3W28
 
 | | The high-resolution crystal structure of TsXylA, intracellular xylanase from /Thermoanaerobacterium saccharolyticum JW/SL-YS485/: the complex of the E251A mutant with xylotriose | | 分子名称: | Glycoside hydrolase family 10, beta-D-xylopyranose-(1-4)-beta-D-xylopyranose-(1-4)-alpha-D-xylopyranose | | 著者 | Han, X, Gao, J, Shang, N, Huang, C.-H, Ko, T.-P, Zhu, Z, Wiegel, J, Shao, W, Guo, R.-T. | | 登録日 | 2012-11-27 | | 公開日 | 2013-04-03 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (1.39 Å) | | 主引用文献 | Structural and functional analyses of catalytic domain of GH10 xylanase from Thermoanaerobacterium saccharolyticum JW/SL-YS485
Proteins, 81, 2013
|
|
4UA1
 | | Crystal structure of dual function transcriptional regulator MerR form Bacillus megaterium MB1 in complex with mercury (II) ion | | 分子名称: | MERCURY (II) ION, Regulatory protein | | 著者 | Chang, C.C, Lin, L.Y, Zou, X.W, Huang, C.C, Chan, N.L. | | 登録日 | 2014-08-07 | | 公開日 | 2015-07-22 | | 最終更新日 | 2024-03-20 | | 実験手法 | X-RAY DIFFRACTION (2.56 Å) | | 主引用文献 | Structural basis of the mercury(II)-mediated conformational switching of the dual-function transcriptional regulator MerR
Nucleic Acids Res., 43, 2015
|
|
6ZFD
 | | 14-3-3 zeta bound to the phosphorylated 18E6 C-terminus | | 分子名称: | 14-3-3 protein zeta/delta,Protein E6, GLYCEROL | | 著者 | Gogl, G, Tugaeva, K.V, Sluchanko, N.N, Trave, G. | | 登録日 | 2020-06-17 | | 公開日 | 2021-02-17 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Hierarchized phosphotarget binding by the seven human 14-3-3 isoforms.
Nat Commun, 12, 2021
|
|
6ZFG
 | | 14-3-3 zeta chimera with 18E6 and fusicoccin | | 分子名称: | 14-3-3 protein zeta/delta,Protein E6, FUSICOCCIN, GLYCEROL | | 著者 | Gogl, G, Tugaeva, K, Sluchanko, N.N, Trave, G. | | 登録日 | 2020-06-17 | | 公開日 | 2021-02-17 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | | 主引用文献 | Hierarchized phosphotarget binding by the seven human 14-3-3 isoforms.
Nat Commun, 12, 2021
|
|
6NUI
 | | Human Guanylate Kinase | | 分子名称: | Guanylate kinase | | 著者 | Sabo, T.M, Khan, N, Ban, D, Trigo-Mourino, P, Carneiro, M.G, Trent, J.O, Konrad, M, Lee, D. | | 登録日 | 2019-02-01 | | 公開日 | 2019-06-26 | | 最終更新日 | 2024-05-01 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Solution structure and functional investigation of human guanylate kinase reveals allosteric networking and a crucial role for the enzyme in cancer.
J.Biol.Chem., 294, 2019
|
|
5EDX
 | | Crystal structure of swine CD8aa homodimer | | 分子名称: | CD8 alpha antigen | | 著者 | Liu, Y.J, Qi, J.X, Zhang, N.Z, Xia, C. | | 登録日 | 2015-10-22 | | 公開日 | 2016-09-14 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (1.801 Å) | | 主引用文献 | The structural basis of chicken, swine and bovine CD8 alpha alpha dimers provides insight into the co-evolution with MHC I in endotherm species.
Sci Rep, 6, 2016
|
|
6TWZ
 | | 14-3-3 sigma complexed with a phosphorylated 16E6 peptide | | 分子名称: | 14-3-3 protein sigma, 2-[3-(2-HYDROXY-1,1-DIHYDROXYMETHYL-ETHYLAMINO)-PROPYLAMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, D(-)-TARTARIC ACID, ... | | 著者 | Gogl, G, Cousido-Siah, A, Sluchanko, N.N, Trave, G. | | 登録日 | 2020-01-13 | | 公開日 | 2020-05-06 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Dual Specificity PDZ- and 14-3-3-Binding Motifs: A Structural and Interactomics Study.
Structure, 28, 2020
|
|
6U76
 | | Structure of methanesulfinate monooxygenase MsuC from Pseudomonas fluorescens. | | 分子名称: | methanesulfinate monooxygenase | | 著者 | Soule, J, Gnann, A.D, Parker, M.J, McKenna, K.C, Nguyen, S.V, Phan, N.T, Wicht, D.K, Dowling, D.P. | | 登録日 | 2019-08-31 | | 公開日 | 2020-11-11 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | To be published
To Be Published
|
|
4GIJ
 | | Crystal Structure of Pseudouridine Monophosphate Glycosidase Complexed with Sulfate | | 分子名称: | MANGANESE (II) ION, Pseudouridine-5'-phosphate glycosidase, SULFATE ION | | 著者 | Huang, S, Mahanta, N, Begley, T.P, Ealick, S.E. | | 登録日 | 2012-08-08 | | 公開日 | 2012-10-31 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (1.941 Å) | | 主引用文献 | Pseudouridine monophosphate glycosidase: a new glycosidase mechanism.
Biochemistry, 51, 2012
|
|
4GIM
 | | Crystal Structure of Pseudouridine Monophosphate Glycosidase Complexed with Pseudouridine 5'-phosphate | | 分子名称: | MANGANESE (II) ION, PSEUDOURIDINE-5'-MONOPHOSPHATE, Pseudouridine-5'-phosphate glycosidase | | 著者 | Huang, S, Mahanta, N, Begley, T.P, Ealick, S.E. | | 登録日 | 2012-08-08 | | 公開日 | 2012-10-31 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (1.802 Å) | | 主引用文献 | Pseudouridine monophosphate glycosidase: a new glycosidase mechanism.
Biochemistry, 51, 2012
|
|
4GIK
 | | Crystal Structure of Pseudouridine Monophosphate Glycosidase/Linear R5P Adduct | | 分子名称: | MANGANESE (II) ION, Pseudouridine-5'-phosphate glycosidase, RIBOSE-5-PHOSPHATE | | 著者 | Huang, S, Mahanta, N, Begley, T.P, Ealick, S.E. | | 登録日 | 2012-08-08 | | 公開日 | 2012-10-31 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (2.187 Å) | | 主引用文献 | Pseudouridine monophosphate glycosidase: a new glycosidase mechanism.
Biochemistry, 51, 2012
|
|
7M5Z
 | | Crystal Structure of the MerTK Kinase Domain in Complex with Inhibitor MIPS15692 | | 分子名称: | 2-(butylamino)-N-[1-(3-fluoropropyl)piperidin-4-yl]-4-{[(1r,4r)-4-hydroxycyclohexyl]amino}pyrimidine-5-carboxamide, Tyrosine-protein kinase Mer | | 著者 | Hermans, S.J, Hancock, N.C, Baell, J.B, Parker, M.W. | | 登録日 | 2021-03-25 | | 公開日 | 2021-10-06 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (3.06 Å) | | 主引用文献 | Development of [ 18 F]MIPS15692, a radiotracer with in vitro proof-of-concept for the imaging of MER tyrosine kinase (MERTK) in neuroinflammatory disease.
Eur.J.Med.Chem., 226, 2021
|
|
1WP5
 | |
6UAL
 | | A Self-Assembling DNA Crystal Scaffold with Cavities Containing 3 Helical Turns per Edge | | 分子名称: | DNA (32-MER), DNA (5'-D(*TP*GP*GP*AP*AP*AP*CP*AP*GP*AP*CP*TP*GP*TP*CP*AP*GP*AP*TP*G)-3'), DNA (5'-D(P*AP*GP*CP*AP*TP*GP*A)-3'), ... | | 著者 | Simmons, C.R, MacCulloch, T, Stephanopoulos, N, Yan, H. | | 登録日 | 2019-09-10 | | 公開日 | 2020-09-16 | | 最終更新日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (4.514 Å) | | 主引用文献 | Crystal Structure of a Self-Assembling DNA Crystal Scaffold with Rhombohedral Symmetry
To Be Published
|
|
3VUZ
 | | Crystal structure of histone methyltransferase SET7/9 in complex with AAM-1 | | 分子名称: | 5'-{[(3S)-3-amino-3-carboxypropyl](hexyl)amino}-5'-deoxyadenosine, Histone-lysine N-methyltransferase SETD7 | | 著者 | Niwa, H, Handa, N, Tomabechi, Y, Honda, K, Toyama, M, Ohsawa, N, Shirouzu, M, Kagechika, H, Hirano, T, Umehara, T, Yokoyama, S. | | 登録日 | 2012-07-10 | | 公開日 | 2013-03-27 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Structures of histone methyltransferase SET7/9 in complexes with adenosylmethionine derivatives
Acta Crystallogr.,Sect.D, 69, 2013
|
|
3VS2
 | | Crystal structure of HCK complexed with a pyrrolo-pyrimidine inhibitor 7-[cis-4-(4-methylpiperazin-1-yl)cyclohexyl]-5-(4-phenoxyphenyl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine | | 分子名称: | 7-[cis-4-(4-methylpiperazin-1-yl)cyclohexyl]-5-(4-phenoxyphenyl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine, CALCIUM ION, CHLORIDE ION, ... | | 著者 | Kuratani, M, Tomabechi, Y, Niwa, H, Parker, J.L, Handa, N, Yokoyama, S. | | 登録日 | 2012-04-21 | | 公開日 | 2013-05-01 | | 最終更新日 | 2023-12-06 | | 実験手法 | X-RAY DIFFRACTION (2.609 Å) | | 主引用文献 | A Pyrrolo-Pyrimidine Derivative Targets Human Primary AML Stem Cells in Vivo
Sci Transl Med, 5, 2013
|
|
3VRZ
 | | Crystal structure of HCK complexed with a pyrrolo-pyrimidine inhibitor 1-[4-(4-amino-7-cyclopentyl-7H-pyrrolo[2,3-d]pyrimidin-5-yl)phenyl]-3-benzylurea | | 分子名称: | 1-[4-(4-amino-7-cyclopentyl-7H-pyrrolo[2,3-d]pyrimidin-5-yl)phenyl]-3-benzylurea, CALCIUM ION, CHLORIDE ION, ... | | 著者 | Kuratani, M, Tomabechi, Y, Handa, N, Yokoyama, S. | | 登録日 | 2012-04-21 | | 公開日 | 2013-05-01 | | 最終更新日 | 2023-12-06 | | 実験手法 | X-RAY DIFFRACTION (2.218 Å) | | 主引用文献 | A Pyrrolo-Pyrimidine Derivative Targets Human Primary AML Stem Cells in Vivo
Sci Transl Med, 5, 2013
|
|
3VRY
 | | Crystal structure of HCK complexed with a pyrrolo-pyrimidine inhibitor 4-Amino-5-(4-phenoxyphenyl)-7H-pyrrolo[2,3-d]pyrimidin-7-yl-cyclopentane | | 分子名称: | 4-Amino-5-(4-phenoxyphenyl)-7H-pyrrolo[2,3-d]pyrimidin-7-yl-cyclopentane, CALCIUM ION, CHLORIDE ION, ... | | 著者 | Kuratani, M, Tomabechi, Y, Niwa, H, Handa, N, Yokoyama, S. | | 登録日 | 2012-04-21 | | 公開日 | 2013-05-01 | | 最終更新日 | 2023-12-06 | | 実験手法 | X-RAY DIFFRACTION (2.481 Å) | | 主引用文献 | A Pyrrolo-Pyrimidine Derivative Targets Human Primary AML Stem Cells in Vivo
Sci Transl Med, 5, 2013
|
|
3VS7
 | | Crystal structure of HCK complexed with a pyrazolo-pyrimidine inhibitor 1-cyclopentyl-3-(1H-pyrrolo[2,3-b]pyridin-5-yl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine | | 分子名称: | 1-cyclopentyl-3-(1H-pyrrolo[2,3-b]pyridin-5-yl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine, CALCIUM ION, CHLORIDE ION, ... | | 著者 | Kuratani, M, Honda, K, Niwa, H, Toyama, M, Handa, N, Yokoyama, S. | | 登録日 | 2012-04-21 | | 公開日 | 2013-05-01 | | 最終更新日 | 2023-12-06 | | 実験手法 | X-RAY DIFFRACTION (3.001 Å) | | 主引用文献 | A Pyrrolo-Pyrimidine Derivative Targets Human Primary AML Stem Cells in Vivo
Sci Transl Med, 5, 2013
|
|
3ML5
 | | Crystal structure of the C183S/C217S mutant of human CA VII in complex with acetazolamide | | 分子名称: | 5-ACETAMIDO-1,3,4-THIADIAZOLE-2-SULFONAMIDE, Carbonic anhydrase 7, ZINC ION | | 著者 | Di Fiore, A, Truppo, E, Supuran, C.T, Alterio, V, Dathan, N, Bootorabi, F, Parkkila, S, Monti, S.M, De Simone, G. | | 登録日 | 2010-04-16 | | 公開日 | 2011-03-02 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (2.05 Å) | | 主引用文献 | Crystal structure of the C183S/C217S mutant of human CA VII in complex with acetazolamide
Bioorg.Med.Chem.Lett., 20, 2010
|
|
2RAL
 | | Crystal Structure Analysis of double cysteine mutant of S.epidermidis adhesin SdrG: Evidence for the Dock,Lock and Latch ligand binding mechanism | | 分子名称: | Serine-aspartate repeat-containing protein G | | 著者 | Ponnuraj, K, Sthanam, N, Bowden, M.G, Hook, M. | | 登録日 | 2007-09-17 | | 公開日 | 2007-11-06 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Evidence for the "dock, lock, and latch" ligand binding mechanism of the staphylococcal microbial surface component recognizing adhesive matrix molecules (MSCRAMM) SdrG.
J.Biol.Chem., 283, 2008
|
|
3VS1
 | | Crystal structure of HCK complexed with a pyrrolo-pyrimidine inhibitor 1-[4-(4-amino-7-cyclopentyl-7H-pyrrolo[2,3-d]pyrimidin-5-yl)phenyl]-3-phenylurea | | 分子名称: | 1-[4-(4-amino-7-cyclopentyl-7H-pyrrolo[2,3-d]pyrimidin-5-yl)phenyl]-3-phenylurea, CALCIUM ION, CHLORIDE ION, ... | | 著者 | Kuratani, M, Tomabechi, Y, Toyama, M, Handa, N, Yokoyama, S. | | 登録日 | 2012-04-21 | | 公開日 | 2013-05-01 | | 最終更新日 | 2023-12-06 | | 実験手法 | X-RAY DIFFRACTION (2.464 Å) | | 主引用文献 | A Pyrrolo-Pyrimidine Derivative Targets Human Primary AML Stem Cells in Vivo
Sci Transl Med, 5, 2013
|
|
3VS4
 | | Crystal structure of HCK complexed with a pyrrolo-pyrimidine inhibitor 5-(4-phenoxyphenyl)-7-(tetrahydro-2H-pyran-4-yl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine | | 分子名称: | 5-(4-phenoxyphenyl)-7-(tetrahydro-2H-pyran-4-yl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine, CALCIUM ION, CHLORIDE ION, ... | | 著者 | Kuratani, M, Tomabechi, Y, Handa, N, Yokoyama, S. | | 登録日 | 2012-04-21 | | 公開日 | 2013-05-01 | | 最終更新日 | 2023-12-06 | | 実験手法 | X-RAY DIFFRACTION (2.747 Å) | | 主引用文献 | A Pyrrolo-Pyrimidine Derivative Targets Human Primary AML Stem Cells in Vivo
Sci Transl Med, 5, 2013
|
|
2G88
 | | MSRECA-dATP COMPLEX | | 分子名称: | 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, CITRIC ACID, MAGNESIUM ION, ... | | 著者 | Krishna, R, Manjunath, G.P, Kumar, P, Surolia, A, Chandra, N.R, Muniyappa, K, Vijayan, M. | | 登録日 | 2006-03-02 | | 公開日 | 2006-05-16 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | | 主引用文献 | Crystallographic identification of an ordered C-terminal domain and a second nucleotide-binding site in RecA: new insights into allostery.
Nucleic Acids Res., 34, 2006
|
|
4W8F
 | | Crystal structure of the dynein motor domain in the AMPPNP-bound state | | 分子名称: | Dynein heavy chain lysozyme chimera, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER | | 著者 | Cheng, H.-C, Bhabha, G, Zhang, N, Vale, R.D. | | 登録日 | 2014-08-24 | | 公開日 | 2014-11-12 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (3.541 Å) | | 主引用文献 | Allosteric communication in the Dynein motor domain.
Cell, 159, 2014
|
|
