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PDB: 183 件
9B91
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BU of 9b91 by Molmil
Cryo-EM structure of the human TRPM4 channel subunit in complex with calcium and ATP at 37 degrees Celsius
分子名称: ADENOSINE-5'-TRIPHOSPHATE, CALCIUM ION, Transient receptor potential cation channel subfamily M member 4
著者Hu, J, Lu, W, Du, J.
登録日2024-04-01
公開日2024-05-15
最終更新日2024-06-26
実験手法ELECTRON MICROSCOPY (3.3 Å)
主引用文献Physiological temperature drives TRPM4 ligand recognition and gating.
Nature, 630, 2024
9B93
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BU of 9b93 by Molmil
Cryo-EM structure of the human TRPM4 channel in the presence of EDTA at 37 degrees Celsius
分子名称: Transient receptor potential cation channel subfamily M member 4
著者Hu, J, Lu, W, Du, J.
登録日2024-04-01
公開日2024-05-15
最終更新日2024-06-26
実験手法ELECTRON MICROSCOPY (3.1 Å)
主引用文献Physiological temperature drives TRPM4 ligand recognition and gating.
Nature, 630, 2024
9B8Z
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BU of 9b8z by Molmil
Cryo-EM structure of the human TRPM4 channel subunit in complex with calcium and decavanadate at 37 degrees Celsius
分子名称: CALCIUM ION, DECAVANADATE, Transient receptor potential cation channel subfamily M member 4
著者Hu, J, Lu, W, Du, J.
登録日2024-04-01
公開日2024-05-15
最終更新日2024-06-26
実験手法ELECTRON MICROSCOPY (3.4 Å)
主引用文献Physiological temperature drives TRPM4 ligand recognition and gating.
Nature, 630, 2024
9B92
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BU of 9b92 by Molmil
Cryo-EM structure of the human TRPM4 in complex with calcium at 18 degrees Celsius
分子名称: CALCIUM ION, Transient receptor potential cation channel subfamily M member 4
著者Hu, J, Lu, W, Du, J.
登録日2024-04-01
公開日2024-05-15
最終更新日2024-06-26
実験手法ELECTRON MICROSCOPY (3.5 Å)
主引用文献Physiological temperature drives TRPM4 ligand recognition and gating.
Nature, 630, 2024
9B8X
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BU of 9b8x by Molmil
Cryo-EM structure of the human TRPM4 channel subunit in complex with calcium 37 degrees Celsius
分子名称: CALCIUM ION, Transient receptor potential cation channel subfamily M member 4
著者Hu, J, Lu, W, Du, J.
登録日2024-04-01
公開日2024-05-15
最終更新日2024-06-26
実験手法ELECTRON MICROSCOPY (3 Å)
主引用文献Physiological temperature drives TRPM4 ligand recognition and gating.
Nature, 630, 2024
2QLD
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BU of 2qld by Molmil
human Hsp40 Hdj1
分子名称: DnaJ homolog subfamily B member 1
著者Hu, J, Wu, Y, Li, J, Fu, Z, Sha, B.
登録日2007-07-12
公開日2008-07-15
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献The crystal structure of the putative peptide-binding fragment from the human Hsp40 protein Hdj1.
Bmc Struct.Biol., 8, 2008
2HDX
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BU of 2hdx by Molmil
Crystal structure of the Src homology-2 domain of SH2-B in complex with Jak2 pTyr813 phosphopeptide
分子名称: Jak2 protein, SH2-B PH domain containing signaling mediator 1 gamma isoform
著者Hu, J, Hubbard, S.R.
登録日2006-06-21
公開日2006-08-08
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.35 Å)
主引用文献Structural Basis for Phosphotyrosine Recognition by the Src Homology-2 Domains of the Adapter Proteins SH2-B and APS.
J.Mol.Biol., 361, 2006
2H95
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BU of 2h95 by Molmil
Structure of the Amantadine-Blocked Influenza A M2 Proton Channel Trans-membrane Domain by Solid-state NMR spectroscopy
分子名称: Matrix protein 2
著者Hu, J, Asbury, T, Cross, T.A.
登録日2006-06-08
公開日2007-04-24
最終更新日2024-05-29
実験手法SOLID-STATE NMR
主引用文献Backbone structure of the amantadine-blocked trans-membrane domain m2 proton channel from influenza a virus.
Biophys.J., 92, 2007
5TEQ
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BU of 5teq by Molmil
C20S C293G MUTANT N-TERMINAL HUMAN ATP CITRATE LYASE BOUND TO CITRATE
分子名称: ATP-citrate synthase, CITRATE ANION, PHOSPHATE ION, ...
著者Hu, J, Fraser, M.E.
登録日2016-09-22
公開日2017-08-09
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Binding of hydroxycitrate to human ATP-citrate lyase.
Acta Crystallogr D Struct Biol, 73, 2017
5TDF
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BU of 5tdf by Molmil
TEV Cleaved Human ATP Citrate Lyase Bound to 4S hydroxycitrate
分子名称: 3-C-carboxy-2-deoxy-D-erythro-pentaric acid, ADENINE, ADENOSINE-5'-DIPHOSPHATE, ...
著者Hu, J, Fraser, M.E.
登録日2016-09-19
公開日2017-08-09
最終更新日2017-08-16
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Binding of hydroxycitrate to human ATP-citrate lyase.
Acta Crystallogr D Struct Biol, 73, 2017
5TE1
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BU of 5te1 by Molmil
C20S, C293G Mutant N-terminal Human ATP Citrate Lyase Bound to 4R-Hydroxycitrate
分子名称: 3-C-carboxy-2-deoxy-L-threo-pentaric acid, ATP-citrate synthase, PHOSPHATE ION, ...
著者Hu, J, Fraser, M.E.
登録日2016-09-20
公開日2017-08-09
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (2.25 Å)
主引用文献Binding of hydroxycitrate to human ATP-citrate lyase.
Acta Crystallogr D Struct Biol, 73, 2017
5TDM
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BU of 5tdm by Molmil
TEV Cleaved Human ATP Citrate Lyase Bound to 4R-Hydroxycitrate and ADP
分子名称: 3-C-carboxy-2-deoxy-L-threo-pentaric acid, ADENOSINE, ADENOSINE-5'-DIPHOSPHATE, ...
著者Hu, J, Fraser, M.E.
登録日2016-09-19
公開日2017-08-09
最終更新日2017-08-16
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Binding of hydroxycitrate to human ATP-citrate lyase.
Acta Crystallogr D Struct Biol, 73, 2017
5TDZ
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BU of 5tdz by Molmil
TEV Cleaved Human ATP Citrate Lyase Bound to Tartrate and ADP
分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ADENOSINE, ADENOSINE-5'-DIPHOSPHATE, ...
著者Hu, J, Fraser, M.E.
登録日2016-09-20
公開日2017-08-09
最終更新日2017-08-16
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Binding of hydroxycitrate to human ATP-citrate lyase.
Acta Crystallogr D Struct Biol, 73, 2017
2HDV
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BU of 2hdv by Molmil
Crystal structure of the Src Homology-2 domain of the adapter protein SH2-B
分子名称: SH2-B PH domain containing signaling mediator 1 gamma isoform
著者Hu, J, Hubbard, S.R.
登録日2006-06-20
公開日2006-08-08
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structural Basis for Phosphotyrosine Recognition by the Src Homology-2 Domains of the Adapter Proteins SH2-B and APS.
J.Mol.Biol., 361, 2006
5TDE
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BU of 5tde by Molmil
TEV Cleaved Human ATP Citrate Lyase Bound to Citrate
分子名称: ATP-citrate synthase, CITRATE ANION, DIHYDROGENPHOSPHATE ION, ...
著者Hu, J, Fraser, M.E.
登録日2016-09-19
公開日2017-08-09
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Binding of hydroxycitrate to human ATP-citrate lyase.
Acta Crystallogr D Struct Biol, 73, 2017
3S0X
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BU of 3s0x by Molmil
The crystal structure of GxGD membrane protease FlaK
分子名称: Peptidase A24B, FlaK domain protein
著者Hu, J, Xue, Y, Ha, Y.
登録日2011-05-13
公開日2011-08-03
実験手法X-RAY DIFFRACTION (3.6 Å)
主引用文献The crystal structure of GXGD membrane protease FlaK.
Nature, 475, 2011
7X4B
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BU of 7x4b by Molmil
Crystal Structure of An Anti-CRISPR Protein
分子名称: Anti-CRISPR protein (AcrIIC1), SULFATE ION
著者Hu, J, Zhang, S, Gao, J.Y, Liu, X, Liu, J.
登録日2022-03-02
公開日2022-10-26
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.61 Å)
主引用文献A redox switch regulates the assembly and anti-CRISPR activity of AcrIIC1.
Nat Commun, 13, 2022
5TET
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BU of 5tet by Molmil
TEV Cleaved Human ATP Citrate Lyase Bound to 4S Hydroxycitrate
分子名称: 3-C-carboxy-2-deoxy-D-erythro-pentaric acid, ATP-citrate synthase, GLYCEROL, ...
著者Hu, J, Fraser, M.E.
登録日2016-09-22
公開日2017-08-09
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Binding of hydroxycitrate to human ATP-citrate lyase.
Acta Crystallogr D Struct Biol, 73, 2017
5TES
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BU of 5tes by Molmil
TEV Cleaved Human ATP Citrate Lyase Bound to Citrate and ADP
分子名称: ADENOSINE-5'-DIPHOSPHATE, ATP-citrate synthase, CITRATE ANION, ...
著者Hu, J, Fraser, M.E.
登録日2016-09-22
公開日2017-08-09
最終更新日2017-08-16
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Binding of hydroxycitrate to human ATP-citrate lyase.
Acta Crystallogr D Struct Biol, 73, 2017
5YDU
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BU of 5ydu by Molmil
Crystal structure of Utp30
分子名称: PHOSPHATE ION, Ribosome biogenesis protein UTP30
著者Hu, J, Zhu, X, Ye, K.
登録日2017-09-14
公開日2017-11-01
最終更新日2024-03-27
実験手法X-RAY DIFFRACTION (2.646 Å)
主引用文献Structure and RNA recognition of ribosome assembly factor Utp30.
RNA, 23, 2017
7CQZ
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BU of 7cqz by Molmil
crystal structure of mouse FAM46C (TENT5C)
分子名称: CHLORIDE ION, GLYCEROL, Terminal nucleotidyltransferase 5C
著者Hu, J.L, Zhang, H, Gao, S.
登録日2020-08-12
公開日2021-06-09
最終更新日2024-03-27
実験手法X-RAY DIFFRACTION (2.34969759 Å)
主引用文献Structural and functional characterization of multiple myeloma associated cytoplasmic poly(A) polymerase FAM46C.
Cancer Commun (Lond), 41, 2021
1VSQ
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BU of 1vsq by Molmil
Solution NMR structure of the productive complex between IIAMannose and IIBMannose of the mannose transporter of the E. coli phosphotransferase system
分子名称: Mannose-specific phosphotransferase enzyme IIA component, Mannose-specific phosphotransferase enzyme IIB component
著者Clore, G.M, Hu, J, Hu, K.
登録日2008-01-10
公開日2008-02-19
最終更新日2023-12-27
実験手法SOLUTION NMR
主引用文献Solution NMR Structures of Productive and Non-productive Complexes between the A and B Domains of the Cytoplasmic Subunit of the Mannose Transporter of the Escherichia coli Phosphotransferase System.
J.Biol.Chem., 283, 2008
4FO9
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BU of 4fo9 by Molmil
Crystal structure of the E3 SUMO Ligase PIAS2
分子名称: E3 SUMO-protein ligase PIAS2, UNKNOWN ATOM OR ION, ZINC ION
著者Dong, A, Hu, J, Dobrovetsky, E, Tempel, W, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Tong, Y, Structural Genomics Consortium (SGC)
登録日2012-06-20
公開日2012-07-18
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.39 Å)
主引用文献Crystal structure of the E3 SUMO Ligase PIAS2
to be published
5VKB
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BU of 5vkb by Molmil
Ethylene forming enzyme in complex with manganese, 2-oxoglutarate and argininamide
分子名称: 2-OXOGLUTARIC ACID, 2-oxoglutarate-dependent ethylene/succinate-forming enzyme, ARGININEAMIDE, ...
著者Fellner, M, Martinez, S, Hu, J, Hausinger, R.P.
登録日2017-04-21
公開日2017-08-16
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (1.139 Å)
主引用文献Structures and Mechanisms of the Non-Heme Fe(II)- and 2-Oxoglutarate-Dependent Ethylene-Forming Enzyme: Substrate Binding Creates a Twist.
J. Am. Chem. Soc., 139, 2017
6D6Z
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BU of 6d6z by Molmil
Structure of the malate racemase apoprotein from Thermoanaerobacterium thermosaccharolyticum
分子名称: Malate racemase Mar2
著者Fellner, M, Hausinger, R.P, Hu, J.
登録日2018-04-23
公開日2019-04-24
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.38 Å)
主引用文献Uncovering a superfamily of nickel-dependent hydroxyacid racemases and epimerases.
Sci Rep, 10, 2020

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件を2024-07-10に公開中

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