6LJT
 
 | | Crystal structure of human FABP4 in complex with a novel inhibitor | | Descriptor: | 1,2-ETHANEDIOL, 2-[(3-chloranyl-2-phenyl-phenyl)amino]benzoic acid, Fatty acid-binding protein, ... | | Authors: | Su, H.X, Zhang, X.L, Li, M.J, Xu, Y.C. | | Deposit date: | 2019-12-17 | | Release date: | 2020-04-15 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (1.45 Å) | | Cite: | Exploration of Fragment Binding Poses Leading to Efficient Discovery of Highly Potent and Orally Effective Inhibitors of FABP4 for Anti-inflammation.
J.Med.Chem., 63, 2020
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7FAU
 | | Structure Determination of the NB1B11-RBD Complex | | Descriptor: | NB_1B11, Spike protein S1, ZINC ION | | Authors: | Shi, Z.Z, Li, X.X, Wang, L, Sun, Z.C, Zhang, H.W, Chen, X.C, Cui, Q.Q, Qiao, H.R, Lan, Z.Y, Zhang, X. | | Deposit date: | 2021-07-07 | | Release date: | 2022-06-01 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (2.08 Å) | | Cite: | Structural basis of nanobodies neutralizing SARS-CoV-2 variants.
Structure, 30, 2022
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1FZX
 | | NMR SOLUTION STRUCTURE OF THE DNA DODECAMER GGCAAAAAACGG | | Descriptor: | 5'-D(*CP*CP*GP*TP*TP*TP*TP*TP*TP*GP*CP*C)-3', 5'-D(*GP*GP*CP*AP*AP*AP*AP*AP*AP*CP*GP*G)-3' | | Authors: | MacDonald, D, Herbert, K, Zhang, X, Pologruto, T, Lu, P. | | Deposit date: | 2000-10-04 | | Release date: | 2001-03-14 | | Last modified: | 2024-05-22 | | Method: | SOLUTION NMR | | Cite: | Solution structure of an A-tract DNA bend.
J.Mol.Biol., 306, 2001
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6LJW
 | | Crystal structure of human FABP4 in complex with a novel inhibitor | | Descriptor: | 1,2-ETHANEDIOL, 2-phenylazanylbenzoic acid, Fatty acid-binding protein, ... | | Authors: | Su, H.X, Zhang, X.L, Li, M.J, Xu, Y.C. | | Deposit date: | 2019-12-17 | | Release date: | 2020-04-15 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (1.4 Å) | | Cite: | Exploration of Fragment Binding Poses Leading to Efficient Discovery of Highly Potent and Orally Effective Inhibitors of FABP4 for Anti-inflammation.
J.Med.Chem., 63, 2020
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4GYV
 | | Crystal structure of the DH domain of FARP2 | | Descriptor: | FERM, RhoGEF and pleckstrin domain-containing protein 2 | | Authors: | He, X, Zhang, X. | | Deposit date: | 2012-09-05 | | Release date: | 2013-03-13 | | Last modified: | 2017-11-15 | | Method: | X-RAY DIFFRACTION (2.9 Å) | | Cite: | Structural Basis for Autoinhibition of the Guanine Nucleotide Exchange Factor FARP2.
Structure, 21, 2013
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2W5Q
 | | Structure-based mechanism of lipoteichoic acid synthesis by Staphylococcus aureus LtaS. | | Descriptor: | 1,2-ETHANEDIOL, MANGANESE (II) ION, PROCESSED GLYCEROL PHOSPHATE LIPOTEICHOIC ACID SYNTHASE | | Authors: | Lu, D, Wormann, M.E, Zhang, X, Scheewind, O, Grundling, A, Freemont, P.S. | | Deposit date: | 2008-12-11 | | Release date: | 2009-02-03 | | Last modified: | 2024-05-08 | | Method: | X-RAY DIFFRACTION (1.2 Å) | | Cite: | Structure-Based Mechanism of Lipoteichoic Acid Synthesis by Staphylococcus Aureus Ltas.
Proc.Natl.Acad.Sci.USA, 106, 2009
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6CG0
 | | Cryo-EM structure of mouse RAG1/2 HFC complex (3.17 A) | | Descriptor: | CALCIUM ION, DNA (30-MER), DNA (41-MER), ... | | Authors: | Chen, X, Kim, M, Chuenchor, W, Cui, Y, Zhang, X, Zhou, Z.H, Gellert, M, Yang, W. | | Deposit date: | 2018-02-19 | | Release date: | 2018-04-25 | | Last modified: | 2024-03-13 | | Method: | ELECTRON MICROSCOPY (3.17 Å) | | Cite: | Cracking the DNA Code for V(D)J Recombination.
Mol. Cell, 70, 2018
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4EVV
 | | mouse MBD4 glycosylase domain in complex with a G:T mismatch | | Descriptor: | 1,2-ETHANEDIOL, DNA (5'-D(*CP*CP*AP*TP*GP*TP*GP*CP*TP*GP*A)-3'), DNA (5'-D(*TP*CP*AP*GP*CP*GP*CP*AP*TP*GP*G)-3'), ... | | Authors: | Hashimoto, H, Zhang, X, Cheng, X. | | Deposit date: | 2012-04-26 | | Release date: | 2012-07-11 | | Last modified: | 2023-09-13 | | Method: | X-RAY DIFFRACTION (2.39 Å) | | Cite: | Excision of thymine and 5-hydroxymethyluracil by the MBD4 DNA glycosylase domain: structural basis and implications for active DNA demethylation.
Nucleic Acids Res., 40, 2012
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6K5G
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6D2Q
 | | Crystal structure of the FERM domain of zebrafish FARP1 | | Descriptor: | FERM, RhoGEF (ARHGEF) and pleckstrin domain protein 1 (chondrocyte-derived) | | Authors: | Kuo, Y.C, Zhang, X. | | Deposit date: | 2018-04-13 | | Release date: | 2018-07-18 | | Last modified: | 2023-10-04 | | Method: | X-RAY DIFFRACTION (2.99 Å) | | Cite: | Structural analyses of FERM domain-mediated membrane localization of FARP1.
Sci Rep, 8, 2018
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6K8P
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4GZN
 | | Mouse ZFP57 zinc fingers in complex with methylated DNA | | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, ACETATE ION, CALCIUM ION, ... | | Authors: | Liu, Y, Zhang, X, Cheng, X. | | Deposit date: | 2012-09-06 | | Release date: | 2012-10-17 | | Last modified: | 2024-02-28 | | Method: | X-RAY DIFFRACTION (0.99 Å) | | Cite: | An atomic model of Zfp57 recognition of CpG methylation within a specific DNA sequence.
Genes Dev., 26, 2012
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4GZU
 | | Crystal structure of the DH-PH-PH domain of FARP2 | | Descriptor: | FERM, RhoGEF and pleckstrin domain-containing protein 2 | | Authors: | He, X, Zhang, X. | | Deposit date: | 2012-09-06 | | Release date: | 2013-03-13 | | Last modified: | 2023-09-13 | | Method: | X-RAY DIFFRACTION (3.2 Å) | | Cite: | Structural Basis for Autoinhibition of the Guanine Nucleotide Exchange Factor FARP2.
Structure, 21, 2013
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4F5X
 | | Location of the dsRNA-dependent polymerase, VP1, in rotavirus particles | | Descriptor: | Intermediate capsid protein VP6, RNA-directed RNA polymerase, VP2 protein, ... | | Authors: | Estrozi, L.F, Settembre, E.C, Goret, G, McClain, B, Zhang, X, Chen, J.Z, Grigorieff, N, Harrison, S.C. | | Deposit date: | 2012-05-13 | | Release date: | 2012-10-24 | | Last modified: | 2023-09-13 | | Method: | X-RAY DIFFRACTION (5 Å) | | Cite: | Location of the dsRNA-Dependent Polymerase, VP1, in Rotavirus Particles.
J.Mol.Biol., 425, 2013
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2VII
 | | PspF1-275-Mg-AMP | | Descriptor: | ADENOSINE MONOPHOSPHATE, MAGNESIUM ION, PSP OPERON TRANSCRIPTIONAL ACTIVATOR | | Authors: | Joly, N, Rappas, M, Buck, M, Zhang, X. | | Deposit date: | 2007-12-04 | | Release date: | 2008-01-22 | | Last modified: | 2023-12-13 | | Method: | X-RAY DIFFRACTION (2.85 Å) | | Cite: | Trapping of a Transcription Complex Using a New Nucleotide Analogue: AMP Aluminium Fluoride
J.Mol.Biol., 375, 2008
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3MUS
 | | 2A Resolution Structure of Rat Type B Cytochrome b5 | | Descriptor: | Cytochrome b5 type B, PROTOPORPHYRIN IX CONTAINING FE | | Authors: | Terzyan, S, Zhang, X, Benson, D.R. | | Deposit date: | 2010-05-03 | | Release date: | 2011-04-13 | | Last modified: | 2023-09-06 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Accommodating a Non-Conservative Internal Mutation by Water-Mediated Hydrogen-Bonding Between beta-Sheet Strands: A Comparison of Human and Rat Type B (Mitochondrial) Cytochrome b5
Biochemistry, 50, 2011
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1P9E
 | | Crystal Structure Analysis of Methyl Parathion Hydrolase from Pseudomonas sp WBC-3 | | Descriptor: | CADMIUM ION, Methyl Parathion Hydrolase, POTASSIUM ION, ... | | Authors: | Dong, Y, Sun, L, Bartlam, M, Rao, Z, Zhang, X. | | Deposit date: | 2003-05-11 | | Release date: | 2004-05-25 | | Last modified: | 2024-03-13 | | Method: | X-RAY DIFFRACTION (2.4 Å) | | Cite: | Crystal Structure Analysis of Methyl Parathion Hydrolase from Pseudomonas sp WBC-3
To be Published
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1F6W
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1F4H
 | | E. COLI (LACZ) BETA-GALACTOSIDASE (ORTHORHOMBIC) | | Descriptor: | BETA-GALACTOSIDASE, MAGNESIUM ION | | Authors: | Juers, D.H, Jacobson, R.H, Wigley, D, Zhang, X.J, Huber, R.E, Tronrud, D.E, Matthews, B.W. | | Deposit date: | 2000-06-07 | | Release date: | 2001-02-21 | | Last modified: | 2024-02-07 | | Method: | X-RAY DIFFRACTION (2.8 Å) | | Cite: | High resolution refinement of beta-galactosidase in a new crystal form reveals multiple metal-binding sites and provides a structural basis for alpha-complementation.
Protein Sci., 9, 2000
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1F4A
 | | E. COLI (LACZ) BETA-GALACTOSIDASE (NCS CONSTRAINED MONOMER-ORTHORHOMBIC) | | Descriptor: | BETA-GALACTOSIDASE, MAGNESIUM ION | | Authors: | Juers, D.H, Jacobson, R.H, Wigley, D, Zhang, X.J, Huber, R.E, Tronrud, D.E, Matthews, B.W. | | Deposit date: | 2000-06-07 | | Release date: | 2001-02-21 | | Last modified: | 2024-02-07 | | Method: | X-RAY DIFFRACTION (2.8 Å) | | Cite: | High resolution refinement of beta-galactosidase in a new crystal form reveals multiple metal-binding sites and provides a structural basis for alpha-complementation.
Protein Sci., 9, 2000
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4H6Y
 | | Crystal structure of the DH-PH-PH domain of FARP1 | | Descriptor: | FERM, RhoGEF and pleckstrin domain-containing protein 1 | | Authors: | He, X, Zhang, X. | | Deposit date: | 2012-09-19 | | Release date: | 2013-03-13 | | Last modified: | 2024-02-28 | | Method: | X-RAY DIFFRACTION (4.09 Å) | | Cite: | Structural Basis for Autoinhibition of the Guanine Nucleotide Exchange Factor FARP2.
Structure, 21, 2013
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3AIY
 | | R6 HUMAN INSULIN HEXAMER (SYMMETRIC), NMR, REFINED AVERAGE STRUCTURE | | Descriptor: | PHENOL, PROTEIN (INSULIN) | | Authors: | O'Donoghue, S.I, Chang, X, Abseher, R, Nilges, M, Led, J.J. | | Deposit date: | 1998-12-29 | | Release date: | 2000-02-28 | | Last modified: | 2023-12-27 | | Method: | SOLUTION NMR | | Cite: | Unraveling the symmetry ambiguity in a hexamer: calculation of the R6 human insulin structure.
J.Biomol.NMR, 16, 2000
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1F9V
 | | CRYSTAL STRUCTURES OF MUTANTS REVEAL A SIGNALLING PATHWAY FOR ACTIVATION OF THE KINESIN MOTOR ATPASE | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, KINESIN-LIKE PROTEIN KAR3, MAGNESIUM ION | | Authors: | Yun, M, Zhang, X, Park, C.G, Park, H.W, Endow, S.A. | | Deposit date: | 2000-07-11 | | Release date: | 2001-06-13 | | Last modified: | 2024-02-07 | | Method: | X-RAY DIFFRACTION (1.3 Å) | | Cite: | A structural pathway for activation of the kinesin motor ATPase.
EMBO J., 20, 2001
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2UXU
 | | TtgR in complex with Naringenin | | Descriptor: | HTH-TYPE TRANSCRIPTIONAL REGULATOR TTGR, NARINGENIN | | Authors: | Alguel, Y, Meng, C, Teran, W, Krell, T, Ramos, J.L, Gallegos, M.-T, Zhang, X. | | Deposit date: | 2007-03-29 | | Release date: | 2007-05-08 | | Last modified: | 2024-05-08 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | Crystal Structures of Multidrug Binding Protein Ttgr in Complex with Antibiotics and Plant Antimicrobials.
J.Mol.Biol., 369, 2007
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2UXO
 | | TtgR in complex with Tetracycline | | Descriptor: | HTH-TYPE TRANSCRIPTIONAL REGULATOR TTGR, TETRACYCLINE | | Authors: | Alguel, Y, Meng, C, Teran, W, Krell, T, Ramos, J.L, Gallegos, M.-T, Zhang, X. | | Deposit date: | 2007-03-28 | | Release date: | 2007-05-08 | | Last modified: | 2024-05-08 | | Method: | X-RAY DIFFRACTION (2.7 Å) | | Cite: | Crystal Structures of Multidrug Binding Protein Ttgr in Complex with Antibiotics and Plant Antimicrobials.
J.Mol.Biol., 369, 2007
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