: | 2012-12-18 | Release date: | 2013-01-30 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (3.5 Å) | Cite: | Crystal structures of two phytohormone signal-transducing alpha / beta hydrolases: karrikin-signaling KAI2 and strigolactone-signaling DWARF14. Cell Res., 23, 2013
|
|
2NYS
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2nys by Molmil](/molmil-images/mine/2nys) | X-ray Crystal Structure of Protein AGR_C_3712 from Agrobacterium tumefaciens. Northeast Structural Genomics Consortium Target AtR88. | Descriptor: | AGR_C_3712p | Authors: | Vorobiev, S.M, Abashidze, M, Seetharaman, J, Zhao, L, Ma, L.C, Cunningham, K, Nwosu, C, Xiao, R, Acton, T.B, Montelione, G.T, Tong, L, Hunt, J.F, Northeast Structural Genomics Consortium (NESG) | Deposit date: | 2006-11-21 | Release date: | 2006-12-05 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Crystal structure of the hypothetical protein AGR_C_3712 from Agrobacterium tumefaciens. To be Published
|
|
2KFP
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2kfp by Molmil](/molmil-images/mine/2kfp) | Solution NMR structure of PSPTO_3016 from Pseudomonas syringae. Northeast Structural Genomics Consortium target PsR293. | Descriptor: | PSPTO_3016 protein | Authors: | Feldmann, E.A, Ramelot, T.A, Zhao, L, Hamilton, K, Ciccosanti, C, Xiao, R, Nair, R, Everett, J.K, Swapna, G, Acton, T.B, Rost, B, Montelione, G.T, Kennedy, M.A, Northeast Structural Genomics Consortium (NESG) | Deposit date: | 2009-02-24 | Release date: | 2009-03-24 | Last modified: | 2024-05-08 | Method: | SOLUTION NMR | Cite: | Solution NMR and X-ray crystal structures of Pseudomonas syringae Pspto_3016 from protein domain family PF04237 (DUF419) adopt a "double wing" DNA binding motif. J.Struct.Funct.Genom., 13, 2012
|
|
2P7N
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2p7n by Molmil](/molmil-images/mine/2p7n) | Crystal structure of the Pathogenicity island 1 effector protein from Chromobacterium violaceum. Northeast Structural Genomics Consortium (NESGC) target CvR69. | Descriptor: | Pathogenicity island 1 effector protein | Authors: | Benach, J, Abashidze, M, Seetharaman, J, Zhao, L, Janjua, H, Cunningham, K, Ma, L.C, Xiao, R, Liu, J, Baran, M.C, Acton, T.B, Rost, B, Montelione, G.T, Hunt, J.F, Tong, L, Northeast Structural Genomics Consortium (NESG) | Deposit date: | 2007-03-20 | Release date: | 2007-04-03 | Last modified: | 2017-10-18 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Crystal structure of the Pathogenicity island 1 effector protein from Chromobacterium violaceum. Northeast Structural Genomics Consortium (NESGC) target CvR69. To be Published
|
|
4IH1
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4ih1 by Molmil](/molmil-images/mine/4ih1) | Crystal structure of Karrikin Insensitive 2 (KAI2) from Arabidopsis thaliana | Descriptor: | Hydrolase, alpha/beta fold family protein | Authors: | Zhou, X.E, Zhao, L.-H, Wu, Z.-S, Yi, W, Li, S, Li, Y, Xu, Y, Xu, T.-H, Liu, Y, Chen, R.-Z, Kovach, A, Kang, Y, Hou, L, He, Y, Zhang, C, Melcher, K, Xu, H.E. | Deposit date: | 2012-12-18 | Release date: | 2013-01-30 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (1.55 Å) | Cite: | Crystal structures of two phytohormone signal-transducing alpha / beta hydrolases: karrikin-signaling KAI2 and strigolactone-signaling DWARF14. Cell Res., 23, 2013
|
|
4IH9
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4ih9 by Molmil](/molmil-images/mine/4ih9) | Crystal structure of rice DWARF14 (D14) | Descriptor: | Dwarf 88 esterase | Authors: | Zhou, X.E, Zhao, L.-H, Wu, Z.-S, Yi, W, Li, S, Li, Y, Xu, Y, Xu, T.-H, Liu, Y, Chen, R.-Z, Kovach, A, Kang, Y, Hou, L, He, Y, Zhang, C, Melcher, K, Xu, H.E. | Deposit date: | 2012-12-18 | Release date: | 2013-01-30 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (1.55 Å) | Cite: | Crystal structures of two phytohormone signal-transducing alpha / beta hydrolases: karrikin-signaling KAI2 and strigolactone-signaling DWARF14. Cell Res., 23, 2013
|
|
7DUQ
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7duq by Molmil](/molmil-images/mine/7duq) | Cryo-EM structure of the compound 2 and GLP-1-bound human GLP-1 receptor-Gs complex | Descriptor: | CHOLESTEROL, Glucagon-like peptide 1, Glucagon-like peptide 1 receptor, ... | Authors: | Cong, Z, Chen, L, Ma, H, Zhou, Q, Zou, X, Ye, C, Dai, A, Liu, Q, Huang, W, Sun, X, Wang, X, Xu, P, Zhao, L, Xia, T, Zhong, W, Yang, D, Xu, H.E, Zhang, Y, Wang, M. | Deposit date: | 2021-01-11 | Release date: | 2021-07-14 | Method: | ELECTRON MICROSCOPY (2.5 Å) | Cite: | Molecular insights into ago-allosteric modulation of the human glucagon-like peptide-1 receptor. Nat Commun, 12, 2021
|
|
7DUR
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7dur by Molmil](/molmil-images/mine/7dur) | Cryo-EM structure of the compound 2-bound human GLP-1 receptor-Gs complex | Descriptor: | CHOLESTEROL, Glucagon-like peptide 1 receptor, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... | Authors: | Cong, Z, Chen, L, Ma, H, Zhou, Q, Zou, X, Ye, C, Dai, A, Liu, Q, Huang, W, Sun, X, Wang, X, Xu, P, Zhao, L, Xia, T, Zhong, W, Yang, D, Xu, H.E, Zhang, Y, Wang, M. | Deposit date: | 2021-01-11 | Release date: | 2021-08-11 | Method: | ELECTRON MICROSCOPY (3.3 Å) | Cite: | Molecular insights into ago-allosteric modulation of the human glucagon-like peptide-1 receptor. Nat Commun, 12, 2021
|
|
7EVM
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7evm by Molmil](/molmil-images/mine/7evm) | Cryo-EM structure of the compound 2-bound human GLP-1 receptor-Gs complex | Descriptor: | CHOLESTEROL, Glucagon-like peptide 1 receptor, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... | Authors: | Cong, Z, Chen, L, Ma, H, Zhou, Q, Zou, X, Ye, C, Dai, A, Liu, Q, Huang, W, Sun, X, Wang, X, Xu, P, Zhao, L, Xia, T, Zhong, W, Yang, D, Xu, H.E, Zhang, Y, Wang, M. | Deposit date: | 2021-05-21 | Release date: | 2021-08-11 | Method: | ELECTRON MICROSCOPY (2.5 Å) | Cite: | Molecular insights into ago-allosteric modulation of the human glucagon-like peptide-1 receptor. Nat Commun, 12, 2021
|
|
1T6M
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1t6m by Molmil](/molmil-images/mine/1t6m) | X-ray Structure of the R70D PI-PLC enzyme: Insight into the role of calcium and surrounding amino acids on active site geometry and catalysis. | Descriptor: | 1-phosphatidylinositol phosphodiesterase, CALCIUM ION | Authors: | Apiyo, D, Zhao, L, Tsai, M.-D, Selby, T.L. | Deposit date: | 2004-05-06 | Release date: | 2005-08-16 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.107 Å) | Cite: | X-ray Structure of the R69D Phosphatidylinositol-Specific Phospholipase C Enzyme: Insight into the Role of Calcium and Surrounding Amino Acids in Active Site Geometry and Catalysis. Biochemistry, 44, 2005
|
|
2KCQ
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2kcq by Molmil](/molmil-images/mine/2kcq) | Solution structure of protein SRU_2040 from Salinibacter ruber (strain DSM 13855) . Northeast Structural Genomics Consortium target SrR106 | Descriptor: | Mov34/MPN/PAD-1 family | Authors: | Wu, Y, Eletsky, A, Zhao, L, Hua, J, Sukumaran, D, Jiang, M, Foote, E.L, Xiao, R, Nair, R, Everett, J.K, Swapna, G, Acton, T.B, Rost, B, Montelione, G.T, Szyperski, T, Northeast Structural Genomics Consortium (NESG) | Deposit date: | 2008-12-28 | Release date: | 2009-02-24 | Last modified: | 2024-05-08 | Method: | SOLUTION NMR | Cite: | Solution structure of protein SRU_2040 from Salinibacter ruber (strain DSM 13855). Northeast Structural Genomics Consortium target SrR106 To be Published
|
|
3G77
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3g77 by Molmil](/molmil-images/mine/3g77) | Bacterial cytosine deaminase V152A/F316C/D317G mutant | Descriptor: | Cytosine deaminase, FE (III) ION | Authors: | Stoddard, B, Zhao, L. | Deposit date: | 2009-02-09 | Release date: | 2009-09-22 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Bacterial cytosine deaminase mutants created by molecular engineering show improved 5-fluorocytosine-mediated cell killing in vitro and in vivo. Cancer Res., 69, 2009
|
|
2F4J
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2f4j by Molmil](/molmil-images/mine/2f4j) | Structure of the Kinase Domain of an Imatinib-Resistant Abl Mutant in Complex with the Aurora Kinase Inhibitor VX-680 | Descriptor: | CYCLOPROPANECARBOXYLIC ACID {4-[4-(4-METHYL-PIPERAZIN-1-YL)-6-(5-METHYL-2H-PYRAZOL-3-YLAMINO)-PYRIMIDIN-2-YLSULFANYL]-PHENYL}-AMIDE, Proto-oncogene tyrosine-protein kinase ABL1 | Authors: | Young, M.A, Shah, N.P, Chao, L.H, Zarrinkar, P, Sawyers, P, Kuriyan, J. | Deposit date: | 2005-11-23 | Release date: | 2006-01-24 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (1.91 Å) | Cite: | Structure of the kinase domain of an imatinib-resistant Abl mutant in complex with the Aurora kinase inhibitor VX-680. Cancer Res., 66, 2006
|
|
7F16
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7f16 by Molmil](/molmil-images/mine/7f16) | Cryo-EM structure of parathyroid hormone receptor type 2 in complex with a tuberoinfundibular peptide of 39 residues and G protein | Descriptor: | CHOLESTEROL, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... | Authors: | Wang, X, Cheng, X, Zhao, L.H, Wang, Y, Ye, C, Zou, X, Dai, A, Cong, Z, Chen, J, Zhou, Q, Xia, T, Jiang, H, Xu, H.E, Yang, D, Wang, M.W. | Deposit date: | 2021-06-08 | Release date: | 2021-08-18 | Method: | ELECTRON MICROSCOPY (2.8 Å) | Cite: | Molecular insights into differentiated ligand recognition of the human parathyroid hormone receptor 2. Proc.Natl.Acad.Sci.USA, 118, 2021
|
|
8FEH
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8feh by Molmil](/molmil-images/mine/8feh) | |
4JBK
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4jbk by Molmil](/molmil-images/mine/4jbk) | Molecular basis for abrogation of activation of pro-inflammatory cytokines | Descriptor: | DNA (5'-D(P*GP*GP*AP*AP*TP*TP*AP*TP*AP*AP*TP*TP*CP*C)-3'), Interferon-activable protein 202 | Authors: | Ru, H, Ni, X, Crowley, C, Zhao, L, Ding, W, Hung, L.-W, Shaw, N, Cheng, G, Liu, Z.-J. | Deposit date: | 2013-02-19 | Release date: | 2013-06-26 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.963 Å) | Cite: | Structural basis for termination of AIM2-mediated signaling by p202 Cell Res., 23, 2013
|
|