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PDB: 98 件

1RC9
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Crystal Structure of Stecrisp, a Member of CRISP Family from Trimeresurus Stejnegeri Refined at 1.6 Angstroms Resolution: Structual relationship of the two domains
分子名称: cysteine-rich secretory protein
著者Guo, M, Teng, M, Niu, L.
登録日2003-11-03
公開日2005-01-11
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Crystal structure of cysteine-rich secretory protein stecrisp reveals the cysteine-rich domain has a K+-channel inhibitor-like fold.
J.Biol.Chem., 280, 2004
8J7S
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BU of 8j7s by Molmil
Structure of the SPARTA complex
分子名称: DNA (5'-D(P*TP*AP*AP*TP*AP*GP*AP*TP*TP*AP*GP*AP*GP*CP*CP*GP*TP*CP*AP*AP*TP*AP*GP*A)-3'), Piwi domain-containing protein, RNA (5'-R(P*UP*GP*AP*CP*GP*GP*CP*UP*CP*UP*AP*AP*UP*CP*UP*AP*UP*UP*A)-3'), ...
著者Guo, M, Zhu, Y, Lin, Z, Huang, Z.
登録日2023-04-28
公開日2024-03-06
実験手法ELECTRON MICROSCOPY (2.84 Å)
主引用文献Cryo-EM structure of the ssDNA-activated SPARTA complex.
Cell Res., 33, 2023
1S6V
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BU of 1s6v by Molmil
Structure of a cytochrome c peroxidase-cytochrome c site specific cross-link
分子名称: Cytochrome c peroxidase, mitochondrial, Cytochrome c, ...
著者Guo, M, Bhaskar, B, Li, H, Barrows, T.P, Poulos, T.L.
登録日2004-01-27
公開日2004-04-27
最終更新日2024-10-09
実験手法X-RAY DIFFRACTION (1.88 Å)
主引用文献Crystal structure and characterization of a cytochrome c peroxidase-cytochrome c site-specific cross-link
Proc.Natl.Acad.Sci.USA, 101, 2004
3BJU
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BU of 3bju by Molmil
Crystal Structure of tetrameric form of human lysyl-tRNA synthetase
分子名称: ADENOSINE-5'-TRIPHOSPHATE, CALCIUM ION, LYSINE, ...
著者Guo, M, Yang, X.L, Schimmel, P.
登録日2007-12-04
公開日2008-02-05
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.31 Å)
主引用文献Crystal structure of tetrameric form of human lysyl-tRNA synthetase: Implications for multisynthetase complex formation
Proc.Natl.Acad.Sci.Usa, 105, 2008
3HXU
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BU of 3hxu by Molmil
Crystal Structure of catalytic fragment of E. coli AlaRS in complex with AlaSA
分子名称: '5'-O-(N-(L-ALANYL)-SULFAMOYL)ADENOSINE, 2-HYDROXYETHYL DISULFIDE, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ...
著者Guo, M, Yang, X.-L, Schimmel, P.
登録日2009-06-22
公開日2009-12-15
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Paradox of mistranslation of serine for alanine caused by AlaRS recognition dilemma.
Nature, 462, 2009
3HXV
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Crystal Structure of catalytic fragment of E. coli AlaRS in complex with GlySA
分子名称: 2-HYDROXYETHYL DISULFIDE, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, 5'-O-(glycylsulfamoyl)adenosine, ...
著者Guo, M, Yang, X.-L, Schimmel, P.
登録日2009-06-22
公開日2009-12-15
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (1.93 Å)
主引用文献Paradox of mistranslation of serine for alanine caused by AlaRS recognition dilemma.
Nature, 462, 2009
3HXY
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Crystal Structure of catalytic fragment of E. coli AlaRS in complex with AMPPCP, Ala-AMP and PCP
分子名称: 2-HYDROXYETHYL DISULFIDE, 5'-O-[(R)-{[(2S)-2-aminopropanoyl]oxy}(hydroxy)phosphoryl]adenosine, Alanyl-tRNA synthetase, ...
著者Guo, M, Yang, X.-L, Schimmel, P.
登録日2009-06-22
公開日2009-12-15
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.27 Å)
主引用文献Paradox of mistranslation of serine for alanine caused by AlaRS recognition dilemma.
Nature, 462, 2009
3HXW
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Crystal Structure of catalytic fragment of E. coli AlaRS in complex with SerSA
分子名称: 2-HYDROXYETHYL DISULFIDE, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, 5'-O-(N-(L-SERYL)-SULFAMOYL)ADENOSINE, ...
著者Guo, M, Yang, X.-L, Schimmel, P.
登録日2009-06-22
公開日2009-12-15
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (1.93 Å)
主引用文献Paradox of mistranslation of serine for alanine caused by AlaRS recognition dilemma.
Nature, 462, 2009
3HTZ
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BU of 3htz by Molmil
Crystal Structure of the catalytic fragment of alanyl-tRNA synthetase in complex with L-serine: Re-refined
分子名称: Alanyl-tRNA synthetase
著者Guo, M, Swairjo, M.A, Schimmel, P.
登録日2009-06-12
公開日2009-06-30
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Serine Paradox
To be Published
3HXZ
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BU of 3hxz by Molmil
Crystal Structure of catalytic fragment of E. coli AlaRS G237A in complex with AlaSA
分子名称: '5'-O-(N-(L-ALANYL)-SULFAMOYL)ADENOSINE, 2-HYDROXYETHYL DISULFIDE, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ...
著者Guo, M, Yang, X.-L, Schimmel, P.
登録日2009-06-22
公開日2009-12-15
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (1.99 Å)
主引用文献Paradox of mistranslation of serine for alanine caused by AlaRS recognition dilemma.
Nature, 462, 2009
3HY1
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BU of 3hy1 by Molmil
Crystal Structure of catalytic fragment of E. coli AlaRS G237A in complex with SerSA
分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 2-HYDROXYETHYL DISULFIDE, 5'-O-(N-(L-SERYL)-SULFAMOYL)ADENOSINE, ...
著者Guo, M, Yang, X.-L, Schimmel, P.
登録日2009-06-22
公開日2009-12-15
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.79 Å)
主引用文献Paradox of mistranslation of serine for alanine caused by AlaRS recognition dilemma.
Nature, 462, 2009
3G98
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BU of 3g98 by Molmil
Crystal Structure of the C-Ala domain from Aquifex aeolicus alanyl-tRNA synthetase
分子名称: Alanyl-tRNA synthetase
著者Guo, M, Yang, X.L, Schimmel, P.
登録日2009-02-13
公開日2009-10-06
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献The C-Ala domain brings together editing and aminoacylation functions on one tRNA.
Science, 325, 2009
3HY0
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BU of 3hy0 by Molmil
Crystal Structure of catalytic fragment of E. coli AlaRS G237A in complex with GlySA
分子名称: 2-HYDROXYETHYL DISULFIDE, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, 5'-O-(glycylsulfamoyl)adenosine, ...
著者Guo, M, Yang, X.-L, Schimmel, P.
登録日2009-06-22
公開日2009-12-15
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Paradox of mistranslation of serine for alanine caused by AlaRS recognition dilemma.
Nature, 462, 2009
3HXX
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BU of 3hxx by Molmil
Crystal Structure of catalytic fragment of E. coli AlaRS in complex with AMPPCP
分子名称: Alanyl-tRNA synthetase, MAGNESIUM ION, PHOSPHOMETHYLPHOSPHONIC ACID ADENYLATE ESTER
著者Guo, M, Yang, X.-L, Schimmel, P.
登録日2009-06-22
公開日2009-12-15
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.11 Å)
主引用文献Paradox of mistranslation of serine for alanine caused by AlaRS recognition dilemma.
Nature, 462, 2009
8HLM
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BU of 8hlm by Molmil
Crystal structure of p53/BCL2 fusion complex (complex 2)
分子名称: Apoptosis regulator Bcl-2, Cellular tumor antigen p53, ZINC ION
著者Guo, M, Wang, H, Wei, H, Chen, Y.
登録日2022-11-30
公開日2023-07-26
最終更新日2024-05-29
実験手法X-RAY DIFFRACTION (2.522 Å)
主引用文献Structures of p53/BCL-2 complex suggest a mechanism for p53 to antagonize BCL-2 activity.
Nat Commun, 14, 2023
8HLN
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BU of 8hln by Molmil
Crystal structure of p53/BCL2 fusion complex(complex3)
分子名称: Apoptosis regulator Bcl-2, Cellular tumor antigen p53, ZINC ION
著者Guo, M, Wei, H, Wang, H, Chen, Y.
登録日2022-11-30
公開日2023-07-26
最終更新日2024-05-29
実験手法X-RAY DIFFRACTION (2.354 Å)
主引用文献Structures of p53/BCL-2 complex suggest a mechanism for p53 to antagonize BCL-2 activity.
Nat Commun, 14, 2023
6L8L
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BU of 6l8l by Molmil
C-Src in complex with ibrutinib
分子名称: 1-{(3R)-3-[4-amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl]piperidin-1-yl}prop-2-en-1-one, Proto-oncogene tyrosine-protein kinase Src
著者Guo, M, Dai, S, Chen, L, Chen, Y.
登録日2019-11-06
公開日2020-11-11
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.888 Å)
主引用文献Characterization of ibrutinib as a non-covalent inhibitor of SRC-family kinases.
Bioorg.Med.Chem.Lett., 34, 2020
5XP7
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BU of 5xp7 by Molmil
C-Src in complex with ATP-CHCl
分子名称: GLYCEROL, MAGNESIUM ION, Proto-oncogene tyrosine-protein kinase Src, ...
著者Guo, M, Dai, S, Duan, Y, Chen, L, Chen, Y.
登録日2017-06-01
公開日2017-09-06
最終更新日2024-03-27
実験手法X-RAY DIFFRACTION (2.012 Å)
主引用文献Remarkably Stereospecific Utilization of ATP alpha , beta-Halomethylene Analogues by Protein Kinases.
J. Am. Chem. Soc., 139, 2017
6AEG
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BU of 6aeg by Molmil
Crystal structure of xCas9 in complex with sgRNA and target DNA (GAT PAM)
分子名称: DNA (25-MER), DNA (5'-D(*AP*AP*AP*GP*AP*TP*TP*AP*TP*TP*G)-3'), DNA nuclease, ...
著者Guo, M, Ren, K, Zhu, Y, Huang, Z.
登録日2018-08-04
公開日2019-03-27
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.701 Å)
主引用文献Structural insights into a high fidelity variant of SpCas9.
Cell Res., 29, 2019
6AEB
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BU of 6aeb by Molmil
Crystal structure of xCas9 in complex with sgRNA and target DNA (AAG PAM)
分子名称: DNA (25-MER), DNA (5'-D(*AP*AP*AP*AP*AP*GP*TP*AP*TP*TP*G)-3'), DNA Nuclease, ...
著者Guo, M, Ren, K, Zhu, Y, Huang, Z.
登録日2018-08-04
公開日2019-03-27
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (3.004 Å)
主引用文献Structural insights into a high fidelity variant of SpCas9.
Cell Res., 29, 2019
7WF5
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BU of 7wf5 by Molmil
c-Src in complex with ponatinib
分子名称: 3-(imidazo[1,2-b]pyridazin-3-ylethynyl)-4-methyl-N-{4-[(4-methylpiperazin-1-yl)methyl]-3-(trifluoromethyl)phenyl}benzam ide, Proto-oncogene tyrosine-protein kinase Src
著者Guo, M, Duan, Y, Dai, S, Chen, X, Chen, Y.
登録日2021-12-26
公開日2022-03-02
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.798 Å)
主引用文献Structural study of ponatinib in inhibiting SRC kinase.
Biochem.Biophys.Res.Commun., 598, 2022
7D8T
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BU of 7d8t by Molmil
MITF bHLHLZ complex with M-box DNA
分子名称: DNA (5'-D(*TP*GP*TP*AP*AP*CP*AP*TP*GP*TP*GP*TP*CP*CP*CP*C)-3'), DNA (5'-D(P*GP*GP*GP*AP*CP*AP*CP*AP*TP*GP*TP*TP*AP*CP*AP*G)-3'), Microphthalmia-associated transcription factor,Methionyl-tRNA synthetase beta subunit
著者Guo, M, Fang, P, Wang, J.
登録日2020-10-09
公開日2021-10-13
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (3.201 Å)
主引用文献A unique hyperdynamic dimer interface permits small molecule perturbation of the melanoma oncoprotein MITF for melanoma therapy.
Cell Res., 33, 2023
7D8R
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BU of 7d8r by Molmil
MITF HLHLZ structure
分子名称: Microphthalmia-associated transcription factor,Methionyl-tRNA synthetase beta subunit
著者Guo, M, Fang, P, Wang, J.
登録日2020-10-09
公開日2021-10-13
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献A unique hyperdynamic dimer interface permits small molecule perturbation of the melanoma oncoprotein MITF for melanoma therapy.
Cell Res., 33, 2023
7D8S
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BU of 7d8s by Molmil
MITF bHLHLZ apo structure
分子名称: Microphthalmia-associated transcription factor,Methionyl-tRNA synthetase beta subunit, SULFATE ION
著者Guo, M, Fang, P, Wang, J.
登録日2020-10-09
公開日2021-10-13
最終更新日2024-10-23
実験手法X-RAY DIFFRACTION (2.28 Å)
主引用文献A unique hyperdynamic dimer interface permits small molecule perturbation of the melanoma oncoprotein MITF for melanoma therapy.
Cell Res., 33, 2023
7COC
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BU of 7coc by Molmil
Ternary complex of DNA polymerase Mu (K438A/Q441A) with 1-nt gapped DNA (T:dGMPNPP)
分子名称: 2'-deoxy-5'-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]guanosine, DNA (5'-D(*CP*GP*GP*CP*TP*TP*AP*CP*G)-3'), DNA (5'-D(*CP*GP*TP*A)-3'), ...
著者Guo, M, Zhao, Y.
登録日2020-08-04
公開日2021-06-30
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Mechanism of genome instability mediated by human DNA polymerase mu misincorporation.
Nat Commun, 12, 2021

 

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