6BD4

Crystal structure of human apo-Frizzled4 receptor

Summary for 6BD4

• Entry DOI: 10.2210/pdb6bd4/pdb
• Descriptor: Frizzled-4/Rubredoxin chimeric protein, ZINC ION, (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, ... (7 entities in total)
• Functional Keywords: gpcr, frizzled, apo, membrane protein
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 1
• Total formula weight: 51007.00

Authors

Yang, S.,Wu, Y.,Pu, M.,Chen, Y.,Dong, S.,Guo, Y.,Han, G.Y.,Stevens, R.C.,Zhao, S.,Xu, F. (deposition date: 2017-10-21, release date: 2018-08-22, Last modification date: 2023-10-04)

• Primary citation: Yang, S.,Wu, Y.,Xu, T.H.,de Waal, P.W.,He, Y.,Pu, M.,Chen, Y.,DeBruine, Z.J.,Zhang, B.,Zaidi, S.A.,Popov, P.,Guo, Y.,Han, G.W.,Lu, Y.,Suino-Powell, K.,Dong, S.,Harikumar, K.G.,Miller, L.J.,Katritch, V.,Xu, H.E.,Shui, W.,Stevens, R.C.,Melcher, K.,Zhao, S.,Xu, F.; Crystal structure of the Frizzled 4 receptor in a ligand-free state.; Nature, 560:666-670, 2018; PubMed: 30135577; DOI: 10.1038/s41586-018-0447-x

Experimental method

X-RAY DIFFRACTION (2.4 Å)