6K5L
 
 | | The crystal structure of isocitrate dehydrogenase kinase/phosphatase wtih two Mn2+ from E. coli | | 分子名称: | ADENOSINE MONOPHOSPHATE, ADENOSINE-5'-DIPHOSPHATE, Isocitrate dehydrogenase kinase/phosphatase, ... | | 著者 | Zhang, X, Lei, Z, Zheng, J, Jia, Z. | | 登録日 | 2019-05-29 | | 公開日 | 2019-07-03 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (2.55 Å) | | 主引用文献 | Characterization of metal binding of bifunctional kinase/phosphatase AceK and implication in activity modulation.
Sci Rep, 9, 2019
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7CBQ
 | | Crystal structure of PDE4D catalytic domain in complex with Apremilast | | 分子名称: | 1,2-ETHANEDIOL, MAGNESIUM ION, N-{2-[(1S)-1-(3-ethoxy-4-methoxyphenyl)-2-(methylsulfonyl)ethyl]-1,3-dioxo-2,3-dihydro-1H-isoindol-4-yl}acetamide, ... | | 著者 | Zhang, X.L, Xu, Y.C. | | 登録日 | 2020-06-13 | | 公開日 | 2021-01-27 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (1.59 Å) | | 主引用文献 | Design, synthesis, and biological evaluation of tetrahydroisoquinolines derivatives as novel, selective PDE4 inhibitors for antipsoriasis treatment.
Eur.J.Med.Chem., 211, 2021
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3RYT
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3SD6
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1J04
 | | Structural mechanism of enzyme mistargeting in hereditary kidney stone disease in vitro | | 分子名称: | (AMINOOXY)ACETIC ACID, GLYCEROL, alanine--glyoxylate aminotransferase | | 著者 | Zhang, X, Djordjevic, S, Bartlam, M, Ye, S, Rao, Z, Danpure, C.J. | | 登録日 | 2002-10-30 | | 公開日 | 2003-11-11 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | Structural implications of a G170R mutation of alanine:glyoxylate aminotransferase that is associated with peroxisome-to-mitochondrion mistargeting.
Acta Crystallogr.,Sect.F, 66, 2010
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4O9L
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7CTH
 | | Cryo-EM structure of dengue virus serotype 2 in complex with the scFv fragment of the broadly neutralizing antibody EDE1 C10 | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Core protein, Single Chain Variable Fragment | | 著者 | Zhang, X, Sharma, A, Duquerroy, S, Zhou, Z.H, Rey, F.A. | | 登録日 | 2020-08-19 | | 公開日 | 2021-12-01 | | 最終更新日 | 2022-02-16 | | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | | 主引用文献 | The epitope arrangement on flavivirus particles contributes to Mab C10's extraordinary neutralization breadth across Zika and dengue viruses.
Cell, 184, 2021
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8X2I
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8X2H
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4N6F
 | | Crystal structure of Amycolatopsis orientalis BexX complexed with G6P | | 分子名称: | CALCIUM ION, FRUCTOSE -6-PHOSPHATE, Putative thiosugar synthase | | 著者 | Zhang, X, Zhang, Y, Kinsland, C, Sasaki, E, Sun, H.G, Lu, M.J, Liu, T, Ou, A, Li, J, Chen, Y, Liu, H, Ealick, S.E. | | 登録日 | 2013-10-11 | | 公開日 | 2014-05-14 | | 最終更新日 | 2024-10-09 | | 実験手法 | X-RAY DIFFRACTION (2.25 Å) | | 主引用文献 | Co-opting sulphur-carrier proteins from primary metabolic pathways for 2-thiosugar biosynthesis.
Nature, 509, 2014
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7DVG
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4N6E
 | | Crystal structure of Amycolatopsis orientalis BexX/CysO complex | | 分子名称: | Putative thiosugar synthase, SULFATE ION, ThiS/MoaD family protein | | 著者 | Zhang, X, Zhang, Y, Kinsland, C, Sasaki, E, Sun, H.G, Lu, M.J, Liu, T, Ou, A, Li, J, Chen, Y, Liu, H, Ealick, S.E. | | 登録日 | 2013-10-11 | | 公開日 | 2014-05-14 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | Co-opting sulphur-carrier proteins from primary metabolic pathways for 2-thiosugar biosynthesis.
Nature, 509, 2014
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7FFF
 | | Structure of Venezuelan equine encephalitis virus with the receptor LDLRAD3 | | 分子名称: | CALCIUM ION, Capsid protein, Low-density lipoprotein receptor class A domain-containing protein 3, ... | | 著者 | Zhang, X, Xiang, Y, Ma, J, Ma, B, Huang, C. | | 登録日 | 2021-07-23 | | 公開日 | 2021-10-20 | | 最終更新日 | 2021-11-17 | | 実験手法 | ELECTRON MICROSCOPY (3 Å) | | 主引用文献 | Structure of Venezuelan equine encephalitis virus with its receptor LDLRAD3.
Nature, 598, 2021
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4O9F
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4OA7
 | | Crystal structure of Tankyrase1 in complex with IWR1 | | 分子名称: | 4-[(3aR,4R,7S,7aS)-1,3-dioxo-1,3,3a,4,7,7a-hexahydro-2H-4,7-methanoisoindol-2-yl]-N-(quinolin-8-yl)benzamide, Tankyrase-1, ZINC ION | | 著者 | Zhang, X, He, H. | | 登録日 | 2014-01-03 | | 公開日 | 2015-01-07 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (2.301 Å) | | 主引用文献 | Disruption of Wnt/ beta-Catenin Signaling and Telomeric Shortening Are Inextricable Consequences of Tankyrase Inhibition in Human Cells.
Mol.Cell.Biol., 35, 2015
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7DV8
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4Q2M
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6J6A
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4Q2L
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4PR3
 | | Crystal structure of Brucella melitensis 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase | | 分子名称: | 5'-methylthioadenosine nucleosidase / s-adenosylhomocysteine nucleosidase, ADENINE, GLYCEROL, ... | | 著者 | Zhang, X.C, Kang, X.S, Zhao, Y, Jiang, D.H, Li, X.M, Chen, Z.L. | | 登録日 | 2014-03-05 | | 公開日 | 2014-04-30 | | 実験手法 | X-RAY DIFFRACTION (2.606 Å) | | 主引用文献 | Crystal structure and biochemical studies of Brucella melitensis 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase
Biochem.Biophys.Res.Commun., 446, 2014
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2Q12
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7FFO
 | | Cryo-EM structure of VEEV VLP at the 5-fold axes | | 分子名称: | Capsid protein, Spike glycoprotein E1, Spike glycoprotein E2, ... | | 著者 | Zhang, X, Xiang, Y, Ma, J, Ma, B, Huang, C. | | 登録日 | 2021-07-23 | | 公開日 | 2021-10-20 | | 最終更新日 | 2021-11-17 | | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | | 主引用文献 | Structure of Venezuelan equine encephalitis virus with its receptor LDLRAD3.
Nature, 598, 2021
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7FFQ
 | | Cryo-EM structure of VEEV VLP at the 2-fold axes | | 分子名称: | Capsid protein, Spike glycoprotein E1, Spike glycoprotein E2, ... | | 著者 | Zhang, X, Xiang, Y, Ma, J, Ma, B, Huang, C. | | 登録日 | 2021-07-23 | | 公開日 | 2021-10-20 | | 最終更新日 | 2021-11-17 | | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | | 主引用文献 | Structure of Venezuelan equine encephalitis virus with its receptor LDLRAD3.
Nature, 598, 2021
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7FFE
 | | Cryo-EM structure of VEEV VLP | | 分子名称: | Capsid protein, Spike glycoprotein E1, Spike glycoprotein E2, ... | | 著者 | Zhang, X, Xiang, Y, Ma, J, Ma, B, Huang, C. | | 登録日 | 2021-07-23 | | 公開日 | 2021-10-20 | | 最終更新日 | 2021-11-17 | | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | | 主引用文献 | Structure of Venezuelan equine encephalitis virus with its receptor LDLRAD3.
Nature, 598, 2021
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7FFL
 | | Cryo-EM structure of VEEV VLP-LDLRAD3-D1 complex at the 2-fold axes | | 分子名称: | CALCIUM ION, Capsid protein, Low-density lipoprotein receptor class A domain-containing protein 3, ... | | 著者 | Zhang, X, Xiang, Y, Ma, J, Ma, B, Huang, C. | | 登録日 | 2021-07-23 | | 公開日 | 2021-10-20 | | 最終更新日 | 2021-11-17 | | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | | 主引用文献 | Structure of Venezuelan equine encephalitis virus with its receptor LDLRAD3.
Nature, 598, 2021
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