2YMA
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![BU of 2yma by Molmil](/molmil-images/mine/2yma) | X-ray structure of the Yos9 dimerization domain | Descriptor: | PROTEIN OS-9 HOMOLOG | Authors: | Hanna, J, Schuetz, A, Zimmermann, F, Behlke, J, Sommer, T, Heinemann, U. | Deposit date: | 2011-06-07 | Release date: | 2012-01-25 | Last modified: | 2024-05-01 | Method: | X-RAY DIFFRACTION (2.545 Å) | Cite: | Structural and Biochemical Basis of Yos9 Protein Dimerization and Possible Contribution to Self-Association of 3-Hydroxy-3-Methylglutaryl-Coenzyme a Reductase Degradation Ubiquitin-Ligase Complex. J.Biol.Chem., 287, 2012
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5IJ4
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![BU of 5ij4 by Molmil](/molmil-images/mine/5ij4) | Solution structure of AN1-type zinc finger domain from Cuz1 (Cdc48 associated ubiquitin-like/zinc-finger protein-1) | Descriptor: | CDC48-associated ubiquitin-like/zinc finger protein 1, ZINC ION | Authors: | Sun, Z.-Y.J, Hanna, J, Wagner, G, Bhanu, M.K, Allan, M, Arthanari, H. | Deposit date: | 2016-03-01 | Release date: | 2016-10-05 | Last modified: | 2024-05-01 | Method: | SOLUTION NMR | Cite: | Solution Structure of the Cuz1 AN1 Zinc Finger Domain: An Exposed LDFLP Motif Defines a Subfamily of AN1 Proteins. Plos One, 11, 2016
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7TEO
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![BU of 7teo by Molmil](/molmil-images/mine/7teo) | Cryo-EM structure of the 20S Alpha 3 Deletion proteasome core particle in complex with FUB1 | Descriptor: | Proteasome subunit alpha type-1, Proteasome subunit alpha type-2, Proteasome subunit alpha type-4, ... | Authors: | Walsh Jr, R.M, Rawson, S, Schnell, H.M, Hanna, J. | Deposit date: | 2022-01-05 | Release date: | 2022-08-10 | Last modified: | 2024-02-28 | Method: | ELECTRON MICROSCOPY (2.97 Å) | Cite: | Yeast PI31 inhibits the proteasome by a direct multisite mechanism. Nat.Struct.Mol.Biol., 29, 2022
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7TEJ
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![BU of 7tej by Molmil](/molmil-images/mine/7tej) | Cryo-EM structure of the 20S Alpha 3 Deletion proteasome core particle | Descriptor: | Proteasome subunit alpha type-1, Proteasome subunit alpha type-2, Proteasome subunit alpha type-4, ... | Authors: | Walsh Jr, R.M, Rawson, S, Schnell, H.M, Hanna, J. | Deposit date: | 2022-01-05 | Release date: | 2022-08-10 | Last modified: | 2024-02-28 | Method: | ELECTRON MICROSCOPY (2.74 Å) | Cite: | Yeast PI31 inhibits the proteasome by a direct multisite mechanism. Nat.Struct.Mol.Biol., 29, 2022
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7LS5
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![BU of 7ls5 by Molmil](/molmil-images/mine/7ls5) | Cryo-EM structure of the Pre3-1 20S proteasome core particle | Descriptor: | Proteasome subunit alpha type-1, Proteasome subunit alpha type-2, Proteasome subunit alpha type-3, ... | Authors: | Schnell, H.M, Walsh Jr, R.M, Rawson, S, Hanna, J.W. | Deposit date: | 2021-02-17 | Release date: | 2021-04-14 | Last modified: | 2024-03-06 | Method: | ELECTRON MICROSCOPY (2.74 Å) | Cite: | Structures of chaperone-associated assembly intermediates reveal coordinated mechanisms of proteasome biogenesis. Nat.Struct.Mol.Biol., 28, 2021
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7LS6
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![BU of 7ls6 by Molmil](/molmil-images/mine/7ls6) | Cryo-EM structure of Pre-15S proteasome core particle assembly intermediate purified from Pre3-1 proteasome mutant (G34D) | Descriptor: | Proteasome assembly chaperone 2, Proteasome chaperone 1, Proteasome maturation factor UMP1, ... | Authors: | Schnell, H.M, Walsh Jr, R.M, Rawson, S, Hanna, J.W. | Deposit date: | 2021-02-17 | Release date: | 2021-04-14 | Last modified: | 2024-03-06 | Method: | ELECTRON MICROSCOPY (3.17 Å) | Cite: | Structures of chaperone-associated assembly intermediates reveal coordinated mechanisms of proteasome biogenesis. Nat.Struct.Mol.Biol., 28, 2021
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7LSX
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![BU of 7lsx by Molmil](/molmil-images/mine/7lsx) | Cryo-EM structure of 13S proteasome core particle assembly intermediate purified from Pre3-1 proteasome mutant (G34D) | Descriptor: | Proteasome assembly chaperone 2, Proteasome chaperone 1, Proteasome maturation factor UMP1, ... | Authors: | Schnell, H.M, Walsh Jr, R.M, Rawson, S, Hanna, J.W. | Deposit date: | 2021-02-18 | Release date: | 2021-04-14 | Last modified: | 2024-03-06 | Method: | ELECTRON MICROSCOPY (3.61 Å) | Cite: | Structures of chaperone-associated assembly intermediates reveal coordinated mechanisms of proteasome biogenesis. Nat.Struct.Mol.Biol., 28, 2021
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8QYO
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![BU of 8qyo by Molmil](/molmil-images/mine/8qyo) | Human proteasome 20S core particle | Descriptor: | Proteasome subunit alpha type-1, Proteasome subunit alpha type-2, Proteasome subunit alpha type-3, ... | Authors: | Schulman, B.A, Hanna, J.W, Harper, J.W, Adolf, F, Du, J, Rawson, S.D, Walsh Jr, R.M, Goodall, E.A. | Deposit date: | 2023-10-26 | Release date: | 2024-02-21 | Last modified: | 2024-04-17 | Method: | ELECTRON MICROSCOPY (2.84 Å) | Cite: | Visualizing chaperone-mediated multistep assembly of the human 20S proteasome. Nat.Struct.Mol.Biol., 2024
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8QYM
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![BU of 8qym by Molmil](/molmil-images/mine/8qym) | Human 20S proteasome assembly intermediate structure 3 | Descriptor: | Proteasome assembly chaperone 1, Proteasome assembly chaperone 2, Proteasome maturation protein, ... | Authors: | Schulman, B.A, Hanna, J.W, Harper, J.W, Adolf, F, Du, J, Rawson, S.D, Walsh Jr, R.M, Goodall, E.A. | Deposit date: | 2023-10-26 | Release date: | 2024-02-21 | Last modified: | 2024-04-17 | Method: | ELECTRON MICROSCOPY (2.73 Å) | Cite: | Visualizing chaperone-mediated multistep assembly of the human 20S proteasome. Nat.Struct.Mol.Biol., 2024
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8QYS
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![BU of 8qys by Molmil](/molmil-images/mine/8qys) | Human preholo proteasome 20S core particle | Descriptor: | Proteasome assembly chaperone 1, Proteasome assembly chaperone 2, Proteasome maturation protein, ... | Authors: | Schulman, B.A, Hanna, J.W, Harper, J.W, Adolf, F, Du, J, Rawson, S.D, Walsh Jr, R.M, Goodall, E.A. | Deposit date: | 2023-10-26 | Release date: | 2024-02-21 | Last modified: | 2024-04-17 | Method: | ELECTRON MICROSCOPY (3.89 Å) | Cite: | Visualizing chaperone-mediated multistep assembly of the human 20S proteasome. Nat.Struct.Mol.Biol., 2024
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8QZ9
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![BU of 8qz9 by Molmil](/molmil-images/mine/8qz9) | Human 20S proteasome assembly intermediate structure 4 | Descriptor: | Proteasome assembly chaperone 1, Proteasome assembly chaperone 2, Proteasome maturation protein, ... | Authors: | Schulman, B.A, Hanna, J.W, Harper, J.W, Adolf, F, Du, J, Rawson, S.D, Walsh Jr, R.M, Goodall, E.A. | Deposit date: | 2023-10-26 | Release date: | 2024-02-21 | Last modified: | 2024-04-17 | Method: | ELECTRON MICROSCOPY (2.95 Å) | Cite: | Visualizing chaperone-mediated multistep assembly of the human 20S proteasome. Nat.Struct.Mol.Biol., 2024
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8QYN
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![BU of 8qyn by Molmil](/molmil-images/mine/8qyn) | Human 20S proteasome assembly intermediate structure 5 | Descriptor: | Proteasome assembly chaperone 1, Proteasome assembly chaperone 2, Proteasome maturation protein, ... | Authors: | Schulman, B.A, Hanna, J.W, Harper, J.W, Adolf, F, Du, J, Rawson, S.D, Walsh Jr, R.M, Goodall, E.A. | Deposit date: | 2023-10-26 | Release date: | 2024-02-21 | Last modified: | 2024-04-17 | Method: | ELECTRON MICROSCOPY (2.88 Å) | Cite: | Visualizing chaperone-mediated multistep assembly of the human 20S proteasome. Nat.Struct.Mol.Biol., 2024
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8QYL
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![BU of 8qyl by Molmil](/molmil-images/mine/8qyl) | Human 20S proteasome assembly intermediate structure 2 | Descriptor: | Proteasome assembly chaperone 1, Proteasome assembly chaperone 2, Proteasome maturation protein, ... | Authors: | Schulman, B.A, Hanna, J.W, Harper, J.W, Adolf, F, Du, J, Rawson, S.D, Walsh Jr, R.M, Goodall, E.A. | Deposit date: | 2023-10-26 | Release date: | 2024-02-21 | Last modified: | 2024-04-17 | Method: | ELECTRON MICROSCOPY (2.67 Å) | Cite: | Visualizing chaperone-mediated multistep assembly of the human 20S proteasome. Nat.Struct.Mol.Biol., 2024
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8QYJ
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![BU of 8qyj by Molmil](/molmil-images/mine/8qyj) | Human 20S proteasome assembly structure 1 | Descriptor: | Proteasome assembly chaperone 1, Proteasome assembly chaperone 2, Proteasome assembly chaperone 3, ... | Authors: | Schulman, B.A, Hanna, J.W, Harper, J.W, Adolf, F, Du, J, Rawson, S.D, Walsh Jr, R.M, Goodall, E.A. | Deposit date: | 2023-10-26 | Release date: | 2024-02-21 | Last modified: | 2024-04-17 | Method: | ELECTRON MICROSCOPY (2.73 Å) | Cite: | Visualizing chaperone-mediated multistep assembly of the human 20S proteasome. Nat.Struct.Mol.Biol., 2024
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8T0M
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![BU of 8t0m by Molmil](/molmil-images/mine/8t0m) | Proteasome 20S core particle from Pre1-1 Pre4-1 Double mutant | Descriptor: | Proteasome subunit alpha type-1, Proteasome subunit alpha type-2, Proteasome subunit alpha type-3, ... | Authors: | Walsh Jr, R.M, Rawson, S, Schnell, H, Velez, B, Hanna, J. | Deposit date: | 2023-06-01 | Release date: | 2023-09-06 | Last modified: | 2023-10-25 | Method: | ELECTRON MICROSCOPY (2.4 Å) | Cite: | Structure of the preholoproteasome reveals late steps in proteasome core particle biogenesis. Nat.Struct.Mol.Biol., 30, 2023
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8T08
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![BU of 8t08 by Molmil](/molmil-images/mine/8t08) | Preholo-Proteasome from Pre1-1 Pre4-1 Double Mutant | Descriptor: | Proteasome assembly chaperone 2, Proteasome chaperone 1, Proteasome maturation factor UMP1, ... | Authors: | Walsh Jr, R.M, Rawson, S, Schnell, H, Velez, B, Hanna, J. | Deposit date: | 2023-05-31 | Release date: | 2023-09-06 | Last modified: | 2023-10-25 | Method: | ELECTRON MICROSCOPY (3 Å) | Cite: | Structure of the preholoproteasome reveals late steps in proteasome core particle biogenesis. Nat.Struct.Mol.Biol., 30, 2023
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8U6Y
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![BU of 8u6y by Molmil](/molmil-images/mine/8u6y) | Preholo-Proteasome from Beta 3 D205 deletion | Descriptor: | Proteasome assembly chaperone 2, Proteasome chaperone 1, Proteasome maturation factor UMP1, ... | Authors: | Walsh Jr, R.M, Rawson, S, Velez, B, Blickling, M, Razi, A, Hanna, J. | Deposit date: | 2023-09-14 | Release date: | 2024-04-17 | Last modified: | 2024-04-24 | Method: | ELECTRON MICROSCOPY (2.8 Å) | Cite: | Mechanism of autocatalytic activation during proteasome assembly. Nat.Struct.Mol.Biol., 2024
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8U7U
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![BU of 8u7u by Molmil](/molmil-images/mine/8u7u) | Proteasome 20S Core Particle from Beta 3 D205 deletion | Descriptor: | Proteasome subunit alpha type-1, Proteasome subunit alpha type-2, Proteasome subunit alpha type-3, ... | Authors: | Walsh Jr, R.M, Rawson, S, Velez, B, Blickling, M, Razi, A, Hanna, J. | Deposit date: | 2023-09-15 | Release date: | 2024-04-17 | Last modified: | 2024-04-24 | Method: | ELECTRON MICROSCOPY (2.16 Å) | Cite: | Mechanism of autocatalytic activation during proteasome assembly. Nat.Struct.Mol.Biol., 2024
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1W2S
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![BU of 1w2s by Molmil](/molmil-images/mine/1w2s) | Solution structure of CR2 SCR 1-2 in its complex with C3d by X-ray scattering | Descriptor: | COMPLEMENT C3 PRECURSOR, COMPLEMENT RECEPTOR TYPE 2 PRECURSOR, | Authors: | Gilbert, H.E, Hannan, J.P, Holers, V.M, Perkins, S.J. | Deposit date: | 2004-07-08 | Release date: | 2005-09-29 | Last modified: | 2024-05-08 | Method: | SOLUTION SCATTERING | Cite: | Solution Structure of the Complex between Cr2 Scr 1-2 and C3D of Human Complement: An X-Ray Scattering and Sedimentation Modelling Study. J.Mol.Biol., 346, 2005
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1W2R
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![BU of 1w2r by Molmil](/molmil-images/mine/1w2r) | Solution structure of CR2 SCR 1-2 by X-ray scattering | Descriptor: | COMPLEMENT RECEPTOR TYPE 2 PRECURSOR, | Authors: | Gilbert, H.E, Hannan, J.P, Holers, V.M, Perkins, S.J. | Deposit date: | 2004-07-08 | Release date: | 2005-09-29 | Last modified: | 2024-05-08 | Method: | SOLUTION SCATTERING | Cite: | Solution Structure of the Complex between Cr2 Scr 1-2 and C3D of Human Complement: An X-Ray Scattering and Sedimentation Modelling Study. J.Mol.Biol., 346, 2005
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3R62
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![BU of 3r62 by Molmil](/molmil-images/mine/3r62) | Structure of complement regulator Factor H mutant, T1184R. | Descriptor: | Complement factor H, GLYCEROL | Authors: | Morgan, H.P, Jiang, J, Herbert, A.P, Kavanagh, D, Uhran, D, Barlow, P.N, Hannan, J.P. | Deposit date: | 2011-03-21 | Release date: | 2011-06-29 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (1.52 Å) | Cite: | Crystallographic determination of the disease-associated T1184R variant of the complement Factor H. Acta Crystallogr.,Sect.D, 67, 2011
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3OXU
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![BU of 3oxu by Molmil](/molmil-images/mine/3oxu) | Complement components factor H CCP19-20 and C3d in complex | Descriptor: | Complement C3, GLYCEROL, HF protein | Authors: | Morgan, H.P, Schmidt, C.Q, Guariento, M, Gillespie, D, Herbert, A.P, Mertens, H, Blaum, B.S, Svergun, D, Johansson, C.M, Uhrin, D, Barlow, P.N, Hannan, J.P. | Deposit date: | 2010-09-22 | Release date: | 2011-02-16 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Structural basis for engagement by complement factor H of C3b on a self surface. Nat.Struct.Mol.Biol., 18, 2011
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3RJ3
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![BU of 3rj3 by Molmil](/molmil-images/mine/3rj3) | |
3SW0
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![BU of 3sw0 by Molmil](/molmil-images/mine/3sw0) | Structure of the C-terminal region (modules 18-20) of complement regulator Factor H | Descriptor: | Complement factor H, GLYCEROL, PHOSPHATE ION | Authors: | Morgan, H.P, Guariento, M, Schmidt, C.Q, Barlow, P.N, Hannan, J.P. | Deposit date: | 2011-07-13 | Release date: | 2012-03-14 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Structural Analysis of the C-Terminal Region (Modules 18-20) of Complement Regulator Factor H (FH). Plos One, 7, 2012
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