5TLQ
 
 | | Model structure of the oxidized PaDsbA1 and 3-[(2-methylbenzyl)sulfanyl]-4H-1,2,4-triazol-4-amine complex | | 分子名称: | 3-[(2-methylbenzyl)sulfanyl]-4H-1,2,4-triazol-4-amine, Thiol:disulfide interchange protein DsbA | | 著者 | Mohanty, B, Rimmer, K.A, McMahon, R.M, Headey, S.J, Vazirani, M, Shouldice, S.R, Coincon, M, Tay, S, Morton, C.J, Simpson, J.S, Martin, J.L, Scanlon, M.S. | | 登録日 | 2016-10-11 | | 公開日 | 2017-04-12 | | 最終更新日 | 2023-06-14 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Fragment library screening identifies hits that bind to the non-catalytic surface of Pseudomonas aeruginosa DsbA1.
PLoS ONE, 12, 2017
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5YTO
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5ZIK
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5ZIX
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1M27
 | | Crystal structure of SAP/FynSH3/SLAM ternary complex | | 分子名称: | CITRATE ANION, Proto-oncogene tyrosine-protein kinase FYN, SH2 domain protein 1A, ... | | 著者 | Chan, B, Griesbach, J, Song, H.K, Poy, F, Terhorst, C, Eck, M.J. | | 登録日 | 2002-06-21 | | 公開日 | 2003-05-06 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | SAP couples Fyn to SLAM immune receptors.
NAT.CELL BIOL., 5, 2003
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4IMA
 | | The structure of C436M-hLPYK in complex with Citrate/Mn/ATP/Fru-1,6-BP | | 分子名称: | 1,2-ETHANEDIOL, 1,6-di-O-phosphono-beta-D-fructofuranose, ADENOSINE, ... | | 著者 | Zhang, B, Holyoak, T, Fenton, A.W, Tang, Q.L, Prasannan, C.B, Deng, J.P. | | 登録日 | 2013-01-02 | | 公開日 | 2013-01-23 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (1.954 Å) | | 主引用文献 | Energetic Coupling between an Oxidizable Cysteine and the Phosphorylatable N-Terminus of Human Liver Pyruvate Kinase.
Biochemistry, 52, 2013
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2YXH
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2YXG
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2YXE
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2ZGI
 | | Crystal Structure of Putative 4-amino-4-deoxychorismate lyase | | 分子名称: | DI(HYDROXYETHYL)ETHER, PYRIDOXAL-5'-PHOSPHATE, Putative 4-amino-4-deoxychorismate lyase, ... | | 著者 | Padmanabhan, B, Bessho, Y, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | | 登録日 | 2008-01-22 | | 公開日 | 2008-07-22 | | 最終更新日 | 2017-10-11 | | 実験手法 | X-RAY DIFFRACTION (1.93 Å) | | 主引用文献 | Structure of putative 4-amino-4-deoxychorismate lyase from Thermus thermophilus HB8.
Acta Crystallogr.,Sect.F, 65, 2009
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2ZAD
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2YXD
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2Z32
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2ZG6
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1X2J
 | | Structural basis for the defects of human lung cancer somatic mutations in the repression activity of Keap1 on Nrf2 | | 分子名称: | Kelch-like ECH-associated protein 1, SULFATE ION | | 著者 | Padmanabhan, B, Tong, K.I, Nakamura, Y, Ohta, T, Scharlock, M, Kobayashi, A, Ohtsuji, M, Kang, M.-I, Yamamoto, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | | 登録日 | 2005-04-25 | | 公開日 | 2006-03-07 | | 最終更新日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | Structural basis for defects of keap1 activity provoked by its point mutations in lung cancer
Mol.Cell, 21, 2006
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1X2R
 | | Structural basis for the defects of human lung cancer somatic mutations in the repression activity of Keap1 on Nrf2 | | 分子名称: | Kelch-like ECH-associated protein 1, Nuclear factor erythroid 2 related factor 2, SULFATE ION | | 著者 | Padmanabhan, B, Tong, K.I, Nakamura, Y, Ohta, T, Scharlock, M, Kobayashi, A, Ohtsuji, M, Kang, M.-I, Yamamoto, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | | 登録日 | 2005-04-26 | | 公開日 | 2006-03-07 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | Structural basis for defects of keap1 activity provoked by its point mutations in lung cancer
Mol.Cell, 21, 2006
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4L1X
 | | Crystal Structuer of Human 3-alpha Hydroxysteroid Dehydrogenase Type 3 V54L Mutant in Complex with NADP+ and Progesterone | | 分子名称: | Aldo-keto reductase family 1 member C2, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, PROGESTERONE, ... | | 著者 | Zhang, B, Hu, X.-J, Lin, S.-X. | | 登録日 | 2013-06-03 | | 公開日 | 2014-04-16 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Human 3-alpha hydroxysteroid dehydrogenase type 3 (3 alpha-HSD3): The V54L mutation restricting the steroid alternative binding and enhancing the 20 alpha-HSD activity
J.Steroid Biochem.Mol.Biol., 141, 2014
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1WG3
 | | Structural analysis of yeast nucleosome-assembly factor CIA1p | | 分子名称: | Anti-silencing protein 1 | | 著者 | Padmanabhan, B, Kataoka, K, Umehara, T, Adachi, N, Yokoyama, S, Horikoshi, M, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | | 登録日 | 2004-05-27 | | 公開日 | 2005-06-14 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (3 Å) | | 主引用文献 | Structural Similarity between Histone Chaperone Cia1p/Asf1p and DNA-Binding Protein NF-{kappa}B
J.Biochem.(Tokyo), 138, 2005
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4L1W
 | | Crystal Structuer of Human 3-alpha Hydroxysteroid Dehydrogenase Type 3 in Complex with NADP+ and Progesterone | | 分子名称: | Aldo-keto reductase family 1 member C2, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, PROGESTERONE, ... | | 著者 | Zhang, B, Hu, X.-J, Lin, S.-X. | | 登録日 | 2013-06-03 | | 公開日 | 2014-04-16 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Human 3-alpha hydroxysteroid dehydrogenase type 3 (3 alpha-HSD3): The V54L mutation restricting the steroid alternative binding and enhancing the 20 alpha-HSD activity
J.Steroid Biochem.Mol.Biol., 141, 2014
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7WIX
 | | Cryo-EM structure of Mycobacterium tuberculosis irtAB in complex with ADP | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, Mycobactin import ATP-binding/permease protein IrtA, ... | | 著者 | Zhang, B, Sun, S, Yang, H, Rao, Z. | | 登録日 | 2022-01-05 | | 公開日 | 2023-01-25 | | 最終更新日 | 2024-04-10 | | 実験手法 | ELECTRON MICROSCOPY (3.53 Å) | | 主引用文献 | Cryo-EM structures for the Mycobacterium tuberculosis iron-loaded siderophore transporter IrtAB.
Protein Cell, 14, 2023
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7WIV
 | | Cryo-EM structure of Mycobacterium tuberculosis irtAB in complex with an AMP-PNP | | 分子名称: | Mycobactin import ATP-binding/permease protein IrtA, Mycobactin import ATP-binding/permease protein IrtB, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER | | 著者 | Zhang, B, Sun, S, Yang, H, Rao, Z. | | 登録日 | 2022-01-05 | | 公開日 | 2023-01-25 | | 最終更新日 | 2024-04-10 | | 実験手法 | ELECTRON MICROSCOPY (2.88 Å) | | 主引用文献 | Cryo-EM structures for the Mycobacterium tuberculosis iron-loaded siderophore transporter IrtAB.
Protein Cell, 14, 2023
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7WIU
 | | Cryo-EM structure of Mycobacterium tuberculosis irtAB in inward-facing state | | 分子名称: | Mycobactin import ATP-binding/permease protein IrtA, Mycobactin import ATP-binding/permease protein IrtB | | 著者 | Zhang, B, Sun, S, Yang, H, Rao, Z. | | 登録日 | 2022-01-05 | | 公開日 | 2023-01-25 | | 最終更新日 | 2024-04-10 | | 実験手法 | ELECTRON MICROSCOPY (3.48 Å) | | 主引用文献 | Cryo-EM structures for the Mycobacterium tuberculosis iron-loaded siderophore transporter IrtAB.
Protein Cell, 14, 2023
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7WIW
 | | Cryo-EM structure of Mycobacterium tuberculosis irtAB complexed with ATP in an occluded conformation | | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, Mycobactin import ATP-binding/permease protein IrtA, ... | | 著者 | Zhang, B, Sun, S, Yang, H, Rao, Z. | | 登録日 | 2022-01-05 | | 公開日 | 2023-01-25 | | 最終更新日 | 2024-04-10 | | 実験手法 | ELECTRON MICROSCOPY (3.12 Å) | | 主引用文献 | Cryo-EM structures for the Mycobacterium tuberculosis iron-loaded siderophore transporter IrtAB.
Protein Cell, 14, 2023
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7VYX
 | | Crystal structure of the selenomethionine(SeMet)-derived Cas12c1 (D969A) ternary complex | | 分子名称: | Non-target DNA strand, Selenomethionine (SeMet)-labeled Cas12c1 D969A mutant, Target DNA strand, ... | | 著者 | Zhang, B, Lin, J.Y, Perculija, V, OuYang, S.Y. | | 登録日 | 2021-11-15 | | 公開日 | 2022-11-02 | | 最終更新日 | 2023-06-14 | | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | | 主引用文献 | Structural insights into target DNA recognition and cleavage by the CRISPR-Cas12c1 system
Nucleic Acids Res., 50, 2022
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7WNX
 | | Cryo-EM structure of Mycobacterium smegmatis MmpL3 complexed with ST004 in lipid nanodiscs | | 分子名称: | N-[2-(2-adamantylamino)ethyl]-1-[2,4-bis(fluoranyl)phenyl]-5-(4-chlorophenyl)-4-methyl-pyrazole-3-carboxamide, Trehalose monomycolate exporter MmpL3 | | 著者 | Zhang, B, Hu, T, Yang, X, Liu, F, Rao, Z. | | 登録日 | 2022-01-20 | | 公開日 | 2022-08-03 | | 最終更新日 | 2024-04-10 | | 実験手法 | ELECTRON MICROSCOPY (3.36 Å) | | 主引用文献 | Structure-based design of anti-mycobacterial drug leads that target the mycolic acid transporter MmpL3.
Structure, 30, 2022
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