6AEB
Crystal structure of xCas9 in complex with sgRNA and target DNA (AAG PAM)
Summary for 6AEB
Entry DOI | 10.2210/pdb6aeb/pdb |
Descriptor | RNA (95-MER), DNA (25-MER), DNA (5'-D(*AP*AP*AP*AP*AP*GP*TP*AP*TP*TP*G)-3'), ... (5 entities in total) |
Functional Keywords | enzyme, dna binding protein-rna complex, dna binding protein/rna |
Biological source | Streptococcus pyogenes More |
Total number of polymer chains | 8 |
Total formula weight | 405543.75 |
Authors | |
Primary citation | Guo, M.,Ren, K.,Zhu, Y.,Tang, Z.,Wang, Y.,Zhang, B.,Huang, Z. Structural insights into a high fidelity variant of SpCas9. Cell Res., 29:183-192, 2019 Cited by PubMed: 30664728DOI: 10.1038/s41422-018-0131-6 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3.004 Å) |
Structure validation
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