6ZVQ

Complex between SMAD2 MH2 domain and peptide from Ski corepressor

Summary for 6ZVQ

• Entry DOI: 10.2210/pdb6zvq/pdb
• Descriptor: Mothers against decapentaplegic homolog 2, Ski oncogene, SULFATE ION, ... (6 entities in total)
• Functional Keywords: phosphoserine, signal transduction, transcription modulation, transcription
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 2
• Total formula weight: 30766.10

Authors

Purkiss, A.G.,Kjaer, S.,George, R.,Hill, C.S. (deposition date: 2020-07-27, release date: 2021-06-09, Last modification date: 2024-01-31)

• Primary citation: Gori, I.,George, R.,Purkiss, A.G.,Strohbuecker, S.,Randall, R.A.,Ogrodowicz, R.,Carmignac, V.,Faivre, L.,Joshi, D.,Kjaer, S.,Hill, C.S.; Mutations in SKI in Shprintzen-Goldberg syndrome lead to attenuated TGF-beta responses through SKI stabilization.; Elife, 10:-, 2021; PubMed: 33416497; DOI: 10.7554/eLife.63545

Experimental method

X-RAY DIFFRACTION (2.03 Å)