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PDB: 891 件

4OV9
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Structure of isopropylmalate synthase binding with alpha-isopropylmalate
分子名称: (2S)-2-hydroxy-2-(propan-2-yl)butanedioic acid, ZINC ION, isopropylmalate synthase
著者Zhang, Z, Wu, J, Wang, C, Zhang, P.
登録日2014-02-20
公開日2014-08-20
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Subdomain II of alpha-isopropylmalate synthase is essential for activity: inferring a mechanism of feedback inhibition.
J.Biol.Chem., 289, 2014
8WSU
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Crystal structure of SFTSV Gc and antibody
分子名称: Ab-H, Ab-L, Glycoprotein C
著者Chang, Z, Gao, F, Wu, Y.
登録日2023-10-17
公開日2024-06-12
実験手法X-RAY DIFFRACTION (3.3 Å)
主引用文献Bispecific antibodies targeting two glycoproteins on SFTSV exhibit synergistic neutralization and protection in a mouse model.
Proc.Natl.Acad.Sci.USA, 121, 2024
8WSN
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Crystal structure of SFTSV Gn and antibody SF1
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Ab1-H, ...
著者Chang, Z, Gao, F, Wu, Y.
登録日2023-10-17
公開日2024-06-12
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Bispecific antibodies targeting two glycoproteins on SFTSV exhibit synergistic neutralization and protection in a mouse model.
Proc.Natl.Acad.Sci.USA, 121, 2024
7OQE
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Saccharomyces cerevisiae spliceosomal pre-A complex (delta BS-A ACT1)
分子名称: 56 kDa U1 small nuclear ribonucleoprotein component, ACT1 pre-mRNA (delta BS-A), Cold sensitive U2 snRNA suppressor 1, ...
著者Zhang, Z, Rigo, N, Dybkov, O, Fourmann, J, Will, C.L, Kumar, V, Urlaub, H, Stark, H, Luehrmann, R.
登録日2021-06-03
公開日2021-08-11
最終更新日2024-07-17
実験手法ELECTRON MICROSCOPY (5.9 Å)
主引用文献Structural insights into how Prp5 proofreads the pre-mRNA branch site.
Nature, 596, 2021
3JAB
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Domain organization and conformational plasticity of the G protein effector, PDE6
分子名称: 3-ISOBUTYL-1-METHYLXANTHINE, GafA domain of cone phosphodiesterase 6C, GafB domain of phosphodiesterase 2A, ...
著者Zhang, Z, He, F, Constantine, R, Baker, M.L, Baehr, W, Schmid, M.F, Wensel, T.G, Agosto, M.A.
登録日2015-05-26
公開日2015-06-10
最終更新日2024-10-16
実験手法ELECTRON MICROSCOPY (11 Å)
主引用文献Domain Organization and Conformational Plasticity of the G Protein Effector, PDE6.
J.Biol.Chem., 290, 2015
3JBQ
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Domain Organization and Conformational Plasticity of the G Protein Effector, PDE6
分子名称: GafA domain of cone phosphodiesterase 6C, GafB domain of phosphodiesterase 2A, IgG1-kappa 2E8 heavy chain, ...
著者Zhang, Z, He, F, Constantine, R, Baker, M.L, Baehr, W, Schmid, M.F, Wensel, T.G, Agosto, M.A.
登録日2015-09-17
公開日2015-09-30
最終更新日2024-10-16
実験手法ELECTRON MICROSCOPY (11 Å)
主引用文献Domain Organization and Conformational Plasticity of the G Protein Effector, PDE6.
J.Biol.Chem., 290, 2015
2BCC
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STIGMATELLIN-BOUND CYTOCHROME BC1 COMPLEX FROM CHICKEN
分子名称: 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine, FE2/S2 (INORGANIC) CLUSTER, PROTOPORPHYRIN IX CONTAINING FE, ...
著者Zhang, Z, Huang, L, Shulmeister, V.M, Chi, Y.I, Kim, K.K, Hung, L.W, Crofts, A.R, Berry, E.A, Kim, S.H.
登録日1998-09-18
公開日1999-08-02
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (3.5 Å)
主引用文献Electron Transfer by Domain Movement in Cytochrome Bc1
Nature, 392, 1998
3RL8
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Crystal structure of hDLG1-PDZ2 complexed with APC
分子名称: 11-mer peptide from Adenomatous polyposis coli protein, Disks large homolog 1
著者Zhang, Z, Li, H, Wu, G.
登録日2011-04-19
公開日2011-12-14
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Molecular basis for the recognition of adenomatous polyposis coli by the Discs Large 1 protein.
Plos One, 6, 2011
4LJY
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Crystal structure of RNA splicing effector Prp5 in complex with ADP
分子名称: (4R)-2-METHYLPENTANE-2,4-DIOL, ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ...
著者Zhang, Z.-M, Li, J, Yang, F, Xu, Y, Zhou, J.
登録日2013-07-05
公開日2013-12-11
最終更新日2019-12-25
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Crystal structure of Prp5p reveals interdomain interactions that impact spliceosome assembly.
Cell Rep, 5, 2013
6BRR
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Crystal structure of DNMT3A (R836A)-DNMT3L in complex with DNA containing two CpG sites
分子名称: DNA (25-MER), DNA (cytosine-5)-methyltransferase 3-like, DNA (cytosine-5)-methyltransferase 3A, ...
著者Zhang, Z.M, Song, J.
登録日2017-11-30
公開日2018-01-31
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.97 Å)
主引用文献Structural basis for DNMT3A-mediated de novo DNA methylation.
Nature, 554, 2018
3VA6
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Crystal Structure of the extracellular domain of the putative hybrid two component system BT4673 from B. thetaiotaomicron
分子名称: Two-component system sensor histidine kinase
著者Zhang, Z, Liu, Q, Hendrickson, W.A.
登録日2011-12-28
公開日2012-06-13
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献The Extraellular Domain Structures of Two Potential Saccharide-sensing Two-component Systems from a Human Gut Symbiont
To be Published
2JX0
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The paxillin-binding domain (PBD) of G Protein Coupled Receptor (GPCR)-kinase (GRK) interacting protein 1 (GIT1)
分子名称: ARF GTPase-activating protein GIT1
著者Zhang, Z, Guibao, C.D, Simmerman, J.A, Zheng, J.
登録日2007-11-01
公開日2008-04-29
最終更新日2024-05-29
実験手法SOLUTION NMR
主引用文献GIT1 paxillin-binding domain is a four-helix bundle, and it binds to both paxillin LD2 and LD4 motifs.
J.Biol.Chem., 283, 2008
4N3Y
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Crystal structure of Rabex-5CC and Rabaptin-5C21 complex
分子名称: Rab GTPase-binding effector protein 1, Rab5 GDP/GTP exchange factor
著者Zhang, Z, Zhang, T, Ding, J.
登録日2013-10-08
公開日2014-07-23
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Molecular mechanism for Rabex-5 GEF activation by Rabaptin-5
Elife, 3, 2014
4Q9U
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Crystal structure of the Rab5, Rabex-5delta and Rabaptin-5C21 complex
分子名称: Rab GTPase-binding effector protein 1, Rab5 GDP/GTP exchange factor, Ras-related protein Rab-5A
著者Zhang, Z, Zhang, T, Ding, J.
登録日2014-05-01
公開日2014-07-23
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (4.618 Å)
主引用文献Molecular mechanism for Rabex-5 GEF activation by Rabaptin-5
Elife, 3, 2014
4LK2
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Crystal structure of RNA splicing effector Prp5
分子名称: NICKEL (II) ION, Pre-mRNA-processing ATP-dependent RNA helicase PRP5
著者Zhang, Z.-M, Li, J, Yang, F, Xu, Y, Zhou, J.
登録日2013-07-05
公開日2013-12-11
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (2.12 Å)
主引用文献Crystal structure of Prp5p reveals interdomain interactions that impact spliceosome assembly.
Cell Rep, 5, 2013
3LWH
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Crystal structure of Cren7-dsDNA complex
分子名称: Chromatin protein Cren7, DNA (5'-D(*GP*TP*AP*AP*TP*TP*AP*C)-3')
著者Zhang, Z.F, Gong, Y, Guo, L, Jiang, T, Huang, L.
登録日2010-02-23
公開日2010-05-26
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structural insights into the interaction of the crenarchaeal chromatin protein Cren7 with DNA
Mol.Microbiol., 76, 2010
5W81
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Phosphorylated, ATP-bound structure of zebrafish cystic fibrosis transmembrane conductance regulator (CFTR)
分子名称: ADENOSINE-5'-TRIPHOSPHATE, Cystic fibrosis transmembrane conductance regulator, MAGNESIUM ION
著者Zhang, Z, Liu, F, Chen, J.
登録日2017-06-21
公開日2017-07-19
最終更新日2024-03-13
実験手法ELECTRON MICROSCOPY (3.37 Å)
主引用文献Conformational Changes of CFTR upon Phosphorylation and ATP Binding.
Cell, 170, 2017
3D8X
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Crystal Structure of Saccharomyces cerevisiae NDPPH Dependent Thioredoxin Reductase 1
分子名称: FLAVIN-ADENINE DINUCLEOTIDE, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, Thioredoxin reductase 1
著者Zhang, Z.Y, Bao, R, Yu, J, Chen, Y.X, Zhou, C.-Z.
登録日2008-05-26
公開日2008-12-09
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Crystal structure of Saccharomyces cerevisiae cytoplasmic thioredoxin reductase Trr1 reveals the structural basis for species-specific recognition of thioredoxin
Biochim.Biophys.Acta, 1794, 2009
2OPW
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Crystal structure of human phytanoyl-CoA dioxygenase PHYHD1 (apo)
分子名称: PHYHD1 protein
著者Zhang, Z, Butler, D, McDonough, M.A, Kavanagh, K.L, Bray, J.E, Ng, S.S, von Delft, F, Arrowsmith, C.H, Weigelt, J, Edwards, A, Sundstrom, M, Schofield, C.J, Oppermann, U, Structural Genomics Consortium (SGC)
登録日2007-01-30
公開日2007-03-06
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Crystal structure of human phytanoyl-CoA dioxygenase PHYHD1 (apo)
To be Published
1M4Z
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Crystal structure of the N-terminal BAH domain of Orc1p
分子名称: MANGANESE (II) ION, ORIGIN RECOGNITION COMPLEX SUBUNIT 1
著者Zhang, Z, Hayashi, M.K, Merkel, O, Stillman, B, Xu, R.-M.
登録日2002-07-05
公開日2002-09-11
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Structure and function of the BAH-containing domain of Orc1p in epigenetic silencing.
EMBO J., 21, 2002
6L4K
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Human serum albumin-Palmitic acid-Cu compound
分子名称: 2-bromanyl-9-ethyl-~{N},~{N},7-trimethyl-3-thia-1$l^{4},5,6$l^{4},10-tetraza-2$l^{4}-cupratricyclo[6.4.0.0^{2,6}]dodeca-1(8),4,6,9,11-pentaen-4-amine, PALMITIC ACID, Serum albumin
著者Zhang, Z.L.
登録日2019-10-17
公開日2020-10-21
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (2.09 Å)
主引用文献Novel Brain-Tumor-Inhibiting Copper(II) Compound Based on a Human Serum Albumin (HSA)-Cell Penetrating Peptide Conjugate.
J.Med.Chem., 62, 2019
3RZ2
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Crystal of Prl-1 complexed with peptide
分子名称: Prl-1 (PTP4A1), Protein tyrosine phosphatase type IVA 1
著者Zhang, Z.-Y, Liu, D, Bai, Y.
登録日2011-05-11
公開日2011-10-26
最終更新日2014-10-29
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献PRL-1 protein promotes ERK1/2 and RhoA protein activation through a non-canonical interaction with the Src homology 3 domain of p115 Rho GTPase-activating protein.
J.Biol.Chem., 286, 2011
1TPB
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OFFSET OF A CATALYTIC LESION BY A BOUND WATER SOLUBLE
分子名称: PHOSPHOGLYCOLOHYDROXAMIC ACID, TRIOSEPHOSPHATE ISOMERASE
著者Zhang, Z, Sugio, S, Komives, E.A, Liu, K.D, Knowles, J.R, Petsko, G.A, Ringe, D.
登録日1994-02-03
公開日1995-02-14
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献The structural basis for pseudoreversion of the E165D lesion by the secondary S96P mutation in triosephosphate isomerase depends on the positions of active site water molecules.
Biochemistry, 34, 1995
1TPU
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S96P CHANGE IS A SECOND-SITE SUPPRESSOR FOR H95N SLUGGISH MUTANT TRIOSEPHOSPHATE ISOMERASE
分子名称: PHOSPHOGLYCOLOHYDROXAMIC ACID, TRIOSEPHOSPHATE ISOMERASE
著者Zhang, Z, Sugio, S, Komives, E.A, Liu, K.D, Stock, A.M, Narayana, N, Xuong, Ng.H, Knowles, J.R, Petsko, G.A, Ringe, D.
登録日1994-11-07
公開日1995-04-20
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献The structural basis for pseudoreversion of the H95N lesion by the secondary S96P mutation in triosephosphate isomerase.
Biochemistry, 35, 1996
1TPH
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1.8 ANGSTROMS CRYSTAL STRUCTURE OF WILD TYPE CHICKEN TRIOSEPHOSPHATE ISOMERASE-PHOSPHOGLYCOLOHYDROXAMATE COMPLEX
分子名称: PHOSPHOGLYCOLOHYDROXAMIC ACID, TRIOSEPHOSPHATE ISOMERASE
著者Zhang, Z, Sugio, S, Komives, E.A, Liu, K.D, Knowles, J.R, Petsko, G.A, Ringe, D.
登録日1993-12-22
公開日1994-04-30
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Crystal structure of recombinant chicken triosephosphate isomerase-phosphoglycolohydroxamate complex at 1.8-A resolution.
Biochemistry, 33, 1994

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