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PDB: 86 results

2DGK
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BU of 2dgk by Molmil
Crystal structure of an N-terminal deletion mutant of Escherichia coli GadB in an autoinhibited state (aldamine)
Descriptor: 1,2-ETHANEDIOL, Glutamate decarboxylase beta, PYRIDOXAL-5'-PHOSPHATE, ...
Authors:Gruetter, M.G, Capitani, G, Gut, H.
Deposit date:2006-03-14
Release date:2006-06-20
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Escherichia coli acid resistance: pH-sensing, activation by chloride and autoinhibition in GadB
Embo J., 25, 2006
2DGL
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BU of 2dgl by Molmil
Crystal structure of Escherichia coli GadB in complex with bromide
Descriptor: ACETIC ACID, BROMIDE ION, Glutamate decarboxylase beta, ...
Authors:Gruetter, M.G, Capitani, G, Gut, H.
Deposit date:2006-03-14
Release date:2006-06-20
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (3.15 Å)
Cite:Escherichia coli acid resistance: pH-sensing, activation by chloride and autoinhibition in GadB
Embo J., 25, 2006
2DGM
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BU of 2dgm by Molmil
Crystal structure of Escherichia coli GadB in complex with iodide
Descriptor: ACETIC ACID, DI(HYDROXYETHYL)ETHER, FORMIC ACID, ...
Authors:Gruetter, M.G, Capitani, G, Gut, H.
Deposit date:2006-03-14
Release date:2006-06-20
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Escherichia coli acid resistance: pH-sensing, activation by chloride and autoinhibition in GadB
Embo J., 25, 2006
1TFG
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BU of 1tfg by Molmil
AN UNUSUAL FEATURE REVEALED BY THE CRYSTAL STRUCTURE AT 2.2 ANGSTROMS RESOLUTION OF HUMAN TRANSFORMING GROWTH FACTOR-BETA2
Descriptor: TRANSFORMING GROWTH FACTOR, BETA 2
Authors:Gruetter, M, Schlunegger, M.
Deposit date:1992-11-17
Release date:1993-10-31
Last modified:2019-08-14
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:An unusual feature revealed by the crystal structure at 2.2 A resolution of human transforming growth factor-beta 2.
Nature, 358, 1992
1RNE
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BU of 1rne by Molmil
THE CRYSTAL STRUCTURE OF RECOMBINANT GLYCOSYLATED HUMAN RENIN ALONE AND IN COMPLEX WITH A TRANSITION STATE ANALOG INHIBITOR
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, RENIN, [[[3-(2-METHYL-PROPANE-2-SULFONYL)-1-BENZENYL]-2-PROPYL]-CARBONYL-HISTIDYL]-AMINO-[CYCLOHEXYLMETHYL]-[2-HYDROXY-4-ISOPROPYL]-PENTAN-5-OIC ACID BUTYLAMIDE
Authors:Gruetter, M.G, Rahuel, J, Priestle, J.P.
Deposit date:1991-12-12
Release date:1993-10-31
Last modified:2024-10-30
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:The crystal structures of recombinant glycosylated human renin alone and in complex with a transition state analog inhibitor.
J.Struct.Biol., 107, 1991
1SBN
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BU of 1sbn by Molmil
REFINED CRYSTAL STRUCTURES OF SUBTILISIN NOVO IN COMPLEX WITH WILD-TYPE AND TWO MUTANT EGLINS. COMPARISON WITH OTHER SERINE PROTEINASE INHIBITOR COMPLEXES
Descriptor: CALCIUM ION, EGLIN C, SUBTILISIN NOVO BPN'
Authors:Gruetter, M.G, Heinz, D.W, Priestle, J.P.
Deposit date:1991-12-20
Release date:1994-01-31
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Refined crystal structures of subtilisin novo in complex with wild-type and two mutant eglins. Comparison with other serine proteinase inhibitor complexes.
J.Mol.Biol., 217, 1991
1SIB
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BU of 1sib by Molmil
REFINED CRYSTAL STRUCTURES OF SUBTILISIN NOVO IN COMPLEX WITH WILD-TYPE AND TWO MUTANT EGLINS. COMPARISON WITH OTHER SERINE PROTEINASE INHIBITOR COMPLEXES
Descriptor: CALCIUM ION, EGLIN C, SUBTILISIN NOVO BPN'
Authors:Gruetter, M.G, Heinz, D.W, Priestle, J.P.
Deposit date:1993-08-02
Release date:1993-10-31
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Refined crystal structures of subtilisin novo in complex with wild-type and two mutant eglins. Comparison with other serine proteinase inhibitor complexes.
J.Mol.Biol., 217, 1991
2FBE
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BU of 2fbe by Molmil
Crystal Structure of the PRYSPRY-domain
Descriptor: PREDICTED: similar to ret finger protein-like 1
Authors:Gruetter, C, Briand, C, Capitani, G, Mittl, P.R, Gruetter, M.G.
Deposit date:2005-12-09
Release date:2006-01-10
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.52 Å)
Cite:Structure of the PRYSPRY-domain: Implications for autoinflammatory diseases
Febs Lett., 580, 2006
5FIN
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BU of 5fin by Molmil
DARPins as a new tool for experimental phasing in protein crystallography
Descriptor: MERCURY (II) ION, NI3C DARPIN MUTANT5 HG-SITE N1
Authors:Batyuk, A, Honegger, A, Andres, F, Briand, C, Gruetter, M, Plueckthun, A.
Deposit date:2015-09-30
Release date:2016-11-16
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (2.34 Å)
Cite:Darpins as a New Tool for Experimental Phasing in Protein Crystallography
To be Published
3EO0
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BU of 3eo0 by Molmil
Structure of the Transforming Growth Factor-Beta Neutralizing Antibody GC-1008
Descriptor: GC-1008 Fab Heavy Chain, GC-1008 Fab Light Chain, GLYCEROL
Authors:Gruetter, C, Gruetter, M.G.
Deposit date:2008-09-26
Release date:2008-12-02
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:A cytokine-neutralizing antibody as a structural mimetic of 2 receptor interactions
Proc.Natl.Acad.Sci.Usa, 105, 2008
3EO1
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BU of 3eo1 by Molmil
Structure of the Fab Fragment of GC-1008 in Complex with Transforming Growth Factor-Beta 3
Descriptor: GC-1008 Fab Heavy Chain, GC-1008 Fab Light Chain, Transforming growth factor beta-3
Authors:Gruetter, C, Gruetter, M.G.
Deposit date:2008-09-26
Release date:2008-12-02
Last modified:2024-10-09
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:A cytokine-neutralizing antibody as a structural mimetic of 2 receptor interactions
Proc.Natl.Acad.Sci.Usa, 105, 2008
1VRS
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BU of 1vrs by Molmil
Crystal structure of the disulfide-linked complex between the N-terminal and C-terminal domain of the electron transfer catalyst DsbD
Descriptor: Thiol:disulfide interchange protein dsbD
Authors:Rozhkova, A, Stirnimann, C.U, Frei, P, Grauschopf, U, Brunisholz, R, Gruetter, M.G, Capitani, G, Glockshuber, R.
Deposit date:2005-06-17
Release date:2005-07-12
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (2.85 Å)
Cite:Structural basis and kinetics of inter- and intramolecular disulfide exchange in the redox catalyst DsbD
Embo J., 23, 2004
1Z5Y
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BU of 1z5y by Molmil
Crystal Structure Of The Disulfide-Linked Complex Between The N-Terminal Domain Of The Electron Transfer Catalyst DsbD and The Cytochrome c Biogenesis Protein CcmG
Descriptor: 1,2-ETHANEDIOL, CHLORIDE ION, Thiol:disulfide interchange protein dsbD, ...
Authors:Stirnimann, C.U, Rozhkova, A, Grauschopf, U, Gruetter, M.G, Glockshuber, R, Capitani, G.
Deposit date:2005-03-21
Release date:2005-07-19
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (1.94 Å)
Cite:Structural Basis and Kinetics of DsbD-Dependent Cytochrome c Maturation
STRUCTURE, 13, 2005
5FIO
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BU of 5fio by Molmil
DARPins as a new tool for experimental phasing in protein crystallography
Descriptor: MALTOSE-BINDING PERIPLASMIC PROTEIN, MERCURY (II) ION, NI3C DARPIN MUTANT5 HG-SITE N1
Authors:Batyuk, A, Honegger, A, Andres, F, Briand, C, Gruetter, M, Plueckthun, A.
Deposit date:2015-09-30
Release date:2016-11-16
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Darpins as a New Tool for Experimental Phasing in Protein Crystallography
To be Published
2WL1
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BU of 2wl1 by Molmil
Pyrin PrySpry domain
Descriptor: 1,2-ETHANEDIOL, PYRIN, THIOCYANATE ION
Authors:Weinert, C, Mittl, P.R, Gruetter, M.G.
Deposit date:2009-06-19
Release date:2009-10-20
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (1.35 Å)
Cite:The Crystal Structure of Human Pyrin B30.2 Domain: Implications for Mutations Associated with Familial Mediterranean Fever.
J.Mol.Biol., 394, 2009
1MJ0
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BU of 1mj0 by Molmil
SANK E3_5: an artificial Ankyrin repeat protein
Descriptor: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, SANK E3_5 Protein, SULFATE ION
Authors:Kohl, A, Binz, H.K, Forrer, P, Stumpp, M.T, Plueckthun, A, Gruetter, M.G.
Deposit date:2002-08-26
Release date:2003-01-21
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.031 Å)
Cite:Designed to be stable: Crystal structure of a consensus ankyrin repeat protein
Proc.Natl.Acad.Sci.USA, 100, 2003
1M7Y
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BU of 1m7y by Molmil
Crystal structure of apple ACC synthase in complex with L-aminoethoxyvinylglycine
Descriptor: (2E,3E)-4-(2-aminoethoxy)-2-[({3-hydroxy-2-methyl-5-[(phosphonooxy)methyl]pyridin-4-yl}methyl)imino]but-3-enoic acid, (4R)-2-METHYLPENTANE-2,4-DIOL, 1-aminocyclopropane-1-carboxylate synthase
Authors:Capitani, G, McCarthy, D, Gut, H, Gruetter, M.G, Kirsch, J.F.
Deposit date:2002-07-23
Release date:2002-12-23
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Apple 1-Aminocyclopropane-1-carboxylate Synthase in Complex with the Inhibitor L-Aminoethoxyvinylglycine
J.Biol.Chem., 277, 2002
2I1B
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BU of 2i1b by Molmil
CRYSTALLOGRAPHIC REFINEMENT OF INTERLEUKIN-1 BETA AT 2.0 ANGSTROMS RESOLUTION
Descriptor: INTERLEUKIN-1 BETA
Authors:Priestle, J.P, Schaer, H.-P, Gruetter, M.G.
Deposit date:1990-01-02
Release date:1990-04-15
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystallographic refinement of interleukin 1 beta at 2.0 A resolution.
Proc.Natl.Acad.Sci.USA, 86, 1989
1HIH
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BU of 1hih by Molmil
COMPARATIVE ANALYSIS OF THE X-RAY STRUCTURES OF HIV-1 AND HIV-2 PROTEASES IN COMPLEX WITH CGP 53820, A NOVEL PSEUDOSYMMETRIC INHIBITOR
Descriptor: ACETYL-NH-VAL-CYCLOHEXYL-CH2[NCH2CHOH]CH2-BENZYL-VAL-NH-ACETYL, BETA-MERCAPTOETHANOL, HIV-1 PROTEASE
Authors:Priestle, J.P, Gruetter, M.G.
Deposit date:1995-03-31
Release date:1995-07-10
Last modified:2018-04-18
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Comparative analysis of the X-ray structures of HIV-1 and HIV-2 proteases in complex with CGP 53820, a novel pseudosymmetric inhibitor.
Structure, 3, 1995
2AXI
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BU of 2axi by Molmil
HDM2 in complex with a beta-hairpin
Descriptor: 3[N-MORPHOLINO]PROPANE SULFONIC ACID, SULFATE ION, Ubiquitin-protein ligase E3 Mdm2, ...
Authors:Mittl, P.R.E, Fasan, R, Robinson, J, Gruetter, M.G.
Deposit date:2005-09-05
Release date:2006-03-21
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Structure-Activity Studies in a Family of beta-Hairpin Protein Epitope Mimetic Inhibitors of the p53-HDM2 Protein-Protein Interaction.
Chembiochem, 7, 2006
1HII
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BU of 1hii by Molmil
COMPARATIVE ANALYSIS OF THE X-RAY STRUCTURES OF HIV-1 AND HIV-2 PROTEASES IN COMPLEX WITH CGP 53820, A NOVEL PSEUDOSYMMETRIC INHIBITOR
Descriptor: ACETYL-NH-VAL-CYCLOHEXYL-CH2[NCH2CHOH]CH2-BENZYL-VAL-NH-ACETYL, HIV-2 PROTEASE, SULFATE ION
Authors:Priestle, J.P, Gruetter, M.G.
Deposit date:1995-03-31
Release date:1995-07-10
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Comparative analysis of the X-ray structures of HIV-1 and HIV-2 proteases in complex with CGP 53820, a novel pseudosymmetric inhibitor.
Structure, 3, 1995
1HIA
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BU of 1hia by Molmil
KALLIKREIN COMPLEXED WITH HIRUSTASIN
Descriptor: HIRUSTASIN, KALLIKREIN
Authors:Mittl, P, Di Marco, S, Gruetter, M.
Deposit date:1996-12-12
Release date:1997-12-24
Last modified:2024-10-23
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:A new structural class of serine protease inhibitors revealed by the structure of the hirustasin-kallikrein complex.
Structure, 5, 1997
2V50
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BU of 2v50 by Molmil
The Missing Part of the Bacterial MexAB-OprM System: Structural determination of the Multidrug Exporter MexB
Descriptor: DODECYL-BETA-D-MALTOSIDE, MULTIDRUG RESISTANCE PROTEIN MEXB
Authors:Sennhauser, G, Bukowska, M.A, Gruetter, M.G.
Deposit date:2008-10-01
Release date:2009-05-19
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (3 Å)
Cite:Crystal Structure of the Multidrug Exporter Mexb from Pseudomonas Aeruginosa.
J.Mol.Biol., 389, 2009
4CDL
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BU of 4cdl by Molmil
Crystal Structure of Retro-aldolase RA110.4-6 Complexed with Inhibitor 1-(6-methoxy-2-naphthalenyl)-1,3-butanedione
Descriptor: (2E)-1-(6-methoxynaphthalen-2-yl)but-2-en-1-one, STEROID DELTA-ISOMERASE
Authors:Pinkas, D.M, Studer, S, Obexer, R, Giger, L, Gruetter, M.G, Baker, D, Hilvert, D.
Deposit date:2013-11-01
Release date:2014-11-12
Last modified:2024-10-23
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Active Site Plasticity of a Computationally Designed Retro-Aldolase Enzyme
To be Published
2RKO
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BU of 2rko by Molmil
Crystal Structure of the Vps4p-dimer
Descriptor: Vacuolar protein sorting-associated protein 4
Authors:Hartmann, C, Gruetter, M.G.
Deposit date:2007-10-17
Release date:2008-02-26
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (3.35 Å)
Cite:Vacuolar protein sorting: two different functional states of the AAA-ATPase Vps4p
J.Mol.Biol., 377, 2008

 

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