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PDB: 45 results

2GCD
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TAO2 kinase domain-staurosporine structure
Descriptor: STAUROSPORINE, Serine/threonine-protein kinase TAO2
Authors:Zhou, T, Sun, L, Gao, Y, Earnest, S, Cobb, M.H, Goldsmith, E.J.
Deposit date:2006-03-14
Release date:2006-09-05
Last modified:2017-10-18
Method:X-RAY DIFFRACTION (2.55 Å)
Cite:Crystal structure of the MAP3K TAO2 kinase domain bound by an inhibitor staurosporine.
Acta Biochim.Biophys.Sinica, 38, 2006
3N29
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Crystal structure of carboxynorspermidine decarboxylase complexed with Norspermidine from Campylobacter jejuni
Descriptor: Carboxynorspermidine decarboxylase, GLYCEROL, N-(3-aminopropyl)propane-1,3-diamine, ...
Authors:Deng, X, Lee, J, Michael, A.J, Tomchick, D.R, Goldsmith, E.J, Phillips, M.A.
Deposit date:2010-05-17
Release date:2010-06-09
Last modified:2012-02-22
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Evolution of substrate specificity within a diverse family of beta/alpha-barrel-fold basic amino acid decarboxylases: X-ray structure determination of enzymes with specificity for L-arginine and carboxynorspermidine.
J.Biol.Chem., 285, 2010
1LEW
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CRYSTAL STRUCTURE OF MAP KINASE P38 COMPLEXED TO THE DOCKING SITE ON ITS NUCLEAR SUBSTRATE MEF2A
Descriptor: Mitogen-activated protein kinase 14, Myocyte-specific enhancer factor 2A
Authors:Chang, C.-I, Xu, B.-E, Akella, R, Cobb, M.H, Goldsmith, E.J.
Deposit date:2002-04-10
Release date:2002-07-10
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Crystal structures of MAP kinase p38 complexed to the docking sites on its nuclear substrate MEF2A and activator MKK3b.
Mol.Cell, 9, 2002
1LLQ
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Crystal Structure of Malic Enzyme from Ascaris suum Complexed with Nicotinamide Adenine Dinucleotide
Descriptor: NAD-dependent malic enzyme, NICOTINAMIDE-ADENINE-DINUCLEOTIDE
Authors:Coleman, D.E, Jagannatha, G.S, Goldsmith, E.J, Cook, P.F, Harris, B.G.
Deposit date:2002-04-29
Release date:2002-05-08
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Crystal structure of the malic enzyme from Ascaris suum complexed with nicotinamide adenine dinucleotide at 2.3 A resolution.
Biochemistry, 41, 2002
1LEZ
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CRYSTAL STRUCTURE OF MAP KINASE P38 COMPLEXED TO THE DOCKING SITE ON ITS ACTIVATOR MKK3B
Descriptor: MAP kinase kinase 3b, MITOGEN-ACTIVATED PROTEIN KINASE 14
Authors:Chang, C.-I, Xu, B.-E, Akella, R, Cobb, M.H, Goldsmith, E.J.
Deposit date:2002-04-10
Release date:2002-07-10
Last modified:2021-10-27
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Crystal structures of MAP kinase p38 complexed to the docking sites on its nuclear substrate MEF2A and activator MKK3b.
Mol.Cell, 9, 2002
2PLJ
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Crystal structure of lysine/ornithine decarboxylase complexed with putrescine from Vibrio vulnificus
Descriptor: (4-{[(4-AMINOBUTYL)AMINO]METHYL}-5-HYDROXY-6-METHYLPYRIDIN-3-YL)METHYL DIHYDROGEN PHOSPHATE, MAGNESIUM ION, lysine/ornithine decarboxylase
Authors:Lee, J, Goldsmith, E.J, Phillips, M.A.
Deposit date:2007-04-19
Release date:2007-07-10
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Phylogenetic diversity and the structural basis of substrate specificity in the beta/alpha-barrel fold basic amino acid decarboxylases.
J.Biol.Chem., 282, 2007
2GPH
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Docking motif interactions in the MAP kinase ERK2
Descriptor: Mitogen-activated protein kinase 1, Tyrosine-protein phosphatase non-receptor type 7
Authors:Zhou, T, Sun, L, Humphreys, J, Goldsmith, E.J.
Deposit date:2006-04-17
Release date:2006-07-04
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Docking Interactions Induce Exposure of Activation Loop in the MAP Kinase ERK2.
Structure, 14, 2006
1U5Q
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Crystal Structure of the TAO2 Kinase Domain: Activation and Specifity of a Ste20p MAP3K
Descriptor: CALCIUM ION, serine/threonine protein kinase TAO2
Authors:Zhou, T, Raman, M, Gao, Y, Earnest, S, Chen, Z, Machius, M, Cobb, M.H, Goldsmith, E.J.
Deposit date:2004-07-28
Release date:2004-10-12
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Crystal Structure of the TAO2 Kinase Domain; Activation and Specificity of a Ste20p MAP3K.
STRUCTURE, 12, 2004
1U5R
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Crystal Structure of the TAO2 Kinase Domain: Activation and Specifity of a Ste20p MAP3K
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, CALCIUM ION, MAGNESIUM ION, ...
Authors:Zhou, T, Raman, M, Gao, Y, Earnest, S, Chen, Z, Machius, M, Cobb, M.H, Goldsmith, E.J.
Deposit date:2004-07-28
Release date:2004-10-12
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Crystal Structure of the TAO2 Kinase Domain; Activation and Specificity of a Ste20p MAP3K.
Structure, 12, 2004
1SZR
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A Dimer interface mutant of ornithine decarboxylase reveals structure of gem diamine intermediate
Descriptor: N-GLYCINE-[3-HYDROXY-2-METHYL-5-PHOSPHONOOXYMETHYL-PYRIDIN-4-YL-METHANE], N~2~-({3-HYDROXY-2-METHYL-5-[(PHOSPHONOOXY)METHYL]PYRIDIN-4-YL}METHYL)-D-ORNITHINE, Ornithine decarboxylase, ...
Authors:Jackson, L.K, Baldwin, J, Goldsmith, E.J, Phillips, M.A.
Deposit date:2004-04-06
Release date:2004-10-26
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:Multiple active site conformations revealed by distant site mutation in ornithine decarboxylase
Biochemistry, 43, 2004
3P4K
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The third conformation of p38a MAP kinase observed in phosphorylated p38a and in solution
Descriptor: MAP kinase 14, Mitogen-activated protein kinase 14
Authors:Akella, R, Min, X, Wu, Q, Gardner, K.H, Goldsmith, E.J.
Deposit date:2010-10-06
Release date:2011-01-05
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.304 Å)
Cite:The third conformation of p38a MAP kinase observed in phosphorylated p38a and in solution
Structure, 18, 2010
2LRU
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Solution Structure of the WNK1 Autoinhibitory Domain
Descriptor: Serine/threonine-protein kinase WNK1
Authors:Moon, T.M, Correa, F, Gardner, K.H, Goldsmith, E.J.
Deposit date:2012-04-13
Release date:2012-05-23
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:Solution Structure of the WNK1 Autoinhibitory Domain, a WNK-Specific PF2 Domain.
J.Mol.Biol., 425, 2013
1K9O
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CRYSTAL STRUCTURE OF MICHAELIS SERPIN-TRYPSIN COMPLEX
Descriptor: ALASERPIN, TRYPSIN II ANIONIC
Authors:Ye, S, Cech, A.L, Belmares, R, Bergstrom, R.C, Tong, Y, Corey, D.R, Kanost, M.R, Goldsmith, E.J.
Deposit date:2001-10-29
Release date:2001-11-21
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:The structure of a Michaelis serpin-protease complex.
Nat.Struct.Biol., 8, 2001
1SEK
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THE STRUCTURE OF ACTIVE SERPIN K FROM MANDUCA SEXTA AND A MODEL FOR SERPIN-PROTEASE COMPLEX FORMATION
Descriptor: SERPIN K
Authors:Li, J, Wang, Z, Canagarajah, B, Jiang, H, Kanost, M, Goldsmith, E.J.
Deposit date:1998-03-06
Release date:1999-03-23
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:The structure of active serpin 1K from Manduca sexta.
Structure Fold.Des., 7, 1999
1NJJ
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Crystal structure determination of T. brucei ornithine decarboxylase bound to D-ornithine and to G418
Descriptor: GENETICIN, N~2~-({3-HYDROXY-2-METHYL-5-[(PHOSPHONOOXY)METHYL]PYRIDIN-4-YL}METHYL)-D-ORNITHINE, ornithine decarboxylase
Authors:Jackson, L.K, Goldsmith, E.J, Phillips, M.A.
Deposit date:2002-12-31
Release date:2003-08-26
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (2.45 Å)
Cite:X-ray Structure Determination of Trypanosoma brucei Ornithine Decarboxylase Bound to D-Ornithine and to G418: INSIGHTS INTO SUBSTRATE BINDING AND ODC CONFORMATIONAL FLEXIBILITY.
J.Biol.Chem., 278, 2003
1QU4
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CRYSTAL STRUCTURE OF TRYPANOSOMA BRUCEI ORNITHINE DECARBOXYLASE
Descriptor: ORNITHINE DECARBOXYLASE, PYRIDOXAL-5'-PHOSPHATE
Authors:Grishin, N.V, Osterman, A.L, Brooks, H.B, Phillips, M.A, Goldsmith, E.J.
Deposit date:1999-07-06
Release date:1999-11-17
Last modified:2021-11-03
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:X-ray structure of ornithine decarboxylase from Trypanosoma brucei: the native structure and the structure in complex with alpha-difluoromethylornithine.
Biochemistry, 38, 1999
1A9U
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THE COMPLEX STRUCTURE OF THE MAP KINASE P38/SB203580
Descriptor: 4-[5-(4-FLUORO-PHENYL)-2-(4-METHANESULFINYL-PHENYL)-3H-IMIDAZOL-4-YL]-PYRIDINE, MAP KINASE P38
Authors:Wang, Z, Canagarajah, B, Boehm, J.C, Kassis, S, Cobb, M.H, Young, P.R, Abdel-Meguid, S, Adams, J.L, Goldsmith, E.J.
Deposit date:1998-04-10
Release date:1999-04-20
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structural basis of inhibitor selectivity in MAP kinases.
Structure, 6, 1998
1BMK
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THE COMPLEX STRUCTURE OF THE MAP KINASE P38/SB218655
Descriptor: 4-(FLUOROPHENYL)-1-CYCLOPROPYLMETHYL-5-(2-AMINO-4-PYRIMIDINYL)IMIDAZOLE, PROTEIN (MAP KINASE P38)
Authors:Wang, Z, Canagarajah, B, Boehm, J.C, Kassis, S, Cobb, M.H, Young, P.R, Abdel-Meguid, S, Adams, J.L, Goldsmith, E.J.
Deposit date:1998-07-23
Release date:1999-07-23
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structural basis of inhibitor selectivity in MAP kinases.
Structure, 6, 1998
1BL6
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THE COMPLEX STRUCTURE OF THE MAP KINASE P38/SB216995
Descriptor: 4-(4-FLUOROPHENYL)-1-CYCLOROPROPYLMETHYL-5-(4-PYRIDYL)-IMIDAZOLE, PROTEIN (MAP KINASE P38)
Authors:Wang, Z, Canagarajah, B.J, Boehm, J.C, Kassis, S, Cobb, M.H, Young, P.R, Abdel-Meguid, S, Adams, J.L, Goldsmith, E.J.
Deposit date:1998-07-11
Release date:1999-07-26
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structural basis of inhibitor selectivity in MAP kinases.
Structure, 6, 1998
1BL7
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THE COMPLEX STRUCTURE OF THE MAP KINASE P38/SB220025
Descriptor: 4-(4-FLUOROPHENYL)-1-(4-PIPERIDINYL)-5-(2-AMINO-4-PYRIMIDINYL)-IMIDAZOLE, PROTEIN (MAP KINASE P38)
Authors:Wang, Z, Canagarajah, B.J, Boehm, J.C, Kassis, S, Cobb, M.H, Young, P.R, Abdel-Meguid, S, Adams, J.L, Goldsmith, E.J.
Deposit date:1998-07-23
Release date:1999-07-26
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structural basis of inhibitor selectivity in MAP kinases.
Structure, 6, 1998
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