3L6V
 
 | | Crystal Structure of the Xanthomonas campestris Gyrase A C-terminal Domain | | 分子名称: | DNA gyrase subunit A | | 著者 | Hsieh, T.J, Yen, T.J, Lin, T.S, Chang, H.T, Huang, S.Y, Farh, L, Chan, N.L. | | 登録日 | 2009-12-26 | | 公開日 | 2010-03-09 | | 最終更新日 | 2024-05-29 | | 実験手法 | X-RAY DIFFRACTION (2.19 Å) | | 主引用文献 | Twisting of the DNA binding surface by a beta-strand-bearing proline modulates DNA gyrase activity
To be Published
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7E38
 | | Crystal structure of deoxypodophyllotoxin synthase from Sinopodophyllum hexandrum in complex with yatein and succinate | | 分子名称: | (3~{R},4~{R})-4-(1,3-benzodioxol-5-ylmethyl)-3-[(3,4,5-trimethoxyphenyl)methyl]oxolan-2-one, (3~{S},4~{S})-4-(1,3-benzodioxol-5-ylmethyl)-3-[(3,4,5-trimethoxyphenyl)methyl]oxolan-2-one, Deoxypodophyllotoxin synthase, ... | | 著者 | Wu, M.-H, Chang, W.-c, Chien, T.-C, Chan, N.-L. | | 登録日 | 2021-02-08 | | 公開日 | 2021-12-15 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2.05 Å) | | 主引用文献 | Mechanistic analysis of carbon-carbon bond formation by deoxypodophyllotoxin synthase.
Proc.Natl.Acad.Sci.USA, 119, 2022
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7E37
 | | Crystal structure of deoxypodophyllotoxin synthase from Sinopodophyllum hexandrum in complex with 2-oxoglutarate | | 分子名称: | 2-OXOGLUTARIC ACID, Deoxypodophyllotoxin synthase, FE (III) ION | | 著者 | Wu, M.-H, Lin, H.-Y, Chang, W.-c, Chien, T.-C, Chan, N.-L. | | 登録日 | 2021-02-08 | | 公開日 | 2021-12-15 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2.09 Å) | | 主引用文献 | Mechanistic analysis of carbon-carbon bond formation by deoxypodophyllotoxin synthase.
Proc.Natl.Acad.Sci.USA, 119, 2022
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7U4A
 | | Crystal Structure of Zika virus xrRNA1 mutant | | 分子名称: | MAGNESIUM ION, RNA (70-MER) | | 著者 | Thompson, R.D, Carbaugh, D.L, Nielsen, J.R, Witt, C, Meganck, R.M, Rangadurai, A, Zhao, B, Bonin, J.P, Nathan, N.T, Marzluff, W.F, Frank, A.T, Lazear, H.M, Zhang, Q. | | 登録日 | 2022-02-28 | | 公開日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (3.15 Å) | | 主引用文献 | Dynamic Basis of Xrn1 Resistance in Mosquito-borne Flavivirus RNA
To Be Published
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8HJE
 | | Vismodegib binds to the catalytical domain of human Ubiquitin-Specific Protease 28 | | 分子名称: | 2-chloranyl-~{N}-(4-chloranyl-3-pyridin-2-yl-phenyl)-4-methylsulfonyl-benzamide, Ubiquitin carboxyl-terminal hydrolase 28 | | 著者 | Shi, L, Wang, H, Xu, Z, Xiong, B, Zhang, N. | | 登録日 | 2022-11-23 | | 公開日 | 2023-05-03 | | 最終更新日 | 2024-05-29 | | 実験手法 | X-RAY DIFFRACTION (2.85 Å) | | 主引用文献 | Structure-based discovery of potent USP28 inhibitors derived from Vismodegib.
Eur.J.Med.Chem., 254, 2023
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8HT9
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8HSW
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8HT1
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8HSO
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6SES
 | | Tubulin-B2 complex | | 分子名称: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, GLYCEROL, GUANOSINE-5'-DIPHOSPHATE, ... | | 著者 | Guo, B, Rodriguez-Gabin, A, Prota, A.E, Muehlethaler, T, Zhang, N, Ye, K, Steinmetz, M.O, Band Horwitz, S, Smith III, A.B, McDaid, H.M. | | 登録日 | 2019-07-30 | | 公開日 | 2020-07-08 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Structural Refinement of the Tubulin Ligand (+)-Discodermolide to Attenuate Chemotherapy-Mediated Senescence.
Mol.Pharmacol., 98, 2020
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3UUX
 | | Crystal structure of yeast Fis1 in complex with Mdv1 fragment containing N-terminal extension and coiled coil domains | | 分子名称: | Mitochondria fission 1 protein, Mitochondrial division protein 1 | | 著者 | Zhang, Y, Chan, N.C, Gristick, H, Chan, D.C. | | 登録日 | 2011-11-28 | | 公開日 | 2012-02-08 | | 最終更新日 | 2012-04-25 | | 実験手法 | X-RAY DIFFRACTION (3.9 Å) | | 主引用文献 | Crystal structure of mitochondrial fission complex reveals scaffolding function for mitochondrial division 1 (mdv1) coiled coil.
J.Biol.Chem., 287, 2012
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8GXD
 | | L-LEUCINE DEHYDROGENASE FROM EXIGUOBACTERIUM SIBIRICUM | | 分子名称: | CALCIUM ION, GLYCEROL, Glu/Leu/Phe/Val dehydrogenase | | 著者 | Mu, X, Nie, Y, Wu, T, Wang, Y, Zhang, N, Yin, D, Xu, Y. | | 登録日 | 2022-09-19 | | 公開日 | 2023-04-26 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (3.02 Å) | | 主引用文献 | Reshaping Substrate-Binding Pocket of Leucine Dehydrogenase for Bidirectionally Accessing Structurally Diverse Substrates
Acs Catalysis, 13, 2023
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8HSM
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6M7D
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6ILG
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2D27
 | | Structure of the N-terminal domain of XpsE (crystal form I4122) | | 分子名称: | type II secretion ATPase XpsE | | 著者 | Chen, Y, Shiue, S.-J, Huang, C.-W, Chang, J.-L, Chien, Y.-L, Hu, N.-T, Chan, N.-L. | | 登録日 | 2005-09-03 | | 公開日 | 2005-09-20 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (2.21 Å) | | 主引用文献 | Structure and Function of the XpsE N-Terminal Domain, an Essential Component of the Xanthomonas campestris Type II Secretion System
J.Biol.Chem., 280, 2005
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1EET
 | | HIV-1 REVERSE TRANSCRIPTASE IN COMPLEX WITH THE INHIBITOR MSC204 | | 分子名称: | 1-(5-BROMO-PYRIDIN-2-YL)-3-[2-(6-FLUORO-2-HYDROXY-3-PROPIONYL-PHENYL)-CYCLOPROPYL]-UREA, HIV-1 REVERSE TRANSCRIPTASE | | 著者 | Hogberg, M, Sahlberg, C, Engelhardt, P, Noreen, R, Kangasmetsa, J, Johansson, N.G, Oberg, B, Vrang, L, Zhang, H, Sahlberg, B.L, Unge, T, Lovgren, S, Fridborg, K, Backbro, K. | | 登録日 | 2000-02-03 | | 公開日 | 2001-02-07 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (2.73 Å) | | 主引用文献 | Urea-PETT compounds as a new class of HIV-1 reverse transcriptase inhibitors. 3. Synthesis and further structure-activity relationship studies of PETT analogues.
J.Med.Chem., 42, 1999
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2D28
 | | Structure of the N-terminal domain of XpsE (crystal form P43212) | | 分子名称: | CACODYLATE ION, type II secretion ATPase XpsE | | 著者 | Chen, Y, Shiue, S.-J, Huang, C.-W, Chang, J.-L, Chien, Y.-L, Hu, N.-T, Chan, N.-L. | | 登録日 | 2005-09-03 | | 公開日 | 2005-09-20 | | 最終更新日 | 2021-11-10 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Structure and Function of the XpsE N-Terminal Domain, an Essential Component of the Xanthomonas campestris Type II Secretion System
J.Biol.Chem., 280, 2005
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8AH2
 | | Crystal structure of human 14-3-3 zeta fused to the NPM1 peptide including phosphoserine-48 | | 分子名称: | 14-3-3 protein zeta/delta,Nucleophosmin | | 著者 | Boyko, K.M, Kapitonova, A.A, Tugaeva, K.V, Varfolomeeva, L.A, Sluchanko, N.N. | | 登録日 | 2022-07-20 | | 公開日 | 2022-09-14 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | | 主引用文献 | Structural basis for the recognition by 14-3-3 proteins of a conditional binding site within the oligomerization domain of human nucleophosmin.
Biochem.Biophys.Res.Commun., 627, 2022
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5EZK
 | | RNA polymerase model placed by Molecular replacement into X-ray diffraction map of DNA-bound RNA Polymerase-Sigma 54 holoenzyme complex. | | 分子名称: | DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... | | 著者 | Darbari, V.C, Yang, Y, Lu, D, Zhang, N, Glyde, R, Wang, Y, Murakami, K.S, Buck, M, Zhang, X. | | 登録日 | 2015-11-26 | | 公開日 | 2015-12-16 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (8.5 Å) | | 主引用文献 | TRANSCRIPTION. Structures of the RNA polymerase- Sigma 54 reveal new and conserved regulatory strategies.
Science, 349, 2015
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5M9N
 | | Crystal structure of human TDRD1 extended Tudor domain in complex with a symmetrically dimethylated E2F peptide | | 分子名称: | 1,2-ETHANEDIOL, E2F peptide, N3, ... | | 著者 | Tallant, C, Savitsky, P, Moehlenbrink, J, Chan, C, Nunez-Alonso, G, Newman, J.A, von Delft, F, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Fedorov, O, La Thangue, N.B, Knapp, S, Structural Genomics Consortium (SGC) | | 登録日 | 2016-11-01 | | 公開日 | 2016-11-16 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | | 主引用文献 | Crystal structure of human TDRD1 extended Tudor domain in complex with a symmetrically
dimethylated E2F peptide
To Be Published
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5M9O
 | | Crystal structure of human SND1 extended Tudor domain in complex with a symmetrically dimethylated E2F peptide | | 分子名称: | E2F peptide, Staphylococcal nuclease domain-containing protein 1 | | 著者 | Tallant, C, Savitsky, P, Moehlenbrink, J, Chan, C, Nunez-Alonso, G, Siejka, P, Sorrell, F.J, von Delft, F, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Fedorov, O, La Thangue, N.B, Knapp, S, Structural Genomics Consortium (SGC) | | 登録日 | 2016-11-01 | | 公開日 | 2016-12-07 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (1.45 Å) | | 主引用文献 | Crystal structure of human SND1 extended Tudor domain in complex with a symmetrically
dimethylated E2F peptide
To Be Published
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5Y86
 | | Crystal structure of kinase | | 分子名称: | 1,2-ETHANEDIOL, 7-METHOXY-1-METHYL-9H-BETA-CARBOLINE, Dual specificity tyrosine-phosphorylation-regulated kinase 3, ... | | 著者 | Kim, K.L, Cha, J.S, Cho, Y.S, Kim, H.Y, Chang, N.P, Cho, H.S. | | 登録日 | 2017-08-18 | | 公開日 | 2018-05-02 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Crystal Structure of Human Dual-Specificity Tyrosine-Regulated Kinase 3 Reveals New Structural Features and Insights into its Auto-phosphorylation
J. Mol. Biol., 430, 2018
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5NSR
 | | Cryo-EM structure of RNA polymerase-sigma54 holo enzyme with promoter DNA closed complex | | 分子名称: | DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... | | 著者 | Glyde, R, Ye, F.Z, Darbari, V.C, Zhang, N, Buck, M, Zhang, X.D. | | 登録日 | 2017-04-26 | | 公開日 | 2017-06-28 | | 最終更新日 | 2019-12-11 | | 実験手法 | ELECTRON MICROSCOPY (3.8 Å) | | 主引用文献 | Structures of RNA Polymerase Closed and Intermediate Complexes Reveal Mechanisms of DNA Opening and Transcription Initiation.
Mol. Cell, 67, 2017
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8AAQ
 | | Crystal structure of the carotenoid-binding protein domain from silkworm Bombyx mori (BmCBP), CRT-416 form | | 分子名称: | Carotenoid-binding protein | | 著者 | Varfolomeeva, L.A, Slonimskiy, Y.B, Egorkin, N.A, Minyaev, M.E, Faletrov, Y.V, Boyko, K.M, Sluchanko, N.N. | | 登録日 | 2022-07-01 | | 公開日 | 2023-02-01 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Preparation and Structural Studies of the Silkworm Carotenoid-Binding Protein Complexed with a New Pigment
Crystallography Reports, 2022
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