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PDB: 261 件
8WIE
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BU of 8wie by Molmil
Unlocking Immunogenic Potential: Innovating a Peptide/Ferritin Fusion Tag Nano-Delivery Platform from de novo design to Significantly Enhance Antigenicity of the Rabies Virus Glycoprotein Domain III
分子名称: CALCIUM ION, FE (III) ION, Peptide 10-1,Ferritin heavy chain
著者Fu, D, Wang, M, Guo, Y.
登録日2023-09-24
公開日2024-09-25
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Unlocking Immunogenic Potential: Innovating a Peptide/Ferritin Fusion Tag Nano-Delivery Platform from de novo design to Significantly Enhance Antigenicity of the Rabies Virus Glycoprotein Domain III
To Be Published
6BD4
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BU of 6bd4 by Molmil
Crystal structure of human apo-Frizzled4 receptor
分子名称: (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, Frizzled-4/Rubredoxin chimeric protein, OLEIC ACID, ...
著者Yang, S, Wu, Y, Pu, M, Chen, Y, Dong, S, Guo, Y, Han, G.Y, Stevens, R.C, Zhao, S, Xu, F.
登録日2017-10-21
公開日2018-08-22
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Crystal structure of the Frizzled 4 receptor in a ligand-free state.
Nature, 560, 2018
8WVZ
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BU of 8wvz by Molmil
Structure of ADP-Form AsfvPrimPol Hexamer
分子名称: ADENOSINE-5'-DIPHOSPHATE, DNA (25-MER), DNA (5'-D(P*AP*AP*AP*A)-3'), ...
著者Shi, T.H, Guo, Y.Y, Yan, R.H.
登録日2023-10-24
公開日2024-10-30
実験手法ELECTRON MICROSCOPY (3.15 Å)
主引用文献Structure of ADP-Form AsfvPrimPol Hexamer
To Be Published
6MOI
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BU of 6moi by Molmil
Dimeric DARPin C_angle_R5 complex with EpoR
分子名称: 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, Dimeric DARPing CCR5 (C_angle_R5), ...
著者Jude, K.M, Mohan, K, Garcia, K.C, Guo, Y.
登録日2018-10-04
公開日2019-06-05
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.065 Å)
主引用文献Topological control of cytokine receptor signaling induces differential effects in hematopoiesis.
Science, 364, 2019
6MOK
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BU of 6mok by Molmil
Dimeric DARPin A_distance_R7 complex with EpoR
分子名称: Dimeric DARPin ANR7 (A_distance_r7), Erythropoietin receptor
著者Jude, K.M, Mohan, K, Garcia, K.C, Guo, Y.
登録日2018-10-04
公開日2019-06-05
最終更新日2024-10-23
実験手法X-RAY DIFFRACTION (5.101 Å)
主引用文献Topological control of cytokine receptor signaling induces differential effects in hematopoiesis.
Science, 364, 2019
3F1P
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BU of 3f1p by Molmil
Crystal structure of a high affinity heterodimer of HIF2 alpha and ARNT C-terminal PAS domains
分子名称: Aryl hydrocarbon receptor nuclear translocator, Endothelial PAS domain-containing protein 1
著者Scheuermann, T.H, Tomchick, D.R, Machius, M, Guo, Y, Bruick, R.K, Gardner, K.H.
登録日2008-10-28
公開日2009-01-20
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.17 Å)
主引用文献Artificial ligand binding within the HIF2alpha PAS-B domain of the HIF2 transcription factor.
Proc.Natl.Acad.Sci.USA, 106, 2009
3CEY
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BU of 3cey by Molmil
Crystal structure of L3MBTL2
分子名称: Lethal(3)malignant brain tumor-like 2 protein
著者Nady, N, Guo, Y, Pan, P, Allali-Hassani, A, Qi, C, Zhu, H, Dong, A, Mackenzie, F, Crombet, L, Loppnau, P, Kozieradzki, I, Vedadi, M, Edwards, A.M, Weigelt, J, Bountra, C, Arrowsmith, C.H, Bochkarev, A, Read, R, Min, J, Structural Genomics Consortium (SGC)
登録日2008-02-29
公開日2008-05-06
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Methylation-state-specific recognition of histones by the MBT repeat protein L3MBTL2.
Nucleic Acids Res., 37, 2009
3F1O
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BU of 3f1o by Molmil
Crystal structure of the high affinity heterodimer of HIF2 alpha and ARNT C-terminal PAS domains, with an internally-bound artificial ligand
分子名称: 1,2-ETHANEDIOL, Aryl hydrocarbon receptor nuclear translocator, Endothelial PAS domain-containing protein 1, ...
著者Scheuermann, T.H, Tomchick, D.R, Machius, M, Guo, Y, Bruick, R.K, Gardner, K.H.
登録日2008-10-28
公開日2009-01-20
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.598 Å)
主引用文献Artificial ligand binding within the HIF2alpha PAS-B domain of the HIF2 transcription factor.
Proc.Natl.Acad.Sci.USA, 106, 2009
3F1N
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BU of 3f1n by Molmil
Crystal structure of a high affinity heterodimer of HIF2 alpha and ARNT C-terminal PAS domains, with internally bound ethylene glycol.
分子名称: 1,2-ETHANEDIOL, Aryl hydrocarbon receptor nuclear translocator, Endothelial PAS domain-containing protein 1
著者Scheuermann, T.H, Tomchick, D.R, Machius, M, Guo, Y, Bruick, R.K, Gardner, K.H.
登録日2008-10-28
公開日2009-01-20
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.479 Å)
主引用文献Artificial ligand binding within the HIF2alpha PAS-B domain of the HIF2 transcription factor.
Proc.Natl.Acad.Sci.USA, 106, 2009
8WFM
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BU of 8wfm by Molmil
Crystal structure of Omicron BA.1 in complex with a neutralizing antibody scFv T11
分子名称: Spike protein S1, T11 scFv
著者Zhang, M, Zhang, N, Gabibov, A, Guo, Y.
登録日2023-09-19
公開日2024-09-25
最終更新日2024-10-09
実験手法X-RAY DIFFRACTION (2.99 Å)
主引用文献Crystal structure of Omicron BA.1 in complex with a neutralizing antibody scFv T11
To Be Published
8WNS
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BU of 8wns by Molmil
Cryo EM map of SLC7A10 in the apo state
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Amino acid transporter heavy chain SLC3A2, Asc-type amino acid transporter 1
著者Li, Y.N, Guo, Y.Y, Dai, L, Yan, R.H.
登録日2023-10-06
公開日2024-05-15
最終更新日2024-10-16
実験手法ELECTRON MICROSCOPY (3.42 Å)
主引用文献Cryo-EM structure of the human Asc-1 transporter complex.
Nat Commun, 15, 2024
8WNY
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BU of 8wny by Molmil
Cryo EM map of SLC7A10-SLC3A2 complex in the D-serine bound state
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Amino acid transporter heavy chain SLC3A2, Asc-type amino acid transporter 1, ...
著者Li, Y.N, Guo, Y.Y, Dai, L, Yan, R.H.
登録日2023-10-06
公開日2024-05-15
実験手法ELECTRON MICROSCOPY (3.5 Å)
主引用文献Cryo-EM structure of the human Asc-1 transporter complex.
Nat Commun, 15, 2024
1XAR
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BU of 1xar by Molmil
Crystal Structure of a fragment of DC-SIGNR (containing the carbohydrate recognition domain and two repeats of the neck).
分子名称: CD209 antigen-like protein 1, SODIUM ION
著者Feinberg, H, Guo, Y, Mitchell, D.A, Drickamer, K, Weis, W.I.
登録日2004-08-26
公開日2004-11-16
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.25 Å)
主引用文献Extended Neck Regions Stabilize Tetramers of the Receptors DC-SIGN and DC-SIGNR
J.Biol.Chem., 280, 2005
8HW5
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BU of 8hw5 by Molmil
Crystal structure of African swine fever virus CP312R
分子名称: ACETIC ACID, CP312R
著者Wang, W.M, Wang, Z.Y, Fu, D, Guo, Y.
登録日2022-12-29
公開日2024-01-17
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献African swine fever virus CP312R is essential for virus replication and inhibits host protein expression by interacting with RPS27A
To Be Published
5I61
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BU of 5i61 by Molmil
Crystal structure of the RNA-dependent RNA polymerase of a human picorbirnavirus
分子名称: Potential RNA-dependent RNA polymerase
著者Collier, A.M, Guo, Y.R, Tao, Y.J.
登録日2016-02-15
公開日2016-03-16
最終更新日2019-12-11
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Initiation of RNA Polymerization and Polymerase Encapsidation by a Small dsRNA Virus.
Plos Pathog., 12, 2016
5I62
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BU of 5i62 by Molmil
Crystal structure of the insertion loop deletion mutant of the RNA-dependent RNA polymerase of a human picorbirnavirus
分子名称: Potential RNA-dependent RNA polymerase
著者Collier, A.M, Guo, Y.R, Tao, Y.J.
登録日2016-02-15
公開日2016-03-16
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.001 Å)
主引用文献Initiation of RNA Polymerization and Polymerase Encapsidation by a Small dsRNA Virus.
Plos Pathog., 12, 2016
2N17
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BU of 2n17 by Molmil
NMR structure of a Kazal-type serine protease inhibitor from the subterranean termite defense gland of Coptotermes formosanus Shiraki soldiers
分子名称: Lysozyme-Protease Inhibitor Protein
著者Negulescu, H, Guo, Y, Garner, T.P, Goodwin, O.Y, Henderson, G, Laine, R.A, Macnaughtan, M.A.
登録日2015-03-23
公開日2015-05-06
最終更新日2023-06-14
実験手法SOLUTION NMR
主引用文献A Kazal-Type Serine Protease Inhibitor from the Defense Gland Secretion of the Subterranean Termite Coptotermes formosanus Shiraki.
Plos One, 10, 2015
8H66
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BU of 8h66 by Molmil
Crystal structure of human GCN5 histone acetyltransferase domain bound with propionyl-CoA
分子名称: Histone acetyltransferase KAT2A, propionyl Coenzyme A
著者Li, N, Tao, Y.J, Guo, Y.R.
登録日2022-10-15
公開日2023-05-03
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Molecular Basis of KAT2A Selecting Acyl-CoA Cofactors for Histone Modifications.
Res, 6, 2023
8H6D
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BU of 8h6d by Molmil
Crystal structure of human GCN5 histone acetyltransferase domain bound with glutaryl-CoA
分子名称: Histone acetyltransferase KAT2A, glutaryl-coenzyme A
著者Li, N, Tao, Y.J, Guo, Y.R.
登録日2022-10-16
公開日2023-05-03
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (3.26 Å)
主引用文献Molecular Basis of KAT2A Selecting Acyl-CoA Cofactors for Histone Modifications.
Res, 6, 2023
8H6C
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BU of 8h6c by Molmil
Crystal structure of human GCN5 histone acetyltransferase domain bound with malonyl-CoA
分子名称: Histone acetyltransferase KAT2A, MALONYL-COENZYME A
著者Li, N, Tao, Y.J, Guo, Y.R.
登録日2022-10-16
公開日2023-05-03
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Molecular Basis of KAT2A Selecting Acyl-CoA Cofactors for Histone Modifications.
Res, 6, 2023
8H65
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BU of 8h65 by Molmil
Crystal structure of human GCN5 histone acetyltransferase domain bound with butyryl-CoA
分子名称: Butyryl Coenzyme A, Histone acetyltransferase KAT2A
著者Li, N, Tao, Y.J, Guo, Y.R.
登録日2022-10-15
公開日2023-05-03
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Molecular Basis of KAT2A Selecting Acyl-CoA Cofactors for Histone Modifications.
Res, 6, 2023
8HWD
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BU of 8hwd by Molmil
Cryo-EM Structure of D5 ADP form
分子名称: ADENOSINE-5'-DIPHOSPHATE, Primase D5
著者Li, Y.N, Zhu, J, Guo, Y.Y, Yan, R.H.
登録日2022-12-29
公開日2024-01-10
最終更新日2024-01-31
実験手法ELECTRON MICROSCOPY (3.3 Å)
主引用文献Structural insight into the assembly and working mechanism of helicase-primase D5 from Mpox virus.
Nat.Struct.Mol.Biol., 31, 2024
8HWB
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D5 ATP-ADP-Apo-ssDNA IS2
分子名称: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, DNA (5'-D(P*TP*TP*TP*TP*TP*T)-3'), ...
著者Li, Y.N, Zhu, J, Guo, Y.Y, Yan, R.H.
登録日2022-12-29
公開日2024-01-10
最終更新日2024-01-31
実験手法ELECTRON MICROSCOPY (3.9 Å)
主引用文献Structural insight into the assembly and working mechanism of helicase-primase D5 from Mpox virus.
Nat.Struct.Mol.Biol., 31, 2024
8HWA
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D5 ATP-ADP-Apo-ssDNA IS1
分子名称: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, DNA (5'-D(P*TP*TP*TP*TP*TP*T)-3'), ...
著者Li, Y.N, Zhu, J, Guo, Y.Y, Yan, R.H.
登録日2022-12-29
公開日2024-01-10
最終更新日2024-01-31
実験手法ELECTRON MICROSCOPY (3.7 Å)
主引用文献Structural insight into the assembly and working mechanism of helicase-primase D5 from Mpox virus.
Nat.Struct.Mol.Biol., 31, 2024
8HWG
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D5 ATPrS-ADP-ssDNA form
分子名称: ADENOSINE-5'-DIPHOSPHATE, DNA (5'-D(P*TP*TP*TP*TP*TP*T)-3'), MAGNESIUM ION, ...
著者Li, Y.N, Zhu, J, Guo, Y.Y, Yan, R.H.
登録日2022-12-29
公開日2024-01-10
最終更新日2024-01-31
実験手法ELECTRON MICROSCOPY (3 Å)
主引用文献Structural insight into the assembly and working mechanism of helicase-primase D5 from Mpox virus.
Nat.Struct.Mol.Biol., 31, 2024

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