6WFQ

NanR dimer-DNA hetero-complex

Summary for 6WFQ

• Entry DOI: 10.2210/pdb6wfq/pdb
• EMDB information: 21652
• Descriptor: HTH-type transcriptional repressor NanR, DNA (5'-D(P*GP*GP*TP*AP*TP*AP*AP*CP*AP*GP*GP*TP*AP*TP*A)-3'), DNA (5'-D(P*TP*AP*TP*AP*CP*CP*TP*GP*TP*TP*AP*TP*AP*CP*C)-3') (3 entities in total)
• Functional Keywords: nanr dimer-dna hetero-complex, transcriptional regulator, gntr superfamily, sialic acid, neu5ac, cooperativity., gene regulation
• Biological source: Escherichia coli; More
• Total number of polymer chains: 4
• Total formula weight: 68308.73

Authors

Hariprasad, V.,Horne, C.,Santosh, P.,Amy, H.,Emre, B.,Rachel, N.,Michael, G.,Georg, R.,Borries, D.,Renwick, D. (deposition date: 2020-04-03, release date: 2021-03-10, Last modification date: 2024-03-06)

• Primary citation: Horne, C.R.,Venugopal, H.,Panjikar, S.,Wood, D.M.,Henrickson, A.,Brookes, E.,North, R.A.,Murphy, J.M.,Friemann, R.,Griffin, M.D.W.,Ramm, G.,Demeler, B.,Dobson, R.C.J.; Mechanism of NanR gene repression and allosteric induction of bacterial sialic acid metabolism.; Nat Commun, 12:1988-1988, 2021; PubMed: 33790291; DOI: 10.1038/s41467-021-22253-6

Experimental method

ELECTRON MICROSCOPY (3.9 Å)