7JVP
 
 | | Cryo-EM structure of SKF-83959-bound dopamine receptor 1 in complex with Gs protein | | 分子名称: | (1R)-6-chloro-3-methyl-1-(3-methylphenyl)-2,3,4,5-tetrahydro-1H-3-benzazepine-7,8-diol, CHOLESTEROL, D(1A) dopamine receptor, ... | | 著者 | Zhuang, Y, Xu, P, Mao, C, Wang, L, Krumm, B, Zhou, X.E, Huang, S, Liu, H, Cheng, X, Huang, X.-P, Sheng, D.-D, Xu, T, Liu, Y.-F, Wang, Y, Guo, J, Jiang, Y, Jiang, H, Melcher, K, Roth, B.L, Zhang, Y, Zhang, C, Xu, H.E. | | 登録日 | 2020-08-22 | | 公開日 | 2021-02-24 | | 最終更新日 | 2021-03-03 | | 実験手法 | ELECTRON MICROSCOPY (2.9 Å) | | 主引用文献 | Structural insights into the human D1 and D2 dopamine receptor signaling complexes.
Cell, 184, 2021
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7JV5
 | | Cryo-EM structure of SKF-81297-bound dopamine receptor 1 in complex with Gs protein | | 分子名称: | (1R)-6-chloro-1-phenyl-2,3,4,5-tetrahydro-1H-3-benzazepine-7,8-diol, CHOLESTEROL, D(1A) dopamine receptor, ... | | 著者 | Zhuang, Y, Xu, P, Mao, C, Wang, L, Krumm, B, Zhou, X.E, Huang, S, Liu, H, Cheng, X, Huang, X.-P, Sheng, D.-D, Xu, T, Liu, Y.-F, Wang, Y, Guo, J, Jiang, Y, Jiang, H, Melcher, K, Roth, B.L, Zhang, Y, Zhang, C, Xu, H.E. | | 登録日 | 2020-08-20 | | 公開日 | 2021-02-24 | | 最終更新日 | 2021-03-03 | | 実験手法 | ELECTRON MICROSCOPY (3 Å) | | 主引用文献 | Structural insights into the human D1 and D2 dopamine receptor signaling complexes.
Cell, 184, 2021
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7JVR
 | | Cryo-EM structure of Bromocriptine-bound dopamine receptor 2 in complex with Gi protein | | 分子名称: | Antibody fragment ScFv16, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... | | 著者 | Zhuang, Y, Xu, P, Mao, C, Wang, L, Krumm, B, Zhou, X.E, Huang, S, Liu, H, Cheng, X, Huang, X.-P, Sheng, D.-D, Xu, T, Liu, Y.-F, Wang, Y, Guo, J, Jiang, Y, Jiang, H, Melcher, K, Roth, B.L, Zhang, Y, Zhang, C, Xu, H.E. | | 登録日 | 2020-08-22 | | 公開日 | 2021-02-24 | | 最終更新日 | 2024-10-23 | | 実験手法 | ELECTRON MICROSCOPY (2.8 Å) | | 主引用文献 | Structural insights into the human D1 and D2 dopamine receptor signaling complexes.
Cell, 184, 2021
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8YG8
 | | The early intermediate structure of baculovirus fusion protein GP64 | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Major envelope glycoprotein | | 著者 | Du, D, Guo, J, Li, S. | | 登録日 | 2024-02-26 | | 公開日 | 2024-09-11 | | 最終更新日 | 2024-09-18 | | 実験手法 | ELECTRON MICROSCOPY (2.97 Å) | | 主引用文献 | Structural transition of GP64 triggered by a pH-sensitive multi-histidine switch.
Nat Commun, 15, 2024
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8YG6
 | | The pre-fusion structure of baculovirus fusion protein GP64 | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Major envelope glycoprotein | | 著者 | Du, D, Guo, J, Li, S. | | 登録日 | 2024-02-26 | | 公開日 | 2024-09-11 | | 最終更新日 | 2024-10-30 | | 実験手法 | ELECTRON MICROSCOPY (2.77 Å) | | 主引用文献 | Structural transition of GP64 triggered by a pH-sensitive multi-histidine switch.
Nat Commun, 15, 2024
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1YQY
 | | Structure of B. Anthrax Lethal factor in complex with a hydroxamate inhibitor | | 分子名称: | (2R)-2-{[(4-FLUORO-3-METHYLPHENYL)SULFONYL]AMINO}-N-HYDROXY-2-TETRAHYDRO-2H-PYRAN-4-YLACETAMIDE, Lethal factor, ZINC ION | | 著者 | Shoop, W.L, Xiong, Y, Wiltsie, J, Woods, A, Guo, J, Pivnichny, J.V, Felcetto, T, Michael, B.F, Bansal, A. | | 登録日 | 2005-02-02 | | 公開日 | 2005-05-31 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Anthrax lethal factor inhibition.
Proc.Natl.Acad.Sci.Usa, 102, 2005
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5CB0
 | | Crystal structure and functional implications of the tandem-type universal stress protein UspE from Escherichia coli | | 分子名称: | 3-oxotetradecanoic acid, Universal stress protein E | | 著者 | Xu, Y, Quan, C.S, Jin, X, Jin, L, Kim, J.S, Guo, J, Fan, S, Ha, N.C. | | 登録日 | 2015-06-30 | | 公開日 | 2016-02-10 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (3.207 Å) | | 主引用文献 | Crystal structure and functional implications of the tandem-type universal stress protein UspE from Escherichia coli.
Bmc Struct.Biol., 16, 2016
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5F6T
 | | Structure of calexcitin-Gd3+ complex. | | 分子名称: | CALCIUM ION, Calexcitin, GADOLINIUM ATOM | | 著者 | Chataigner, L, Guo, J, Erskine, P.T, Coker, A.R, Wood, S.P, Cooper, J.B. | | 登録日 | 2015-12-06 | | 公開日 | 2015-12-16 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (2.201 Å) | | 主引用文献 | Binding of Gd(3+) to the neuronal signalling protein calexcitin identifies an exchangeable Ca(2+)-binding site.
Acta Crystallogr.,Sect.F, 72, 2016
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8IRL
 | | Apo state of Arabidopsis AZG1 at pH 7.4 | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Adenine/guanine permease AZG1 | | 著者 | Xu, L, Guo, J. | | 登録日 | 2023-03-19 | | 公開日 | 2024-01-17 | | 最終更新日 | 2024-02-07 | | 実験手法 | ELECTRON MICROSCOPY (2.7 Å) | | 主引用文献 | Structures and mechanisms of the Arabidopsis cytokinin transporter AZG1.
Nat.Plants, 10, 2024
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8IRN
 | | 6-BAP bound state of Arabidopsis AZG1 | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Adenine/guanine permease AZG1, N-BENZYL-9H-PURIN-6-AMINE | | 著者 | Xu, L, Guo, J. | | 登録日 | 2023-03-19 | | 公開日 | 2024-01-17 | | 最終更新日 | 2024-10-30 | | 実験手法 | ELECTRON MICROSCOPY (2.7 Å) | | 主引用文献 | Structures and mechanisms of the Arabidopsis cytokinin transporter AZG1.
Nat.Plants, 10, 2024
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8IRP
 | | kinetin bound state of Arabidopsis AZG1 | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Adenine/guanine permease AZG1, N-(FURAN-2-YLMETHYL)-7H-PURIN-6-AMINE | | 著者 | Xu, L, Guo, J. | | 登録日 | 2023-03-19 | | 公開日 | 2024-01-17 | | 最終更新日 | 2024-10-23 | | 実験手法 | ELECTRON MICROSCOPY (2.8 Å) | | 主引用文献 | Structures and mechanisms of the Arabidopsis cytokinin transporter AZG1.
Nat.Plants, 10, 2024
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8IRM
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8IRO
 | | trans-Zeatin bound state of Arabidopsis AZG1 at pH7.4 | | 分子名称: | (2E)-2-methyl-4-(9H-purin-6-ylamino)but-2-en-1-ol, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Adenine/guanine permease AZG1 | | 著者 | Xu, L, Guo, J. | | 登録日 | 2023-03-19 | | 公開日 | 2024-01-17 | | 最終更新日 | 2024-10-23 | | 実験手法 | ELECTRON MICROSCOPY (2.7 Å) | | 主引用文献 | Structures and mechanisms of the Arabidopsis cytokinin transporter AZG1.
Nat.Plants, 10, 2024
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3P2M
 | | Crystal Structure of a Novel Esterase Rv0045c from Mycobacterium tuberculosis | | 分子名称: | POSSIBLE HYDROLASE | | 著者 | Zheng, X.D, Guo, J, Xu, L, Li, H, Zhang, D, Zhang, K, Sun, F, Wen, T, Liu, S, Pang, H. | | 登録日 | 2010-10-03 | | 公開日 | 2011-07-06 | | 最終更新日 | 2024-03-20 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Crystal Structure of a Novel Esterase Rv0045c from Mycobacterium tuberculosis
Plos One, 6, 2011
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3DX2
 | | Golgi mannosidase II complex with MANNOSTATIN B | | 分子名称: | (1R,2R,3R,4S,5R)-4-amino-5-[(R)-methylsulfinyl]cyclopentane-1,2,3-triol, (4R)-2-METHYLPENTANE-2,4-DIOL, (4S)-2-METHYL-2,4-PENTANEDIOL, ... | | 著者 | Kuntz, D.A, Zhong, W, Guo, J, Rose, D.R, Boons, G.-J. | | 登録日 | 2008-07-23 | | 公開日 | 2009-07-07 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | | 主引用文献 | The molecular basis of inhibition of Golgi alpha-mannosidase II by mannostatin A.
Chembiochem, 10, 2009
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4NVQ
 | | Human G9a in Complex with Inhibitor A-366 | | 分子名称: | 5'-methoxy-6'-[3-(pyrrolidin-1-yl)propoxy]spiro[cyclobutane-1,3'-indol]-2'-amine, Histone-lysine N-methyltransferase EHMT2, S-ADENOSYL-L-HOMOCYSTEINE, ... | | 著者 | Sweis, R.F, Pliushchev, M, Brown, P.J, Guo, J, Li, F, Maag, D, Petros, A.M, Soni, N.B, Tse, C, Vedadi, M, Michaelides, M.R, Chiang, G.G, Pappano, W.N. | | 登録日 | 2013-12-05 | | 公開日 | 2014-01-15 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (2.03 Å) | | 主引用文献 | Discovery and development of potent and selective inhibitors of histone methyltransferase g9a.
ACS Med Chem Lett, 5, 2014
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4P9G
 | | Structure of the 2,4'-dihydroxyacetophenone dioxygenase from Alcaligenes sp. | | 分子名称: | 2,4'-dihydroxyacetophenone dioxygenase, CARBONATE ION, FE (III) ION, ... | | 著者 | Keegan, R, Lebedev, A, Erskine, P, Guo, J, Wood, S.P, Hopper, D.J, Cooper, J.B. | | 登録日 | 2014-04-03 | | 公開日 | 2014-09-10 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Structure of the 2,4'-dihydroxyacetophenone dioxygenase from Alcaligenes sp. 4HAP
Acta Crystallogr.,Sect.D, 70, 2014
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7LJC
 | | Allosteric modulator LY3154207 binding to SKF-81297-bound dopamine receptor 1 in complex with miniGs protein | | 分子名称: | (1R)-6-chloro-1-phenyl-2,3,4,5-tetrahydro-1H-3-benzazepine-7,8-diol, 2-[2,6-bis(chloranyl)phenyl]-1-[(1S,3R)-3-(hydroxymethyl)-1-methyl-5-(3-methyl-3-oxidanyl-butyl)-3,4-dihydro-1H-isoquinolin-2-yl]ethanone, CHOLESTEROL, ... | | 著者 | Zhuang, Y, Krumm, B, Zhang, H, Zhou, X.E, Wang, Y, Guo, J, Huang, X.-P, Liu, Y, Wang, L, Cheng, X, Jiang, Y, Jiang, H, Melcher, K, Zhang, C, Yi, W, Roth, B.L, Zhang, Y, Xu, H.E. | | 登録日 | 2021-01-28 | | 公開日 | 2021-03-03 | | 最終更新日 | 2021-05-12 | | 実験手法 | ELECTRON MICROSCOPY (3 Å) | | 主引用文献 | Mechanism of dopamine binding and allosteric modulation of the human D1 dopamine receptor.
Cell Res., 31, 2021
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7LJD
 | | Allosteric modulator LY3154207 binding to dopamine-bound dopamine receptor 1 in complex with miniGs protein | | 分子名称: | 2-[2,6-bis(chloranyl)phenyl]-1-[(1S,3R)-3-(hydroxymethyl)-1-methyl-5-(3-methyl-3-oxidanyl-butyl)-3,4-dihydro-1H-isoquinolin-2-yl]ethanone, CHOLESTEROL, D(1A) dopamine receptor, ... | | 著者 | Zhuang, Y, Krumm, B, Zhang, H, Zhou, X.E, Wang, Y, Guo, J, Huang, X.-P, Liu, Y, Wang, L, Cheng, X, Jiang, Y, Jiang, H, Melcher, K, Zhang, C, Yi, W, Roth, B.L, Zhang, Y, Xu, H.E. | | 登録日 | 2021-01-28 | | 公開日 | 2021-03-03 | | 最終更新日 | 2024-10-30 | | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | | 主引用文献 | Mechanism of dopamine binding and allosteric modulation of the human D1 dopamine receptor.
Cell Res., 31, 2021
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7XW9
 | | Cryo-EM structure of the TRH-bound human TRHR-Gq complex | | 分子名称: | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(q) subunit alpha, ... | | 著者 | Ji, S, Dong, Y, Chen, L, Zang, S, Shen, D, Guo, J, Qin, J, Zhang, H, Wang, W, Shen, Q, Mao, C, Zhang, Y. | | 登録日 | 2022-05-26 | | 公開日 | 2022-12-28 | | 最終更新日 | 2024-10-09 | | 実験手法 | ELECTRON MICROSCOPY (2.7 Å) | | 主引用文献 | Molecular basis for the activation of thyrotropin-releasing hormone receptor.
Cell Discov, 8, 2022
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7XUK
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7XUM
 | | Structure of ATP7B C983S/C985S/D1027A mutant with Cu+ in presence of ATOX1 | | 分子名称: | COPPER (II) ION, Copper-transporting ATPase 2 | | 著者 | Yang, G, Xu, L, Chang, S, Guo, J, Wu, Z. | | 登録日 | 2022-05-19 | | 公開日 | 2023-05-03 | | 最終更新日 | 2024-07-03 | | 実験手法 | ELECTRON MICROSCOPY (3.8 Å) | | 主引用文献 | Structures of the human Wilson disease copper transporter ATP7B.
Cell Rep, 42, 2023
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7XUN
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7XUO
 | | Structure of ATP7B C983S/C985S/D1027A mutant with cisplatin in presence of ATOX1 | | 分子名称: | Copper-transporting ATPase 2, PLATINUM (II) ION | | 著者 | Yang, G, Xu, L, Chang, S, Guo, J, Wu, Z. | | 登録日 | 2022-05-19 | | 公開日 | 2023-04-26 | | 最終更新日 | 2024-07-03 | | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | | 主引用文献 | Structures of the human Wilson disease copper transporter ATP7B.
Cell Rep, 42, 2023
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8X43
 | | human KCNQ2-CaM-Ebio1-S1 complex in the presence of PIP2 | | 分子名称: | Calmodulin-1, N-(4-azanyl-1,2-dihydroacenaphthylen-5-yl)-4-fluoranyl-benzamide, Potassium voltage-gated channel subfamily KQT member 2 | | 著者 | Ma, D, Guo, J. | | 登録日 | 2023-11-15 | | 公開日 | 2024-01-17 | | 最終更新日 | 2024-07-17 | | 実験手法 | ELECTRON MICROSCOPY (3 Å) | | 主引用文献 | A small-molecule activation mechanism that directly opens the KCNQ2 channel.
Nat.Chem.Biol., 20, 2024
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