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PDB: 1387 results

1AVF
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BU of 1avf by Molmil
ACTIVATION INTERMEDIATE 2 OF HUMAN GASTRICSIN FROM HUMAN STOMACH
Descriptor: GASTRICSIN, SODIUM ION
Authors:Khan, A.R, Cherney, M.M, Tarasova, N.I, James, M.N.G.
Deposit date:1997-09-16
Release date:1998-02-25
Last modified:2024-10-30
Method:X-RAY DIFFRACTION (2.36 Å)
Cite:Structural characterization of activation 'intermediate 2' on the pathway to human gastricsin.
Nat.Struct.Biol., 4, 1997
4PPN
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BU of 4ppn by Molmil
Mycobacterium tuberculosis RecA citrate bound low temperature structure IIA-BN
Descriptor: 1,2-ETHANEDIOL, CITRATE ANION, Protein RecA, ...
Authors:Chandran, A.V, Prabu, J.R, Patil, N.K, Muniyappa, K, Vijayan, M.
Deposit date:2014-02-27
Release date:2015-03-18
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structural studies on Mycobacterium tuberculosis RecA: Molecular plasticity and interspecies variability
J.Biosci., 40, 2015
4PPF
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BU of 4ppf by Molmil
Mycobacterium tuberculosis RecA citrate bound low temperature structure IIA-N
Descriptor: 1,2-ETHANEDIOL, CITRATE ANION, Protein RecA, ...
Authors:Chandran, A.V, Prabu, J.R, Patil, N.K, Muniyappa, K, Vijayan, M.
Deposit date:2014-02-26
Release date:2015-03-18
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structural studies on Mycobacterium tuberculosis RecA: Molecular plasticity and interspecies variability
J.Biosci., 40, 2015
7K6S
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BU of 7k6s by Molmil
Crystal structure of the bromodomain (BD) of human Bromodomain and PHD finger-containing Transcription Factor (BPTF) bound to Compound 4 (SKT1174)
Descriptor: (7-amino-3,4-dihydroquinolin-1(2H)-yl)(cyclopropyl)methanone, 1,2-ETHANEDIOL, CHLORIDE ION, ...
Authors:Chan, A, Schonbrunn, E.
Deposit date:2020-09-21
Release date:2020-12-09
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.23 Å)
Cite:New inhibitors for the BPTF bromodomain enabled by structural biology and biophysical assay development.
Org.Biomol.Chem., 18, 2020
6DCM
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BU of 6dcm by Molmil
The atomic resolution crystal structure of Kringle 2 variant bound with EACA
Descriptor: 6-AMINOHEXANOIC ACID, Plasminogen
Authors:Ghanbarpour, A, Geiger, J.
Deposit date:2018-05-07
Release date:2019-05-15
Last modified:2024-10-16
Method:X-RAY DIFFRACTION (1.031 Å)
Cite:The atomic resolution crystal structure of Kringle 2 variant bound with EACA
To Be Published
4PTL
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BU of 4ptl by Molmil
Mycobacterium tuberculosis RecA glycerol bound low temperature structure IIC-GM
Descriptor: 1,2-ETHANEDIOL, GLYCEROL, Protein RecA, ...
Authors:Chandran, A.V, Prabu, J.R, Patil, N.K, Muniyappa, K, Vijayan, M.
Deposit date:2014-03-11
Release date:2015-03-18
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structural studies on Mycobacterium tuberculosis RecA: Molecular plasticity and interspecies variability
J.Biosci., 40, 2015
7KPR
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BU of 7kpr by Molmil
Structure of wild-type PPM1H phosphatase at 3.1 Angstrom resolution
Descriptor: MAGNESIUM ION, Protein phosphatase 1H
Authors:Khan, A.R, Waschbusch, D.
Deposit date:2020-11-12
Release date:2021-08-04
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (3.09 Å)
Cite:Structural basis for the specificity of PPM1H phosphatase for Rab GTPases.
Embo Rep., 22, 2021
7L4J
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BU of 7l4j by Molmil
Crystal structure of WT PPM1H phosphatase
Descriptor: MAGNESIUM ION, Protein phosphatase 1H
Authors:Khan, A.R, Waschbusch, D.
Deposit date:2020-12-19
Release date:2021-08-04
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.451 Å)
Cite:Structural basis for the specificity of PPM1H phosphatase for Rab GTPases.
Embo Rep., 22, 2021
7L4I
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BU of 7l4i by Molmil
Crystal structure of a substrate-trapping variant of PPM1H phosphatase
Descriptor: MAGNESIUM ION, Protein phosphatase 1H
Authors:Khan, A.R, Waschbusch, D.
Deposit date:2020-12-19
Release date:2021-08-04
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.58 Å)
Cite:Structural basis for the specificity of PPM1H phosphatase for Rab GTPases.
Embo Rep., 22, 2021
8V9R
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BU of 8v9r by Molmil
Cryo-EM Structure of a Proteolytic ClpXP AAA+ Machine Poised to Unfold a Branched-Degron DHFR-ssrA Substrate Bound with MTX
Descriptor: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ATP-dependent Clp protease ATP-binding subunit ClpX, ...
Authors:Ghanbarpour, A, Sauer, R.T, Davis, J.H.
Deposit date:2023-12-09
Release date:2024-10-16
Method:ELECTRON MICROSCOPY (2.8 Å)
Cite:Cryo-EM structure of a fully-engaged DHFR-ssrA substrate and the AAA+ ClpXP protease
To Be Published
4PO9
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BU of 4po9 by Molmil
Mycobacterium tuberculosis RecA glycerol bound low temperature structure IIC-BR
Descriptor: 1,2-ETHANEDIOL, GLYCEROL, Protein RecA, ...
Authors:Chandran, A.V, Prabu, J.R, Patil, N.K, Muniyappa, K, Vijayan, M.
Deposit date:2014-02-25
Release date:2015-03-18
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.75 Å)
Cite:Structural studies on Mycobacterium tuberculosis RecA: Molecular plasticity and interspecies variability
J.Biosci., 40, 2015
4PSV
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BU of 4psv by Molmil
Mycobacterium tuberculosis RecA phosphate bound room temperature structure I-RT
Descriptor: PHOSPHATE ION, Protein RecA, 1st part, ...
Authors:Chandran, A.V, Prabu, J.R, Patil, N.K, Muniyappa, K, Vijayan, M.
Deposit date:2014-03-08
Release date:2015-03-18
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structural studies on Mycobacterium tuberculosis RecA: Molecular plasticity and interspecies variability
J.Biosci., 40, 2015
4PO1
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BU of 4po1 by Molmil
Mycobacterium tuberculosis RecA glycerol bound room temperature structure IIC-RT
Descriptor: GLYCEROL, Protein RecA
Authors:Chandran, A.V, Prabu, J.R, Patil, N.K, Muniyappa, K, Vijayan, M.
Deposit date:2014-02-23
Release date:2015-03-18
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (3.4 Å)
Cite:Structural studies on Mycobacterium tuberculosis RecA: Molecular plasticity and interspecies variability
J.Biosci., 40, 2015
4POA
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BU of 4poa by Molmil
Mycobacterium tuberculosis RecA glycerol bound low temperature structure IIC-BN
Descriptor: 1,2-ETHANEDIOL, GLYCEROL, Protein RecA, ...
Authors:Chandran, A.V, Prabu, J.R, Patil, N.K, Muniyappa, K, Vijayan, M.
Deposit date:2014-02-25
Release date:2015-03-18
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.95 Å)
Cite:Structural studies on Mycobacterium tuberculosis RecA: Molecular plasticity and interspecies variability
J.Biosci., 40, 2015
2O3M
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BU of 2o3m by Molmil
Monomeric G-DNA tetraplex from human C-kit promoter
Descriptor: 5'-D(*AP*GP*GP*GP*AP*GP*GP*GP*CP*GP*CP*TP*GP*GP*GP*AP*GP*GP*AP*GP*GP*G)-3'
Authors:Phan, A.T, Kuryavyi, V.V, Burge, S, Neidle, S, Patel, D.J.
Deposit date:2006-12-01
Release date:2007-05-22
Last modified:2023-12-27
Method:SOLUTION NMR
Cite:Structure of an unprecedented G-quadruplex scaffold in the human c-kit promoter.
J.Am.Chem.Soc., 129, 2007
8TEK
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BU of 8tek by Molmil
Baseplate of Nexin-dynein regulatory complex from Tetrahymena thermophila
Descriptor: CFAP20, Cilia- and flagella-associated protein 91, Coiled-coil protein, ...
Authors:Ghanaeian, A.G, Black, C.S, Yang, S.K, Bui, K.H.
Deposit date:2023-07-06
Release date:2023-09-20
Last modified:2023-09-27
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:Integrated modeling of the Nexin-dynein regulatory complex reveals its regulatory mechanism.
Nat Commun, 14, 2023
8TH8
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BU of 8th8 by Molmil
Linker domain of Nexin-dynein regulatory complex from Tetrahymena thermophila
Descriptor: AAA family ATPase CDC48 subfamily protein, Calmodulin 7-2, Coiled-coil domain-containing protein 153, ...
Authors:Ghanaeian, A.G, Bui, K.H.
Deposit date:2023-07-14
Release date:2023-09-20
Last modified:2024-10-23
Method:ELECTRON MICROSCOPY (7.4 Å)
Cite:Integrated modeling of the Nexin-dynein regulatory complex reveals its regulatory mechanism.
Nat Commun, 14, 2023
8TID
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BU of 8tid by Molmil
Combined linker domain of N-DRC and associated proteins Tetrahymena
Descriptor: AAA family ATPase CDC48 subfamily protein, CFAP20, Calmodulin 7-2, ...
Authors:Ghanaeian, A.G, Majhi, S.M, McCaffrey, C.M, Nami, B.N, Black, C.B, Yang, S.K, Legal, T.L, Papoulas, O.P, Janowska, M.J, Valente-Paterno, M.V, Marcotte, E.M, Wloga, D.W, Bui, K.H.
Deposit date:2023-07-19
Release date:2023-09-27
Last modified:2024-04-03
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:Integrated modeling of the Nexin-dynein regulatory complex reveals its regulatory mechanism.
Nat Commun, 14, 2023
6HH2
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BU of 6hh2 by Molmil
Rab29 small GTPase bound to GDP
Descriptor: GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, Ras-related protein Rab-7L1
Authors:Khan, A.R, McGrath, E, Waschbusch, D.
Deposit date:2018-08-24
Release date:2019-09-11
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (1.449 Å)
Cite:LRRK2 binds to the Rab32 subfamily in a GTP-dependent mannerviaits armadillo domain.
Small GTPases, 2019
4JMQ
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BU of 4jmq by Molmil
Crystal structure of pb9: The Dit of bacteriophage T5.
Descriptor: Bacteriophage T5 distal tail protein
Authors:Flayhan, A, Vellieux, F.M.D, Girard, E, Maury, O, Boulanger, P, Breyton, C.
Deposit date:2013-03-14
Release date:2013-11-06
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (1.895 Å)
Cite:Crystal Structure of pb9, the Distal Tail Protein of Bacteriophage T5: a Conserved Structural Motif among All Siphophages.
J.Virol., 88, 2014
7K6R
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BU of 7k6r by Molmil
Crystal structure of the bromodomain (BD) of human Bromodomain and PHD finger-containing Transcription Factor (BPTF) bound to GSK4027
Descriptor: 1,2-ETHANEDIOL, 4-bromo-2-methyl-5-[[(3~{R},5~{R})-1-methyl-5-phenyl-piperidin-3-yl]amino]pyridazin-3-one, Nucleosome-remodeling factor subunit BPTF
Authors:Chan, A, Schonbrunn, E.
Deposit date:2020-09-21
Release date:2020-12-09
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:New inhibitors for the BPTF bromodomain enabled by structural biology and biophysical assay development.
Org.Biomol.Chem., 18, 2020
7KDZ
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BU of 7kdz by Molmil
Crystal structure of the bromodomain (BD) of human Bromodomain and PHD finger-containing Transcription Factor (BPTF) bound to TP-238
Descriptor: 1,2-ETHANEDIOL, 6-{4-[3-(dimethylamino)propoxy]phenyl}-2-(methylsulfonyl)-N-[3-(1H-pyrazol-1-yl)propyl]pyrimidin-4-amine, Nucleosome-remodeling factor subunit BPTF
Authors:Chan, A, Schonbrunn, E.
Deposit date:2020-10-09
Release date:2020-12-09
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.54 Å)
Cite:New inhibitors for the BPTF bromodomain enabled by structural biology and biophysical assay development
Organic & Biomolecular Chemistry, 18(27), 2020
7L73
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BU of 7l73 by Molmil
Crystal structure of the first bromodomain (BD1) of human BRDT bound to ERK5-IN-1
Descriptor: 11-cyclopentyl-2-({2-ethoxy-4-[4-(4-methylpiperazin-1-yl)piperidine-1-carbonyl]phenyl}amino)-5-methyl-5,11-dihydro-6H-pyrimido[4,5-b][1,4]benzodiazepin-6-one, Bromodomain testis-specific protein
Authors:Chan, A, Karim, M.R, Schonbrunn, E.
Deposit date:2020-12-25
Release date:2021-06-30
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.46 Å)
Cite:Differential BET Bromodomain Inhibition by Dihydropteridinone and Pyrimidodiazepinone Kinase Inhibitors.
J.Med.Chem., 64, 2021
7LEJ
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BU of 7lej by Molmil
Crystal structure of the second bromodomain (BD2) of human BRDT bound to Volasertib
Descriptor: Bromodomain testis-specific protein, N-{trans-4-[4-(cyclopropylmethyl)piperazin-1-yl]cyclohexyl}-4-{[(7R)-7-ethyl-5-methyl-8-(1-methylethyl)-6-oxo-5,6,7,8-tetrahydropteridin-2-yl]amino}-3-methoxybenzamide
Authors:Chan, A, Karim, M.R, Schonbrunn, E.
Deposit date:2021-01-14
Release date:2021-07-14
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.73 Å)
Cite:Differential BET Bromodomain Inhibition by Dihydropteridinone and Pyrimidodiazepinone Kinase Inhibitors.
J.Med.Chem., 64, 2021
7LEL
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BU of 7lel by Molmil
Crystal structure of the second bromodomain (BD2) of human BRDT bound to Bromosporine
Descriptor: Bromodomain testis-specific protein, Bromosporine
Authors:Chan, A, Karim, M.R, Schonbrunn, E.
Deposit date:2021-01-14
Release date:2021-07-14
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:Differential BET Bromodomain Inhibition by Dihydropteridinone and Pyrimidodiazepinone Kinase Inhibitors.
J.Med.Chem., 64, 2021

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