7E37
Crystal structure of deoxypodophyllotoxin synthase from Sinopodophyllum hexandrum in complex with 2-oxoglutarate
Summary for 7E37
| Entry DOI | 10.2210/pdb7e37/pdb |
| Descriptor | Deoxypodophyllotoxin synthase, FE (III) ION, 2-OXOGLUTARIC ACID, ... (4 entities in total) |
| Functional Keywords | non-heme iron/2-oxoglutarate enzyme beta-helix fold deoxypodophyllotoxin biosynthesis carbon-carbon bond formation, biosynthetic protein |
| Biological source | Sinopodophyllum hexandrum (Himalayan may apple) |
| Total number of polymer chains | 2 |
| Total formula weight | 72684.10 |
| Authors | Wu, M.-H.,Lin, H.-Y.,Chang, W.-c.,Chien, T.-C.,Chan, N.-L. (deposition date: 2021-02-08, release date: 2021-12-15, Last modification date: 2023-11-29) |
| Primary citation | Tang, H.,Wu, M.H.,Lin, H.Y.,Han, M.R.,Tu, Y.H.,Yang, Z.J.,Chien, T.C.,Chan, N.L.,Chang, W.C. Mechanistic analysis of carbon-carbon bond formation by deoxypodophyllotoxin synthase. Proc.Natl.Acad.Sci.USA, 119:-, 2022 Cited by PubMed: 34969844DOI: 10.1073/pnas.2113770119 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.09 Å) |
Structure validation
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