7U1U
 
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3UIR
 | | Crystal structure of the plasmin-textilinin-1 complex | | Descriptor: | Plasmin light chain B, SULFATE ION, Textilinin-1 | | Authors: | Guddat, L.W, Millers, E.K, de jersey, J, Lavin, M.F, Masci, P.M. | | Deposit date: | 2011-11-05 | | Release date: | 2012-12-26 | | Last modified: | 2013-07-17 | | Method: | X-RAY DIFFRACTION (2.777 Å) | | Cite: | The structure of human microplasmin in complex with textilinin-1, an aprotinin-like inhibitor from the Australian brown snake.
Plos One, 8, 2013
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4IJQ
 | | Human hypoxanthine-guanine phosphoribosyltransferase in complex with [(2-((Guanine-9H-yl)methyl)propane-1,3-diyl)bis(oxy)]bis(methylene))diphosphonic acid | | Descriptor: | Hypoxanthine-guanine phosphoribosyltransferase, MAGNESIUM ION, SULFATE ION, ... | | Authors: | Guddat, L.W, Keough, D.T, Hockova, D. | | Deposit date: | 2012-12-22 | | Release date: | 2013-03-27 | | Last modified: | 2024-03-20 | | Method: | X-RAY DIFFRACTION (2.004 Å) | | Cite: | Acyclic nucleoside phosphonates containing a second phosphonate group are potent inhibitors of 6-oxopurine phosphoribosyltransferases and have antimalarial activity
J.Med.Chem., 56, 2013
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1G9T
 | | CRYSTAL STRUCTURE OF E.COLI HPRT-GMP COMPLEX | | Descriptor: | ANY 5'-MONOPHOSPHATE NUCLEOTIDE, GUANOSINE-5'-MONOPHOSPHATE, HYPOXANTHINE PHOSPHORIBOSYLTRANSFERASE | | Authors: | Guddat, L.W, Vos, S, Martin, J.L, keough, D.T, de Jersey, J. | | Deposit date: | 2000-11-28 | | Release date: | 2002-08-28 | | Last modified: | 2024-04-03 | | Method: | X-RAY DIFFRACTION (2.8 Å) | | Cite: | Crystal structures of free, IMP-, and GMP-bound Escherichia coli hypoxanthine phosphoribosyltransferase.
Protein Sci., 11, 2002
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1GRV
 | | Hypoxanthine Phosphoribosyltransferase from E. coli | | Descriptor: | HYPOXANTHINE PHOSPHORIBOSYLTRANSFERASE, MAGNESIUM ION | | Authors: | Guddat, L.W, Vos, S, Martin, J.L, Keough, D.T, De Jersey, J. | | Deposit date: | 2001-12-17 | | Release date: | 2002-12-13 | | Last modified: | 2023-12-13 | | Method: | X-RAY DIFFRACTION (2.9 Å) | | Cite: | Crystal Structures of Free, Imp-, and Gmp- Bound Escherichia Coli Hypoxanthine Phosphoribosyltransferase
Protein Sci., 11, 2002
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1G9S
 | | CRYSTAL STRUCTURE OF A COMPLEX BETWEEN E.COLI HPRT AND IMP | | Descriptor: | ANY 5'-MONOPHOSPHATE NUCLEOTIDE, HYPOXANTHINE PHOSPHORIBOSYLTRANSFERASE, INOSINIC ACID | | Authors: | Guddat, L.W, Vos, S, Martin, J.L, Keough, D.T, de Jersey, J. | | Deposit date: | 2000-11-27 | | Release date: | 2002-08-28 | | Last modified: | 2024-04-03 | | Method: | X-RAY DIFFRACTION (2.8 Å) | | Cite: | Crystal structures of free, IMP-, and GMP-bound Escherichia coli hypoxanthine phosphoribosyltransferase.
Protein Sci., 11, 2002
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1NOT
 | | THE 1.2 ANGSTROM STRUCTURE OF G1 ALPHA CONOTOXIN | | Descriptor: | GI ALPHA CONOTOXIN | | Authors: | Guddat, L.W, Shan, L, Martin, J.L, Edmundson, A.B, Gray, W.R. | | Deposit date: | 1996-05-02 | | Release date: | 1996-12-07 | | Last modified: | 2024-06-05 | | Method: | X-RAY DIFFRACTION (1.2 Å) | | Cite: | Three-dimensional structure of the alpha-conotoxin GI at 1.2 A resolution
Biochemistry, 35, 1996
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8TPY
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8TR1
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1UTE
 | | PIG PURPLE ACID PHOSPHATASE COMPLEXED WITH PHOSPHATE | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ISOPROPYL ALCOHOL, MU-OXO-DIIRON, ... | | Authors: | Guddat, L.W, Mcalpine, A, Hume, D, Hamilton, S, De Jersey, J, Martin, J.L. | | Deposit date: | 1999-01-18 | | Release date: | 1999-10-01 | | Last modified: | 2023-12-27 | | Method: | X-RAY DIFFRACTION (1.55 Å) | | Cite: | Crystal structure of mammalian purple acid phosphatase.
Structure Fold.Des., 7, 1999
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8TPV
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3GEP
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3GGJ
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3GGC
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3FR7
 | | ketol-acid reductoisomerase (KARI) in complex with Mg2+ | | Descriptor: | MAGNESIUM ION, Putative ketol-acid reductoisomerase (Os05g0573700 protein) | | Authors: | Guddat, L.W, Leung, E.W.W. | | Deposit date: | 2009-01-08 | | Release date: | 2009-04-14 | | Last modified: | 2023-09-06 | | Method: | X-RAY DIFFRACTION (1.55 Å) | | Cite: | Conformational changes in a plant ketol-acid reductoisomerase upon Mg(2+) and NADPH binding as revealed by two crystal structures
J.Mol.Biol., 389, 2009
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3E9Y
 | | Arabidopsis thaliana acetohydroxyacid synthase in complex with monosulfuron | | Descriptor: | 2-[(2E)-3-[(4-AMINO-2-METHYLPYRIMIDIN-5-YL)METHYL]-2-(1-HYDROXYETHYLIDENE)-4-METHYL-2,3-DIHYDRO-1,3-THIAZOL-5-YL]ETHYL TRIHYDROGEN DIPHOSPHATE, 2-[N-CYCLOHEXYLAMINO]ETHANE SULFONIC ACID, Acetolactate synthase, ... | | Authors: | Guddat, L.W, Duggleby, R.G, Wang, J.-G, Li, Z.-M. | | Deposit date: | 2008-08-24 | | Release date: | 2009-03-31 | | Last modified: | 2023-11-01 | | Method: | X-RAY DIFFRACTION (3 Å) | | Cite: | Crystal structures of two novel sulfonylurea herbicides in complex with Arabidopsis thaliana acetohydroxyacid synthase.
Febs J., 276, 2009
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3EA4
 | | Arabidopsis thaliana acetohydroxyacid synthase in complex with monosulfuron-ester | | Descriptor: | 2-[(2E)-3-[(4-AMINO-2-METHYLPYRIMIDIN-5-YL)METHYL]-2-(1-HYDROXYETHYLIDENE)-4-METHYL-2,3-DIHYDRO-1,3-THIAZOL-5-YL]ETHYL TRIHYDROGEN DIPHOSPHATE, 2-[N-CYCLOHEXYLAMINO]ETHANE SULFONIC ACID, Acetolactate synthase, ... | | Authors: | Guddat, L.W, Wang, J.-G, Li, Z.-M. | | Deposit date: | 2008-08-24 | | Release date: | 2009-03-31 | | Last modified: | 2023-11-01 | | Method: | X-RAY DIFFRACTION (2.8 Å) | | Cite: | Crystal structures of two novel sulfonylurea herbicides in complex with Arabidopsis thaliana acetohydroxyacid synthase.
Febs J., 276, 2009
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7RDU
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1ACV
 | | DSBA MUTANT H32S | | Descriptor: | DSBA | | Authors: | Guddat, L.W, Martin, J.L. | | Deposit date: | 1997-02-10 | | Release date: | 1997-10-15 | | Last modified: | 2023-08-02 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | Structural analysis of three His32 mutants of DsbA: support for an electrostatic role of His32 in DsbA stability.
Protein Sci., 6, 1997
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1AC1
 | | DSBA MUTANT H32L | | Descriptor: | DSBA | | Authors: | Guddat, L.W, Martin, J.L. | | Deposit date: | 1997-02-10 | | Release date: | 1997-10-15 | | Last modified: | 2023-08-02 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Structural analysis of three His32 mutants of DsbA: support for an electrostatic role of His32 in DsbA stability.
Protein Sci., 6, 1997
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6BD9
 | | Saccharomyces cerevisiae acetohydroxyacid synthase | | Descriptor: | Acetolactate synthase catalytic subunit, mitochondrial, FLAVIN-ADENINE DINUCLEOTIDE, ... | | Authors: | Guddat, L.W, Lonhienne, T. | | Deposit date: | 2017-10-22 | | Release date: | 2017-11-08 | | Last modified: | 2023-11-15 | | Method: | X-RAY DIFFRACTION (1.982 Å) | | Cite: | High resolution crystal structures of the acetohydroxyacid synthase-pyruvate complex provide new insights into its catalytic mechanism
Chemistryselect, 2017
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6BD3
 | | Saccharomyces cerevisiae acetohydroxyacid synthase | | Descriptor: | 2-ACETYL-THIAMINE DIPHOSPHATE, ACETATE ION, Acetolactate synthase catalytic subunit, ... | | Authors: | Guddat, L.W, Lonhienne, T. | | Deposit date: | 2017-10-21 | | Release date: | 2017-11-08 | | Last modified: | 2024-03-13 | | Method: | X-RAY DIFFRACTION (2.28 Å) | | Cite: | High resolution crystal structures of the acetohydroxyacid synthase-pyruvate complex provide new insights into its catalytic mechanism
Chemistryselect, 2017
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6BO7
 | | Crystal structure of Plasmodium vivax hypoxanthine guanine phosphoribosyltransferase in complex with [3R,4R]-4-guanin-9-yl-3-((S)-2-hydroxy-2-phosphonoethyl)oxy-1-N-(phosphonopropionyl)pyrrolidine | | Descriptor: | Hypoxanthine phosphoribosyltransferase, MAGNESIUM ION, [3-[(3~{R},4~{R})-3-(2-azanyl-6-oxidanylidene-1~{H}-purin-9-yl)-4-[(2~{S})-2-oxidanyl-2-phosphono-ethoxy]pyrrolidin-1-y l]-3-oxidanylidene-propyl]phosphonic acid | | Authors: | Guddat, L.W, Keough, D.T, Rejman, D. | | Deposit date: | 2017-11-18 | | Release date: | 2017-12-13 | | Last modified: | 2024-03-13 | | Method: | X-RAY DIFFRACTION (2.856 Å) | | Cite: | Design of Plasmodium vivax Hypoxanthine-Guanine Phosphoribosyltransferase Inhibitors as Potential Antimalarial Therapeutics.
ACS Chem. Biol., 13, 2018
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5IMS
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1CGS
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