3KV5
 
 | | Structure of KIAA1718, human Jumonji demethylase, in complex with N-oxalylglycine | | Descriptor: | FE (II) ION, JmjC domain-containing histone demethylation protein 1D, N-OXALYLGLYCINE, ... | | Authors: | Horton, J.R, Upadhyay, A.K, Qi, H.H, Zhang, X, Shi, Y, Cheng, X. | | Deposit date: | 2009-11-29 | | Release date: | 2009-12-22 | | Last modified: | 2023-09-06 | | Method: | X-RAY DIFFRACTION (2.39 Å) | | Cite: | Enzymatic and structural insights for substrate specificity of a family of jumonji histone lysine demethylases.
Nat.Struct.Mol.Biol., 17, 2010
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5ZZ8
 | | Structure of the Herpes simplex virus type 2 C-capsid with capsid-vertex-specific component | | Descriptor: | Major capsid protein, UL17, UL25, ... | | Authors: | Wang, J.L, Yuan, S, Zhu, D.J, Tang, H, Wang, N, Chen, W.Y, Gao, Q, Li, Y.H, Wang, J.Z, Liu, H.R, Zhang, X.Z, Rao, Z.H, Wang, X.X. | | Deposit date: | 2018-05-31 | | Release date: | 2018-10-10 | | Last modified: | 2019-11-06 | | Method: | ELECTRON MICROSCOPY (3.75 Å) | | Cite: | Structure of the herpes simplex virus type 2 C-capsid with capsid-vertex-specific component.
Nat Commun, 9, 2018
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1I42
 | | NMR STRUCTURE OF THE UBX DOMAIN FROM P47 | | Descriptor: | P47 | | Authors: | Yuan, X, Shaw, A, Zhang, X, Kondo, H, Lally, J, Freemont, P.S, Matthews, S. | | Deposit date: | 2001-02-19 | | Release date: | 2001-08-29 | | Last modified: | 2024-05-29 | | Method: | SOLUTION NMR | | Cite: | Solution structure and interaction surface of the C-terminal domain from p47: a major p97-cofactor involved in SNARE disassembly.
J.Mol.Biol., 311, 2001
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5WWL
 | | Crystal structure of the Schizogenesis pombe kinetochore Mis12C subcomplex | | Descriptor: | Centromere protein mis12, Kinetochore protein nnf1 | | Authors: | Wang, C, Zhou, X, Wu, M, Zhang, X, Zang, J. | | Deposit date: | 2017-01-02 | | Release date: | 2017-11-15 | | Last modified: | 2024-03-20 | | Method: | X-RAY DIFFRACTION (2.4 Å) | | Cite: | Phosphorylation of CENP-C by Aurora B facilitates kinetochore attachment error correction in mitosis.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
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7LLL
 | | Exendin-4-bound Glucagon-Like Peptide-1 (GLP-1) Receptor in complex with Gs protein | | Descriptor: | Exendin-4, Glucagon-like peptide 1 receptor, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... | | Authors: | Wootten, D, Sexton, P.M, Belousoff, M.J, Danev, R, Zhang, X, Khoshouei, M, Venugopal, H. | | Deposit date: | 2021-02-04 | | Release date: | 2022-01-12 | | Last modified: | 2022-01-26 | | Method: | ELECTRON MICROSCOPY (3.7 Å) | | Cite: | Dynamics of GLP-1R peptide agonist engagement are correlated with kinetics of G protein activation.
Nat Commun, 13, 2022
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7LLY
 | | Oxyntomodulin-bound Glucagon-Like Peptide-1 (GLP-1) Receptor in complex with Gs protein | | Descriptor: | Glucagon-like peptide 1 receptor, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... | | Authors: | Wootten, D, Sexton, P.M, Belousoff, M.J, Danev, R, Zhang, X, Khoshouei, M, Venugopal, H. | | Deposit date: | 2021-02-04 | | Release date: | 2022-01-12 | | Last modified: | 2022-01-26 | | Method: | ELECTRON MICROSCOPY (3.3 Å) | | Cite: | Dynamics of GLP-1R peptide agonist engagement are correlated with kinetics of G protein activation.
Nat Commun, 13, 2022
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5FB1
 | | Crystal Structure of a PHD finger bound to histone H3 K9me3 peptide | | Descriptor: | MALONATE ION, Nuclear autoantigen Sp-100, Peptide from Histone H3, ... | | Authors: | Li, H, Zhang, X. | | Deposit date: | 2015-12-13 | | Release date: | 2016-05-04 | | Last modified: | 2024-03-20 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | Multifaceted Histone H3 Methylation and Phosphorylation Readout by the Plant Homeodomain Finger of Human Nuclear Antigen Sp100C
J.Biol.Chem., 291, 2016
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3KV9
 | | Structure of KIAA1718 Jumonji domain | | Descriptor: | FE (II) ION, JmjC domain-containing histone demethylation protein 1D, OXYGEN MOLECULE | | Authors: | Horton, J.R, Upadhyay, A.K, Qi, H.H, Zhang, X, Shi, Y, Cheng, X. | | Deposit date: | 2009-11-29 | | Release date: | 2009-12-22 | | Last modified: | 2023-09-06 | | Method: | X-RAY DIFFRACTION (2.29 Å) | | Cite: | Enzymatic and structural insights for substrate specificity of a family of jumonji histone lysine demethylases.
Nat.Struct.Mol.Biol., 17, 2010
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3KVA
 | | Structure of KIAA1718 Jumonji domain in complex with alpha-ketoglutarate | | Descriptor: | 2-OXOGLUTARIC ACID, FE (II) ION, JmjC domain-containing histone demethylation protein 1D, ... | | Authors: | Horton, J.R, Upadhyay, A.K, Qi, H.H, Zhang, X, Shi, Y, Cheng, X. | | Deposit date: | 2009-11-29 | | Release date: | 2009-12-22 | | Last modified: | 2023-09-06 | | Method: | X-RAY DIFFRACTION (2.79 Å) | | Cite: | Enzymatic and structural insights for substrate specificity of a family of jumonji histone lysine demethylases.
Nat.Struct.Mol.Biol., 17, 2010
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3KV6
 | | Structure of KIAA1718, human Jumonji demethylase, in complex with alpha-ketoglutarate | | Descriptor: | 2-OXOGLUTARIC ACID, FE (II) ION, JmjC domain-containing histone demethylation protein 1D, ... | | Authors: | Horton, J.R, Upadhyay, A.K, Qi, H.H, Zhang, X, Shi, Y, Cheng, X. | | Deposit date: | 2009-11-29 | | Release date: | 2009-12-22 | | Last modified: | 2023-09-06 | | Method: | X-RAY DIFFRACTION (2.89 Å) | | Cite: | Enzymatic and structural insights for substrate specificity of a family of jumonji histone lysine demethylases.
Nat.Struct.Mol.Biol., 17, 2010
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3L64
 | | T4 Lysozyme S44E/WT* | | Descriptor: | BETA-MERCAPTOETHANOL, Lysozyme | | Authors: | Blaber, M, Zhang, X.-J, Lindstrom, J.D, Pepiot, S.D, Baase, W.A, Matthews, B.W. | | Deposit date: | 2009-12-23 | | Release date: | 2010-01-19 | | Last modified: | 2024-02-21 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | Determination of alpha-helix propensity within the context of a folded protein. Sites 44 and 131 in bacteriophage T4 lysozyme.
J.Mol.Biol., 235, 1994
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1DP0
 | | E. COLI BETA-GALACTOSIDASE AT 1.7 ANGSTROM | | Descriptor: | BETA-GALACTOSIDASE, DIMETHYL SULFOXIDE, MAGNESIUM ION, ... | | Authors: | Juers, D.H, Jacobson, R.H, Wigley, D, Zhang, X.J, Huber, R.E, Tronrud, D.E, Matthews, B.W. | | Deposit date: | 1999-12-22 | | Release date: | 2001-02-21 | | Last modified: | 2024-02-07 | | Method: | X-RAY DIFFRACTION (1.7 Å) | | Cite: | High resolution refinement of beta-galactosidase in a new crystal form reveals multiple metal-binding sites and provides a structural basis for alpha-complementation.
Protein Sci., 9, 2000
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6HTS
 | | Cryo-EM structure of the human INO80 complex bound to nucleosome | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Actin-related protein 5, Chromatin-remodeling ATPase INO80, ... | | Authors: | Ayala, R, Willhoft, O, Aramayo, R.J, Wilkinson, M, McCormack, E.A, Ocloo, L, Wigley, D.B, Zhang, X. | | Deposit date: | 2018-10-04 | | Release date: | 2018-11-07 | | Last modified: | 2024-05-15 | | Method: | ELECTRON MICROSCOPY (4.8 Å) | | Cite: | Structure and regulation of the human INO80-nucleosome complex.
Nature, 556, 2018
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8JEL
 | | Crystal structure of TIGIT in complexed with Ociperlimab, crystal form I | | Descriptor: | T-cell immunoreceptor with Ig and ITIM domains, antibody heavy chain, antibody light chain | | Authors: | Sun, J, Zhang, X.X, Song, J. | | Deposit date: | 2023-05-16 | | Release date: | 2024-02-28 | | Last modified: | 2024-05-22 | | Method: | X-RAY DIFFRACTION (2.45 Å) | | Cite: | Structural insights into the unique pH-responsive characteristics of the anti-TIGIT therapeutic antibody Ociperlimab.
Structure, 32, 2024
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8JEQ
 | | Crystal structure of Tiragolumab | | Descriptor: | antibody heavy chain, antibody light chain | | Authors: | Sun, J, Zhang, X.X, Song, J. | | Deposit date: | 2023-05-16 | | Release date: | 2024-02-28 | | Last modified: | 2024-05-22 | | Method: | X-RAY DIFFRACTION (1.96 Å) | | Cite: | Structural insights into the unique pH-responsive characteristics of the anti-TIGIT therapeutic antibody Ociperlimab.
Structure, 32, 2024
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8JEP
 | | Crystal structure of Ociperlimab | | Descriptor: | antibody heavy chain, antibody light chain | | Authors: | Sun, J, Zhang, X.X, Song, J. | | Deposit date: | 2023-05-16 | | Release date: | 2024-02-28 | | Last modified: | 2024-05-22 | | Method: | X-RAY DIFFRACTION (1.7 Å) | | Cite: | Structural insights into the unique pH-responsive characteristics of the anti-TIGIT therapeutic antibody Ociperlimab.
Structure, 32, 2024
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8JEN
 | | Crystal structure of TIGIT in complexed with Ociperlimab, crystal form II | | Descriptor: | T-cell immunoreceptor with Ig and ITIM domains, antibody heavy chain, antibody light chain | | Authors: | Sun, J, Zhang, X.X, Song, J. | | Deposit date: | 2023-05-16 | | Release date: | 2024-02-28 | | Last modified: | 2024-05-22 | | Method: | X-RAY DIFFRACTION (2.71 Å) | | Cite: | Structural insights into the unique pH-responsive characteristics of the anti-TIGIT therapeutic antibody Ociperlimab.
Structure, 32, 2024
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8JEO
 | | Crystal structure of TIGIT in complexed with Tiragolumab | | Descriptor: | T-cell immunoreceptor with Ig and ITIM domains, antibody heavy chain, antibody light chain | | Authors: | Sun, J, Zhang, X.X, Song, J. | | Deposit date: | 2023-05-16 | | Release date: | 2024-02-28 | | Last modified: | 2024-05-22 | | Method: | X-RAY DIFFRACTION (2.06 Å) | | Cite: | Structural insights into the unique pH-responsive characteristics of the anti-TIGIT therapeutic antibody Ociperlimab.
Structure, 32, 2024
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6A96
 | | Cryo-EM structure of the human alpha5beta3 GABAA receptor in complex with GABA and Nb25 | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, GAMMA-AMINO-BUTANOIC ACID, Gamma-aminobutyric acid receptor subunit alpha-5,Gamma-aminobutyric acid receptor subunit alpha-5, ... | | Authors: | Liu, S, Xu, L, Guan, F, Liu, Y.T, Cui, Y, Zhang, Q, Bi, G.Q, Zhou, Z.H, Zhang, X, Ye, S. | | Deposit date: | 2018-07-11 | | Release date: | 2018-10-03 | | Last modified: | 2023-11-15 | | Method: | ELECTRON MICROSCOPY (3.51 Å) | | Cite: | Cryo-EM structure of the human alpha 5 beta 3 GABAAreceptor.
Cell Res., 28, 2018
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1MHQ
 | | Crystal Structure Of Human GGA2 VHS Domain | | Descriptor: | ADP-ribosylation factor binding protein GGA2 | | Authors: | Zhu, G, Zhang, X.C. | | Deposit date: | 2002-08-20 | | Release date: | 2003-03-11 | | Last modified: | 2017-10-11 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | Crystal structure of GGA2 VHS domain and its implication in plasticity in the ligand binding pocket
FEBS LETT., 537, 2003
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1MVX
 | | structure of the SET domain histone lysine methyltransferase Clr4 | | Descriptor: | CRYPTIC LOCI REGULATOR 4, NICKEL (II) ION, SULFATE ION, ... | | Authors: | Min, J.R, Zhang, X, Cheng, X.D, Grewal, S.I.S, Xu, R.-M. | | Deposit date: | 2002-09-26 | | Release date: | 2002-10-30 | | Last modified: | 2024-02-14 | | Method: | X-RAY DIFFRACTION (3 Å) | | Cite: | Structure of the SET domain histone lysine methyltransferase Clr4.
Nat.Struct.Biol., 9, 2002
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5X58
 | | Prefusion structure of SARS-CoV spike glycoprotein, conformation 1 | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein | | Authors: | Yuan, Y, Cao, D, Zhang, Y, Ma, J, Qi, J, Wang, Q, Lu, G, Wu, Y, Yan, J, Shi, Y, Zhang, X, Gao, G.F. | | Deposit date: | 2017-02-15 | | Release date: | 2017-05-03 | | Last modified: | 2020-07-29 | | Method: | ELECTRON MICROSCOPY (3.2 Å) | | Cite: | Cryo-EM structures of MERS-CoV and SARS-CoV spike glycoproteins reveal the dynamic receptor binding domains
Nat Commun, 8, 2017
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5TEB
 | | Crystal Structure of the TIR domain from the Arabidopsis Thaliana disease resistance protein RPP1 | | Descriptor: | Recognition of Peronospora parasitica 1 | | Authors: | Bentham, A.R, Zhang, X, Croll, T, Williams, S, Kobe, B. | | Deposit date: | 2016-09-20 | | Release date: | 2017-02-01 | | Last modified: | 2020-01-01 | | Method: | X-RAY DIFFRACTION (2.796 Å) | | Cite: | Multiple functional self-association interfaces in plant TIR domains.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
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1MVH
 | | structure of the SET domain histone lysine methyltransferase Clr4 | | Descriptor: | Cryptic loci regulator 4, NICKEL (II) ION, SULFATE ION, ... | | Authors: | Min, J.R, Zhang, X, Cheng, X.D, Grewal, S.I.S, Xu, R.-M. | | Deposit date: | 2002-09-25 | | Release date: | 2002-10-30 | | Last modified: | 2024-02-14 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | Structure of the SET domain histone lysine methyltransferase Clr4.
Nat.Struct.Biol., 9, 2002
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5X59
 | | Prefusion structure of MERS-CoV spike glycoprotein, three-fold symmetry | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, S protein | | Authors: | Yuan, Y, Cao, D, Zhang, Y, Ma, J, Qi, J, Wang, Q, Lu, G, Wu, Y, Yan, J, Shi, Y, Zhang, X, Gao, G.F. | | Deposit date: | 2017-02-15 | | Release date: | 2017-05-03 | | Last modified: | 2020-07-29 | | Method: | ELECTRON MICROSCOPY (3.7 Å) | | Cite: | Cryo-EM structures of MERS-CoV and SARS-CoV spike glycoproteins reveal the dynamic receptor binding domains
Nat Commun, 8, 2017
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