7CPO
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![BU of 7cpo by Molmil](/molmil-images/mine/7cpo) | Crystal Structure of Anolis carolinensis MHC I complex | 分子名称: | HIS-VAL-TYR-GLY-PRO-LEU-LYS-PRO-ILE, MHC CLASS I ANTIGEN, beta2-microglobulin | 著者 | Wang, Y, Qu, Z, Ma, L, Wei, X, Zhang, N, Xia, C. | 登録日 | 2020-08-07 | 公開日 | 2021-01-27 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | The Crystal Structure of the MHC Class I (MHC-I) Molecule in the Green Anole Lizard Demonstrates the Unique MHC-I System in Reptiles. J Immunol., 206, 2021
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8AH2
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![BU of 8ah2 by Molmil](/molmil-images/mine/8ah2) | Crystal structure of human 14-3-3 zeta fused to the NPM1 peptide including phosphoserine-48 | 分子名称: | 14-3-3 protein zeta/delta,Nucleophosmin | 著者 | Boyko, K.M, Kapitonova, A.A, Tugaeva, K.V, Varfolomeeva, L.A, Sluchanko, N.N. | 登録日 | 2022-07-20 | 公開日 | 2022-09-14 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | 主引用文献 | Structural basis for the recognition by 14-3-3 proteins of a conditional binding site within the oligomerization domain of human nucleophosmin. Biochem.Biophys.Res.Commun., 627, 2022
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7C1K
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![BU of 7c1k by Molmil](/molmil-images/mine/7c1k) | Crystal structure of the starter condensation domain of rhizomide synthetase RzmA mutant R148A | 分子名称: | Non-ribosomal peptide synthetase modules | 著者 | Zhong, L, Diao, X, Zhang, N, Li, F.W, Zhou, H.B, Chen, H.N, Ren, X, Zhang, Y, Wu, D, Bian, X. | 登録日 | 2020-05-04 | 公開日 | 2020-11-25 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.755 Å) | 主引用文献 | Engineering and elucidation of the lipoinitiation process in nonribosomal peptide biosynthesis. Nat Commun, 12, 2021
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7C1S
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![BU of 7c1s by Molmil](/molmil-images/mine/7c1s) | Crystal structure of the starter condensation domain of rhizomide synthetase RzmA mutant H140A/R148A in complex with C8-CoA and Leu-SNAC | 分子名称: | Non-ribosomal peptide synthetase modules, OCTANOYL-COENZYME A, S-(2-acetamidoethyl) (2S)-2-azanyl-4-methyl-pentanethioate | 著者 | Zhong, L, Diao, X, Zhang, N, Li, F.W, Zhou, H.B, Chen, H.N, Ren, X, Zhang, Y, Wu, D, Bian, X. | 登録日 | 2020-05-05 | 公開日 | 2020-11-25 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.586 Å) | 主引用文献 | Engineering and elucidation of the lipoinitiation process in nonribosomal peptide biosynthesis. Nat Commun, 12, 2021
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3WJA
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![BU of 3wja by Molmil](/molmil-images/mine/3wja) | The crystal structure of human cytosolic NADP(+)-dependent malic enzyme in apo form | 分子名称: | NADP-dependent malic enzyme | 著者 | Li, S.-Y, Chen, M.-C, Yang, P.-C, Chan, N.-L, Liu, J.-H, Hung, H.-C. | 登録日 | 2013-10-08 | 公開日 | 2014-08-13 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2.548 Å) | 主引用文献 | Structural characteristics of the nonallosteric human cytosolic malic enzyme. Biochim.Biophys.Acta, 1844, 2014
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3O15
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![BU of 3o15 by Molmil](/molmil-images/mine/3o15) | Crystal Structure of Bacillus subtilis Thiamin Phosphate Synthase Complexed with a Carboxylated Thiazole Phosphate | 分子名称: | 2-TRIFLUOROMETHYL-5-METHYLENE-5H-PYRIMIDIN-4-YLIDENEAMINE, 4-methyl-5-[2-(phosphonooxy)ethyl]-1,3-thiazole-2-carboxylic acid, PYROPHOSPHATE 2-, ... | 著者 | McCulloch, K.M, Hanes, J.W, Abdelwahed, S, Mahanta, N, Hazra, A, Ishida, K, Begley, T.P, Ealick, S.E. | 登録日 | 2010-07-20 | 公開日 | 2011-07-27 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | 主引用文献 | Crystal Structure and Kinetic Characterization of Bacillus subtilis
Thiamin Phosphate Synthase with a Carboxylated Thiazole Phosphate to be published
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3O16
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![BU of 3o16 by Molmil](/molmil-images/mine/3o16) | Crystal Structure of Bacillus subtilis Thiamin Phosphate Synthase K159A | 分子名称: | Thiamine-phosphate pyrophosphorylase | 著者 | McCulloch, K.M, Hanes, J.W, Abdelwahed, S, Mahanta, N, Hazra, A, Ishida, K, Begley, T.P, Ealick, S.E. | 登録日 | 2010-07-20 | 公開日 | 2011-07-27 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Crystal Structure and Kinetic Characterization of Bacillus subtilis Thiamin
Phosphate Synthase with a Carboxylated Thiazole Phosphate to be published
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1MO6
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![BU of 1mo6 by Molmil](/molmil-images/mine/1mo6) | |
6DEF
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![BU of 6def by Molmil](/molmil-images/mine/6def) | Vps1 GTPase-BSE fusion complexed with GMPPCP | 分子名称: | MAGNESIUM ION, PHOSPHOMETHYLPHOSPHONIC ACID GUANYLATE ESTER, Vps1 GTPase-BSE | 著者 | Ford, M.G.J, Varlakhanova, N.V, Brady, T.M, Chappie, J.S, Hosford, C.J. | 登録日 | 2018-05-11 | 公開日 | 2018-08-22 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (2.26 Å) | 主引用文献 | Structures of the fungal dynamin-related protein Vps1 reveal a unique, open helical architecture. J. Cell Biol., 217, 2018
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1MO3
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6DXK
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![BU of 6dxk by Molmil](/molmil-images/mine/6dxk) | Glucocorticoid Receptor in complex with Compound 11 | 分子名称: | (8S,11R,13S,14S,17S)-11-[4-(dimethylamino)phenyl]-17-(3,3-dimethylbut-1-yn-1-yl)-17-hydroxy-13-methyl-1,2,6,7,8,11,12,13,14,15,16,17-dodecahydro-3H-cyclopenta[a]phenanthren-3-one (non-preferred name), Glucocorticoid receptor | 著者 | Rew, Y, Du, X, Eksterowicz, J, Zhou, H, Jahchan, N, Zhu, L, Yan, X, Kawai, H, McGee, L.R, Medina, J.C, Huang, T, Chen, C, Zavorotinskaya, T, Sutimantanapi, D, Waszczuk, J, Jackson, E, Huang, E, Ye, Q, Fantin, V.R, Daqing, S. | 登録日 | 2018-06-29 | 公開日 | 2018-10-03 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (3.05 Å) | 主引用文献 | Discovery of a Potent and Selective Steroidal Glucocorticoid Receptor Antagonist (ORIC-101). J. Med. Chem., 61, 2018
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7CSQ
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![BU of 7csq by Molmil](/molmil-images/mine/7csq) | Solution structure of the complex between p75NTR-DD and TRADD-DD | 分子名称: | Tumor necrosis factor receptor superfamily member 16, Tumor necrosis factor receptor type 1-associated DEATH domain protein | 著者 | Lin, Z, Zhang, N. | 登録日 | 2020-08-16 | 公開日 | 2021-08-25 | 最終更新日 | 2024-05-15 | 実験手法 | SOLUTION NMR | 主引用文献 | Structural basis of NF-kappa B signaling by the p75 neurotrophin receptor interaction with adaptor protein TRADD through their respective death domains. J.Biol.Chem., 297, 2021
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3PIA
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![BU of 3pia by Molmil](/molmil-images/mine/3pia) | Site-specific Glycosylation of Hemoglobin Utilizing Oxime Ligation Chemistry as a Viable Alternative to PEGylation | 分子名称: | CARBON MONOXIDE, Hemoglobin subunit alpha, Hemoglobin subunit beta, ... | 著者 | Bhatt, V.S, Styslinger, T.J, Zhang, N, Wang, P.G, Palmer, A.F. | 登録日 | 2010-11-05 | 公開日 | 2010-11-24 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 |
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7DMC
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![BU of 7dmc by Molmil](/molmil-images/mine/7dmc) | Dipyridamole binds to the N-terminal domain of human Hsp90A | 分子名称: | 2-[[2-[bis(2-hydroxyethyl)amino]-4,8-di(piperidin-1-yl)pyrimido[5,4-d]pyrimidin-6-yl]-(2-hydroxyethyl)amino]ethanol, CHLORIDE ION, Heat shock protein HSP 90-alpha, ... | 著者 | Shi, L, Zhou, C, Zhong, Y, Gao, J, Zhou, H, Zhang, N. | 登録日 | 2020-12-03 | 公開日 | 2021-12-08 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.34 Å) | 主引用文献 | Dipyridamole interacts with the N-terminal domain of HSP90 and antagonizes the function of the chaperone in multiple cancer cell lines. Biochem Pharmacol, 207, 2022
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3PI9
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![BU of 3pi9 by Molmil](/molmil-images/mine/3pi9) | Site-specific Glycosylation of Hemoglobin Utilizing Oxime Ligation Chemistry as a Viable Alternative to PEGylation | 分子名称: | CARBON MONOXIDE, Hemoglobin subunit alpha, Hemoglobin subunit beta, ... | 著者 | Bhatt, V.S, Styslinger, T.J, Zhang, N, Wang, P.G, Palmer, A.F. | 登録日 | 2010-11-05 | 公開日 | 2010-11-24 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | 主引用文献 |
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6DJA
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![BU of 6dja by Molmil](/molmil-images/mine/6dja) | ZN-DEPENDENT 5/B/6 METALLO-BETA-LACTAMASE FROM BACILLUS CEREUS | 分子名称: | Metallo-beta-lactamase type 2, ZINC ION | 著者 | Bui, A.A, Khan, N.H, Shaw, R.W, Sutton, R.B. | 登録日 | 2018-05-24 | 公開日 | 2019-05-29 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (2.48 Å) | 主引用文献 | A DNA aptamer reveals an allosteric site for inhibition in metallo-beta-lactamases. Plos One, 14, 2019
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1M6I
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![BU of 1m6i by Molmil](/molmil-images/mine/1m6i) | Crystal Structure of Apoptosis Inducing Factor (AIF) | 分子名称: | FLAVIN-ADENINE DINUCLEOTIDE, Programmed cell death protein 8 | 著者 | Ye, H, Cande, C, Stephanou, N.C, Jiang, S, Gurbuxani, S, Larochette, N, Daugas, E, Garrido, C, Kroemer, G, Wu, H. | 登録日 | 2002-07-16 | 公開日 | 2002-08-28 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | DNA binding is required for the apoptogenic action of apoptosis inducing factor. Nat.Struct.Biol., 9, 2002
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4CRI
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![BU of 4cri by Molmil](/molmil-images/mine/4cri) | Crystal Structure of 53BP1 tandem tudor domains in complex with methylated K810 Rb peptide | 分子名称: | RB1 PROTEIN, TUMOR SUPPRESSOR P53-BINDING PROTEIN 1 | 著者 | Krojer, T, Johansson, C, Gileadi, C, Fedorov, O, Carr, S, La Thangue, N.B, Vollmar, M, Crawley, L, von Delft, F, Bountra, C, Arrowsmith, C.H, Edwards, A, Oppermann, U. | 登録日 | 2014-02-26 | 公開日 | 2014-08-06 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (2.35 Å) | 主引用文献 | Lysine Methylation-Dependent Binding of 53BP1 to the Prb Tumor Suppressor. Proc.Natl.Acad.Sci.USA, 111, 2014
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7DME
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![BU of 7dme by Molmil](/molmil-images/mine/7dme) | Solution structure of human Aha1 | 分子名称: | Activator of 90 kDa heat shock protein ATPase homolog 1 | 著者 | Hu, H, Zhou, C, Zhang, N. | 登録日 | 2020-12-03 | 公開日 | 2021-04-21 | 最終更新日 | 2024-05-15 | 実験手法 | SOLUTION NMR | 主引用文献 | Aha1 Exhibits Distinctive Dynamics Behavior and Chaperone-Like Activity. Molecules, 26, 2021
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1PVZ
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![BU of 1pvz by Molmil](/molmil-images/mine/1pvz) | Solution Structure of BmP07, A Novel Potassium Channel Blocker from Scorpion Buthus martensi Karsch, 15 structures | 分子名称: | K+ toxin-like peptide | 著者 | Wu, H, Zhang, N, Wang, Y, Zhang, Q, Ou, L, Li, M, Hu, G. | 登録日 | 2003-06-29 | 公開日 | 2004-05-18 | 最終更新日 | 2018-06-20 | 実験手法 | SOLUTION NMR | 主引用文献 | Solution structure of BmKK2, a new potassium channel blocker from the venom of chinese scorpion Buthus martensi Karsch PROTEINS, 55, 2004
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3PI8
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![BU of 3pi8 by Molmil](/molmil-images/mine/3pi8) | Site-specific Glycosylation of Hemoglobin Utilizing Oxime Ligation Chemistry as a Viable Alternative to PEGylation | 分子名称: | CARBON MONOXIDE, Hemoglobin subunit alpha, Hemoglobin subunit beta, ... | 著者 | Bhatt, V.S, Styslinger, T.J, Zhang, N, Wang, P.G, Palmer, A.F. | 登録日 | 2010-11-05 | 公開日 | 2010-11-24 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 |
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6M05
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![BU of 6m05 by Molmil](/molmil-images/mine/6m05) | Trimolecular G-quadruplex | 分子名称: | DNA (5'-D(*GP*TP*TP*AP*GP*G)-3') | 著者 | Jing, H.T, Fu, W.Q, Zhang, N. | 登録日 | 2020-02-20 | 公開日 | 2021-01-20 | 最終更新日 | 2024-05-15 | 実験手法 | SOLUTION NMR | 主引用文献 | NMR structural study on the self-trimerization of d(GTTAGG) into a dynamic trimolecular G-quadruplex assembly preferentially in Na+ solution with a moderate K+ tolerance. Nucleic Acids Res., 49, 2021
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2MUU
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4ABN
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![BU of 4abn by Molmil](/molmil-images/mine/4abn) | Crystal structure of full length mouse Strap (TTC5) | 分子名称: | 1,2-ETHANEDIOL, TETRATRICOPEPTIDE REPEAT PROTEIN 5 | 著者 | Pike, A.C.W, Bullock, A.N, Kleinekofort, W, Zimmermann, T, Burgess-Brown, N, Sharpe, T.D, Thangaratnarajah, C, Keates, T, Ugochukwu, E, Bunkoczi, G, Uppenberg, J, von Delft, F, Arrowsmith, C.H, Weigelt, J, Edwards, A, Bountra, C, La Thangue, N.B, Knapp, S. | 登録日 | 2011-12-09 | 公開日 | 2012-01-25 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (2.05 Å) | 主引用文献 | The P53 Cofactor Strap Exhibits an Unexpected Tpr Motif and Oligonucleotide-Binding (Ob)-Fold Structure. Proc.Natl.Acad.Sci.USA, 109, 2012
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1VYQ
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![BU of 1vyq by Molmil](/molmil-images/mine/1vyq) | Novel inhibitors of Plasmodium Falciparum dUTPase provide a platform for anti-malarial drug design | 分子名称: | 2,3-DEOXY-3-FLUORO-5-O-TRITYLURIDINE, DEOXYURIDINE 5'-TRIPHOSPHATE NUCLEOTIDOHYDROLASE | 著者 | Whittingham, J.L, Leal, I, Kasinathan, G, Nguyen, C, Bell, E, Jones, A.F, Berry, C, Benito, A, Turkenburg, J.P, Dodson, E.J, Ruiz Perez, L.M, Wilkinson, A.J, Johansson, N.G, Brun, R, Gilbert, I.H, Gonzalez Pacanowska, D, Wilson, K.S. | 登録日 | 2004-05-05 | 公開日 | 2005-05-26 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Dutpase as a Platform for Antimalarial Drug Design: Structural Basis for the Selectivity of a Class of Nucleoside Inhibitors. Structure, 13, 2005
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