6BD4
Crystal structure of human apo-Frizzled4 receptor
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Frizzled-4/Rubredoxin chimeric protein | polymer | 420 | 47814.9 | 1 | UniProt (Q9ULV1) UniProt (P00268) Pfam (PF01534) Pfam (PF00301) | Homo sapiens (Human) | |
| 2 | B (A) | ZINC ION | non-polymer | 65.4 | 1 | Chemie (ZN) | |||
| 3 | C, D, E, F (A) | (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate | non-polymer | 356.5 | 4 | Chemie (OLC) | |||
| 4 | G, H, I, J, K (A) | OLEIC ACID | non-polymer | 282.5 | 5 | Chemie (OLA) | |||
| 5 | L, M, N (A) | SULFATE ION | non-polymer | 96.1 | 3 | Chemie (SO4) | |||
| 6 | O, P, Q, R (A) | UNKNOWN ATOM OR ION | non-polymer | 4 | Chemie (UNX) | ||||
| 7 | S (A) | water | water | 18.0 | 23 | Chemie (HOH) |
Sequence modifications
A: 178 - 419 (UniProt: Q9ULV1)
A: 1001 - 1054 (UniProt: P00268)
A: 428 - 517 (UniProt: Q9ULV1)
| PDB | External Database | Details |
|---|---|---|
| Asp 144 | - | expression tag |
| Tyr 145 | - | expression tag |
| Lys 146 | - | expression tag |
| Asp 147 | - | expression tag |
| Asp 148 | - | expression tag |
| Asp 149 | - | expression tag |
| Asp 150 | - | expression tag |
| Ala 151 | - | expression tag |
| Lys 152 | - | expression tag |
| Leu 153 | - | expression tag |
| Gln 154 | - | expression tag |
| Thr 155 | - | expression tag |
| Met 156 | - | expression tag |
| His 157 | - | expression tag |
| His 158 | - | expression tag |
| His 159 | - | expression tag |
| His 160 | - | expression tag |
| His 161 | - | expression tag |
| His 162 | - | expression tag |
| His 163 | - | expression tag |
| His 164 | - | expression tag |
| His 165 | - | expression tag |
| His 166 | - | expression tag |
| Glu 167 | - | expression tag |
| Asn 168 | - | expression tag |
| Leu 169 | - | expression tag |
| Tyr 170 | - | expression tag |
| Phe 171 | - | expression tag |
| Gln 172 | - | expression tag |
| Gly 173 | - | expression tag |
| Gly 174 | - | expression tag |
| Thr 175 | - | expression tag |
| Leu 176 | - | expression tag |
| Glu 177 | - | expression tag |
| Leu 309 | Met 309 | engineered mutation |
A: 428 - 517 (UniProt: Q9ULV1)
| PDB | External Database | Details |
|---|---|---|
| Ile 450 | Cys 450 | engineered mutation |
| Phe 507 | Cys 507 | engineered mutation |
| Tyr 508 | Ser 508 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 47814.9 | |
| Non-Polymers* | Number of molecules | 17 |
| Total formula weight | 3192.1 | |
| All* | Total formula weight | 51007.0 |
