6VQX
 
 | | Type I-F CRISPR-Csy complex with its inhibitor AcrF6 | | Descriptor: | AcrF6, CRISPR-associated endonuclease Cas6/Csy4, CRISPR-associated protein Csy1, ... | | Authors: | Zhang, K, Li, S, Pintilie, G, Zhu, Y, Huang, Z, Chiu, W. | | Deposit date: | 2020-02-06 | | Release date: | 2020-03-11 | | Last modified: | 2024-03-06 | | Method: | ELECTRON MICROSCOPY (3.15 Å) | | Cite: | Inhibition mechanisms of AcrF9, AcrF8, and AcrF6 against type I-F CRISPR-Cas complex revealed by cryo-EM.
Proc.Natl.Acad.Sci.USA, 117, 2020
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6VQV
 | | Type I-F CRISPR-Csy complex with its inhibitor AcrF9 | | Descriptor: | AcrF9, CRISPR-associated endonuclease Cas6/Csy4, CRISPR-associated protein Csy1, ... | | Authors: | Zhang, K, Li, S, Pintilie, G, Zhu, Y, Huang, Z, Chiu, W. | | Deposit date: | 2020-02-06 | | Release date: | 2020-03-11 | | Last modified: | 2024-03-06 | | Method: | ELECTRON MICROSCOPY (2.57 Å) | | Cite: | Inhibition mechanisms of AcrF9, AcrF8, and AcrF6 against type I-F CRISPR-Cas complex revealed by cryo-EM.
Proc.Natl.Acad.Sci.USA, 117, 2020
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3C4F
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3J1F
 | | Cryo-EM structure of 9-fold symmetric rATcpn-beta in ATP-binding state | | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, Chaperonin beta subunit, MAGNESIUM ION | | Authors: | Zhang, K, Wang, L, Liu, Y.X, Wang, X, Gao, B, Hu, Z.J, Ji, G, Chan, K.Y, Schulten, K, Dong, Z.Y, Sun, F. | | Deposit date: | 2012-02-06 | | Release date: | 2013-08-07 | | Last modified: | 2024-02-21 | | Method: | ELECTRON MICROSCOPY (6.2 Å) | | Cite: | Flexible interwoven termini determine the thermal stability of thermosomes.
Protein Cell, 4, 2013
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6VQW
 | | Type I-F CRISPR-Csy complex with its inhibitor AcrF8 | | Descriptor: | AcrF8, CRISPR-associated endonuclease Cas6/Csy4, CRISPR-associated protein Csy1, ... | | Authors: | Zhang, K, Li, S, Pintilie, G, Zhu, Y, Huang, Z, Chiu, W. | | Deposit date: | 2020-02-06 | | Release date: | 2020-03-11 | | Last modified: | 2024-03-06 | | Method: | ELECTRON MICROSCOPY (3.42 Å) | | Cite: | Inhibition mechanisms of AcrF9, AcrF8, and AcrF6 against type I-F CRISPR-Cas complex revealed by cryo-EM.
Proc.Natl.Acad.Sci.USA, 117, 2020
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6WQH
 | | Molecular basis for the ATPase-powered substrate translocation by the Lon AAA+ protease | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Ig2 substrate, Lon protease, ... | | Authors: | Zhang, K, Li, S, Hsiehb, K, Sub, S, Pintilie, G, Chiu, W, Chang, C. | | Deposit date: | 2020-04-28 | | Release date: | 2021-06-09 | | Last modified: | 2021-11-17 | | Method: | ELECTRON MICROSCOPY (3.6 Å) | | Cite: | Molecular basis for ATPase-powered substrate translocation by the Lon AAA+ protease.
J.Biol.Chem., 297, 2021
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6N3H
 | | Crystal structure of Kelch domain of the human NS1 binding protein | | Descriptor: | Influenza virus NS1A-binding protein | | Authors: | Zhang, K, Shang, G, Padavannil, A, Fontoura, B.M.A, Chook, Y.M. | | Deposit date: | 2018-11-15 | | Release date: | 2018-12-12 | | Last modified: | 2023-10-11 | | Method: | X-RAY DIFFRACTION (2.6 Å) | | Cite: | Structural-functional interactions of NS1-BP protein with the splicing and mRNA export machineries for viral and host gene expression.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
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6N34
 | | Crystal structure of the BTB domain of Human NS1-BP | | Descriptor: | Influenza virus NS1A-binding protein | | Authors: | Zhang, K, Shang, G, Padavannil, A, Fontoura, B, Chook, Y.M. | | Deposit date: | 2018-11-14 | | Release date: | 2018-12-12 | | Last modified: | 2023-10-11 | | Method: | X-RAY DIFFRACTION (2.8 Å) | | Cite: | Structural-functional interactions of NS1-BP protein with the splicing and mRNA export machineries for viral and host gene expression.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
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6NYG
 | | Helicobacter pylori Vacuolating Cytotoxin A Oligomeric Assembly 2a (OA-2a) | | Descriptor: | Vacuolating cytotoxin autotransporter | | Authors: | Zhang, K, Zhang, H, Li, S, Au, S, Chiu, W. | | Deposit date: | 2019-02-11 | | Release date: | 2019-03-27 | | Last modified: | 2019-12-18 | | Method: | ELECTRON MICROSCOPY (3.9 Å) | | Cite: | Cryo-EM structures ofHelicobacter pylorivacuolating cytotoxin A oligomeric assemblies at near-atomic resolution.
Proc. Natl. Acad. Sci. U.S.A., 116, 2019
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6NYM
 | | Helicobacter pylori Vacuolating Cytotoxin A Oligomeric Assembly 2d (OA-2d) | | Descriptor: | Vacuolating cytotoxin autotransporter | | Authors: | Zhang, K, Zhang, H, Li, S, Au, S, Chiu, W. | | Deposit date: | 2019-02-11 | | Release date: | 2019-03-27 | | Last modified: | 2019-12-18 | | Method: | ELECTRON MICROSCOPY (3.6 Å) | | Cite: | Cryo-EM structures ofHelicobacter pylorivacuolating cytotoxin A oligomeric assemblies at near-atomic resolution.
Proc. Natl. Acad. Sci. U.S.A., 116, 2019
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6NYJ
 | | Helicobacter pylori Vacuolating Cytotoxin A Oligomeric Assembly 2b (OA-2b) | | Descriptor: | Vacuolating cytotoxin autotransporter | | Authors: | Zhang, K, Zhang, H, Li, S, Au, S, Chiu, W. | | Deposit date: | 2019-02-11 | | Release date: | 2019-03-27 | | Last modified: | 2019-12-18 | | Method: | ELECTRON MICROSCOPY (3.2 Å) | | Cite: | Cryo-EM structures ofHelicobacter pylorivacuolating cytotoxin A oligomeric assemblies at near-atomic resolution.
Proc. Natl. Acad. Sci. U.S.A., 116, 2019
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6NYL
 | | Helicobacter pylori Vacuolating Cytotoxin A Oligomeric Assembly 2c (OA-2c) | | Descriptor: | Vacuolating cytotoxin autotransporter | | Authors: | Zhang, K, Zhang, H, Li, S, Au, S, Chiu, W. | | Deposit date: | 2019-02-11 | | Release date: | 2019-03-27 | | Last modified: | 2019-12-18 | | Method: | ELECTRON MICROSCOPY (3.7 Å) | | Cite: | Cryo-EM structures ofHelicobacter pylorivacuolating cytotoxin A oligomeric assemblies at near-atomic resolution.
Proc. Natl. Acad. Sci. U.S.A., 116, 2019
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6NYN
 | | Helicobacter pylori Vacuolating Cytotoxin A Oligomeric Assembly 2e (OA-2e) | | Descriptor: | Vacuolating cytotoxin autotransporter | | Authors: | Zhang, K, Zhang, H, Li, S, Au, S, Chiu, W. | | Deposit date: | 2019-02-11 | | Release date: | 2019-03-27 | | Last modified: | 2019-12-18 | | Method: | ELECTRON MICROSCOPY (3.5 Å) | | Cite: | Cryo-EM structures ofHelicobacter pylorivacuolating cytotoxin A oligomeric assemblies at near-atomic resolution.
Proc. Natl. Acad. Sci. U.S.A., 116, 2019
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8QQ3
 | | Streptavidin with a Ni-cofactor | | Descriptor: | 4-[4-[(3~{a}~{S},4~{S},6~{a}~{R})-2-oxidanylidene-1,3,3~{a},4,6,6~{a}-hexahydrothieno[3,4-d]imidazol-4-yl]butylamino]-~{N}1,~{N}1'-di(quinolin-8-yl)cyclohexane-1,1-dicarboxamide, NICKEL (II) ION, Streptavidin | | Authors: | Zhang, K, Jakob, R.P, Ward, T.R. | | Deposit date: | 2023-10-03 | | Release date: | 2024-02-07 | | Last modified: | 2024-02-21 | | Method: | X-RAY DIFFRACTION (1.6 Å) | | Cite: | An artificial nickel chlorinase based on the biotin-streptavidin technology.
Chem.Commun.(Camb.), 60, 2024
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5NVU
 | | Full length human cytoplasmic dynein-1 in the phi-particle conformation | | Descriptor: | Dynein intermediate chain, Dynein light intermediate chain, Dynein motor domain, ... | | Authors: | Zhang, K, Foster, H.E, Carter, A.P. | | Deposit date: | 2017-05-04 | | Release date: | 2017-08-09 | | Last modified: | 2017-09-06 | | Method: | ELECTRON MICROSCOPY (15 Å) | | Cite: | Cryo-EM Reveals How Human Cytoplasmic Dynein Is Auto-inhibited and Activated.
Cell, 169, 2017
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5NVS
 | | Human cytoplasmic dynein-1 tail in the twisted N-terminus state | | Descriptor: | LC8, N-terminal dimerization domain, Robl, ... | | Authors: | Zhang, K, Foster, H.E, Carter, A.P. | | Deposit date: | 2017-05-04 | | Release date: | 2017-06-28 | | Last modified: | 2024-07-10 | | Method: | ELECTRON MICROSCOPY (8.4 Å) | | Cite: | Cryo-EM Reveals How Human Cytoplasmic Dynein Is Auto-inhibited and Activated.
Cell, 169, 2017
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6NYF
 | | Helicobacter pylori Vacuolating Cytotoxin A Oligomeric Assembly 1 (OA-1) | | Descriptor: | Vacuolating cytotoxin autotransporter | | Authors: | Zhang, K, Zhang, H, Li, S, Au, S, Chiu, W. | | Deposit date: | 2019-02-11 | | Release date: | 2019-03-27 | | Last modified: | 2019-12-18 | | Method: | ELECTRON MICROSCOPY (3.2 Å) | | Cite: | Cryo-EM structures ofHelicobacter pylorivacuolating cytotoxin A oligomeric assemblies at near-atomic resolution.
Proc. Natl. Acad. Sci. U.S.A., 116, 2019
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5NUG
 | | Motor domains from human cytoplasmic dynein-1 in the phi-particle conformation | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, Cytoplasmic dynein 1 heavy chain 1, ... | | Authors: | Zhang, K, Foster, H.E, Carter, A.P. | | Deposit date: | 2017-04-30 | | Release date: | 2017-06-28 | | Last modified: | 2024-05-15 | | Method: | ELECTRON MICROSCOPY (3.8 Å) | | Cite: | Cryo-EM Reveals How Human Cytoplasmic Dynein Is Auto-inhibited and Activated.
Cell, 169, 2017
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5NW4
 | | Human cytoplasmic dynein-1 bound to dynactin and an N-terminal construct of BICD2 | | Descriptor: | Arp1, Arp11, BICD2N, ... | | Authors: | Zhang, K, Foster, H.E, Carter, A.P. | | Deposit date: | 2017-05-05 | | Release date: | 2017-08-02 | | Last modified: | 2018-11-21 | | Method: | ELECTRON MICROSCOPY (8.7 Å) | | Cite: | Cryo-EM Reveals How Human Cytoplasmic Dynein Is Auto-inhibited and Activated.
Cell, 169, 2017
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6NUD
 | | Small conformation of ssRNA-bound CRISPR_Csm complex | | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, CRISPR system Cms protein Csm2, CRISPR system single-strand-specific deoxyribonuclease Cas10/Csm1 (subtype III-A), ... | | Authors: | Zhang, K, Pintilie, G, Li, S, Zhu, Y, Chiu, W, Huang, Z. | | Deposit date: | 2019-01-31 | | Release date: | 2019-03-13 | | Last modified: | 2024-03-20 | | Method: | ELECTRON MICROSCOPY (3.5 Å) | | Cite: | Coupling of ssRNA cleavage with DNase activity in type III-A CRISPR-Csm revealed by cryo-EM and biochemistry.
Cell Res., 29, 2019
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6NUE
 | | Small conformation of apo CRISPR_Csm complex | | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, CRISPR system Cms protein Csm2, CRISPR system single-strand-specific deoxyribonuclease Cas10/Csm1 (subtype III-A), ... | | Authors: | Zhang, K, Pintilie, G, Li, S, Zhu, Y, Chiu, W, Huang, Z. | | Deposit date: | 2019-01-31 | | Release date: | 2019-03-13 | | Last modified: | 2024-03-20 | | Method: | ELECTRON MICROSCOPY (3.3 Å) | | Cite: | Coupling of ssRNA cleavage with DNase activity in type III-A CRISPR-Csm revealed by cryo-EM and biochemistry.
Cell Res., 29, 2019
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3ET2
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3ET0
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3ET1
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6UET
 | | SAM-bound SAM-IV riboswitch | | Descriptor: | RNA (119-MER), S-ADENOSYLMETHIONINE | | Authors: | Zhang, K, Li, S, Kappel, K, Pintilie, G, Su, Z, Mou, T, Schmid, M, Das, R, Chiu, W. | | Deposit date: | 2019-09-23 | | Release date: | 2019-12-18 | | Last modified: | 2024-03-20 | | Method: | ELECTRON MICROSCOPY (4.1 Å) | | Cite: | Cryo-EM structure of a 40 kDa SAM-IV riboswitch RNA at 3.7 angstrom resolution.
Nat Commun, 10, 2019
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