6ZVQ
| Complex between SMAD2 MH2 domain and peptide from Ski corepressor | Descriptor: | D(-)-TARTARIC ACID, GLYCEROL, Mothers against decapentaplegic homolog 2, ... | Authors: | Purkiss, A.G, Kjaer, S, George, R, Hill, C.S. | Deposit date: | 2020-07-27 | Release date: | 2021-06-09 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (2.03 Å) | Cite: | Mutations in SKI in Shprintzen-Goldberg syndrome lead to attenuated TGF-beta responses through SKI stabilization. Elife, 10, 2021
|
|
1NAV
| Thyroid Receptor Alpha in complex with an agonist selective for Thyroid Receptor Beta1 | Descriptor: | SULFATE ION, hormone receptor alpha 1, THRA1, ... | Authors: | Ye, L, Li, Y.L, Mellstrom, K, Mellin, C, Bladh, L.G, Koehler, K, Garg, N, Garcia Collazo, A.M, Litten, C, Husman, B, Persson, K, Ljunggren, J, Grover, G, Sleph, P.G, George, R, Malm, J. | Deposit date: | 2002-11-29 | Release date: | 2003-06-17 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Thyroid receptor ligands. 1. Agonist ligands selective for the thyroid receptor beta1. J.Med.Chem., 46, 2003
|
|
1NAX
| Thyroid receptor beta1 in complex with a beta-selective ligand | Descriptor: | Thyroid hormone receptor beta-1, {3,5-DICHLORO-4-[4-HYDROXY-3-(PROPAN-2-YL)PHENOXY]PHENYL}ACETIC ACID | Authors: | Ye, L, Li, Y.L, Mellstrom, K, Mellin, C, Bladh, L.G, Koehler, K, Garg, N, Garcia Collazo, A.M, Litten, C, Husman, B, Persson, K, Ljunggren, J, Grover, G, Sleph, P.G, George, R, Malm, J. | Deposit date: | 2002-11-29 | Release date: | 2003-06-17 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Thyroid receptor ligands. 1. Agonist ligands selective for the thyroid receptor beta1. J.Med.Chem., 46, 2003
|
|
1Q31
| Crystal Structure of the Tobacco Etch Virus Protease C151A mutant | Descriptor: | BETA-MERCAPTOETHANOL, Nuclear inclusion protein A | Authors: | Nunn, C.M, Djordjevic, S, George, R.R, Urquhart, G.T, Chao, L.H, Tsuchiya, Y. | Deposit date: | 2003-07-28 | Release date: | 2004-11-02 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Crystal structure of tobacco etch virus protease shows the protein C terminus bound within the active site. J.Mol.Biol., 350, 2005
|
|
4UX8
| RET recognition of GDNF-GFRalpha1 ligand by a composite binding site promotes membrane-proximal self-association | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, GDNF FAMILY RECEPTOR ALPHA-1, ... | Authors: | Goodman, K, Kjaer, S, Beuron, F, Knowles, P, Nawrotek, A, Burns, E, Purkiss, A, George, R, Santoro, M, Morris, E.P, McDonald, N.Q. | Deposit date: | 2014-08-19 | Release date: | 2014-10-01 | Last modified: | 2020-07-29 | Method: | ELECTRON MICROSCOPY (24 Å) | Cite: | Ret Recognition of Gdnf-Gfralpha1 Ligand by a Composite Binding Site Promotes Membrane-Proximal Self-Association. Cell Rep., 8, 2014
|
|
6YRF
| Vip3Bc1 tetramer | Descriptor: | Vegetative insecticidal protein | Authors: | Thompson, R.F, Byrne, M.J, Iadanza, M.I, Arribas Perez, M, Maskell, D.P, George, R.M, Hesketh, E.L, Beales, P.A, Zack, M.D, Berry, C. | Deposit date: | 2020-04-20 | Release date: | 2021-03-17 | Last modified: | 2021-05-26 | Method: | ELECTRON MICROSCOPY (3.9 Å) | Cite: | Cryo-EM structures of an insecticidal Bt toxin reveal its mechanism of action on the membrane. Nat Commun, 12, 2021
|
|
8QMF
| Transketolase from Vibrio vulnificus in complex with thiamin pyrophosphate | Descriptor: | 1,2-ETHANEDIOL, MAGNESIUM ION, NICKEL (II) ION, ... | Authors: | Ballut, L, Georges, R.N, Octobre, G, Charmantray, F, Doumeche, B. | Deposit date: | 2023-09-22 | Release date: | 2024-02-07 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Structural determination and kinetic analysis of the transketolase from Vibrio vulnificus reveal unexpected cooperative behavior. Protein Sci., 33, 2024
|
|
6WG7
| Coordinates of NanR dimer fitted in Hexameric NanR-DNA hetero-complex cryo-EM map | Descriptor: | DNA (35-MER), HTH-type transcriptional repressor NanR | Authors: | Hariprasad, V, Horne, C, Santosh, P, Amy, H, Emre, B, Rachel, N, Michael, G, Georg, R, Borries, D, Renwick, D. | Deposit date: | 2020-04-05 | Release date: | 2021-03-10 | Last modified: | 2024-03-06 | Method: | ELECTRON MICROSCOPY (8.3 Å) | Cite: | Mechanism of NanR gene repression and allosteric induction of bacterial sialic acid metabolism. Nat Commun, 12, 2021
|
|
6WFQ
| NanR dimer-DNA hetero-complex | Descriptor: | DNA (5'-D(P*GP*GP*TP*AP*TP*AP*AP*CP*AP*GP*GP*TP*AP*TP*A)-3'), DNA (5'-D(P*TP*AP*TP*AP*CP*CP*TP*GP*TP*TP*AP*TP*AP*CP*C)-3'), HTH-type transcriptional repressor NanR | Authors: | Hariprasad, V, Horne, C, Santosh, P, Amy, H, Emre, B, Rachel, N, Michael, G, Georg, R, Borries, D, Renwick, D. | Deposit date: | 2020-04-03 | Release date: | 2021-03-10 | Last modified: | 2024-03-06 | Method: | ELECTRON MICROSCOPY (3.9 Å) | Cite: | Mechanism of NanR gene repression and allosteric induction of bacterial sialic acid metabolism. Nat Commun, 12, 2021
|
|