5CKS
DAHP (3-deoxy-D-arabinoheptulosonate-7-phosphate) Synthase in complex with DAHP Oxime.
Summary for 5CKS
| Entry DOI | 10.2210/pdb5cks/pdb |
| Descriptor | Phospho-2-dehydro-3-deoxyheptonate aldolase, Phe-sensitive, beta-D-galactopyranose, DAHP Oxime, ... (4 entities in total) |
| Functional Keywords | dahp synthase, inhibitor, complex, transition state mimic, transferase-transferase inhibitor complex, transferase/transferase inhibitor |
| Biological source | Escherichia coli (strain K12) |
| Total number of polymer chains | 4 |
| Total formula weight | 153613.01 |
| Authors | Berti, P.,Junop, M.,Balachandran, N. (deposition date: 2015-07-15, release date: 2016-08-10, Last modification date: 2023-09-27) |
| Primary citation | Balachandran, N.,Heimhalt, M.,Liuni, P.,To, F.,Wilson, D.J.,Junop, M.S.,Berti, P.J. Potent Inhibition of 3-Deoxy-d-arabinoheptulosonate-7-phosphate (DAHP) Synthase by DAHP Oxime, a Phosphate Group Mimic. Biochemistry, 55:6617-6629, 2016 Cited by PubMed: 27933795DOI: 10.1021/acs.biochem.6b00930 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.1181 Å) |
Structure validation
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